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The map label for this gene is cusB [H]

Identifier: 154248512

GI number: 154248512

Start: 5079048

End: 5080481

Strand: Reverse

Name: cusB [H]

Synonym: Xaut_4592

Alternate gene names: 154248512

Gene position: 5080481-5079048 (Counterclockwise)

Preceding gene: 154248513

Following gene: 154248511

Centisome position: 95.7

GC content: 72.04

Gene sequence:

>1434_bases
ATGAAACGGGCCGTCCTTCGGGGCCTCACCCTCGCCGCCCTTCTGGCGGCGGGGGCCGGAGGCTATTGGGCCGGGCATCG
CGGCTTCGCGATCCCCGGCTCCTCCACCCTGTTCGCCACGACCGTCGCCGCTGAAACGCCGCCGCCCCCTTCGGGGCCGG
TCATCTATTACAAGGACCCCGACGGGCGGCCCGCTTATTCCGCGGCACCCACCCGGACCACCGGCGGGCGCGCCTTCCTG
CCCGTCCGGGCGAGCGAGGAGGGGAGCTTCGAGGAGACGCCCCCCGCCGATGCCGCCATGTCCTCTGCCGCCATGTCCCC
CGGCACAAGCGAGAGGCGCATCCTTTACTACCGCAACCCTATGGGCCTGCCGGACACCTCGCCGGTGCCAAAGAAGGACG
GCATGGGGATGGACTACATCCCTGTCTATGACGACGAGGCGGAGGACGGTCCCGTCGTGAAGATCCCGCCGGGCAGGCTC
CAGCGCACCGGGGTGCGGACGCAGGCGGCGGAGCGGCGTCCCCTCGACCGGCGGGTGCGGGTGCCGGGGATGGTGCAGCT
CGACGAGCGGCGCATCGCCGTGGTGGCGACCCGCAGCCCGGCCTTCCTCGACGCGGTGGCGAACGTCACCACCGGCGACC
GGGTGGTGAAGGGGCAGGCACTGGCGCGGCTCTATGCGCCGGACATCGCCACCGCGGGCGCGCAATACGTCACCGACCTC
AATGGCGGCGCGCGCGGCGCATCCGCCGGCGGCGGGCGCCAACGCCTGGAGAATCTCGGCGTTCCGGCCGAGGCCATCGC
CGAGATCGAGCGCACACGCAAGGTGCCCCTGTCCATGACCTGGCGGGCGATGCGCGACGGCGTCGTGCTGGAGCGCAATG
CCGTGGACGGGATGAGAGCGGAGCCCGGCGCCGTCCTGTTCCGCATCGCCGACATCTCCACCCTGTGGGTGCTGGCGGAC
GTGCCGGAGCACGACCTCGGAGCGGTGCGGATCGGCGCGCCGGCCAGCGTGCGTGTCCGCGGCCGGCCGGGCGTTGCATT
CGACGGGCAGGTGTCCCTCGTCTATCCCCAGGTGAGCGAGGCGACGCGCACCGCCCACGTGCGCATCGAGATCGCCAATC
CGGACGGCGTTCTCCTGCCCAACATGTATGCCGATGTGGCGATCGGCACCGGCGACGCCGCCCCCGTACTCGCCGTTCCC
GACGACGCGGTGATCGACACCGGCATGCGGCAGGTGGTGATCCTCGAGCGGGGCGAGGGCCGGTTCGAGCCGCGCGAGGT
GAAAGTCGGCCGGCGCGGGGAAGGCTTCATCGAGATCCGCGACGGCCTCGCCGAGGGCGACCTTGTGGTGGTGGCGGCGA
ACTTCCTGATCGACGCGGAGAGCAACCTGAAGGCCGCCCTGCGTGGCCTCGCGCCCGTGGAGACGCAGCCATGA

Upstream 100 bases:

>100_bases
CCAATCTGATGATGGCTGGCGGCTGGCGGCTCTCCCTCGGCGCCAAGATCCAGGGCGAGACCGGCACGATCGAGAGCAAG
CTGGTCCTGAAGGCCGTGCC

Downstream 100 bases:

>100_bases
TCGCCCGCCTCATCGCATGGTCGGCGCGCAATTTGGTGCTGGTCCTGGTCGGCACCGCCTTCGCCGTGGCCGCCGGCCTC
TATGCCCTGCGCACCCTGCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MKRAVLRGLTLAALLAAGAGGYWAGHRGFAIPGSSTLFATTVAAETPPPPSGPVIYYKDPDGRPAYSAAPTRTTGGRAFL
PVRASEEGSFEETPPADAAMSSAAMSPGTSERRILYYRNPMGLPDTSPVPKKDGMGMDYIPVYDDEAEDGPVVKIPPGRL
QRTGVRTQAAERRPLDRRVRVPGMVQLDERRIAVVATRSPAFLDAVANVTTGDRVVKGQALARLYAPDIATAGAQYVTDL
NGGARGASAGGGRQRLENLGVPAEAIAEIERTRKVPLSMTWRAMRDGVVLERNAVDGMRAEPGAVLFRIADISTLWVLAD
VPEHDLGAVRIGAPASVRVRGRPGVAFDGQVSLVYPQVSEATRTAHVRIEIANPDGVLLPNMYADVAIGTGDAAPVLAVP
DDAVIDTGMRQVVILERGEGRFEPREVKVGRRGEGFIEIRDGLAEGDLVVVAANFLIDAESNLKAALRGLAPVETQP

Sequences:

>Translated_477_residues
MKRAVLRGLTLAALLAAGAGGYWAGHRGFAIPGSSTLFATTVAAETPPPPSGPVIYYKDPDGRPAYSAAPTRTTGGRAFL
PVRASEEGSFEETPPADAAMSSAAMSPGTSERRILYYRNPMGLPDTSPVPKKDGMGMDYIPVYDDEAEDGPVVKIPPGRL
QRTGVRTQAAERRPLDRRVRVPGMVQLDERRIAVVATRSPAFLDAVANVTTGDRVVKGQALARLYAPDIATAGAQYVTDL
NGGARGASAGGGRQRLENLGVPAEAIAEIERTRKVPLSMTWRAMRDGVVLERNAVDGMRAEPGAVLFRIADISTLWVLAD
VPEHDLGAVRIGAPASVRVRGRPGVAFDGQVSLVYPQVSEATRTAHVRIEIANPDGVLLPNMYADVAIGTGDAAPVLAVP
DDAVIDTGMRQVVILERGEGRFEPREVKVGRRGEGFIEIRDGLAEGDLVVVAANFLIDAESNLKAALRGLAPVETQP
>Mature_477_residues
MKRAVLRGLTLAALLAAGAGGYWAGHRGFAIPGSSTLFATTVAAETPPPPSGPVIYYKDPDGRPAYSAAPTRTTGGRAFL
PVRASEEGSFEETPPADAAMSSAAMSPGTSERRILYYRNPMGLPDTSPVPKKDGMGMDYIPVYDDEAEDGPVVKIPPGRL
QRTGVRTQAAERRPLDRRVRVPGMVQLDERRIAVVATRSPAFLDAVANVTTGDRVVKGQALARLYAPDIATAGAQYVTDL
NGGARGASAGGGRQRLENLGVPAEAIAEIERTRKVPLSMTWRAMRDGVVLERNAVDGMRAEPGAVLFRIADISTLWVLAD
VPEHDLGAVRIGAPASVRVRGRPGVAFDGQVSLVYPQVSEATRTAHVRIEIANPDGVLLPNMYADVAIGTGDAAPVLAVP
DDAVIDTGMRQVVILERGEGRFEPREVKVGRRGEGFIEIRDGLAEGDLVVVAANFLIDAESNLKAALRGLAPVETQP

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=362, Percent_Identity=34.2541436464088, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI87081796, Length=152, Percent_Identity=34.8684210526316, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50531; Mature: 50531

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVLRGLTLAALLAAGAGGYWAGHRGFAIPGSSTLFATTVAAETPPPPSGPVIYYKDP
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCCCCEEEEECC
DGRPAYSAAPTRTTGGRAFLPVRASEEGSFEETPPADAAMSSAAMSPGTSERRILYYRNP
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECC
MGLPDTSPVPKKDGMGMDYIPVYDDEAEDGPVVKIPPGRLQRTGVRTQAAERRPLDRRVR
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCHHHCCCHHHHHHCCCCHHHCC
VPGMVQLDERRIAVVATRSPAFLDAVANVTTGDRVVKGQALARLYAPDIATAGAQYVTDL
CCCEEEECCCEEEEEEECCCHHHHHHHCCCCCCEEECCHHHHHHHCCCHHHCCCCEEEEC
NGGARGASAGGGRQRLENLGVPAEAIAEIERTRKVPLSMTWRAMRDGVVLERNAVDGMRA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHCCEEEEECCCCCCCC
EPGAVLFRIADISTLWVLADVPEHDLGAVRIGAPASVRVRGRPGVAFDGQVSLVYPQVSE
CCCEEEEEEECCEEEEEEEECCCCCCCEEEECCCCEEEECCCCCEEECCEEEEEECCCCC
ATRTAHVRIEIANPDGVLLPNMYADVAIGTGDAAPVLAVPDDAVIDTGMRQVVILERGEG
CCEEEEEEEEEECCCCEECCCCEEEEEECCCCCCCEEECCCCHHHHCCCEEEEEEECCCC
RFEPREVKVGRRGEGFIEIRDGLAEGDLVVVAANFLIDAESNLKAALRGLAPVETQP
CCCCCEEECCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKRAVLRGLTLAALLAAGAGGYWAGHRGFAIPGSSTLFATTVAAETPPPPSGPVIYYKDP
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCCCCEEEEECC
DGRPAYSAAPTRTTGGRAFLPVRASEEGSFEETPPADAAMSSAAMSPGTSERRILYYRNP
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECC
MGLPDTSPVPKKDGMGMDYIPVYDDEAEDGPVVKIPPGRLQRTGVRTQAAERRPLDRRVR
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCHHHCCCHHHHHHCCCCHHHCC
VPGMVQLDERRIAVVATRSPAFLDAVANVTTGDRVVKGQALARLYAPDIATAGAQYVTDL
CCCEEEECCCEEEEEEECCCHHHHHHHCCCCCCEEECCHHHHHHHCCCHHHCCCCEEEEC
NGGARGASAGGGRQRLENLGVPAEAIAEIERTRKVPLSMTWRAMRDGVVLERNAVDGMRA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHCCEEEEECCCCCCCC
EPGAVLFRIADISTLWVLADVPEHDLGAVRIGAPASVRVRGRPGVAFDGQVSLVYPQVSE
CCCEEEEEEECCEEEEEEEECCCCCCCEEEECCCCEEEECCCCCEEECCEEEEEECCCCC
ATRTAHVRIEIANPDGVLLPNMYADVAIGTGDAAPVLAVPDDAVIDTGMRQVVILERGEG
CCEEEEEEEEEECCCCEECCCCEEEEEECCCCCCCEEECCCCHHHHCCCEEEEEEECCCC
RFEPREVKVGRRGEGFIEIRDGLAEGDLVVVAANFLIDAESNLKAALRGLAPVETQP
CCCCCEEECCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]