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The map label for this gene is dinB1 [H]

Identifier: 154247780

GI number: 154247780

Start: 4274261

End: 4275559

Strand: Reverse

Name: dinB1 [H]

Synonym: Xaut_3857

Alternate gene names: 154247780

Gene position: 4275559-4274261 (Counterclockwise)

Preceding gene: 154247781

Following gene: 154247779

Centisome position: 80.54

GC content: 71.29

Gene sequence:

>1299_bases
ATGACCGCCCCCGGCTTTTGCCGCGATTGCCTGTGCGATGCGCCCCAGACAGGTGGCCTTGCCGGCGACCGCTGCCCGGC
CTGCGGCAGCCCTCGCCTGCTGCGGCATCGGGAGCTGGACACCCTCAGCGTCGCTCATGTGGATTGCGACGCCTTCTTCG
CCGCCGTGGAAAAGCGCGACGACCCGAGCCTTGCCGACGTGCCACTCATCATCGGCGGCGGCAAGCGCGGGGTGGTCTCC
ACCGCCTGCTACATCGCGCGCATCAAGGGCGTGCGCTCGGCCATGCCCATGTTCAAGGCGCTGGCGCTCTGCCCCGAGGC
GGTGGTGCTGAAGCCGAACATGGAGAAATACCGCACGGTGGGACGGCAGGTGCGGGCCATGATGCAGCAGCTCACCCCGC
TGGTGGAGCCGCTCTCCATCGACGAGGCCTTCCTCGACCTTTCGGGCACGCAGGCGCTGCATGGCGCCAGCCCCGCCCGC
ACGCTGGCGCGATTCGCGCAGGCGGTGGAGCGGGAGGTGGGCATCACCGTCTCGGTGGGGCTCGCGGCCAACAAGTTCCT
CGCCAAGATCGCCTCCGACCTCGACAAGCCGCGCGGCTTCTCGGTGCTGGGGCAGACGGAGGCGGCGGGCTTCCTCGCGC
CGCGCCCCGCCACCTTCATCTGGGGCGTGGGGGCGGCGTTCGGCGGCAAGCTGGCGAAGGACGGCTTCCACACCATCGCC
GACCTCCAGCGCGCCGCCCCCGCCGACCTTGCCCGGCGCTATGGCGCGGAAGGGCTGCGCCTGTCGCGCCTCGCCTTCGG
CGTCGATACCCGCGCGGTGGAGCCGGAGCGGGAGGCCAAAAGCGTTTCGGCGGAAACCACCTTCGAGCGCGACATGGGCG
CCCTGCGCCCGCTGGAGCAGACCCTCTACGCCCTCTCCGAAGAGGTCAGCGACCGCCTCAAGCATGCCGGCATCGCCGGC
CGCGCGGTCACCTTGAAGCTGAAGAGTGCCGACTTCCGCTTGCGCACCCGCTCGCGCACCCTGGAGGCCCCCACCTGCCT
TGCCGCCCGCATCAACAACGCGGCGCGGGAGCTGCTGGCGAAGGAGGTGGACGGCACGCTGTTCCGCCTCATCGGCGTGG
GGGTCTCGGACCTCTGCCCCATCGCCGACGCCGACCCGGCGGATCTCGTGGACACCTCCACCGAGCGCCTGAAGGCGGCG
GAAAACGCCATGGACGAGCTGCGCGCCCGATTCGGCCGCGGCGCCCTCACCCGCGGCATCCTGCTGGACGCCACCACGGA
CCGGCGCAGACGGAAATAG

Upstream 100 bases:

>100_bases
GCGGTCGCTCTACATCAGCAAGGGCCGGAGCGACCGCAGGTCGCCCTCCGTCAGCAAGGACGAGGATGACCACGCGACTC
TCCCGCCTGGGACAGTCGTC

Downstream 100 bases:

>100_bases
AGTGGCGCCATACTGCGCCGCAGCGAGTTCCGCTTGACTTACGCTATATCTAAATGAATATAGCTTCCACGCAGATGCCA
CCACGGGAGGCCCCTTCATG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTAPGFCRDCLCDAPQTGGLAGDRCPACGSPRLLRHRELDTLSVAHVDCDAFFAAVEKRDDPSLADVPLIIGGGKRGVVS
TACYIARIKGVRSAMPMFKALALCPEAVVLKPNMEKYRTVGRQVRAMMQQLTPLVEPLSIDEAFLDLSGTQALHGASPAR
TLARFAQAVEREVGITVSVGLAANKFLAKIASDLDKPRGFSVLGQTEAAGFLAPRPATFIWGVGAAFGGKLAKDGFHTIA
DLQRAAPADLARRYGAEGLRLSRLAFGVDTRAVEPEREAKSVSAETTFERDMGALRPLEQTLYALSEEVSDRLKHAGIAG
RAVTLKLKSADFRLRTRSRTLEAPTCLAARINNAARELLAKEVDGTLFRLIGVGVSDLCPIADADPADLVDTSTERLKAA
ENAMDELRARFGRGALTRGILLDATTDRRRRK

Sequences:

>Translated_432_residues
MTAPGFCRDCLCDAPQTGGLAGDRCPACGSPRLLRHRELDTLSVAHVDCDAFFAAVEKRDDPSLADVPLIIGGGKRGVVS
TACYIARIKGVRSAMPMFKALALCPEAVVLKPNMEKYRTVGRQVRAMMQQLTPLVEPLSIDEAFLDLSGTQALHGASPAR
TLARFAQAVEREVGITVSVGLAANKFLAKIASDLDKPRGFSVLGQTEAAGFLAPRPATFIWGVGAAFGGKLAKDGFHTIA
DLQRAAPADLARRYGAEGLRLSRLAFGVDTRAVEPEREAKSVSAETTFERDMGALRPLEQTLYALSEEVSDRLKHAGIAG
RAVTLKLKSADFRLRTRSRTLEAPTCLAARINNAARELLAKEVDGTLFRLIGVGVSDLCPIADADPADLVDTSTERLKAA
ENAMDELRARFGRGALTRGILLDATTDRRRRK
>Mature_431_residues
TAPGFCRDCLCDAPQTGGLAGDRCPACGSPRLLRHRELDTLSVAHVDCDAFFAAVEKRDDPSLADVPLIIGGGKRGVVST
ACYIARIKGVRSAMPMFKALALCPEAVVLKPNMEKYRTVGRQVRAMMQQLTPLVEPLSIDEAFLDLSGTQALHGASPART
LARFAQAVEREVGITVSVGLAANKFLAKIASDLDKPRGFSVLGQTEAAGFLAPRPATFIWGVGAAFGGKLAKDGFHTIAD
LQRAAPADLARRYGAEGLRLSRLAFGVDTRAVEPEREAKSVSAETTFERDMGALRPLEQTLYALSEEVSDRLKHAGIAGR
AVTLKLKSADFRLRTRSRTLEAPTCLAARINNAARELLAKEVDGTLFRLIGVGVSDLCPIADADPADLVDTSTERLKAAE
NAMDELRARFGRGALTRGILLDATTDRRRRK

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=257, Percent_Identity=31.9066147859922, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI84043967, Length=257, Percent_Identity=31.9066147859922, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI7705344, Length=422, Percent_Identity=24.6445497630332, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI154350220, Length=369, Percent_Identity=25.2032520325203, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1786425, Length=344, Percent_Identity=38.0813953488372, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787432, Length=394, Percent_Identity=25.6345177664975, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=413, Percent_Identity=30.2663438256659, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=361, Percent_Identity=28.808864265928, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=362, Percent_Identity=24.585635359116, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19923006, Length=437, Percent_Identity=25.4004576659039, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355641, Length=280, Percent_Identity=28.9285714285714, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644984, Length=280, Percent_Identity=28.9285714285714, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24668444, Length=359, Percent_Identity=26.7409470752089, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46411; Mature: 46280

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPGFCRDCLCDAPQTGGLAGDRCPACGSPRLLRHRELDTLSVAHVDCDAFFAAVEKRD
CCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECHHHHHHHHHCCC
DPSLADVPLIIGGGKRGVVSTACYIARIKGVRSAMPMFKALALCPEAVVLKPNMEKYRTV
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHH
GRQVRAMMQQLTPLVEPLSIDEAFLDLSGTQALHGASPARTLARFAQAVEREVGITVSVG
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEC
LAANKFLAKIASDLDKPRGFSVLGQTEAAGFLAPRPATFIWGVGAAFGGKLAKDGFHTIA
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHEEECHHHHCCHHHHHHHHHHH
DLQRAAPADLARRYGAEGLRLSRLAFGVDTRAVEPEREAKSVSAETTFERDMGALRPLEQ
HHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
TLYALSEEVSDRLKHAGIAGRAVTLKLKSADFRLRTRSRTLEAPTCLAARINNAARELLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KEVDGTLFRLIGVGVSDLCPIADADPADLVDTSTERLKAAENAMDELRARFGRGALTRGI
HHHCHHHHHHHHCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCE
LLDATTDRRRRK
EEECCCHHHHCC
>Mature Secondary Structure 
TAPGFCRDCLCDAPQTGGLAGDRCPACGSPRLLRHRELDTLSVAHVDCDAFFAAVEKRD
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECHHHHHHHHHCCC
DPSLADVPLIIGGGKRGVVSTACYIARIKGVRSAMPMFKALALCPEAVVLKPNMEKYRTV
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHH
GRQVRAMMQQLTPLVEPLSIDEAFLDLSGTQALHGASPARTLARFAQAVEREVGITVSVG
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEC
LAANKFLAKIASDLDKPRGFSVLGQTEAAGFLAPRPATFIWGVGAAFGGKLAKDGFHTIA
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHEEECHHHHCCHHHHHHHHHHH
DLQRAAPADLARRYGAEGLRLSRLAFGVDTRAVEPEREAKSVSAETTFERDMGALRPLEQ
HHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
TLYALSEEVSDRLKHAGIAGRAVTLKLKSADFRLRTRSRTLEAPTCLAARINNAARELLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KEVDGTLFRLIGVGVSDLCPIADADPADLVDTSTERLKAAENAMDELRARFGRGALTRGI
HHHCHHHHHHHHCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHCCE
LLDATTDRRRRK
EEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]