| Definition | Xanthobacter autotrophicus Py2 chromosome, complete genome. |
|---|---|
| Accession | NC_009720 |
| Length | 5,308,934 |
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The map label for this gene is mrcA [H]
Identifier: 154248588
GI number: 154248588
Start: 5164609
End: 5167023
Strand: Direct
Name: mrcA [H]
Synonym: Xaut_4669
Alternate gene names: 154248588
Gene position: 5164609-5167023 (Clockwise)
Preceding gene: 154248587
Following gene: 154248589
Centisome position: 97.28
GC content: 67.16
Gene sequence:
>2415_bases ATGCGGTTGATCTTGAGGTTTCTGGGGTTCGTGTTCGCGCTCACCACCGTGGTGCTTCTCGCCGGAGCCGCGGGCGCGAC CTATTTCGTGTGGAAATACTCCCAGGACCTCCCCGACTACTCCCAGCTGCAGAACTACGAGCCGCCGGTGATGACCCGCG TGCACGCCGCCGATGGCGCGCTGGTGGCCGAGTACGCCAAGCAGCGCCGCCTCTACATTCCCATCCAGTCCGTGCCCAAG CTGGTCATCGAGGCCTTCCTGTCGGCCGAGGACAAGAATTTCTACGAGCACGGCGGCATCGACCCCACCGGCATCTTCCG CGCCGCGGCGTTCTATTTCCAGAATTACGGCAAGAACGTCCGGCCCCAGGGCGCGTCCACCATCACCCAGCAGGTGGCCA AGAACTTCCTGCTCACCAACGAGGTGTCCCTCGACCGCAAGGTCAAGGAAGCGCTGCTCGCCCTGCGCATCGAGCGCACC TATTCCAAGGACCGGATCCTCGAGCTGTACCTCAACGAGATCTATCTCGGCATGGGCGCCTACGGCATCGCCGCCGCAGC GCTGGTGTATTTCGACAAGTCGGTGGACGAGCTGAACGTGCAGGAAGTGGCGTATCTTGCCGCCCTGCCGAAGGCCCCCT CCTCCTACAATCCGTTCCGCGACCGCTCCCGCGCCACCGATCGCCGCAACTGGGTGATCGACCGCATGGTGGAGAACGGC TTCGTCACCCCGCAGGAGGGCGAGGCGGCCAAGAAGTCGGGCCTGGACGTGACCCCGCGGGCCACCGGCGCGCAGATCTT CGCCGCGGAATATTACGCTGAGGAAGTGCGCCGGCAAATCTACGAGCGCTATGGCGAGCGCAAGCTCTACGAGGGCGGCC TCTCGGTGCGCACGCCGCTCGATCCCAAGCTCCAGGTGCTGGCCAAGAAGACCCTCACCGACGGCCTCGTGCGCTATGAC GAGGAGCGCGGCTGGCGCAAGCCCGTCACCCATGTGGACCTCTCCGGCGGGGTCGACTGGGGCGTGAAGCTGGGCGAGGT CAAGGAACTGACCGACATTCCCTGGCGCCTCGCCATCGTGCTGGACGTGGGCAAGGACAATGCGCGCATCGGCCTGCAGC CGCCGCGCACCAAGTCCGGCGCCCGCTCCACCGACCGCGAGGTGGGCCTGATCCCCGTGGACGGCGCCAAATGGACCCGC CGCCCTCTGTCGCAGGTGCTGAAGCCCGGCGACGTGATCTATGTGGAGCCCTTGGGCGACCGCACCGGCCAGTGGCGCCT GCGCCAGCTGCCGGGCGTGGAAGGCGCCATGGTGGTCATGGAGCCCACCACCGGCCGCGTGCTCGCCATCTCCGGCGGCT TCTCCTACGACGAGAGCCAGTTCAACCGCGCCACCCAGGCCATGCGCCAGCCCGGTTCCTCGTTCAAGCCGTTCGTCTAT TCGGCGGCGCTGGATAACGGCTACACCCCCTCCACCATCGTCATGGACGCCCCGTTCGAGCTGGAGCAGCAGGGCCAGGC CACGTGGCGGCCGGAAAACTATTCCGGCAAGTTCTATGGCCCGCAGACCCTGCGCTTCGGCCTGGAGCAGTCGCGCAACG TGATGACCGTGCGTCTCGCCAATGACGTGGGAATGCCCATCGTCGCCGAATACGCCAAGCGCTTCGGTATCTATGACGAC ATGCCGCCCTATCTCGCCATGGCGCTGGGATCGGGCGAGACCACCCTTCTGCGCATGACCGGCGCCTACGCCATGATCGC CAATGGCGGGCGCAAGGTGACGCCCTCGCTCATCGACCGCATCCAGGACCGCTACGGCCACACCATCTTCAAGCACGACG AGCGCGAATGCCGCGGCTGCGAGGCCGACAAGTGGGACAACCAGCCCGAGCCGAGCTTGGTGGACCGCCGCCCGGTGGTG CTCGACCCCATGACCGCCTACCAGATCACCTCCATGATGGAGGGCGTGGTCCAGCGCGGCACCGGCACCGCGCTGAAGGA GCTGGGCAAGCCCATCGCCGGCAAGACCGGCACCACCAACGAAGAGAAGGACGCCTGGTTCATCGGCTTCACGCCGGAAA TCGTGGTGGGCGTCTATCTCGGCTACGACAAGCCCAAGCCCATGGGCAAGGGCTCCACCGGCGGCCTCATCTCGGCGCCC ATCGTGCGCGACTTCATGAAGACCGCCATCGCCGACCGCCCGGCCATCCCGTTCCGGGTCCCGGCCGGCATCAAGCTGGT GCGCATCGACCGCAAGAGCGGCCAGCGTGCCGGCCCCGGCGACAGCTCCATCCTGGAGGCCTTCAAGCCCGGCACCGCCC CGCCCGACGGCTATAGCGTGGCCGGCTATTCCGGCACCGACGGCTCCTCGCCCGAGCCCAGCGCCCCCGTGCGCACCGGA GGCGGGCTCTACTGA
Upstream 100 bases:
>100_bases CTGCCGGCACCGGCCCCGCACTTTGGGGCCTTCGCACGGGAGTGAAGTCGCGCTATGCGGTGCCGCGCCTGATGGGGCGC CGTGGGAGGGAACCGGCGAA
Downstream 100 bases:
>100_bases GCCCGCGCCAGCCGCGGAACCCGACCGGAGCCATCCCTTTTCCCGGCAGCTGGAGCTGCGTTAACGAAGACTTGCGGCTT TCTGTACAACACCTGCGGAA
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 804; Mature: 804
Protein sequence:
>804_residues MRLILRFLGFVFALTTVVLLAGAAGATYFVWKYSQDLPDYSQLQNYEPPVMTRVHAADGALVAEYAKQRRLYIPIQSVPK LVIEAFLSAEDKNFYEHGGIDPTGIFRAAAFYFQNYGKNVRPQGASTITQQVAKNFLLTNEVSLDRKVKEALLALRIERT YSKDRILELYLNEIYLGMGAYGIAAAALVYFDKSVDELNVQEVAYLAALPKAPSSYNPFRDRSRATDRRNWVIDRMVENG FVTPQEGEAAKKSGLDVTPRATGAQIFAAEYYAEEVRRQIYERYGERKLYEGGLSVRTPLDPKLQVLAKKTLTDGLVRYD EERGWRKPVTHVDLSGGVDWGVKLGEVKELTDIPWRLAIVLDVGKDNARIGLQPPRTKSGARSTDREVGLIPVDGAKWTR RPLSQVLKPGDVIYVEPLGDRTGQWRLRQLPGVEGAMVVMEPTTGRVLAISGGFSYDESQFNRATQAMRQPGSSFKPFVY SAALDNGYTPSTIVMDAPFELEQQGQATWRPENYSGKFYGPQTLRFGLEQSRNVMTVRLANDVGMPIVAEYAKRFGIYDD MPPYLAMALGSGETTLLRMTGAYAMIANGGRKVTPSLIDRIQDRYGHTIFKHDERECRGCEADKWDNQPEPSLVDRRPVV LDPMTAYQITSMMEGVVQRGTGTALKELGKPIAGKTGTTNEEKDAWFIGFTPEIVVGVYLGYDKPKPMGKGSTGGLISAP IVRDFMKTAIADRPAIPFRVPAGIKLVRIDRKSGQRAGPGDSSILEAFKPGTAPPDGYSVAGYSGTDGSSPEPSAPVRTG GGLY
Sequences:
>Translated_804_residues MRLILRFLGFVFALTTVVLLAGAAGATYFVWKYSQDLPDYSQLQNYEPPVMTRVHAADGALVAEYAKQRRLYIPIQSVPK LVIEAFLSAEDKNFYEHGGIDPTGIFRAAAFYFQNYGKNVRPQGASTITQQVAKNFLLTNEVSLDRKVKEALLALRIERT YSKDRILELYLNEIYLGMGAYGIAAAALVYFDKSVDELNVQEVAYLAALPKAPSSYNPFRDRSRATDRRNWVIDRMVENG FVTPQEGEAAKKSGLDVTPRATGAQIFAAEYYAEEVRRQIYERYGERKLYEGGLSVRTPLDPKLQVLAKKTLTDGLVRYD EERGWRKPVTHVDLSGGVDWGVKLGEVKELTDIPWRLAIVLDVGKDNARIGLQPPRTKSGARSTDREVGLIPVDGAKWTR RPLSQVLKPGDVIYVEPLGDRTGQWRLRQLPGVEGAMVVMEPTTGRVLAISGGFSYDESQFNRATQAMRQPGSSFKPFVY SAALDNGYTPSTIVMDAPFELEQQGQATWRPENYSGKFYGPQTLRFGLEQSRNVMTVRLANDVGMPIVAEYAKRFGIYDD MPPYLAMALGSGETTLLRMTGAYAMIANGGRKVTPSLIDRIQDRYGHTIFKHDERECRGCEADKWDNQPEPSLVDRRPVV LDPMTAYQITSMMEGVVQRGTGTALKELGKPIAGKTGTTNEEKDAWFIGFTPEIVVGVYLGYDKPKPMGKGSTGGLISAP IVRDFMKTAIADRPAIPFRVPAGIKLVRIDRKSGQRAGPGDSSILEAFKPGTAPPDGYSVAGYSGTDGSSPEPSAPVRTG GGLY >Mature_804_residues MRLILRFLGFVFALTTVVLLAGAAGATYFVWKYSQDLPDYSQLQNYEPPVMTRVHAADGALVAEYAKQRRLYIPIQSVPK LVIEAFLSAEDKNFYEHGGIDPTGIFRAAAFYFQNYGKNVRPQGASTITQQVAKNFLLTNEVSLDRKVKEALLALRIERT YSKDRILELYLNEIYLGMGAYGIAAAALVYFDKSVDELNVQEVAYLAALPKAPSSYNPFRDRSRATDRRNWVIDRMVENG FVTPQEGEAAKKSGLDVTPRATGAQIFAAEYYAEEVRRQIYERYGERKLYEGGLSVRTPLDPKLQVLAKKTLTDGLVRYD EERGWRKPVTHVDLSGGVDWGVKLGEVKELTDIPWRLAIVLDVGKDNARIGLQPPRTKSGARSTDREVGLIPVDGAKWTR RPLSQVLKPGDVIYVEPLGDRTGQWRLRQLPGVEGAMVVMEPTTGRVLAISGGFSYDESQFNRATQAMRQPGSSFKPFVY SAALDNGYTPSTIVMDAPFELEQQGQATWRPENYSGKFYGPQTLRFGLEQSRNVMTVRLANDVGMPIVAEYAKRFGIYDD MPPYLAMALGSGETTLLRMTGAYAMIANGGRKVTPSLIDRIQDRYGHTIFKHDERECRGCEADKWDNQPEPSLVDRRPVV LDPMTAYQITSMMEGVVQRGTGTALKELGKPIAGKTGTTNEEKDAWFIGFTPEIVVGVYLGYDKPKPMGKGSTGGLISAP IVRDFMKTAIADRPAIPFRVPAGIKLVRIDRKSGQRAGPGDSSILEAFKPGTAPPDGYSVAGYSGTDGSSPEPSAPVRTG GGLY
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=854, Percent_Identity=35.1288056206089, Blast_Score=450, Evalue=1e-127, Organism=Escherichia coli, GI1786343, Length=281, Percent_Identity=33.0960854092527, Blast_Score=142, Evalue=8e-35, Organism=Escherichia coli, GI1788867, Length=210, Percent_Identity=32.8571428571429, Blast_Score=102, Evalue=1e-22, Organism=Escherichia coli, GI1789601, Length=156, Percent_Identity=39.7435897435897, Blast_Score=96, Evalue=1e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 88860; Mature: 88860
Theoretical pI: Translated: 9.21; Mature: 9.21
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLILRFLGFVFALTTVVLLAGAAGATYFVWKYSQDLPDYSQLQNYEPPVMTRVHAADGA CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCHHEEEECCCCH LVAEYAKQRRLYIPIQSVPKLVIEAFLSAEDKNFYEHGGIDPTGIFRAAAFYFQNYGKNV HHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCC RPQGASTITQQVAKNFLLTNEVSLDRKVKEALLALRIERTYSKDRILELYLNEIYLGMGA CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCH YGIAAAALVYFDKSVDELNVQEVAYLAALPKAPSSYNPFRDRSRATDRRNWVIDRMVENG HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCC FVTPQEGEAAKKSGLDVTPRATGAQIFAAEYYAEEVRRQIYERYGERKLYEGGLSVRTPL CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEECCCC DPKLQVLAKKTLTDGLVRYDEERGWRKPVTHVDLSGGVDWGVKLGEVKELTDIPWRLAIV CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCEEEEEE LDVGKDNARIGLQPPRTKSGARSTDREVGLIPVDGAKWTRRPLSQVLKPGDVIYVEPLGD EEECCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEEECCC RTGQWRLRQLPGVEGAMVVMEPTTGRVLAISGGFSYDESQFNRATQAMRQPGSSFKPFVY CCCCCHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEE SAALDNGYTPSTIVMDAPFELEQQGQATWRPENYSGKFYGPQTLRFGLEQSRNVMTVRLA EEHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCEECHHHHHHHHHCCCCEEEEEEC NDVGMPIVAEYAKRFGIYDDMPPYLAMALGSGETTLLRMTGAYAMIANGGRKVTPSLIDR CCCCCHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEEEECCEEEEECCCCEECHHHHHH IQDRYGHTIFKHDERECRGCEADKWDNQPEPSLVDRRPVVLDPMTAYQITSMMEGVVQRG HHHHHCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCC TGTALKELGKPIAGKTGTTNEEKDAWFIGFTPEIVVGVYLGYDKPKPMGKGSTGGLISAP CCHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHEEEEEECCCCCCCCCCCCCCCEEEHH IVRDFMKTAIADRPAIPFRVPAGIKLVRIDRKSGQRAGPGDSSILEAFKPGTAPPDGYSV HHHHHHHHHHCCCCCCCEECCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCEE AGYSGTDGSSPEPSAPVRTGGGLY CCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MRLILRFLGFVFALTTVVLLAGAAGATYFVWKYSQDLPDYSQLQNYEPPVMTRVHAADGA CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCHHEEEECCCCH LVAEYAKQRRLYIPIQSVPKLVIEAFLSAEDKNFYEHGGIDPTGIFRAAAFYFQNYGKNV HHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCC RPQGASTITQQVAKNFLLTNEVSLDRKVKEALLALRIERTYSKDRILELYLNEIYLGMGA CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCH YGIAAAALVYFDKSVDELNVQEVAYLAALPKAPSSYNPFRDRSRATDRRNWVIDRMVENG HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCC FVTPQEGEAAKKSGLDVTPRATGAQIFAAEYYAEEVRRQIYERYGERKLYEGGLSVRTPL CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEECCCC DPKLQVLAKKTLTDGLVRYDEERGWRKPVTHVDLSGGVDWGVKLGEVKELTDIPWRLAIV CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCEEEEEE LDVGKDNARIGLQPPRTKSGARSTDREVGLIPVDGAKWTRRPLSQVLKPGDVIYVEPLGD EEECCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEEECCC RTGQWRLRQLPGVEGAMVVMEPTTGRVLAISGGFSYDESQFNRATQAMRQPGSSFKPFVY CCCCCHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEE SAALDNGYTPSTIVMDAPFELEQQGQATWRPENYSGKFYGPQTLRFGLEQSRNVMTVRLA EEHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCEECHHHHHHHHHCCCCEEEEEEC NDVGMPIVAEYAKRFGIYDDMPPYLAMALGSGETTLLRMTGAYAMIANGGRKVTPSLIDR CCCCCHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEEEECCEEEEECCCCEECHHHHHH IQDRYGHTIFKHDERECRGCEADKWDNQPEPSLVDRRPVVLDPMTAYQITSMMEGVVQRG HHHHHCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCC TGTALKELGKPIAGKTGTTNEEKDAWFIGFTPEIVVGVYLGYDKPKPMGKGSTGGLISAP CCHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHEEEEEECCCCCCCCCCCCCCCEEEHH IVRDFMKTAIADRPAIPFRVPAGIKLVRIDRKSGQRAGPGDSSILEAFKPGTAPPDGYSV HHHHHHHHHHCCCCCCCEECCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCEE AGYSGTDGSSPEPSAPVRTGGGLY CCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]