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The map label for this gene is 154248021

Identifier: 154248021

GI number: 154248021

Start: 4537081

End: 4538499

Strand: Reverse

Name: 154248021

Synonym: Xaut_4100

Alternate gene names: NA

Gene position: 4538499-4537081 (Counterclockwise)

Preceding gene: 154248022

Following gene: 154248020

Centisome position: 85.49

GC content: 70.47

Gene sequence:

>1419_bases
ATGGCCGAGCGCGTCGCCCTCGTCACCGGGTCGCTGGCCGAGCCGCGCATCCGCCGCATCGCGGAGGAGATCGCGGACGA
GGCGCTGGACCCGGTGGTGGTCAATGTGGGCGTGAAGGTCGCGGCGCTGATGACGGCGGAGATCGTGGAACGGCGCCTCA
AGCTGCCGGAGCGCATCGACCGCGTGCTCATGCCCGGCCGCTTCCGCGGCGATCTCGACCGCCTCGCCACCCGCTTCGGC
CTGCCGTTCGCGCGCGGGCCGGAGGAGGCCGCGGACATCCCGGCCTATTTCGGCAAGGGTCGCGGCGGCGCCGTGAACCT
CGACCGGCAGGACGTGCTGCTGTTCGCCGAGATCGTGGACGCCACCCGCCTCTCCATCGACGAGCTTCTCACCCGCGCCC
GCGTCCTGCGCGGCGAGGGCGCGGACGTGATCGACCTCGGCGCCCTGCCCGACAACCCCTTCCCCCACCTGGAAGACGCC
ATCGCCGCACTGAAGGCGGACGGCTTCAGGGTGAGCGTGGACAGCTTCGACCCGCAGGAACTGGCGCGCGGCACCCGCGC
CGGGGCCGATTATCTCCTCAGCCTCAACGAGCACACCCTCGTCATCGCCGAGGAAGGCCCGGCCGTTCCGGTGCTGGTGC
CGGCGCAGGCGGGGGATCTGGCCTCCCTCATCCGCGCGGTGGAATTGTGCGAGGCCAGGGGCCGGCCGTTTCTGGCCGAT
CCCATCCTCGATCCCATCCATCTGGGCTTCACCGCCTCGCTGCTGCGCTACGCCGAGCTGCGGCGGCTGAAGCCGGACAT
TCCCATCCTCATGGGCATCGGCAATGTCACCGAGCTGACCGATGCCGACACCACCGGCATGAACGCCCTGCTCATGGGCA
TCATCTCCGAATTGAGGCTGAACGCGGTGCTGGCGGTGCAGGTGAGCCCCCATTGCCGCACCGCCATCCGCGAGTTCGAC
CGGGCGCGGCGGGAATTCTTCGCCGCGCGGGAGGCGGGCGCCCTGCCCCAGGGCTTCGGCGGCGGCCTGATGGCCCTGCG
TGACCGTCGCCCCTTCACCACCACGCCCGAGGAGGTGGACCGCCTCGCCGGCACGGTGGCCGACCGCAACTTCCGCATCG
AGGTGACGGACAGGGGCATCCACGCCTACAACCGCGACGGCCACCATGTGGCGCGCGACCCGTTCGACCTGTTCCCCCAC
CTCAAGGTGGAGGACGACGGCGCCCACGCCTTCTATCTCGGCGTGGAAACGGCGCGGGCGGAGATCGCCCTGAAGCTGGG
CAAGCGCTACACCCAGGACGAGCCGCTGAAATGGGGCGTGGTCGGCGAGACCTCGGCCAGCGCCGAGGACGCCCACCGGT
TGACTTTCAAGGAAGCGGGCTCGACCCTTTCCGCAAAGAAGAAGGGCGACGCCACGTGA

Upstream 100 bases:

>100_bases
GAGGCGACCACTGTGGCCGAGACCCTGGACGAGCTGCGCGACGCCATCGCCCGCCGCCGGGCGGAACTCGCCGCGCTCTT
CCCCGCGCCGGCGGCCTGAG

Downstream 100 bases:

>100_bases
TCCGGGAGACCATCGTCACCACCCAATCGACCGCGGGCGAGCCCCATGTGGCGCCCATGGGCGCGACCCTCGTGGAGGGC
GGCTACCTGCTCCAGCCGTT

Product: dihydropteroate synthase DHPS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MAERVALVTGSLAEPRIRRIAEEIADEALDPVVVNVGVKVAALMTAEIVERRLKLPERIDRVLMPGRFRGDLDRLATRFG
LPFARGPEEAADIPAYFGKGRGGAVNLDRQDVLLFAEIVDATRLSIDELLTRARVLRGEGADVIDLGALPDNPFPHLEDA
IAALKADGFRVSVDSFDPQELARGTRAGADYLLSLNEHTLVIAEEGPAVPVLVPAQAGDLASLIRAVELCEARGRPFLAD
PILDPIHLGFTASLLRYAELRRLKPDIPILMGIGNVTELTDADTTGMNALLMGIISELRLNAVLAVQVSPHCRTAIREFD
RARREFFAAREAGALPQGFGGGLMALRDRRPFTTTPEEVDRLAGTVADRNFRIEVTDRGIHAYNRDGHHVARDPFDLFPH
LKVEDDGAHAFYLGVETARAEIALKLGKRYTQDEPLKWGVVGETSASAEDAHRLTFKEAGSTLSAKKKGDAT

Sequences:

>Translated_472_residues
MAERVALVTGSLAEPRIRRIAEEIADEALDPVVVNVGVKVAALMTAEIVERRLKLPERIDRVLMPGRFRGDLDRLATRFG
LPFARGPEEAADIPAYFGKGRGGAVNLDRQDVLLFAEIVDATRLSIDELLTRARVLRGEGADVIDLGALPDNPFPHLEDA
IAALKADGFRVSVDSFDPQELARGTRAGADYLLSLNEHTLVIAEEGPAVPVLVPAQAGDLASLIRAVELCEARGRPFLAD
PILDPIHLGFTASLLRYAELRRLKPDIPILMGIGNVTELTDADTTGMNALLMGIISELRLNAVLAVQVSPHCRTAIREFD
RARREFFAAREAGALPQGFGGGLMALRDRRPFTTTPEEVDRLAGTVADRNFRIEVTDRGIHAYNRDGHHVARDPFDLFPH
LKVEDDGAHAFYLGVETARAEIALKLGKRYTQDEPLKWGVVGETSASAEDAHRLTFKEAGSTLSAKKKGDAT
>Mature_471_residues
AERVALVTGSLAEPRIRRIAEEIADEALDPVVVNVGVKVAALMTAEIVERRLKLPERIDRVLMPGRFRGDLDRLATRFGL
PFARGPEEAADIPAYFGKGRGGAVNLDRQDVLLFAEIVDATRLSIDELLTRARVLRGEGADVIDLGALPDNPFPHLEDAI
AALKADGFRVSVDSFDPQELARGTRAGADYLLSLNEHTLVIAEEGPAVPVLVPAQAGDLASLIRAVELCEARGRPFLADP
ILDPIHLGFTASLLRYAELRRLKPDIPILMGIGNVTELTDADTTGMNALLMGIISELRLNAVLAVQVSPHCRTAIREFDR
ARREFFAAREAGALPQGFGGGLMALRDRRPFTTTPEEVDRLAGTVADRNFRIEVTDRGIHAYNRDGHHVARDPFDLFPHL
KVEDDGAHAFYLGVETARAEIALKLGKRYTQDEPLKWGVVGETSASAEDAHRLTFKEAGSTLSAKKKGDAT

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: NA

Molecular weight: Translated: 51429; Mature: 51298

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERVALVTGSLAEPRIRRIAEEIADEALDPVVVNVGVKVAALMTAEIVERRLKLPERID
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCHHHHH
RVLMPGRFRGDLDRLATRFGLPFARGPEEAADIPAYFGKGRGGAVNLDRQDVLLFAEIVD
HHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCHHHCCCCCCEECCCHHHHHHHHHHHH
ATRLSIDELLTRARVLRGEGADVIDLGALPDNPFPHLEDAIAALKADGFRVSVDSFDPQE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHH
LARGTRAGADYLLSLNEHTLVIAEEGPAVPVLVPAQAGDLASLIRAVELCEARGRPFLAD
HHHHHCCCCCEEEECCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCC
PILDPIHLGFTASLLRYAELRRLKPDIPILMGIGNVTELTDADTTGMNALLMGIISELRL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHC
NAVLAVQVSPHCRTAIREFDRARREFFAAREAGALPQGFGGGLMALRDRRPFTTTPEEVD
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHH
RLAGTVADRNFRIEVTDRGIHAYNRDGHHVARDPFDLFPHLKVEDDGAHAFYLGVETARA
HHHHHHCCCCEEEEEEECCCEEECCCCCCCCCCCHHHCCCCEEECCCCEEEEEEEHHHHH
EIALKLGKRYTQDEPLKWGVVGETSASAEDAHRLTFKEAGSTLSAKKKGDAT
HHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AERVALVTGSLAEPRIRRIAEEIADEALDPVVVNVGVKVAALMTAEIVERRLKLPERID
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCHHHHH
RVLMPGRFRGDLDRLATRFGLPFARGPEEAADIPAYFGKGRGGAVNLDRQDVLLFAEIVD
HHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCHHHCCCCCCEECCCHHHHHHHHHHHH
ATRLSIDELLTRARVLRGEGADVIDLGALPDNPFPHLEDAIAALKADGFRVSVDSFDPQE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHH
LARGTRAGADYLLSLNEHTLVIAEEGPAVPVLVPAQAGDLASLIRAVELCEARGRPFLAD
HHHHHCCCCCEEEECCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCC
PILDPIHLGFTASLLRYAELRRLKPDIPILMGIGNVTELTDADTTGMNALLMGIISELRL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHC
NAVLAVQVSPHCRTAIREFDRARREFFAAREAGALPQGFGGGLMALRDRRPFTTTPEEVD
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHH
RLAGTVADRNFRIEVTDRGIHAYNRDGHHVARDPFDLFPHLKVEDDGAHAFYLGVETARA
HHHHHHCCCCEEEEEEECCCEEECCCCCCCCCCCHHHCCCCEEECCCCEEEEEEEHHHHH
EIALKLGKRYTQDEPLKWGVVGETSASAEDAHRLTFKEAGSTLSAKKKGDAT
HHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]