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The map label for this gene is ychM [C]

Identifier: 154248090

GI number: 154248090

Start: 4617206

End: 4618816

Strand: Reverse

Name: ychM [C]

Synonym: Xaut_4170

Alternate gene names: 154248090

Gene position: 4618816-4617206 (Counterclockwise)

Preceding gene: 154248091

Following gene: 154248082

Centisome position: 87.0

GC content: 71.94

Gene sequence:

>1611_bases
ATGTCATCGATCCCAGGGCCACGGGCCGGCGATTTCATCGCCGGCCTCTGCCTCGCCGGCCTTTTGCTGCCGGAAGCGGT
GGCCTATGCGAGCATTGCCGGCCTGCCGCCGCAGCACGGCATCTTCGCCGCCGTCGCCGGATGCTTCGTCTACGGATTGG
CCGGGCGCAGCCGGTTCGCCATCGTCTCTCCGACCTCATCGTCCGCCGCGATCCTGGCCGCCACGCTGGCGACCCTGCCG
GACGAGGGCGCGGTAAAGCTCGCCGCGACCACGGTGGTGGTGGCGCTGGTCGGCGGCTTCCTGCTGCTGGCGGCCGTGGC
GCGGCTCGGAAACTTCACCGGGTTTGTCTCGCGGCCGGTGCTGCGCGGGTTCGCGTTCGGGCTGGCGGTGACCATCATCG
CCCGCCAGTTGCCACATCTCGTGGGCGTGGAGGCGGCATCGACGGACATCTTCCATCTCGTGCCGCAGCTCGTGCTGGAG
CTACCACGATGGAACCCGTTCGCCGTGGCGGCCGGCGGCATGGCGCTGGCGGTGTTGCTGGCGCTCCGGCGGTTCCCGGC
CATCCCCGGCGCCTTCGTCGTCCTTGCCGGCGGCGTGGCCGCCTCCACCGTGTTCGGGCTGGAGGGGCACGGGGTCTCCG
TGGTCGGCACCATCGACATCGTGCCGGCGTGGCCCTCCTGGCCAAGCCTCGGCTGGGCGGATTATTCCCAGCTCGCCCGC
TTCGCCCTGCCGCTCGTTCTGATCCTCTTCGCTGAATCCTGGGGCACGATCCGGGCGCTGTCGCTGCGCCATGGCGAGGC
GGTCGACGCGGATCGGGAGCTGGCCGCCATCGGCCTTGCCAACATGGCCAGTGCGCTGGCCCAGGGCATGCCCGTGGGCG
CCGGATTCTCGGCCGGCAACGCCAGCGAGGCCGCCGGAGCCGCCACCCGCGCCACCGCCTTCGTCACCGCGCTGGGCCTC
GCGATCCTCGTGATCTTCGGCGGGAGTTTCGTGGCGCGCCTGCCCGAGCCAGTGCTGGCGGCGGTGGTGATCGCGGCCCT
CGTCCATGCGCTGGATCCAGCGCCGCTCGCGCGCCTGTGGACGCTGGGGCGCGACCAGTATGTGGCCGTCGCCGCGGCCG
TGGCCGTGCTGGCGCTCGGCGTCCTGAACGGGATGCTGGTGGCCATCGCCCTGTCCCTCACCGCCGTGGTGCAGCGGCTG
GCGGCGCCCCAGGTGGCGCAGCTGGGACGGCTCGGCACGACGCACGATTATGTCGATCTTGCCCGCCATCCCGATGCCGT
CGCCCCGCAGGGCATCGCCATCTGGCGGCCGGCGCAGCCGCTGTTCTTCGCCAACGCCGACCGGATCATGGGCATCATCG
CCGCCAGCTCCCGCGCCGAGCCGGGCCTTCACGCGGTGGTGGTGAGCCTCGAGGAAAGCTTTGATCTGGACAGCACGGCC
CTCGACGCCCTGGTGGAGTTCGATGCCGTCATGCGCCAGGCTGGGCTGCGCCTGCAGCTCGCCCGCGCCCATGATCGTGT
CCGCGACCTGCTGGCGGCCGCCGGCGCCCGCGATCTGGTGGCGCGCTGCAGCTACAGCGTGGACGATGCGGTGGCCGCGG
TGCAGCCATAA

Upstream 100 bases:

>100_bases
GCTGGCGTACGCAGCCCGCTCTCGACGCGCTATGGTGGCCGACAGGATGGATGGGCGATCGGCGCACCGCAAGATCCGCC
GCACGTCGACAGGTGAGGCT

Downstream 100 bases:

