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The map label for this gene is queF [H]

Identifier: 154248208

GI number: 154248208

Start: 4755818

End: 4756270

Strand: Reverse

Name: queF [H]

Synonym: Xaut_4288

Alternate gene names: 154248208

Gene position: 4756270-4755818 (Counterclockwise)

Preceding gene: 154248210

Following gene: 154248207

Centisome position: 89.59

GC content: 66.67

Gene sequence:

>453_bases
ATGACCGATCGCCCGCTGCAGCTCGGCGTCAGCGCCGCCCTGCCCGCCTCGCCGGAGGAGGCGGTGCTCGACCGCGTGCC
AAACCCGCATCCGGACGTGGATTATGTGGCGCGCTTCACCTGCCCGGAATTCACCTCGCTCTGCCCGGTGACGGGACAGC
CGGATTTCGCTCACATCGTGATCGACTATGTGCCGGACCAGTTCCTGGTGGAGTCCAAGTCGCTGAAGCTGTACCTCGGC
AGCTTCCGCAATCATGGCGCGTTCCACGAGGATTGCACCGTGGCGGTGGGCAAGCGGCTGGTGGACTTGCTCAAGCCGCG
CTTCCTGCGCATCGCCGGATACTGGTATCCGCGCGGCGGCATCCCCATCGACGTGTTCTGGCAGACCGGAAAGCTGGCCG
AGGGCGTGTGGTTGCCGGATACGGGGGTTGCGCCCTACCGCGGTCGCGGGTGA

Upstream 100 bases:

>100_bases
GCGTTCCAGGCGGGCTTCGCCGCAAAACGGCCGGACGGCGGTTGAACATTATGGCCCGCGCGGGTAGAGCACCCGCTCTT
CCGCCGCAGGATCAAGAGAT

Downstream 100 bases:

>100_bases
AGCTGTCGACTCCGGAGCCGCCGACGCCAGAAAAACCTGAGCGGCCCGGGGGAGGACGGAGGGCACGGGTTATGCCGAAG
CTCATTGTCACCAATGGAGA

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTDRPLQLGVSAALPASPEEAVLDRVPNPHPDVDYVARFTCPEFTSLCPVTGQPDFAHIVIDYVPDQFLVESKSLKLYLG
SFRNHGAFHEDCTVAVGKRLVDLLKPRFLRIAGYWYPRGGIPIDVFWQTGKLAEGVWLPDTGVAPYRGRG

Sequences:

>Translated_150_residues
MTDRPLQLGVSAALPASPEEAVLDRVPNPHPDVDYVARFTCPEFTSLCPVTGQPDFAHIVIDYVPDQFLVESKSLKLYLG
SFRNHGAFHEDCTVAVGKRLVDLLKPRFLRIAGYWYPRGGIPIDVFWQTGKLAEGVWLPDTGVAPYRGRG
>Mature_149_residues
TDRPLQLGVSAALPASPEEAVLDRVPNPHPDVDYVARFTCPEFTSLCPVTGQPDFAHIVIDYVPDQFLVESKSLKLYLGS
FRNHGAFHEDCTVAVGKRLVDLLKPRFLRIAGYWYPRGGIPIDVFWQTGKLAEGVWLPDTGVAPYRGRG

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 16667; Mature: 16536

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRPLQLGVSAALPASPEEAVLDRVPNPHPDVDYVARFTCPEFTSLCPVTGQPDFAHIV
CCCCCCEECCEECCCCCCHHHHHHCCCCCCCCHHHEEEECCCCCCCCCCCCCCCCEEEEE
IDYVPDQFLVESKSLKLYLGSFRNHGAFHEDCTVAVGKRLVDLLKPRFLRIAGYWYPRGG
EEECCCCEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
IPIDVFWQTGKLAEGVWLPDTGVAPYRGRG
CEEEEEEECCCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
TDRPLQLGVSAALPASPEEAVLDRVPNPHPDVDYVARFTCPEFTSLCPVTGQPDFAHIV
CCCCCEECCEECCCCCCHHHHHHCCCCCCCCHHHEEEECCCCCCCCCCCCCCCCEEEEE
IDYVPDQFLVESKSLKLYLGSFRNHGAFHEDCTVAVGKRLVDLLKPRFLRIAGYWYPRGG
EEECCCCEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
IPIDVFWQTGKLAEGVWLPDTGVAPYRGRG
CEEEEEEECCCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA