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The map label for this gene is kstR2 [H]

Identifier: 154247994

GI number: 154247994

Start: 4506874

End: 4507545

Strand: Reverse

Name: kstR2 [H]

Synonym: Xaut_4073

Alternate gene names: 154247994

Gene position: 4507545-4506874 (Counterclockwise)

Preceding gene: 154247995

Following gene: 154247993

Centisome position: 84.9

GC content: 69.94

Gene sequence:

>672_bases
ATGGCGCCTCCGAAACCCACCGCCGCCGCGATGGCGGATCCCTCACCCTGGCGCTCCCCCGCCCAGCGCGGGCGCGACCG
GGCGCTGAAGCGCGAGGCAGTGCTGAAGGCGGCGGCGCGGCTGTTCAACGAGAAGGGCTTTCACGCCACCTCGCTGGATG
ACGTGGCGCGGCAGCTGAACGTCACCAAGCCGACGCTCTATCATTACTTCCGCAGCAAGGACGACGTGCTGTTCGAATGC
TGCCGCATGGGGCTGGAGATGATCGAGGCGGCGGCGGCAACCGTGCCGGGCTCCCAGGCCAGCGGCCTCGAACGGCTGCG
CGCGCTGATGGAGCAGTATGCCGAGGCCATGACCATGGACTTCGGCATGAGCATCAGCCGCACCCCGGACACCGCCCTGT
CGCCCGAGAACCGCGCTGAGCTGCGGCGCCTGAAAGCGCAGATCGACCGGGCCCTGCGCGGCGTGATCCAGAGCGGCATC
GAGGACGGCTCCATCGCCCCCTGTGATGTGCGCACCGCCGCCTTCGCCATCGCCGGCGCGCTGAACGCCATCGCCCATTG
GTACAAGCCCGACGGCCCCCTCGCGCCGGCCGAGATCGCCCGGCAGACCGCCGATTTTCTCATCCAGGGCCTTGCGCCCC
GCACCTCAGAACGACGCCAGCCCAAGCGCTGA

Upstream 100 bases:

>100_bases
GCATTCCCTTGACCGTAAAGTTACTCATGAGTAACTTTACGTCCCACAGGTCGGACGGCTTCCCGCGAAGTCGCCTTCCC
CCTCCCGGCCGGACCTTGCG

Downstream 100 bases:

>100_bases
GCCTCGCCCCCAACGGAGGACACCCCATGGCCCTGCCCGCCGCGTTCCGCGATCTTGCCATCCCGGCCATCGCCTCGCCC
ATGTTCCTCGCCTCCGGCCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MAPPKPTAAAMADPSPWRSPAQRGRDRALKREAVLKAAARLFNEKGFHATSLDDVARQLNVTKPTLYHYFRSKDDVLFEC
CRMGLEMIEAAAATVPGSQASGLERLRALMEQYAEAMTMDFGMSISRTPDTALSPENRAELRRLKAQIDRALRGVIQSGI
EDGSIAPCDVRTAAFAIAGALNAIAHWYKPDGPLAPAEIARQTADFLIQGLAPRTSERRQPKR

Sequences:

>Translated_223_residues
MAPPKPTAAAMADPSPWRSPAQRGRDRALKREAVLKAAARLFNEKGFHATSLDDVARQLNVTKPTLYHYFRSKDDVLFEC
CRMGLEMIEAAAATVPGSQASGLERLRALMEQYAEAMTMDFGMSISRTPDTALSPENRAELRRLKAQIDRALRGVIQSGI
EDGSIAPCDVRTAAFAIAGALNAIAHWYKPDGPLAPAEIARQTADFLIQGLAPRTSERRQPKR
>Mature_222_residues
APPKPTAAAMADPSPWRSPAQRGRDRALKREAVLKAAARLFNEKGFHATSLDDVARQLNVTKPTLYHYFRSKDDVLFECC
RMGLEMIEAAAATVPGSQASGLERLRALMEQYAEAMTMDFGMSISRTPDTALSPENRAELRRLKAQIDRALRGVIQSGIE
DGSIAPCDVRTAAFAIAGALNAIAHWYKPDGPLAPAEIARQTADFLIQGLAPRTSERRQPKR

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24446; Mature: 24315

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPKPTAAAMADPSPWRSPAQRGRDRALKREAVLKAAARLFNEKGFHATSLDDVARQLN
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
VTKPTLYHYFRSKDDVLFECCRMGLEMIEAAAATVPGSQASGLERLRALMEQYAEAMTMD
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
FGMSISRTPDTALSPENRAELRRLKAQIDRALRGVIQSGIEDGSIAPCDVRTAAFAIAGA
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LNAIAHWYKPDGPLAPAEIARQTADFLIQGLAPRTSERRQPKR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
APPKPTAAAMADPSPWRSPAQRGRDRALKREAVLKAAARLFNEKGFHATSLDDVARQLN
CCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
VTKPTLYHYFRSKDDVLFECCRMGLEMIEAAAATVPGSQASGLERLRALMEQYAEAMTMD
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
FGMSISRTPDTALSPENRAELRRLKAQIDRALRGVIQSGIEDGSIAPCDVRTAAFAIAGA
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LNAIAHWYKPDGPLAPAEIARQTADFLIQGLAPRTSERRQPKR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA