Click here to switch to the map view.

The map label for this gene is sufC [H]

Identifier: 154248388

GI number: 154248388

Start: 4958972

End: 4959721

Strand: Reverse

Name: sufC [H]

Synonym: Xaut_4468

Alternate gene names: 154248388

Gene position: 4959721-4958972 (Counterclockwise)

Preceding gene: 154248389

Following gene: 154248387

Centisome position: 93.42

GC content: 66.13

Gene sequence:

>750_bases
ATGCTCGAAATCAAGAATCTCCACGCCCGCATTGGCGACAACGAGATCCTCAAGGGCCTCACCCTCACTGTCCCGGCGGG
GGAGGTGCATGCCATCATGGGGCCGAACGGCTCCGGCAAGTCCACCCTGTCCTATGTCCTCTCGGGCAAGCCGGACTATG
AGGTCACCGAGGGCACCGCCACCTTCAACGGGCAGGACATCCTCTCCCTCGCCCCCGAAGAGCGGGCGGCGGCGGGCGTG
TTCCTCGCCTTCCAGTATCCCATCGAGATCCCCGGCGTCGCCAACATGCAGTTCCTGCGCGCCGCCATGAACGCGCAGAA
GAAGGCGCGCGGGGAGGAGGAAATCTCCACCCCCGACTTCCTCAAGCTGGTGCGCGCCAAGGCCCCCGACCTCGGCATCA
CCCAGGACATGCTGCGGCGCGGGGTCAACGTGGGGTTCTCCGGCGGCGAGAAGAAGCGCAACGAAATCCTCCAGATGGCG
CTGCTGGAGCCCAAGCTGTGCATCCTCGACGAGACCGATTCCGGCCTCGACATCGATGCGCTGAAGGTGGTGGCGCAGGG
GGTGAACGCCCTTCGCTCGCCCGACCGCGCCATGCTGGTCATCACCCATTACCAGCGCCTGCTCGACCATATCGTGCCGG
ATGTGGTGCATGTGATGCACAAGGGCCGCATCGTCCGCTCCGGCGGCGCCGAGCTGGCGCTGGAGCTGGAGGAATCCGGC
TATGCCGCCTACGGGCAGGATGCGGCGTGA

Upstream 100 bases:

>100_bases
CAAGGCCGGGCATGACGGCTTCCAGAACGACGCGGGGCGCGGCCCCGCAGCGCTGACATTCCCGCCCGGCCCGGCCGTGG
CGCACCAACGGACACAGCAC

Downstream 100 bases:

>100_bases
GCGCGGCCATGAACATTCCCGTCCGTCCCGCCCGCACACCGGCCGAAGACGCCATCGCCGCCACGCTCCAGGCCCGGCTC
GCCGTCGCGGCCGGGCAGGG

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLEIKNLHARIGDNEILKGLTLTVPAGEVHAIMGPNGSGKSTLSYVLSGKPDYEVTEGTATFNGQDILSLAPEERAAAGV
FLAFQYPIEIPGVANMQFLRAAMNAQKKARGEEEISTPDFLKLVRAKAPDLGITQDMLRRGVNVGFSGGEKKRNEILQMA
LLEPKLCILDETDSGLDIDALKVVAQGVNALRSPDRAMLVITHYQRLLDHIVPDVVHVMHKGRIVRSGGAELALELEESG
YAAYGQDAA

Sequences:

>Translated_249_residues
MLEIKNLHARIGDNEILKGLTLTVPAGEVHAIMGPNGSGKSTLSYVLSGKPDYEVTEGTATFNGQDILSLAPEERAAAGV
FLAFQYPIEIPGVANMQFLRAAMNAQKKARGEEEISTPDFLKLVRAKAPDLGITQDMLRRGVNVGFSGGEKKRNEILQMA
LLEPKLCILDETDSGLDIDALKVVAQGVNALRSPDRAMLVITHYQRLLDHIVPDVVHVMHKGRIVRSGGAELALELEESG
YAAYGQDAA
>Mature_249_residues
MLEIKNLHARIGDNEILKGLTLTVPAGEVHAIMGPNGSGKSTLSYVLSGKPDYEVTEGTATFNGQDILSLAPEERAAAGV
FLAFQYPIEIPGVANMQFLRAAMNAQKKARGEEEISTPDFLKLVRAKAPDLGITQDMLRRGVNVGFSGGEKKRNEILQMA
LLEPKLCILDETDSGLDIDALKVVAQGVNALRSPDRAMLVITHYQRLLDHIVPDVVHVMHKGRIVRSGGAELALELEESG
YAAYGQDAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=219, Percent_Identity=28.7671232876712, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI171184400, Length=244, Percent_Identity=31.5573770491803, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI42741659, Length=238, Percent_Identity=31.0924369747899, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787972, Length=242, Percent_Identity=61.5702479338843, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI87081709, Length=237, Percent_Identity=25.7383966244726, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI2367384, Length=232, Percent_Identity=26.7241379310345, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790525, Length=218, Percent_Identity=32.5688073394495, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787500, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994883, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786654, Length=230, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=241, Percent_Identity=25.3112033195021, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=239, Percent_Identity=27.1966527196653, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1789963, Length=249, Percent_Identity=28.1124497991968, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=233, Percent_Identity=27.4678111587983, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533592, Length=220, Percent_Identity=27.7272727272727, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=219, Percent_Identity=28.7671232876712, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=230, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI281363262, Length=219, Percent_Identity=28.7671232876712, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=28.7671232876712, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26886; Mature: 26886

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKNLHARIGDNEILKGLTLTVPAGEVHAIMGPNGSGKSTLSYVLSGKPDYEVTEGTA
CCCCCCHHHHCCCCHHHCCEEEEECCCCEEEEECCCCCCCHHHHHEECCCCCCEEECCEE
TFNGQDILSLAPEERAAAGVFLAFQYPIEIPGVANMQFLRAAMNAQKKARGEEEISTPDF
EECCCHHEEECCCHHHHCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
LKLVRAKAPDLGITQDMLRRGVNVGFSGGEKKRNEILQMALLEPKLCILDETDSGLDIDA
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
LKVVAQGVNALRSPDRAMLVITHYQRLLDHIVPDVVHVMHKGRIVRSGGAELALELEESG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCC
YAAYGQDAA
CCCCCCCCC
>Mature Secondary Structure
MLEIKNLHARIGDNEILKGLTLTVPAGEVHAIMGPNGSGKSTLSYVLSGKPDYEVTEGTA
CCCCCCHHHHCCCCHHHCCEEEEECCCCEEEEECCCCCCCHHHHHEECCCCCCEEECCEE
TFNGQDILSLAPEERAAAGVFLAFQYPIEIPGVANMQFLRAAMNAQKKARGEEEISTPDF
EECCCHHEEECCCHHHHCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
LKLVRAKAPDLGITQDMLRRGVNVGFSGGEKKRNEILQMALLEPKLCILDETDSGLDIDA
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
LKVVAQGVNALRSPDRAMLVITHYQRLLDHIVPDVVHVMHKGRIVRSGGAELALELEESG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCC
YAAYGQDAA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]