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The map label for this gene is ppiD [H]

Identifier: 154248299

GI number: 154248299

Start: 4854951

End: 4856843

Strand: Reverse

Name: ppiD [H]

Synonym: Xaut_4379

Alternate gene names: 154248299

Gene position: 4856843-4854951 (Counterclockwise)

Preceding gene: 154248301

Following gene: 154248298

Centisome position: 91.48

GC content: 69.78

Gene sequence:

>1893_bases
ATGGTACTTCAGACCCTTCGTAAGGGCGCGTCCGGCTGGATCGCCAAGATCTTCCTCGTCATCCTCACGCTCAGCTTCCT
GGTGTGGGGCATCGCGGACGTGTTCCGCGGCATGGGCGCGACCTCGGTGGCGAGCGTCGGCGCAACCGAAATTTCCGCCG
ATGCGTTCCGTCGTCAGTATCTCGATCAGCTCCAGCAGATCAGCCGCCGTGCCGGCCGTCCGATCTCGCCGGACCAGGCC
CGCGCCTTCGGCCTCGACCGGCAGATCCTGAACCAGATGATCGCCGACGCCACGCTGGACGAGCAGGCCTCCCGCCTCGC
CCTCGCCGTGTCCGACGAGCAGATCGCGCGCGAGATCGCCGACAATCCCAATTACCGCCGTCCCGGCGCCACCAGCTTCG
ATCCGGCCTATTTCCAGCAGCTGCTGCGATCCAACAACCTCACCGAGCAGCGCTTCGTCGCCTCCGAGCGCCAGCGCGCC
GTGCGCGACCAGCTGCTGAAGTCGCTGGGCGCTGGTGTCGCGGTGCCGCAGGTGCTCATCGATGCGGTGGGCCGCTTCGA
GAACGAGACCCGCACCGCCTCCTACGTGCGTGTCACCCCGGCCGCCGCCGGTCCCCTCGCCGCCCCCACGGACGAGGTGC
TGCGCGCCTATTTCGACGCCCACAAGGTCACCTTCCGCGCGCCGGAATACCGCAAGATCAGTGTCCTGGCGCTGACCCCG
GCGACGCTCGCCGCCGCCGAGACCGTGACGGAGGCCGACGCCAAGGCTGACTACGAGCGCAACCTTTCCCGCTTCGGCAC
GCCGGAGCGCCGGGAGGTGCAGCAGATCGTCTTCACCTCCGCCGCCGATGCCCTGGCCGCCGACGAGAAGATCAAGGCCG
GCGCGAGCTTCGCCGACATCGCCGCCGCCCGCGGCCTGACCGCCAAGGACACCGACCTCGGCCTCGTGGCGAAGTCCGCC
ATCCTCGATCCGAAGATCGCCGACGCCGCCTTCTCCATGCCCGAGGGCGCGGTGAGCGCGGTGGAGGGCCGCTTCGGCAC
GGTGCTGGTGCATGTCACCAAGGTCGAGCCCGGCGCCCGCCAGCCGTTCGAGGCAGTGAAGGACCAGATCAGCGCCGACC
TGCGCCTCGATCGCGCCCGCCGGGCGCTGCTCGACAAGCACGACCAGGTGGAGGACGAGCGCGCCTCCGGCTCGACCCTT
GCCGAGGTGGCGCAGAAGCTCGGCCTCAGGCTCCAGACCTTCGACGCGGTGGACCGCTCCGGCCACACCCCGTCGGGTGA
CCCGGCCGACGTGCCCGGCGGCGCGGACGTGCTGTCCGGCGCCTTCGCCGCCCAGCCGGGTGTGGAGACCGACACCGTCC
AGCTGCCGCAGAACGGCGGTTTCGTCTGGTACGAGACCAATGCCATCACCCCGGCCCGCGATCGCACCTTCGATGAGGCC
AAGTCCGCCGTCACCGCCCGCTGGACCGAATCCGAGACCGAGAAGGCAGTGGAAGCCAAGGCCACCGCCCTGCTCGACAA
GGCCAAGGCCGGCACCCCGCTGGCCCAGGTGGCCGCGGAGGCCGACCTGCCGCTCCAGATCGCCGAAGGCCTGCGCCGGG
GCCGGGCCGCCGGGCCGTTCAGCGCCGAGAGCATCGCCAGCGTGTTCGACGTAAAGGAAGGCGGCTTCGGCATTGCGCTC
GCCGCCACCGAGCCGGACCGCGTCGTCTTCGAGGTGACCAAGATCATGGTGCCGCCGCCGGACATGGACACCTCGCGCGC
CTCCGCAGAGCTGTCGCGCCAGATCGAGAATGACGTGTTGCTGCAGTATCTTTCCGCCATCCAGAAGGAGATCGGCGTGA
AGATCAACGACAAGCTCTTCGCCCAGGCCACGGGCGCTGGCGCGACCAACTGA

Upstream 100 bases:

>100_bases
CGGCCAAAAGGCATCAAGATGCGCCGTTGCGGGAGCAGGATGGCCTCACTATCATGCGCCGCTTCGCGCCGGACCCGGCC
AAAACGAGAACGAACCGTCG

Downstream 100 bases:

>100_bases
AGGTGGGCCACAGCGTGAACGCACCCACCGATTTCGACCTCTTCACCTCGCGCTACCTGAAGGGCGAGGCGCAGGTGGTT
TCCACCACCCTGGTGGCCGA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MVLQTLRKGASGWIAKIFLVILTLSFLVWGIADVFRGMGATSVASVGATEISADAFRRQYLDQLQQISRRAGRPISPDQA
RAFGLDRQILNQMIADATLDEQASRLALAVSDEQIAREIADNPNYRRPGATSFDPAYFQQLLRSNNLTEQRFVASERQRA
VRDQLLKSLGAGVAVPQVLIDAVGRFENETRTASYVRVTPAAAGPLAAPTDEVLRAYFDAHKVTFRAPEYRKISVLALTP
ATLAAAETVTEADAKADYERNLSRFGTPERREVQQIVFTSAADALAADEKIKAGASFADIAAARGLTAKDTDLGLVAKSA
ILDPKIADAAFSMPEGAVSAVEGRFGTVLVHVTKVEPGARQPFEAVKDQISADLRLDRARRALLDKHDQVEDERASGSTL
AEVAQKLGLRLQTFDAVDRSGHTPSGDPADVPGGADVLSGAFAAQPGVETDTVQLPQNGGFVWYETNAITPARDRTFDEA
KSAVTARWTESETEKAVEAKATALLDKAKAGTPLAQVAAEADLPLQIAEGLRRGRAAGPFSAESIASVFDVKEGGFGIAL
AATEPDRVVFEVTKIMVPPPDMDTSRASAELSRQIENDVLLQYLSAIQKEIGVKINDKLFAQATGAGATN

Sequences:

>Translated_630_residues
MVLQTLRKGASGWIAKIFLVILTLSFLVWGIADVFRGMGATSVASVGATEISADAFRRQYLDQLQQISRRAGRPISPDQA
RAFGLDRQILNQMIADATLDEQASRLALAVSDEQIAREIADNPNYRRPGATSFDPAYFQQLLRSNNLTEQRFVASERQRA
VRDQLLKSLGAGVAVPQVLIDAVGRFENETRTASYVRVTPAAAGPLAAPTDEVLRAYFDAHKVTFRAPEYRKISVLALTP
ATLAAAETVTEADAKADYERNLSRFGTPERREVQQIVFTSAADALAADEKIKAGASFADIAAARGLTAKDTDLGLVAKSA
ILDPKIADAAFSMPEGAVSAVEGRFGTVLVHVTKVEPGARQPFEAVKDQISADLRLDRARRALLDKHDQVEDERASGSTL
AEVAQKLGLRLQTFDAVDRSGHTPSGDPADVPGGADVLSGAFAAQPGVETDTVQLPQNGGFVWYETNAITPARDRTFDEA
KSAVTARWTESETEKAVEAKATALLDKAKAGTPLAQVAAEADLPLQIAEGLRRGRAAGPFSAESIASVFDVKEGGFGIAL
AATEPDRVVFEVTKIMVPPPDMDTSRASAELSRQIENDVLLQYLSAIQKEIGVKINDKLFAQATGAGATN
>Mature_630_residues
MVLQTLRKGASGWIAKIFLVILTLSFLVWGIADVFRGMGATSVASVGATEISADAFRRQYLDQLQQISRRAGRPISPDQA
RAFGLDRQILNQMIADATLDEQASRLALAVSDEQIAREIADNPNYRRPGATSFDPAYFQQLLRSNNLTEQRFVASERQRA
VRDQLLKSLGAGVAVPQVLIDAVGRFENETRTASYVRVTPAAAGPLAAPTDEVLRAYFDAHKVTFRAPEYRKISVLALTP
ATLAAAETVTEADAKADYERNLSRFGTPERREVQQIVFTSAADALAADEKIKAGASFADIAAARGLTAKDTDLGLVAKSA
ILDPKIADAAFSMPEGAVSAVEGRFGTVLVHVTKVEPGARQPFEAVKDQISADLRLDRARRALLDKHDQVEDERASGSTL
AEVAQKLGLRLQTFDAVDRSGHTPSGDPADVPGGADVLSGAFAAQPGVETDTVQLPQNGGFVWYETNAITPARDRTFDEA
KSAVTARWTESETEKAVEAKATALLDKAKAGTPLAQVAAEADLPLQIAEGLRRGRAAGPFSAESIASVFDVKEGGFGIAL
AATEPDRVVFEVTKIMVPPPDMDTSRASAELSRQIENDVLLQYLSAIQKEIGVKINDKLFAQATGAGATN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=528, Percent_Identity=21.4015151515152, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67459; Mature: 67459

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLQTLRKGASGWIAKIFLVILTLSFLVWGIADVFRGMGATSVASVGATEISADAFRRQY
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHH
LDQLQQISRRAGRPISPDQARAFGLDRQILNQMIADATLDEQASRLALAVSDEQIAREIA
HHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHH
DNPNYRRPGATSFDPAYFQQLLRSNNLTEQRFVASERQRAVRDQLLKSLGAGVAVPQVLI
CCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DAVGRFENETRTASYVRVTPAAAGPLAAPTDEVLRAYFDAHKVTFRAPEYRKISVLALTP
HHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEEECC
ATLAAAETVTEADAKADYERNLSRFGTPERREVQQIVFTSAADALAADEKIKAGASFADI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAARGLTAKDTDLGLVAKSAILDPKIADAAFSMPEGAVSAVEGRFGTVLVHVTKVEPGAR
HHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCCC
QPFEAVKDQISADLRLDRARRALLDKHDQVEDERASGSTLAEVAQKLGLRLQTFDAVDRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEHHHHHCC
GHTPSGDPADVPGGADVLSGAFAAQPGVETDTVQLPQNGGFVWYETNAITPARDRTFDEA
CCCCCCCCCCCCCCHHHHHCHHHCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCHHHH
KSAVTARWTESETEKAVEAKATALLDKAKAGTPLAQVAAEADLPLQIAEGLRRGRAAGPF
HHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCC
SAESIASVFDVKEGGFGIALAATEPDRVVFEVTKIMVPPPDMDTSRASAELSRQIENDVL
CHHHHHHHHHCCCCCCEEEEECCCCCHHHEEEHHHEECCCCCCCHHHHHHHHHHHHHHHH
LQYLSAIQKEIGVKINDKLFAQATGAGATN
HHHHHHHHHHHCCCCCCHHHEEECCCCCCC
>Mature Secondary Structure
MVLQTLRKGASGWIAKIFLVILTLSFLVWGIADVFRGMGATSVASVGATEISADAFRRQY
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHH
LDQLQQISRRAGRPISPDQARAFGLDRQILNQMIADATLDEQASRLALAVSDEQIAREIA
HHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHH
DNPNYRRPGATSFDPAYFQQLLRSNNLTEQRFVASERQRAVRDQLLKSLGAGVAVPQVLI
CCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DAVGRFENETRTASYVRVTPAAAGPLAAPTDEVLRAYFDAHKVTFRAPEYRKISVLALTP
HHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEEECC
ATLAAAETVTEADAKADYERNLSRFGTPERREVQQIVFTSAADALAADEKIKAGASFADI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AAARGLTAKDTDLGLVAKSAILDPKIADAAFSMPEGAVSAVEGRFGTVLVHVTKVEPGAR
HHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCCC
QPFEAVKDQISADLRLDRARRALLDKHDQVEDERASGSTLAEVAQKLGLRLQTFDAVDRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEHHHHHCC
GHTPSGDPADVPGGADVLSGAFAAQPGVETDTVQLPQNGGFVWYETNAITPARDRTFDEA
CCCCCCCCCCCCCCHHHHHCHHHCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCHHHH
KSAVTARWTESETEKAVEAKATALLDKAKAGTPLAQVAAEADLPLQIAEGLRRGRAAGPF
HHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCC
SAESIASVFDVKEGGFGIALAATEPDRVVFEVTKIMVPPPDMDTSRASAELSRQIENDVL
CHHHHHHHHHCCCCCCEEEEECCCCCHHHEEEHHHEECCCCCCCHHHHHHHHHHHHHHHH
LQYLSAIQKEIGVKINDKLFAQATGAGATN
HHHHHHHHHHHCCCCCCHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]