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The map label for this gene is mmgC [H]

Identifier: 154248630

GI number: 154248630

Start: 5225347

End: 5226540

Strand: Direct

Name: mmgC [H]

Synonym: Xaut_4712

Alternate gene names: 154248630

Gene position: 5225347-5226540 (Clockwise)

Preceding gene: 154248628

Following gene: 154248631

Centisome position: 98.43

GC content: 67.59

Gene sequence:

>1194_bases
ATGGCAGCCGCCACCAAGCCCGTGTTCGACTGGACCGACCCCTTCGACCTCAACGGCCAGCTCACCGAGGACGAGCGGCT
GGTGCGCGACACCGCGCGCGACTATGCGCAGGAGAAGCTGCTGCCCCGCGTCACCTCTGCCTATCTGGAGGAGCGGTTCG
ACCGCGAAATCATGAACGAGATGGGCGAATTGGGCCTGCTCGGCCCCACCATCCCGGCGGAATACGGCGGCGCGGGCCTC
GGCTATGTGTCCTACGGCCTTGCCGCGCGCGAGGTGGAGCGGGTGGATAGCGGCTACCGCTCGGCCATGAGCGTGCAGTC
CTCCCTCGTCATGCACCCCATCTACGCCTATGGCACCGAGGCCCAGCGCCAGAAGTATCTGCCGAAGCTCGCCACCGGCG
AGTGGATCGGCTGCTTCGGCCTCACCGAGCCGGATGCGGGTTCCGATCCCGCCGGCATGCGCACCCGCGCCGAGAAGATC
GACGGCGGCTATCGCCTGAACGGCGCCAAGATGTGGATCACCAATTCACCCATCGCCGACCTCGCGGTGGTGTGGGCGAA
GTCGGCGGCCCACGACAATGCCATCCGCGGCTTCGTGGTGGAGCGCGGCATGAAGGGCTTCTCCACCCCCAAGATCGAGG
GCAAGCTCTCGCTGCGCGCCTCCATCACCGGCGAGATCGTGCTGGAGGACGTGGAGATCCCCGAAGAGAACCTGCTGCCC
AACGTGTCCGGCCTTGCCGGCCCGTTCGGCTGCCTCAACCGGGCGCGCTACGGCATCGGCTGGGGCGCCATGGGCGCGGC
GGAGGCCTGCTTCGCCCAGGCCCGCCAATACACGCTGGACCGCAAGCAGTTCGGCAAGCCGCTGGCCGCCACCCAATTGG
TGCAGAAGAAGCTGGCGGACATGGCCACCGACATCGCCTTCGGCCTGCAGGCCTGCCTGCGCGTCGGCCGGCTGTTCGAG
GAAGGCCGCCTGCCGCCGGAGACCATCTCCTTCATCAAGCGCAACAATTGCGGCAAGGCGCTGGACATTGCCCGCACCGC
CCGCGACATGCACGGCGGCAACGGCATCTCCGCCGAATTCCACGTCATCCGCCACGCCGCGAACCTTGAGACCGTGAACA
CCTATGAGGGCACGCACGACATCCATGCGCTGATCCTCGGCCGCGGCATCACCGGCATCCAGGCGTTCTTCTGA

Upstream 100 bases:

>100_bases
TCCGCTCCCTTGACTGAGGCGAGATAATTATATACCGACTGGATGGAATGTAAATGGAGCCCGCGCTCACCGGCCGGGCC
CGCAGCGGGAGACGCACCCA

Downstream 100 bases:

>100_bases
GGAGTGGGAGGCGTCCCACTCCAGAACCACCGTCATGCCCGGGCTTGACCCGGGCATCCACGTCCCGCCGCCTGGCACCG
CGCGTCCTATAGGGACCCCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MAAATKPVFDWTDPFDLNGQLTEDERLVRDTARDYAQEKLLPRVTSAYLEERFDREIMNEMGELGLLGPTIPAEYGGAGL
GYVSYGLAAREVERVDSGYRSAMSVQSSLVMHPIYAYGTEAQRQKYLPKLATGEWIGCFGLTEPDAGSDPAGMRTRAEKI
DGGYRLNGAKMWITNSPIADLAVVWAKSAAHDNAIRGFVVERGMKGFSTPKIEGKLSLRASITGEIVLEDVEIPEENLLP
NVSGLAGPFGCLNRARYGIGWGAMGAAEACFAQARQYTLDRKQFGKPLAATQLVQKKLADMATDIAFGLQACLRVGRLFE
EGRLPPETISFIKRNNCGKALDIARTARDMHGGNGISAEFHVIRHAANLETVNTYEGTHDIHALILGRGITGIQAFF

Sequences:

>Translated_397_residues
MAAATKPVFDWTDPFDLNGQLTEDERLVRDTARDYAQEKLLPRVTSAYLEERFDREIMNEMGELGLLGPTIPAEYGGAGL
GYVSYGLAAREVERVDSGYRSAMSVQSSLVMHPIYAYGTEAQRQKYLPKLATGEWIGCFGLTEPDAGSDPAGMRTRAEKI
DGGYRLNGAKMWITNSPIADLAVVWAKSAAHDNAIRGFVVERGMKGFSTPKIEGKLSLRASITGEIVLEDVEIPEENLLP
NVSGLAGPFGCLNRARYGIGWGAMGAAEACFAQARQYTLDRKQFGKPLAATQLVQKKLADMATDIAFGLQACLRVGRLFE
EGRLPPETISFIKRNNCGKALDIARTARDMHGGNGISAEFHVIRHAANLETVNTYEGTHDIHALILGRGITGIQAFF
>Mature_396_residues
AAATKPVFDWTDPFDLNGQLTEDERLVRDTARDYAQEKLLPRVTSAYLEERFDREIMNEMGELGLLGPTIPAEYGGAGLG
YVSYGLAAREVERVDSGYRSAMSVQSSLVMHPIYAYGTEAQRQKYLPKLATGEWIGCFGLTEPDAGSDPAGMRTRAEKID
GGYRLNGAKMWITNSPIADLAVVWAKSAAHDNAIRGFVVERGMKGFSTPKIEGKLSLRASITGEIVLEDVEIPEENLLPN
VSGLAGPFGCLNRARYGIGWGAMGAAEACFAQARQYTLDRKQFGKPLAATQLVQKKLADMATDIAFGLQACLRVGRLFEE
GRLPPETISFIKRNNCGKALDIARTARDMHGGNGISAEFHVIRHAANLETVNTYEGTHDIHALILGRGITGIQAFF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=398, Percent_Identity=66.8341708542714, Blast_Score=556, Evalue=1e-158,
Organism=Homo sapiens, GI7669494, Length=378, Percent_Identity=65.3439153439153, Blast_Score=517, Evalue=1e-147,
Organism=Homo sapiens, GI226958412, Length=387, Percent_Identity=34.1085271317829, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI226958414, Length=348, Percent_Identity=34.1954022988506, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=33.1536388140162, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=31.9261213720317, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=32, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=32, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI76496475, Length=398, Percent_Identity=32.6633165829146, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4557235, Length=398, Percent_Identity=32.6633165829146, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=32.6815642458101, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=30.1587301587302, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=28.5340314136126, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1786223, Length=343, Percent_Identity=25.6559766763848, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081958, Length=388, Percent_Identity=24.7422680412371, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=388, Percent_Identity=65.2061855670103, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=33.1564986737401, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=32.7956989247312, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=30.0791556728232, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=407, Percent_Identity=30.4668304668305, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=28.9544235924933, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=29.5039164490862, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71985192, Length=312, Percent_Identity=32.6923076923077, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=252, Percent_Identity=34.5238095238095, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=28.7598944591029, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=31.5018315018315, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=32.9004329004329, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=389, Percent_Identity=26.2210796915167, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17551932, Length=265, Percent_Identity=26.7924528301887, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=265, Percent_Identity=25.6603773584906, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19920834, Length=399, Percent_Identity=62.65664160401, Blast_Score=505, Evalue=1e-143,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=32.0855614973262, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=32.171581769437, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=33.2446808510638, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=32.3529411764706, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=31.2169312169312, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281363737, Length=400, Percent_Identity=32, Blast_Score=161, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43311; Mature: 43180

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAATKPVFDWTDPFDLNGQLTEDERLVRDTARDYAQEKLLPRVTSAYLEERFDREIMNE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGELGLLGPTIPAEYGGAGLGYVSYGLAAREVERVDSGYRSAMSVQSSLVMHPIYAYGTE
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AQRQKYLPKLATGEWIGCFGLTEPDAGSDPAGMRTRAEKIDGGYRLNGAKMWITNSPIAD
HHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCEEECCEEEEEECCCHHH
LAVVWAKSAAHDNAIRGFVVERGMKGFSTPKIEGKLSLRASITGEIVLEDVEIPEENLLP
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCHHHCCC
NVSGLAGPFGCLNRARYGIGWGAMGAAEACFAQARQYTLDRKQFGKPLAATQLVQKKLAD
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHH
MATDIAFGLQACLRVGRLFEEGRLPPETISFIKRNNCGKALDIARTARDMHGGNGISAEF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHH
HVIRHAANLETVNTYEGTHDIHALILGRGITGIQAFF
HHHHHHCCCCEEECCCCCHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
AAATKPVFDWTDPFDLNGQLTEDERLVRDTARDYAQEKLLPRVTSAYLEERFDREIMNE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGELGLLGPTIPAEYGGAGLGYVSYGLAAREVERVDSGYRSAMSVQSSLVMHPIYAYGTE
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AQRQKYLPKLATGEWIGCFGLTEPDAGSDPAGMRTRAEKIDGGYRLNGAKMWITNSPIAD
HHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCEEECCEEEEEECCCHHH
LAVVWAKSAAHDNAIRGFVVERGMKGFSTPKIEGKLSLRASITGEIVLEDVEIPEENLLP
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCHHHCCC
NVSGLAGPFGCLNRARYGIGWGAMGAAEACFAQARQYTLDRKQFGKPLAATQLVQKKLAD
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHH
MATDIAFGLQACLRVGRLFEEGRLPPETISFIKRNNCGKALDIARTARDMHGGNGISAEF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHH
HVIRHAANLETVNTYEGTHDIHALILGRGITGIQAFF
HHHHHHCCCCEEECCCCCHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]