>100_bases
CCCTCAGGGGCCCCACCCGCCACCCAGCGCCTGGAACAGGCTGGTGGCGGCCAGCAGCCGCGACAGCCGCGCCTGCGCCA
GGCCATTCTCGGCTGTAAAG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MSSIPGPRAGDFIAGLCLAGLLLPEAVAYASIAGLPPQHGIFAAVAGCFVYGLAGRSRFAIVSPTSSSAAILAATLATLP
DEGAVKLAATTVVVALVGGFLLLAAVARLGNFTGFVSRPVLRGFAFGLAVTIIARQLPHLVGVEAASTDIFHLVPQLVLE
LPRWNPFAVAAGGMALAVLLALRRFPAIPGAFVVLAGGVAASTVFGLEGHGVSVVGTIDIVPAWPSWPSLGWADYSQLAR
FALPLVLILFAESWGTIRALSLRHGEAVDADRELAAIGLANMASALAQGMPVGAGFSAGNASEAAGAATRATAFVTALGL
AILVIFGGSFVARLPEPVLAAVVIAALVHALDPAPLARLWTLGRDQYVAVAAAVAVLALGVLNGMLVAIALSLTAVVQRL
AAPQVAQLGRLGTTHDYVDLARHPDAVAPQGIAIWRPAQPLFFANADRIMGIIAASSRAEPGLHAVVVSLEESFDLDSTA
LDALVEFDAVMRQAGLRLQLARAHDRVRDLLAAAGARDLVARCSYSVDDAVAAVQP

Sequences:

>Translated_536_residues
MSSIPGPRAGDFIAGLCLAGLLLPEAVAYASIAGLPPQHGIFAAVAGCFVYGLAGRSRFAIVSPTSSSAAILAATLATLP
DEGAVKLAATTVVVALVGGFLLLAAVARLGNFTGFVSRPVLRGFAFGLAVTIIARQLPHLVGVEAASTDIFHLVPQLVLE
LPRWNPFAVAAGGMALAVLLALRRFPAIPGAFVVLAGGVAASTVFGLEGHGVSVVGTIDIVPAWPSWPSLGWADYSQLAR
FALPLVLILFAESWGTIRALSLRHGEAVDADRELAAIGLANMASALAQGMPVGAGFSAGNASEAAGAATRATAFVTALGL
AILVIFGGSFVARLPEPVLAAVVIAALVHALDPAPLARLWTLGRDQYVAVAAAVAVLALGVLNGMLVAIALSLTAVVQRL
AAPQVAQLGRLGTTHDYVDLARHPDAVAPQGIAIWRPAQPLFFANADRIMGIIAASSRAEPGLHAVVVSLEESFDLDSTA
LDALVEFDAVMRQAGLRLQLARAHDRVRDLLAAAGARDLVARCSYSVDDAVAAVQP
>Mature_535_residues
SSIPGPRAGDFIAGLCLAGLLLPEAVAYASIAGLPPQHGIFAAVAGCFVYGLAGRSRFAIVSPTSSSAAILAATLATLPD
EGAVKLAATTVVVALVGGFLLLAAVARLGNFTGFVSRPVLRGFAFGLAVTIIARQLPHLVGVEAASTDIFHLVPQLVLEL
PRWNPFAVAAGGMALAVLLALRRFPAIPGAFVVLAGGVAASTVFGLEGHGVSVVGTIDIVPAWPSWPSLGWADYSQLARF
ALPLVLILFAESWGTIRALSLRHGEAVDADRELAAIGLANMASALAQGMPVGAGFSAGNASEAAGAATRATAFVTALGLA
ILVIFGGSFVARLPEPVLAAVVIAALVHALDPAPLARLWTLGRDQYVAVAAAVAVLALGVLNGMLVAIALSLTAVVQRLA
APQVAQLGRLGTTHDYVDLARHPDAVAPQGIAIWRPAQPLFFANADRIMGIIAASSRAEPGLHAVVVSLEESFDLDSTAL
DALVEFDAVMRQAGLRLQLARAHDRVRDLLAAAGARDLVARCSYSVDDAVAAVQP

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721259, Length=457, Percent_Identity=28.6652078774617, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI94721255, Length=457, Percent_Identity=28.6652078774617, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI94721253, Length=457, Percent_Identity=28.6652078774617, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI94721257, Length=457, Percent_Identity=28.6652078774617, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI45827800, Length=476, Percent_Identity=25.6302521008403, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI39752683, Length=476, Percent_Identity=25.6302521008403, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI269784651, Length=474, Percent_Identity=24.2616033755274, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI47131207, Length=488, Percent_Identity=28.2786885245902, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI20336272, Length=488, Percent_Identity=28.2786885245902, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4557535, Length=483, Percent_Identity=25.0517598343685, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI45827802, Length=428, Percent_Identity=25.2336448598131, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4505697, Length=486, Percent_Identity=21.8106995884774, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI100913030, Length=492, Percent_Identity=22.5609756097561, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI262206105, Length=142, Percent_Identity=38.0281690140845, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI262206075, Length=142, Percent_Identity=38.0281690140845, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI262206069, Length=142, Percent_Identity=38.0281690140845, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI262206063, Length=142, Percent_Identity=38.0281690140845, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI16418413, Length=498, Percent_Identity=23.6947791164659, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI217272867, Length=498, Percent_Identity=24.0963855421687, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI65506789, Length=385, Percent_Identity=23.3766233766234, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081859, Length=549, Percent_Identity=24.0437158469945, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551690, Length=550, Percent_Identity=22.1818181818182, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17566848, Length=477, Percent_Identity=25.9958071278826, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17562578, Length=533, Percent_Identity=25.515947467167, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI86564876, Length=582, Percent_Identity=21.4776632302405, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI86564196, Length=485, Percent_Identity=22.8865979381443, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI86565215, Length=524, Percent_Identity=23.8549618320611, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI193203292, Length=557, Percent_Identity=22.6211849192101, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=584, Percent_Identity=21.9178082191781, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319771, Length=462, Percent_Identity=22.2943722943723, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922482, Length=423, Percent_Identity=26.0047281323877, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24663084, Length=471, Percent_Identity=24.416135881104, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357695, Length=471, Percent_Identity=24.416135881104, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24666186, Length=406, Percent_Identity=25.1231527093596, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358229, Length=144, Percent_Identity=34.0277777777778, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647160, Length=253, Percent_Identity=24.5059288537549, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355087, Length=253, Percent_Identity=24.5059288537549, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649801, Length=175, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651449, Length=136, Percent_Identity=30.1470588235294, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85815873, Length=144, Percent_Identity=31.9444444444444, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21358633, Length=134, Percent_Identity=32.089552238806, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 54864; Mature: 54732

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIPGPRAGDFIAGLCLAGLLLPEAVAYASIAGLPPQHGIFAAVAGCFVYGLAGRSRFA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEE
IVSPTSSSAAILAATLATLPDEGAVKLAATTVVVALVGGFLLLAAVARLGNFTGFVSRPV
EECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LRGFAFGLAVTIIARQLPHLVGVEAASTDIFHLVPQLVLELPRWNPFAVAAGGMALAVLL
HHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHH
ALRRFPAIPGAFVVLAGGVAASTVFGLEGHGVSVVGTIDIVPAWPSWPSLGWADYSQLAR
HHHHCCCCCCHHHHHCCCHHHHHEECCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHH
FALPLVLILFAESWGTIRALSLRHGEAVDADRELAAIGLANMASALAQGMPVGAGFSAGN
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ASEAAGAATRATAFVTALGLAILVIFGGSFVARLPEPVLAAVVIAALVHALDPAPLARLW
CCHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHH
TLGRDQYVAVAAAVAVLALGVLNGMLVAIALSLTAVVQRLAAPQVAQLGRLGTTHDYVDL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHH
ARHPDAVAPQGIAIWRPAQPLFFANADRIMGIIAASSRAEPGLHAVVVSLEESFDLDSTA
HCCCCCCCCCCEEEECCCCCCEECCHHHHHHHHEECCCCCCCCEEEEEEEHHCCCCCHHH
LDALVEFDAVMRQAGLRLQLARAHDRVRDLLAAAGARDLVARCSYSVDDAVAAVQP
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure 
SSIPGPRAGDFIAGLCLAGLLLPEAVAYASIAGLPPQHGIFAAVAGCFVYGLAGRSRFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEE
IVSPTSSSAAILAATLATLPDEGAVKLAATTVVVALVGGFLLLAAVARLGNFTGFVSRPV
EECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LRGFAFGLAVTIIARQLPHLVGVEAASTDIFHLVPQLVLELPRWNPFAVAAGGMALAVLL
HHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHH
ALRRFPAIPGAFVVLAGGVAASTVFGLEGHGVSVVGTIDIVPAWPSWPSLGWADYSQLAR
HHHHCCCCCCHHHHHCCCHHHHHEECCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHH
FALPLVLILFAESWGTIRALSLRHGEAVDADRELAAIGLANMASALAQGMPVGAGFSAGN
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ASEAAGAATRATAFVTALGLAILVIFGGSFVARLPEPVLAAVVIAALVHALDPAPLARLW
CCHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHH
TLGRDQYVAVAAAVAVLALGVLNGMLVAIALSLTAVVQRLAAPQVAQLGRLGTTHDYVDL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHH
ARHPDAVAPQGIAIWRPAQPLFFANADRIMGIIAASSRAEPGLHAVVVSLEESFDLDSTA
HCCCCCCCCCCEEEECCCCCCEECCHHHHHHHHEECCCCCCCCEEEEEEEHHCCCCCHHH
LDALVEFDAVMRQAGLRLQLARAHDRVRDLLAAAGARDLVARCSYSVDDAVAAVQP
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]