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The map label for this gene is thiL [H]

Identifier: 154248202

GI number: 154248202

Start: 4747635

End: 4748645

Strand: Direct

Name: thiL [H]

Synonym: Xaut_4282

Alternate gene names: 154248202

Gene position: 4747635-4748645 (Clockwise)

Preceding gene: 154248201

Following gene: 154248204

Centisome position: 89.43

GC content: 72.3

Gene sequence:

>1011_bases
ATGGCGGAAGGCGGCGACGGGGCAGGGGGATCGGGCGAGGATCGCTTCATCGCGCGCTTCCTGCGTCCCATCGCCGGTTC
GTCCGCCGCCCTGGGCCTGCTCGACGATGCCGCACTGCTGACCCCGCCCGAGGGCTGCGACCTGGTTCTCACCAAGGACG
CCGTGGTGGCAGGGGTCCATTTCTTCGCCGACGATCCGCCCGCCTCCATCGCCCGCAAGGCGCTGCGGGTGAACCTCTCC
GACCTTGCCGCCAAGGGCGCCGACCCGCTCGGCGCCCTGCTGGCGCTGGCCCTGCCCAAGGGCACGCCAGACGCCTGGAT
GGAAGCCTTCGCCGCCGCGCTGGGCGAGGATACGGAGCGCTATCTGTGCCCCATTCTCGGCGGCGATACAGTCTCCATCC
CCGGTCCGGTCACCATCACGCTCACCGCTTTGGGCTCGGTGCCGAAGGGGGCCTTCGTGCCTCGCACGGGGGCCAGGCCC
GGCCAGGCCATCCTCGTCACCGGCACCATCGGCGATGCCGCGCTGGGCCTGCGGCTTCGGCAGGACGGCAAGGCTGCGGC
CTTCGCCGGCCTCAGCGACGAGCAGCGCGGCCATCTGCTGGACCGCTATCTGCACCCCCAGCCCCGTCTCGCCATCGCAC
CGGTGCTGCGCCGCTACGCCAAGTCCGCCATGGATGTGTCCGACGGGCTTGCCGGCGACGTGGCGAAGATGCTCGCCGCT
TCGGGCTGCGGCGGGCGCATCGAGGCGCGGCGGGTGCCGGTGTCGGCCGCCGCTGCGGAGGCCATCGCAGCCGACGCCGG
CCTGTTCAGGACCGCGATCACTGGCGGGGACGATTACGAGGTGGTGGCCTGCGTGCCCCATGCCCTGGTCCACGTCTTCA
CCGCCGAGGCGGCGCGGGTGGGCGTACCGGTGACGCTGATCGGCGAGACGCGGGAGCAGCCCGGCCTTGATGTGACCGAT
GCCGGCGGCCATCCCCTCGACCTCGGCGCCGGCAGCTTCAGCCACTTCTGA

Upstream 100 bases:

>100_bases
GCCGGCGCCTTCCTCGATCGCGACGAGACCGGCATGGTCAACGCCGTGCTGGACGCTCTGGCCCACGACCTGCGCCCCGA
CGAGTTCAAGGGCGGCTGAC

Downstream 100 bases:

>100_bases
GCCGGCGGGTCCGCGGCGCTATCCTAGCGCCACCAGCGCCGCCCCGGCGGCGATGAGGACCACGCCGAGGGTCGCCAGCG
CGCTCAGGCGCTCGCCCAGG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAEGGDGAGGSGEDRFIARFLRPIAGSSAALGLLDDAALLTPPEGCDLVLTKDAVVAGVHFFADDPPASIARKALRVNLS
DLAAKGADPLGALLALALPKGTPDAWMEAFAAALGEDTERYLCPILGGDTVSIPGPVTITLTALGSVPKGAFVPRTGARP
GQAILVTGTIGDAALGLRLRQDGKAAAFAGLSDEQRGHLLDRYLHPQPRLAIAPVLRRYAKSAMDVSDGLAGDVAKMLAA
SGCGGRIEARRVPVSAAAAEAIAADAGLFRTAITGGDDYEVVACVPHALVHVFTAEAARVGVPVTLIGETREQPGLDVTD
AGGHPLDLGAGSFSHF

Sequences:

>Translated_336_residues
MAEGGDGAGGSGEDRFIARFLRPIAGSSAALGLLDDAALLTPPEGCDLVLTKDAVVAGVHFFADDPPASIARKALRVNLS
DLAAKGADPLGALLALALPKGTPDAWMEAFAAALGEDTERYLCPILGGDTVSIPGPVTITLTALGSVPKGAFVPRTGARP
GQAILVTGTIGDAALGLRLRQDGKAAAFAGLSDEQRGHLLDRYLHPQPRLAIAPVLRRYAKSAMDVSDGLAGDVAKMLAA
SGCGGRIEARRVPVSAAAAEAIAADAGLFRTAITGGDDYEVVACVPHALVHVFTAEAARVGVPVTLIGETREQPGLDVTD
AGGHPLDLGAGSFSHF
>Mature_335_residues
AEGGDGAGGSGEDRFIARFLRPIAGSSAALGLLDDAALLTPPEGCDLVLTKDAVVAGVHFFADDPPASIARKALRVNLSD
LAAKGADPLGALLALALPKGTPDAWMEAFAAALGEDTERYLCPILGGDTVSIPGPVTITLTALGSVPKGAFVPRTGARPG
QAILVTGTIGDAALGLRLRQDGKAAAFAGLSDEQRGHLLDRYLHPQPRLAIAPVLRRYAKSAMDVSDGLAGDVAKMLAAS
GCGGRIEARRVPVSAAAAEAIAADAGLFRTAITGGDDYEVVACVPHALVHVFTAEAARVGVPVTLIGETREQPGLDVTDA
GGHPLDLGAGSFSHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=40.5487804878049, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34103; Mature: 33972

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGGDGAGGSGEDRFIARFLRPIAGSSAALGLLDDAALLTPPEGCDLVLTKDAVVAGVH
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCEEEECCHHEEEEE
FFADDPPASIARKALRVNLSDLAAKGADPLGALLALALPKGTPDAWMEAFAAALGEDTER
EECCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
YLCPILGGDTVSIPGPVTITLTALGSVPKGAFVPRTGARPGQAILVTGTIGDAALGLRLR
EEEEEECCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHCEEEC
QDGKAAAFAGLSDEQRGHLLDRYLHPQPRLAIAPVLRRYAKSAMDVSDGLAGDVAKMLAA
CCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SGCGGRIEARRVPVSAAAAEAIAADAGLFRTAITGGDDYEVVACVPHALVHVFTAEAARV
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHC
GVPVTLIGETREQPGLDVTDAGGHPLDLGAGSFSHF
CCCEEEEECCCCCCCCCEECCCCCEEECCCCCCCCC
>Mature Secondary Structure 
AEGGDGAGGSGEDRFIARFLRPIAGSSAALGLLDDAALLTPPEGCDLVLTKDAVVAGVH
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCEEEECCHHEEEEE
FFADDPPASIARKALRVNLSDLAAKGADPLGALLALALPKGTPDAWMEAFAAALGEDTER
EECCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
YLCPILGGDTVSIPGPVTITLTALGSVPKGAFVPRTGARPGQAILVTGTIGDAALGLRLR
EEEEEECCCEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHCEEEC
QDGKAAAFAGLSDEQRGHLLDRYLHPQPRLAIAPVLRRYAKSAMDVSDGLAGDVAKMLAA
CCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SGCGGRIEARRVPVSAAAAEAIAADAGLFRTAITGGDDYEVVACVPHALVHVFTAEAARV
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHC
GVPVTLIGETREQPGLDVTDAGGHPLDLGAGSFSHF
CCCEEEEECCCCCCCCCEECCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]