BacMap

Definition	Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession	NC_009720
Length	5,308,934

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The map label for this gene is gra-orf6 [H]

Identifier: 154248658

GI number: 154248658

Start: 5261574

End: 5262392

Strand: Direct

Name: gra-orf6 [H]

Synonym: Xaut_4740

Alternate gene names: 154248658

Gene position: 5261574-5262392 (Clockwise)

Preceding gene: 154248657

Following gene: 154248659

Centisome position: 99.11

GC content: 72.16

Gene sequence:

>819_bases
ATGACATCCGCAGCCGCCCGCATCGCGGGCGAGGCCGCCGGCACGCCCGTGCCCCACCGGCCCCTTTATCCGCGCTCGCT
GGAGGGCAAGCTCGCCCTCGTGGTCGGGGGCGCGGGTGCCATCGGCGGCGCCACCAGCCGCATGCTTGCCCAGGCCGGCG
CGACGGTGGCGGTGACGCACATGCCGTCCGAGGCCGACGCCCGCGCCGCCCAGGCCCTCGTGAGCGAATTGGGCGACGGC
CACGCCGCCTTCCCGGCGGACGTGAGCGACACCGAAACGCTCATCGCCGTCCGCGACCAGATCGCGGCACGCTATGGCCG
CCTCGACATTCTGGTGAATGCGGCGGGCTTCACCCGGCCGGTGCCCCACGCCGACCTCGACGCGCTGACCGACGAACTGA
TCGACCGCATGTTCCAGGTGAACTGGCGCGGACAGTTCGCGAGCGTGCGCACCTTCGCCCCGCTGCTGAAGGCGTCGGGC
GACGGGCTGATCGTGTCCATCTCCTCCATCGCCGCCTTCACCGGCGTCGGCTCGTCCATCGCCTATTGCGCGGCCAAGGC
CGGCATCGACGTGATGACCAAGGCGCTCGCCCGGGCCCTCGCCCCGGAGATCCGCGTCCTCGCCATATCCCCCGGCGTGG
TCGACACCGCCTTCGTCCCCGGGCGCGGGGCGGACTTCAACGACAAGGTCACCCATTCCACCCCGCTCCGGCGGATCGCC
GAGGCGGACGACATCGCCGCCGCCATCACCGCCTGCGCCACCATGCTCGGCTACTCGACCGGACACATCATCCAGGTCGA
CGGCGGGCGGGCGTTGTGA

Upstream 100 bases:

>100_bases
CCTCGACTACCAATTCGTCATGGAGCCCGGCGTGGCGAAGCTGCCCCGGCCGCCGATCAAGTGATCCCGACGCCAGCCCC
TTAATTCAAAGAGGTCGATC

Downstream 100 bases:

>100_bases
GGGAGGTCTCCATGCGCGCGCCGAAGGACAAGGTCTTCATCACCTGCGCCATCACCGGCAACCTCACGCGGCCGGAGCAG
ACGCCCCATCTTCCCATCAC

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTSAAARIAGEAAGTPVPHRPLYPRSLEGKLALVVGGAGAIGGATSRMLAQAGATVAVTHMPSEADARAAQALVSELGDG
HAAFPADVSDTETLIAVRDQIAARYGRLDILVNAAGFTRPVPHADLDALTDELIDRMFQVNWRGQFASVRTFAPLLKASG
DGLIVSISSIAAFTGVGSSIAYCAAKAGIDVMTKALARALAPEIRVLAISPGVVDTAFVPGRGADFNDKVTHSTPLRRIA
EADDIAAAITACATMLGYSTGHIIQVDGGRAL

Sequences:

>Translated_272_residues
MTSAAARIAGEAAGTPVPHRPLYPRSLEGKLALVVGGAGAIGGATSRMLAQAGATVAVTHMPSEADARAAQALVSELGDG
HAAFPADVSDTETLIAVRDQIAARYGRLDILVNAAGFTRPVPHADLDALTDELIDRMFQVNWRGQFASVRTFAPLLKASG
DGLIVSISSIAAFTGVGSSIAYCAAKAGIDVMTKALARALAPEIRVLAISPGVVDTAFVPGRGADFNDKVTHSTPLRRIA
EADDIAAAITACATMLGYSTGHIIQVDGGRAL
>Mature_271_residues
TSAAARIAGEAAGTPVPHRPLYPRSLEGKLALVVGGAGAIGGATSRMLAQAGATVAVTHMPSEADARAAQALVSELGDGH
AAFPADVSDTETLIAVRDQIAARYGRLDILVNAAGFTRPVPHADLDALTDELIDRMFQVNWRGQFASVRTFAPLLKASGD
GLIVSISSIAAFTGVGSSIAYCAAKAGIDVMTKALARALAPEIRVLAISPGVVDTAFVPGRGADFNDKVTHSTPLRRIAE
ADDIAAAITACATMLGYSTGHIIQVDGGRAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=32.295719844358, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=30.6513409961686, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=28.8, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=29.7619047619048, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI83715985, Length=192, Percent_Identity=31.7708333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=31.3253012048193, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=30.3482587064677, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI142976729, Length=205, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=237, Percent_Identity=24.8945147679325, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=28.6852589641434, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=163, Percent_Identity=26.9938650306748, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI66933014, Length=183, Percent_Identity=30.6010928961749, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4503301, Length=268, Percent_Identity=24.2537313432836, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=33.0677290836653, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.8943089430894, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789378, Length=272, Percent_Identity=30.1470588235294, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=31.2252964426877, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789057, Length=271, Percent_Identity=28.4132841328413, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.8617886178862, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=31.5589353612167, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=29.4820717131474, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=33.6032388663968, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=32.4110671936759, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=31.7460317460317, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=33.0827067669173, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=207, Percent_Identity=35.2657004830918, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=28.515625, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=29.7397769516729, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=31.3432835820896, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=31.1740890688259, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.9245283018868, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=25.6038647342995, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=32.5670498084291, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=30.6818181818182, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=173, Percent_Identity=25.4335260115607, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=172, Percent_Identity=29.0697674418605, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=30.4832713754647, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=29.811320754717, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=30.8270676691729, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=194, Percent_Identity=31.4432989690722, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=202, Percent_Identity=30.1980198019802, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=28.6792452830189, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=28.2442748091603, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=265, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=30.1158301158301, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=28.5140562248996, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.8, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=29.9610894941634, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=28.90625, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=34.375, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=28.6274509803922, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281364892, Length=188, Percent_Identity=27.6595744680851, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=29.0196078431373, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649181, Length=169, Percent_Identity=27.2189349112426, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665243, Length=215, Percent_Identity=28.8372093023256, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27853; Mature: 27722

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAAARIAGEAAGTPVPHRPLYPRSLEGKLALVVGGAGAIGGATSRMLAQAGATVAVTH
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
MPSEADARAAQALVSELGDGHAAFPADVSDTETLIAVRDQIAARYGRLDILVNAAGFTRP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCC
VPHADLDALTDELIDRMFQVNWRGQFASVRTFAPLLKASGDGLIVSISSIAAFTGVGSSI
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCHHH
AYCAAKAGIDVMTKALARALAPEIRVLAISPGVVDTAFVPGRGADFNDKVTHSTPLRRIA
HHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHH
EADDIAAAITACATMLGYSTGHIIQVDGGRAL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
>Mature Secondary Structure 
TSAAARIAGEAAGTPVPHRPLYPRSLEGKLALVVGGAGAIGGATSRMLAQAGATVAVTH
CCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
MPSEADARAAQALVSELGDGHAAFPADVSDTETLIAVRDQIAARYGRLDILVNAAGFTRP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCC
VPHADLDALTDELIDRMFQVNWRGQFASVRTFAPLLKASGDGLIVSISSIAAFTGVGSSI
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCHHH
AYCAAKAGIDVMTKALARALAPEIRVLAISPGVVDTAFVPGRGADFNDKVTHSTPLRRIA
HHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHH
EADDIAAAITACATMLGYSTGHIIQVDGGRAL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 9831526 [H]