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The map label for this gene is aroC

Identifier: 154248059

GI number: 154248059

Start: 4579261

End: 4580373

Strand: Reverse

Name: aroC

Synonym: Xaut_4138

Alternate gene names: 154248059

Gene position: 4580373-4579261 (Counterclockwise)

Preceding gene: 154248061

Following gene: 154248058

Centisome position: 86.28

GC content: 69.99

Gene sequence:

>1113_bases
ATGTCGTTCAACACGTTCGGGCATCTGTTTCGGGTCACCACCTTCGGCGAAAGCCACGGGGCGGCCATCGGCTGCGTGGT
GGACGGCTGCCCGCCCAACCTGCGCTTCACCCTTGAGGATGTGCAGGCCGCCCTCGACCGGCGGCGGCCCGGCCAGTCGC
GCTTCACCACGCAGCGGCGCGAGCCGGACCAGGTGAAGGTGCTCTCCGGCACGCTGGAGCATCCCGAAGGCGGCCTCGTC
ACCACCGGCACGCCCATCGCGCTGCTGATCGAGAACGTGGACCAGCGCTCCAAGGATTATGCCGACATCGCCGGTGCCTA
CCGGCCGGGGCATGCGGATTTCACCTACGACATCAAGTACGGCATCCGCGACCATCGCGGCGGCGGGCGCTCCTCGGCGC
GGGAGACGGCGACGCGGGTCGCTGCCGGCGCCATCGCCGCCAAGGTTCTGCCGGGCGTCACCGTGCGCGGGGCCGTGGTG
CGCATCGGCGAGATCGAGATCGACCGCAGCCGCTGGGACTGGAACGAGGTCCCCAACAACCCGTTCTTCTGCCCCGACCC
CAAGACGGTGCCACTCTGGGAAGAGTATCTGGATGCAGTCCGCAAGGCCGGCTCCTCCATCGGCGCGGTGGTGGAACTGG
TGGCGGAAGGCGTTCCGGCGGGCCTCGGCGCGCCGCTCTACGGCAAGCTCGACGCCGACCTCGCCAGCGCCCTGCTCGGC
ATCAACGCGGCCAAGGGTGTGGAGATCGGCGAGGGCTTCAACGCCGCCCAGCTCACCGGCGAGGAGAATGCCGACGAGAT
GCGCCTCGGCAACGAGGGCCGTCCGCAATTCCTCTCCAACCATGCCGGCGGCATCCTCGGTGGCATCGCCACCGGGGCGC
CCATCGTGGCCCGGTTCGCGCTGAAGCCCACCTCCTCCATCCTCACCCCCCGCCAGACCGTGGACCGCACCGGCCAGGAG
ACGGAGATCTTCACCAAGGGCCGTCACGACCCCTGCGTCGGCATCCGCGCGGTGCCGGTGGGCGAGGCCATGATGTGGTG
CGTGCTCGCCGACCATTTCCTGCGCCACCGCGGGCAGGTGGGCGAAAGCGTGGCCTGGCCGTTCAAGGGGTGA

Upstream 100 bases:

>100_bases
AACTTGGGCCGGACGGTGGACGCCATGAACCGAGACTTGAGTTTCCTCTCGCGTGATCCTCGTTTATTGAGCCGGGACGA
GTGAGGGGTTTTGTCGCGTC

Downstream 100 bases:

>100_bases
GCGGCACCCTGTACTGAAGCATGACTGTATAGGCCTTCAGACAGGTAGTATTTTCGGGGCGTGGGAACGTAATGGGCGCC
CCTGCGTTCGGTCTGCATAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSFNTFGHLFRVTTFGESHGAAIGCVVDGCPPNLRFTLEDVQAALDRRRPGQSRFTTQRREPDQVKVLSGTLEHPEGGLV
TTGTPIALLIENVDQRSKDYADIAGAYRPGHADFTYDIKYGIRDHRGGGRSSARETATRVAAGAIAAKVLPGVTVRGAVV
RIGEIEIDRSRWDWNEVPNNPFFCPDPKTVPLWEEYLDAVRKAGSSIGAVVELVAEGVPAGLGAPLYGKLDADLASALLG
INAAKGVEIGEGFNAAQLTGEENADEMRLGNEGRPQFLSNHAGGILGGIATGAPIVARFALKPTSSILTPRQTVDRTGQE
TEIFTKGRHDPCVGIRAVPVGEAMMWCVLADHFLRHRGQVGESVAWPFKG

Sequences:

>Translated_370_residues
MSFNTFGHLFRVTTFGESHGAAIGCVVDGCPPNLRFTLEDVQAALDRRRPGQSRFTTQRREPDQVKVLSGTLEHPEGGLV
TTGTPIALLIENVDQRSKDYADIAGAYRPGHADFTYDIKYGIRDHRGGGRSSARETATRVAAGAIAAKVLPGVTVRGAVV
RIGEIEIDRSRWDWNEVPNNPFFCPDPKTVPLWEEYLDAVRKAGSSIGAVVELVAEGVPAGLGAPLYGKLDADLASALLG
INAAKGVEIGEGFNAAQLTGEENADEMRLGNEGRPQFLSNHAGGILGGIATGAPIVARFALKPTSSILTPRQTVDRTGQE
TEIFTKGRHDPCVGIRAVPVGEAMMWCVLADHFLRHRGQVGESVAWPFKG
>Mature_369_residues
SFNTFGHLFRVTTFGESHGAAIGCVVDGCPPNLRFTLEDVQAALDRRRPGQSRFTTQRREPDQVKVLSGTLEHPEGGLVT
TGTPIALLIENVDQRSKDYADIAGAYRPGHADFTYDIKYGIRDHRGGGRSSARETATRVAAGAIAAKVLPGVTVRGAVVR
IGEIEIDRSRWDWNEVPNNPFFCPDPKTVPLWEEYLDAVRKAGSSIGAVVELVAEGVPAGLGAPLYGKLDADLASALLGI
NAAKGVEIGEGFNAAQLTGEENADEMRLGNEGRPQFLSNHAGGILGGIATGAPIVARFALKPTSSILTPRQTVDRTGQET
EIFTKGRHDPCVGIRAVPVGEAMMWCVLADHFLRHRGQVGESVAWPFKG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=362, Percent_Identity=60.2209944751381, Blast_Score=417, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=43.4316353887399, Blast_Score=283, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_XANP2 (A7IMW7)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419017.1
- ProteinModelPortal:   A7IMW7
- SMR:   A7IMW7
- STRING:   A7IMW7
- GeneID:   5425283
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4138
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   XAUT78245:XAUT_4138-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39645; Mature: 39514

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNTFGHLFRVTTFGESHGAAIGCVVDGCPPNLRFTLEDVQAALDRRRPGQSRFTTQRR
CCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHCCCCC
EPDQVKVLSGTLEHPEGGLVTTGTPIALLIENVDQRSKDYADIAGAYRPGHADFTYDIKY
CCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEEE
GIRDHRGGGRSSARETATRVAAGAIAAKVLPGVTVRGAVVRIGEIEIDRSRWDWNEVPNN
CCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEEEEECCCCCCCCCCCC
PFFCPDPKTVPLWEEYLDAVRKAGSSIGAVVELVAEGVPAGLGAPLYGKLDADLASALLG
CEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
INAAKGVEIGEGFNAAQLTGEENADEMRLGNEGRPQFLSNHAGGILGGIATGAPIVARFA
CCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCCHHHHCCCCCHHHHHHCCCHHHHHEE
LKPTSSILTPRQTVDRTGQETEIFTKGRHDPCVGIRAVPVGEAMMWCVLADHFLRHRGQV
CCCCHHHCCCHHHHHCCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCC
GESVAWPFKG
CCCCCCCCCC
>Mature Secondary Structure 
SFNTFGHLFRVTTFGESHGAAIGCVVDGCPPNLRFTLEDVQAALDRRRPGQSRFTTQRR
CCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHCCCCC
EPDQVKVLSGTLEHPEGGLVTTGTPIALLIENVDQRSKDYADIAGAYRPGHADFTYDIKY
CCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEEE
GIRDHRGGGRSSARETATRVAAGAIAAKVLPGVTVRGAVVRIGEIEIDRSRWDWNEVPNN
CCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEEEEECCCCCCCCCCCC
PFFCPDPKTVPLWEEYLDAVRKAGSSIGAVVELVAEGVPAGLGAPLYGKLDADLASALLG
CEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
INAAKGVEIGEGFNAAQLTGEENADEMRLGNEGRPQFLSNHAGGILGGIATGAPIVARFA
CCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCCHHHHCCCCCHHHHHHCCCHHHHHEE
LKPTSSILTPRQTVDRTGQETEIFTKGRHDPCVGIRAVPVGEAMMWCVLADHFLRHRGQV
CCCCHHHCCCHHHHHCCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCC
GESVAWPFKG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA