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The map label for this gene is gltX [H]

Identifier: 154247763

GI number: 154247763

Start: 4257359

End: 4258306

Strand: Reverse

Name: gltX [H]

Synonym: Xaut_3840

Alternate gene names: 154247763

Gene position: 4258306-4257359 (Counterclockwise)

Preceding gene: 154247767

Following gene: 154247759

Centisome position: 80.21

GC content: 70.99

Gene sequence:

>948_bases
ATGCCTTCCAGCGCCATGTCATCCACGGCCATGTCCCATCCCGCGCGCTTCACCTGCCGCTTCGCGCCCAGCCCCAACGG
CCGGCTGCATCTGGGCCACGCCTTCTCGGCGCTGGTGAATGTGGAGGCGGCGCGGCGCATGGGCGGTACCTTCCTGTTAC
GCCTGGAGGACATCGACACCACCCGATGTCGCCCGGAATATGCGCGCGGCATCCTCGACGACCTCTCCTGGCTGGGCGTC
GTCCCCGACGGCCCGGTGCGCCGGCAATCGGACCATTTCGCCGATTATGCCGCTGCCATCGCCCGGCTCGAAGCCCTGGG
GCTGGTCTATCCGGCGTTCGAGAGCCGGTCCGAGATCGCCGGCGCGGTGATCGGGCAGGAAAGCGCCACCGGCCGTCCTG
CCCCGCGCGATCCGGACGGGGCGCCGCTCAACCCCTTCCCCCGCGCCGCCATGAGCGATGCGGCGCGGGCTGCGCTGCGC
GACCAGGGCGCGCCGTTCGTGGTGCGGCTGGACATGGCAGCCTCCATCGCGGCGGTGAGCGACATGGGCGGTGGCCCGCT
CACGTGGGAGGAGGCGCAGGGCGTGCCCGAGGGCCCGCGCAAGACGGTGGAGGCCGATGCCGCCCGCTGGGGCGACGTGG
TGCTGGCCCGCAAGGACGTGCCCACCTCCTACCACCTCTCGGTGGTGGTGGACGATGCCGCGCAGGGCATCACCCACGTC
ATCCGCGGCATGGACCTTTATCACGCCACCTCGGTGCATGTGCTGCTGCAACGCCTGCTGGGCCTGCCGACGCCGATCTA
TCACCACCACCGGCTGATTCTGGACGACAGCGGCTACAAGCTCTCCAAGAGCAATTCCGCCACCAGCCTTGCCGCCCTGC
GCGCCGCCGGCGCCACCCCGCAGGATGTGCTGCGGCGGCTGTCGCTTCAGCCGACCCCGAGCACGTAG

Upstream 100 bases:

>100_bases
CAAGCGCATCAGCCCACTGCGCGCGAAAATCCTGTGTCCACGCATCTCGTTCACGCGAACCGGGATCCCCTTCGCGCGAA
AACGCTCTAATCCTAGCGCC

Downstream 100 bases:

>100_bases
AGCCAGAGCGCCACCGTGAACACCGCAAGCCCGGTGGACATGGACACGGCACTGGTGGAGGCCCCCACCCCGATGCCGTA
GCGCTGGGCCAGAAGATAGC

Product: glutamyl-tRNA synthetase class Ic

Products: NA

Alternate protein names: Glutamate--tRNA ligase; GluRS [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPSSAMSSTAMSHPARFTCRFAPSPNGRLHLGHAFSALVNVEAARRMGGTFLLRLEDIDTTRCRPEYARGILDDLSWLGV
VPDGPVRRQSDHFADYAAAIARLEALGLVYPAFESRSEIAGAVIGQESATGRPAPRDPDGAPLNPFPRAAMSDAARAALR
DQGAPFVVRLDMAASIAAVSDMGGGPLTWEEAQGVPEGPRKTVEADAARWGDVVLARKDVPTSYHLSVVVDDAAQGITHV
IRGMDLYHATSVHVLLQRLLGLPTPIYHHHRLILDDSGYKLSKSNSATSLAALRAAGATPQDVLRRLSLQPTPST

Sequences:

>Translated_315_residues
MPSSAMSSTAMSHPARFTCRFAPSPNGRLHLGHAFSALVNVEAARRMGGTFLLRLEDIDTTRCRPEYARGILDDLSWLGV
VPDGPVRRQSDHFADYAAAIARLEALGLVYPAFESRSEIAGAVIGQESATGRPAPRDPDGAPLNPFPRAAMSDAARAALR
DQGAPFVVRLDMAASIAAVSDMGGGPLTWEEAQGVPEGPRKTVEADAARWGDVVLARKDVPTSYHLSVVVDDAAQGITHV
IRGMDLYHATSVHVLLQRLLGLPTPIYHHHRLILDDSGYKLSKSNSATSLAALRAAGATPQDVLRRLSLQPTPST
>Mature_314_residues
PSSAMSSTAMSHPARFTCRFAPSPNGRLHLGHAFSALVNVEAARRMGGTFLLRLEDIDTTRCRPEYARGILDDLSWLGVV
PDGPVRRQSDHFADYAAAIARLEALGLVYPAFESRSEIAGAVIGQESATGRPAPRDPDGAPLNPFPRAAMSDAARAALRD
QGAPFVVRLDMAASIAAVSDMGGGPLTWEEAQGVPEGPRKTVEADAARWGDVVLARKDVPTSYHLSVVVDDAAQGITHVI
RGMDLYHATSVHVLLQRLLGLPTPIYHHHRLILDDSGYKLSKSNSATSLAALRAAGATPQDVLRRLSLQPTPST

Specific function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction:glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) [H]

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=293, Percent_Identity=33.7883959044369, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1788743, Length=292, Percent_Identity=31.5068493150685, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI226510925, Length=275, Percent_Identity=31.2727272727273, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786895, Length=159, Percent_Identity=33.9622641509434, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71993394, Length=298, Percent_Identity=28.5234899328859, Blast_Score=101, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324540, Length=290, Percent_Identity=30, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24665321, Length=309, Percent_Identity=29.4498381877023, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR004527
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: =6.1.1.17 [H]

Molecular weight: Translated: 33679; Mature: 33547

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSAMSSTAMSHPARFTCRFAPSPNGRLHLGHAFSALVNVEAARRMGGTFLLRLEDIDT
CCCHHHHHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCC
TRCRPEYARGILDDLSWLGVVPDGPVRRQSDHFADYAAAIARLEALGLVYPAFESRSEIA
CCCCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GAVIGQESATGRPAPRDPDGAPLNPFPRAAMSDAARAALRDQGAPFVVRLDMAASIAAVS
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
DMGGGPLTWEEAQGVPEGPRKTVEADAARWGDVVLARKDVPTSYHLSVVVDDAAQGITHV
CCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCHHHHHHHH
IRGMDLYHATSVHVLLQRLLGLPTPIYHHHRLILDDSGYKLSKSNSATSLAALRAAGATP
HHCCHHHHHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCEEECCCCHHHHHHHHHCCCCH
QDVLRRLSLQPTPST
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
PSSAMSSTAMSHPARFTCRFAPSPNGRLHLGHAFSALVNVEAARRMGGTFLLRLEDIDT
CCHHHHHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCC
TRCRPEYARGILDDLSWLGVVPDGPVRRQSDHFADYAAAIARLEALGLVYPAFESRSEIA
CCCCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GAVIGQESATGRPAPRDPDGAPLNPFPRAAMSDAARAALRDQGAPFVVRLDMAASIAAVS
HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
DMGGGPLTWEEAQGVPEGPRKTVEADAARWGDVVLARKDVPTSYHLSVVVDDAAQGITHV
CCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCHHHHHHHH
IRGMDLYHATSVHVLLQRLLGLPTPIYHHHRLILDDSGYKLSKSNSATSLAALRAAGATP
HHCCHHHHHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCEEECCCCHHHHHHHHHCCCCH
QDVLRRLSLQPTPST
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA