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The map label for this gene is adh [H]

Identifier: 154248660

GI number: 154248660

Start: 5263361

End: 5264395

Strand: Direct

Name: adh [H]

Synonym: Xaut_4742

Alternate gene names: 154248660

Gene position: 5263361-5264395 (Clockwise)

Preceding gene: 154248659

Following gene: 154248661

Centisome position: 99.14

GC content: 70.24

Gene sequence:

>1035_bases
GTGAACGCAGTCGCACTTTCCCCAAACCCGGGCGCCGGCCTGGCGGTGGACGCCACCGCGCTGCGCTTCGACCAGCGCGC
CACCAGCCCGGACGCTGTAAAGCCCCGCCTCGAACGACGCACGCTGTTCCGCACAAAGCCAGCCGACGCCTTGGTGGAAA
TCCGGGCCGCCGCCGTCAATCCGTCCGACGTGAAGGCCGCCATCGGCCTCATGCCCTATGCGGTGTTTCCCCGCACGCCG
GGGCGCGACTTCGCCGGCATCGTGATCGATGGCCCTTCCGACTGGCTCGGCAAGGCGGTGTACGGCTCGTCCGGCGACCT
CGGCATCCGCCGCGACGGCACCCACGCCACCCACCTCGTGGTGGAGGCGGACGCCCTGGTGGAAAAGCCTGAGGGCATCT
CGCTTCAGGAGGCGGCGGGCATCGGCGTGCCGTTCGTCACCGCCATCGAGGGCTTCCGCCGCGCCGGCCTGCCCCGGCCG
GGGGAGACCGTGCTGGTGCTGGGCGTCAACGGCAAGGTGGGTCAGGCTGCGGCGCAGATCGCCACCTGGCGCGGGGCGCG
GGTGGTCGGCGTGGTGCGCAAGGCCGAGCCCTATGGCGGCCATGCCAGCGGGCCGGTGACCCTCATCAATTCCTCCGCTC
AGGATGTAGCCTCCACGGTGAAAGAACTCACCGATGGGCGGGGCGCCGACATCGTCTTCAACACGGTGGGCGATCCCTAT
TACGCGGAAGGCACCGCATCCCTCGCCAAGACCGGGCGGCAGATCTTCATCGCGGCGGTGAACCGCATCGTCGAATTCGA
CATCTTCGCCTTCTATCGCGGCCGGCACACCTATGTGGGCATCGACACGCTGGCCCTGTCGTCCATCGAGACGGCGGACG
TGCTGCGCGAGCTGGCGCCGGGCTTCGCGGGCGGCCAGCTGCGGCCCTTCCCCATCACTGCGGACGGCGTCTTCGCCCTG
AAGGATGCGGGCGAGGCCTATGCCCGCGTGACCGGGTCCGCGCGCGATCGCGTCATCCTCGTGCCCGGCGCGTGA

Upstream 100 bases:

>100_bases
GGCCCGCGACCTCATCGGCCTGCCCACCCGCCTCGCCGACGCAAGAAGCGTCGCATGAGCGGCGCCCGCCCCCACTGCTT
GAAAACGTAAGGAGGTCCCC

Downstream 100 bases:

>100_bases
GGTGCTGCCATGAACGTCATGCGATTTGACCAGGCCCCGCCCTACCAGGCCCCCGGACATGCGCTGATGCACATGGTCCG
GCTCCAGGGCCGGGAGGCCG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNAVALSPNPGAGLAVDATALRFDQRATSPDAVKPRLERRTLFRTKPADALVEIRAAAVNPSDVKAAIGLMPYAVFPRTP
GRDFAGIVIDGPSDWLGKAVYGSSGDLGIRRDGTHATHLVVEADALVEKPEGISLQEAAGIGVPFVTAIEGFRRAGLPRP
GETVLVLGVNGKVGQAAAQIATWRGARVVGVVRKAEPYGGHASGPVTLINSSAQDVASTVKELTDGRGADIVFNTVGDPY
YAEGTASLAKTGRQIFIAAVNRIVEFDIFAFYRGRHTYVGIDTLALSSIETADVLRELAPGFAGGQLRPFPITADGVFAL
KDAGEAYARVTGSARDRVILVPGA

Sequences:

>Translated_344_residues
MNAVALSPNPGAGLAVDATALRFDQRATSPDAVKPRLERRTLFRTKPADALVEIRAAAVNPSDVKAAIGLMPYAVFPRTP
GRDFAGIVIDGPSDWLGKAVYGSSGDLGIRRDGTHATHLVVEADALVEKPEGISLQEAAGIGVPFVTAIEGFRRAGLPRP
GETVLVLGVNGKVGQAAAQIATWRGARVVGVVRKAEPYGGHASGPVTLINSSAQDVASTVKELTDGRGADIVFNTVGDPY
YAEGTASLAKTGRQIFIAAVNRIVEFDIFAFYRGRHTYVGIDTLALSSIETADVLRELAPGFAGGQLRPFPITADGVFAL
KDAGEAYARVTGSARDRVILVPGA
>Mature_344_residues
MNAVALSPNPGAGLAVDATALRFDQRATSPDAVKPRLERRTLFRTKPADALVEIRAAAVNPSDVKAAIGLMPYAVFPRTP
GRDFAGIVIDGPSDWLGKAVYGSSGDLGIRRDGTHATHLVVEADALVEKPEGISLQEAAGIGVPFVTAIEGFRRAGLPRP
GETVLVLGVNGKVGQAAAQIATWRGARVVGVVRKAEPYGGHASGPVTLINSSAQDVASTVKELTDGRGADIVFNTVGDPY
YAEGTASLAKTGRQIFIAAVNRIVEFDIFAFYRGRHTYVGIDTLALSSIETADVLRELAPGFAGGQLRPFPITADGVFAL
KDAGEAYARVTGSARDRVILVPGA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=273, Percent_Identity=24.5421245421245, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI13236495, Length=273, Percent_Identity=24.5421245421245, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI41872631, Length=280, Percent_Identity=28.9285714285714, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=191, Percent_Identity=30.8900523560209, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 35954; Mature: 35954

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVALSPNPGAGLAVDATALRFDQRATSPDAVKPRLERRTLFRTKPADALVEIRAAAVN
CCEEEECCCCCCCEEEEHHHHHHHCCCCCCCHHCHHHHHHHHHCCCCHHHHEEEHHCCCC
PSDVKAAIGLMPYAVFPRTPGRDFAGIVIDGPSDWLGKAVYGSSGDLGIRRDGTHATHLV
HHHHHHHHHHCCEEECCCCCCCCEEEEEEECCCHHHCCEEECCCCCCCEEECCCCEEEEE
VEADALVEKPEGISLQEAAGIGVPFVTAIEGFRRAGLPRPGETVLVLGVNGKVGQAAAQI
EEEHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
ATWRGARVVGVVRKAEPYGGHASGPVTLINSSAQDVASTVKELTDGRGADIVFNTVGDPY
HHCCCCEEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCE
YAEGTASLAKTGRQIFIAAVNRIVEFDIFAFYRGRHTYVGIDTLALSSIETADVLRELAP
ECCCCHHHHHCCCEEEEHHHHHHHHHEEEEEECCCEEEEEEHHHHHCCCHHHHHHHHHCC
GFAGGQLRPFPITADGVFALKDAGEAYARVTGSARDRVILVPGA
CCCCCCEECEEECCCCEEEEECCCCCEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MNAVALSPNPGAGLAVDATALRFDQRATSPDAVKPRLERRTLFRTKPADALVEIRAAAVN
CCEEEECCCCCCCEEEEHHHHHHHCCCCCCCHHCHHHHHHHHHCCCCHHHHEEEHHCCCC
PSDVKAAIGLMPYAVFPRTPGRDFAGIVIDGPSDWLGKAVYGSSGDLGIRRDGTHATHLV
HHHHHHHHHHCCEEECCCCCCCCEEEEEEECCCHHHCCEEECCCCCCCEEECCCCEEEEE
VEADALVEKPEGISLQEAAGIGVPFVTAIEGFRRAGLPRPGETVLVLGVNGKVGQAAAQI
EEEHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
ATWRGARVVGVVRKAEPYGGHASGPVTLINSSAQDVASTVKELTDGRGADIVFNTVGDPY
HHCCCCEEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCE
YAEGTASLAKTGRQIFIAAVNRIVEFDIFAFYRGRHTYVGIDTLALSSIETADVLRELAP
ECCCCHHHHHCCCEEEEHHHHHHHHHEEEEEECCCEEEEEEHHHHHCCCHHHHHHHHHCC
GFAGGQLRPFPITADGVFALKDAGEAYARVTGSARDRVILVPGA
CCCCCCEECEEECCCCEEEEECCCCCEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]