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The map label for this gene is lipB [H]

Identifier: 154248309

GI number: 154248309

Start: 4866208

End: 4867017

Strand: Direct

Name: lipB [H]

Synonym: Xaut_4389

Alternate gene names: 154248309

Gene position: 4866208-4867017 (Clockwise)

Preceding gene: 154248307

Following gene: 154248311

Centisome position: 91.66

GC content: 65.43

Gene sequence:

>810_bases
ATGCCTTTGCCCAGCGAAACCGGCGCAAGCCTCACCTTCACCATCCTGGGATGCGGGTCGTCCGGCGGCGTGCCACGGGT
GGGGCAGGGGTGGGGCGCCTGCGATCCCCTCAACCCCCGCAATCGCCGCCGCCGCTGCTCCATGCTCGTGGAGCGCGTCG
GGCCGAACGGGAAAACCACTGTGCTTGTGGACACTTCGCCAGACTTGCGGGAGCAGCTCATCGGCGAGGGCGTGACCCAT
ATCGACGCCGTGCTCTACACCCACGAGCACGCCGACCACACCCACGGCATAGACGACCTGCGCCCGCTGGCCATCCACAA
TCGCGCACGGGTGGACATATATGCGGACGAAGATACCTCCCGCATGCTGCATCAGCGCTTCGGCTACTGCTTTTCGACGC
CGCCCGGCAGCGCCTATCCGCCCATCCTTACCGAACATCGTTTCCGGGAGGGGCGGGAGATCGTGGTGGACGGGGCAGTC
GGCTTCCGCTTCGGCGACGTGGCCTATTCCAGCGACGTCAACGGGATCTCGGAGAACAGCCTGGCCCATCTTCACAATCT
GGATGTGTGGGTCATCGACGCCCTGCGCGAGACGCCCCATCCGTCGCACTTCACCCTTCAGGAGGCGCTGGACCATGTGG
CGCTCATGAAGCCGAAGCGCACGATCCTCACGAACCTCCACACCGATCTCGACTATGCCGCGCTGGAAGCACGCCTGCCC
GACGGCATCGTGCCGGCCTATGACGGCCTGAAATTCGAATCCCACAGCTGCTCGCACGCCGCATCCGCCGATACCGTTGC
GAGCGGCTGA

Upstream 100 bases:

>100_bases
GGGCCCTCGGGTGTGACTCCGGGACGAATTTGGATCAGGCTGCGGGCCGATTCCGCCCTGATCCCTGACCCGAGCAGCAG
ACGCAGCGAGGTCGCCAGTC

Downstream 100 bases:

>100_bases
CACGGCGGATAACCCGCGCCCCATGACCCTGATGTGGCGCCTCAAGCGATTCGCTCGATAGATTCAGATGCTGATGCAAA
GCATTGTTTAAAAACGATAT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MPLPSETGASLTFTILGCGSSGGVPRVGQGWGACDPLNPRNRRRRCSMLVERVGPNGKTTVLVDTSPDLREQLIGEGVTH
IDAVLYTHEHADHTHGIDDLRPLAIHNRARVDIYADEDTSRMLHQRFGYCFSTPPGSAYPPILTEHRFREGREIVVDGAV
GFRFGDVAYSSDVNGISENSLAHLHNLDVWVIDALRETPHPSHFTLQEALDHVALMKPKRTILTNLHTDLDYAALEARLP
DGIVPAYDGLKFESHSCSHAASADTVASG

Sequences:

>Translated_269_residues
MPLPSETGASLTFTILGCGSSGGVPRVGQGWGACDPLNPRNRRRRCSMLVERVGPNGKTTVLVDTSPDLREQLIGEGVTH
IDAVLYTHEHADHTHGIDDLRPLAIHNRARVDIYADEDTSRMLHQRFGYCFSTPPGSAYPPILTEHRFREGREIVVDGAV
GFRFGDVAYSSDVNGISENSLAHLHNLDVWVIDALRETPHPSHFTLQEALDHVALMKPKRTILTNLHTDLDYAALEARLP
DGIVPAYDGLKFESHSCSHAASADTVASG
>Mature_268_residues
PLPSETGASLTFTILGCGSSGGVPRVGQGWGACDPLNPRNRRRRCSMLVERVGPNGKTTVLVDTSPDLREQLIGEGVTHI
DAVLYTHEHADHTHGIDDLRPLAIHNRARVDIYADEDTSRMLHQRFGYCFSTPPGSAYPPILTEHRFREGREIVVDGAVG
FRFGDVAYSSDVNGISENSLAHLHNLDVWVIDALRETPHPSHFTLQEALDHVALMKPKRTILTNLHTDLDYAALEARLPD
GIVPAYDGLKFESHSCSHAASADTVASG

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29416; Mature: 29285

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPSETGASLTFTILGCGSSGGVPRVGQGWGACDPLNPRNRRRRCSMLVERVGPNGKTT
CCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VLVDTSPDLREQLIGEGVTHIDAVLYTHEHADHTHGIDDLRPLAIHNRARVDIYADEDTS
EEEECCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHEECCCEEEEEEECCHHH
RMLHQRFGYCFSTPPGSAYPPILTEHRFREGREIVVDGAVGFRFGDVAYSSDVNGISENS
HHHHHHCCCEECCCCCCCCCCCHHHHHHCCCCEEEEECCCCEEECCEEECCCCCCCCCCC
LAHLHNLDVWVIDALRETPHPSHFTLQEALDHVALMKPKRTILTNLHTDLDYAALEARLP
HHHHHCCCCEEEEHHHCCCCCCCEEHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCC
DGIVPAYDGLKFESHSCSHAASADTVASG
CCCCCCCCCCEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLPSETGASLTFTILGCGSSGGVPRVGQGWGACDPLNPRNRRRRCSMLVERVGPNGKTT
CCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VLVDTSPDLREQLIGEGVTHIDAVLYTHEHADHTHGIDDLRPLAIHNRARVDIYADEDTS
EEEECCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHEECCCEEEEEEECCHHH
RMLHQRFGYCFSTPPGSAYPPILTEHRFREGREIVVDGAVGFRFGDVAYSSDVNGISENS
HHHHHHCCCEECCCCCCCCCCCHHHHHHCCCCEEEEECCCCEEECCEEECCCCCCCCCCC
LAHLHNLDVWVIDALRETPHPSHFTLQEALDHVALMKPKRTILTNLHTDLDYAALEARLP
HHHHHCCCCEEEEHHHCCCCCCCEEHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCC
DGIVPAYDGLKFESHSCSHAASADTVASG
CCCCCCCCCCEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]