BacMap

Definition	Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession	NC_009720
Length	5,308,934

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The map label for this gene is fabG [H]

Identifier: 154247989

GI number: 154247989

Start: 4502559

End: 4503383

Strand: Reverse

Name: fabG [H]

Synonym: Xaut_4068

Alternate gene names: 154247989

Gene position: 4503383-4502559 (Counterclockwise)

Preceding gene: 154247990

Following gene: 154247988

Centisome position: 84.83

GC content: 67.15

Gene sequence:

>825_bases
ATGACGAAGCTTACGGGCAAGGTCGCCTATGTGACCGGGGCCGGCCGCGGCATCGGCCGGGCCATCGCCCTGAAACTGGC
GGGCGAAGGCGCGCGCCTCGTCCTCAACGATCTGGACGCCGAGCCGGTGGAGGCCGTCCGCGCCGAGATCCTGGCGCTGG
GCGGCGAGGCCATCGCCGTTCCCGGATCGGTGACGGCAGAGGGCTTCGCCCAGAGCTTCATCGATCACGGCATCGCCGCG
TTCGATGGCATCGACATCATCGTCAACAATGCCGGCTACACCTGGGACAGCCTGATCGGCAAGATGAGCGACGCGCAGTT
CGACGCCATCCTCGACGTGCATCTGAAGGCGCCGTTCCAGATCCTGCGCGCCGCCGCCGAGCCGATCCGCATCCGCGCGG
CGCAGGAGGCCGCCGAAGGCCGCGAGGTGTTCCGCAAGGTGGTGAACATCTCCTCCATCGCCGGCACCGGCGGCAACATG
GGCCAGGCCAACTACGCCTCCGCCAAGGCCGGAATCATCGGCCTCACCAAGACGCTGTCGAAGGAATGGGGGCGCTTCAA
GGTGAACGTGAACTGCGTCGCCTTCGGTCTCATCGAGACCCGCATGACGGCGGCCTCCGAGACCAAGGCCTCCATCACCG
TGGAGGGCAACCAGGTGGCCATCGGCCTGCCGCCCAAGGTGCTGGACGGCTTCCGAAGCCTCATCCCGCTGGGTCGCGCC
GGCACGCCACAGGAAGCCGCCGACGGCGTCTATCTCTTCTGCGCGCCGGAATCCAACTATGTGAGCGGACAGGTGCTGGT
GGTCGGCGGCGGTATTTCTTTCTGA

Upstream 100 bases:

>100_bases
CGCGCCTCGACCTTGCCGTCCGCGACCAGAACGGCGAACAGAAACTGTCCGGCGCGGCGATCCTCGCGCTCACCTCCCAG
AATTGCTGAAAGGCGCAGTC

Downstream 100 bases:

>100_bases
ACGCCTGTTTGGAAATTCGCTGGGATGGGCGCTCGTAGCCGTCGCAGCCGCCTTTCCGTCGTCATGGCCGGGCCTGACCC
GGCCATCCACGTGGCCGGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTKLTGKVAYVTGAGRGIGRAIALKLAGEGARLVLNDLDAEPVEAVRAEILALGGEAIAVPGSVTAEGFAQSFIDHGIAA
FDGIDIIVNNAGYTWDSLIGKMSDAQFDAILDVHLKAPFQILRAAAEPIRIRAAQEAAEGREVFRKVVNISSIAGTGGNM
GQANYASAKAGIIGLTKTLSKEWGRFKVNVNCVAFGLIETRMTAASETKASITVEGNQVAIGLPPKVLDGFRSLIPLGRA
GTPQEAADGVYLFCAPESNYVSGQVLVVGGGISF

Sequences:

>Translated_274_residues
MTKLTGKVAYVTGAGRGIGRAIALKLAGEGARLVLNDLDAEPVEAVRAEILALGGEAIAVPGSVTAEGFAQSFIDHGIAA
FDGIDIIVNNAGYTWDSLIGKMSDAQFDAILDVHLKAPFQILRAAAEPIRIRAAQEAAEGREVFRKVVNISSIAGTGGNM
GQANYASAKAGIIGLTKTLSKEWGRFKVNVNCVAFGLIETRMTAASETKASITVEGNQVAIGLPPKVLDGFRSLIPLGRA
GTPQEAADGVYLFCAPESNYVSGQVLVVGGGISF
>Mature_273_residues
TKLTGKVAYVTGAGRGIGRAIALKLAGEGARLVLNDLDAEPVEAVRAEILALGGEAIAVPGSVTAEGFAQSFIDHGIAAF
DGIDIIVNNAGYTWDSLIGKMSDAQFDAILDVHLKAPFQILRAAAEPIRIRAAQEAAEGREVFRKVVNISSIAGTGGNMG
QANYASAKAGIIGLTKTLSKEWGRFKVNVNCVAFGLIETRMTAASETKASITVEGNQVAIGLPPKVLDGFRSLIPLGRAG
TPQEAADGVYLFCAPESNYVSGQVLVVGGGISF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=282, Percent_Identity=34.3971631205674, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4504505, Length=199, Percent_Identity=38.1909547738693, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI32483357, Length=277, Percent_Identity=29.9638989169675, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI40254992, Length=268, Percent_Identity=30.5970149253731, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=29.3040293040293, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4758504, Length=276, Percent_Identity=28.6231884057971, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI10190704, Length=273, Percent_Identity=28.9377289377289, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI83715985, Length=276, Percent_Identity=27.8985507246377, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI126723750, Length=279, Percent_Identity=25.8064516129032, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=26.3537906137184, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=31.5270935960591, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723191, Length=200, Percent_Identity=30.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI59889578, Length=246, Percent_Identity=27.2357723577236, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=277, Percent_Identity=24.5487364620939, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI7705925, Length=268, Percent_Identity=24.2537313432836, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=267, Percent_Identity=35.9550561797753, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789208, Length=268, Percent_Identity=28.7313432835821, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=268, Percent_Identity=31.7164179104478, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082100, Length=275, Percent_Identity=31.2727272727273, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787905, Length=273, Percent_Identity=30.4029304029304, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790717, Length=269, Percent_Identity=27.5092936802974, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789378, Length=273, Percent_Identity=29.6703296703297, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI2367175, Length=274, Percent_Identity=28.4671532846715, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=275, Percent_Identity=26.5454545454545, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788459, Length=269, Percent_Identity=27.5092936802974, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=273, Percent_Identity=35.5311355311355, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25147288, Length=274, Percent_Identity=34.3065693430657, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17568967, Length=215, Percent_Identity=35.3488372093023, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=283, Percent_Identity=30.3886925795053, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=287, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=287, Percent_Identity=28.2229965156794, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=291, Percent_Identity=28.1786941580756, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=290, Percent_Identity=29.6551724137931, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=271, Percent_Identity=28.7822878228782, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=280, Percent_Identity=28.2142857142857, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=283, Percent_Identity=29.6819787985866, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=273, Percent_Identity=28.2051282051282, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=286, Percent_Identity=27.972027972028, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=292, Percent_Identity=28.0821917808219, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=294, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=284, Percent_Identity=29.9295774647887, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=285, Percent_Identity=29.4736842105263, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=284, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=298, Percent_Identity=27.5167785234899, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=283, Percent_Identity=27.5618374558304, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=270, Percent_Identity=25.9259259259259, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=268, Percent_Identity=25.7462686567164, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=289, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=278, Percent_Identity=26.978417266187, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=274, Percent_Identity=27.7372262773723, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=291, Percent_Identity=25.085910652921, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=185, Percent_Identity=31.3513513513514, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=26.3345195729537, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=278, Percent_Identity=25.5395683453237, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=213, Percent_Identity=27.6995305164319, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=270, Percent_Identity=25.1851851851852, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=277, Percent_Identity=31.7689530685921, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324126, Length=274, Percent_Identity=27.7372262773723, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639444, Length=271, Percent_Identity=34.6863468634686, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=36, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=276, Percent_Identity=28.6231884057971, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644339, Length=268, Percent_Identity=27.9850746268657, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24643142, Length=272, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI23397609, Length=269, Percent_Identity=28.6245353159851, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737361, Length=280, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=277, Percent_Identity=27.0758122743682, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=273, Percent_Identity=26.007326007326, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28418; Mature: 28287

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTGKVAYVTGAGRGIGRAIALKLAGEGARLVLNDLDAEPVEAVRAEILALGGEAIAV
CCCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEC
PGSVTAEGFAQSFIDHGIAAFDGIDIIVNNAGYTWDSLIGKMSDAQFDAILDVHLKAPFQ
CCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEEEEECCHHH
ILRAAAEPIRIRAAQEAAEGREVFRKVVNISSIAGTGGNMGQANYASAKAGIIGLTKTLS
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHH
KEWGRFKVNVNCVAFGLIETRMTAASETKASITVEGNQVAIGLPPKVLDGFRSLIPLGRA
HCCCEEEEEEEEEEEEEHHHHHHHCCCCCEEEEEECCEEEEECCHHHHHHHHHHCCCCCC
GTPQEAADGVYLFCAPESNYVSGQVLVVGGGISF
CCCCHHCCCEEEEECCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TKLTGKVAYVTGAGRGIGRAIALKLAGEGARLVLNDLDAEPVEAVRAEILALGGEAIAV
CCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEC
PGSVTAEGFAQSFIDHGIAAFDGIDIIVNNAGYTWDSLIGKMSDAQFDAILDVHLKAPFQ
CCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCCCHHHHHHCCCCCCEEEEEEEEECCHHH
ILRAAAEPIRIRAAQEAAEGREVFRKVVNISSIAGTGGNMGQANYASAKAGIIGLTKTLS
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHH
KEWGRFKVNVNCVAFGLIETRMTAASETKASITVEGNQVAIGLPPKVLDGFRSLIPLGRA
HCCCEEEEEEEEEEEEEHHHHHHHCCCCCEEEEEECCEEEEECCHHHHHHHHHHCCCCCC
GTPQEAADGVYLFCAPESNYVSGQVLVVGGGISF
CCCCHHCCCEEEEECCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]