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The map label for this gene is tig

Identifier: 154247517

GI number: 154247517

Start: 4013919

End: 4015277

Strand: Direct

Name: tig

Synonym: Xaut_3590

Alternate gene names: 154247517

Gene position: 4013919-4015277 (Clockwise)

Preceding gene: 154247516

Following gene: 154247518

Centisome position: 75.61

GC content: 66.23

Gene sequence:

>1359_bases
ATGCAGGTGACCGAGACCCAGGCCGATGGCCTCAAGCGCGCGTTCCGTGTGGTGGTGTCTGCCGCCGACCTCGGCGCCAA
GGCCGATGCCAAGCTGGCCGAACTCAAGGGCCAGGTGAAGCTGAACGGCTTCCGCCCCGGCAAGGTCCCCGTGGCGCACC
TCAAGCGCGTCTATGGCAAGTCCGTCATGTCCGAGGTGATCGAGCAGACGGTCAACGAGACCAACGGCAAGATCGTCGAG
GAGCACGGCTTCAAGCTGGCGCTCCAGCCCAAGGTCAAGCTGCCCGAGGAAGATCCCCAGGCCCAGGGCCTGCTGGAAGG
CGGCAAGGACCTCGCCTACGACCTCGAGATCGAGATCCTGCCCAAGATCGAGCTGGGCAACTTCAAGGACATCTCGGTGG
AGAAGCTGGTGGTCGAGGTGTCCGACGCGGAGGTCGACGAGACCATCCAGCGCATCGCCGACGCCAACCGCCCCTTCGTC
ACCCGTGAAGGCGGCTACGCCGAGAATGGCGACCGCGTCACCATCGACTTCACCGGCTATGTGGACGGCGAGAAGTTCCC
CGGCGGCGAGGGCCAGGACATCGACGTCCTGCTCGGTTCCAACGGCTTCATCCCCGGCTTCGAGGAGCAGCTGCTCGGCG
TCTATGCCGGCGACAACCGCACCCTCAACGTGACCTTCCCCGAGGCCTACGCCGCCAAGGAACTGGCCGGCAAGGCAGCG
ACCTTCGAAGTGACTGTGAAGTCGGTGGCCGCCCCCGGCCCGCTCACCCTGGACGACGAGTTCGCCAAGACCCTCGGCCA
GGAAAGCCTGGAGAAGCTCAAGGAGATGGTGCGCGCGCGCATCGCCAGCGAGCACGCCGGCGCCGCCCGCCAGAAGGTGA
AGCGCGCGCTGCTCGACGCCCTCGACACCACCCACCAGTTCGCGGTGCCGGAAGGCCTCGTGGAGCAGGAATTCTTCGGC
GTGTGGAGCCGGGTGCAGGAAGACCTCGCGGCCCAGAACCGCAGCTTCGCCGACGAGGGCACCACCGAGGAGGAAGCCCG
CGCCGATTACCGCAAGATCGCCGAGCGTCGCGTGCGCCTCGGCCTGGTGCTTGCGGAAATCGGTGAGCGCAACAATATCC
AGGTTTCTGAAGACGAGGTGACGCGCGCGGTTGTGGAACGGGCCCGCCAGTTCCCCGGCCAGGAGCAGCAGGTGTGGGAA
TATTACCGCCGCACCCCCGAAGCCCTGGCCTCCGTTCGCGCCCCCCTGTTCGAGGAGAAGGTCGTTGATTTCCTCCTGGA
GCTCGCCAACGTGACCGAGAAGACGGTGACGCGGGAAGAGCTCTACAAGGAGGAAGAGGACGACGAGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCACCGTGCGGCCTTTGGCGGGATGCCGGGGGATCTGCGGGGCCGAACCGGTTTTGAATGTTTTCCGCGCCATGCGCGA
CAGGATGTGAAGGCAAGACG

Downstream 100 bases:

>100_bases
GGGCCAAAGTCCGCCTTCGTCCTGCGACGATATTGCGCGGCACGCCCCCCGGGGCGTGCCATCGCCCGCGCCCCGAGGAC
TGACGATGCGTGATCCTGTC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MQVTETQADGLKRAFRVVVSAADLGAKADAKLAELKGQVKLNGFRPGKVPVAHLKRVYGKSVMSEVIEQTVNETNGKIVE
EHGFKLALQPKVKLPEEDPQAQGLLEGGKDLAYDLEIEILPKIELGNFKDISVEKLVVEVSDAEVDETIQRIADANRPFV
TREGGYAENGDRVTIDFTGYVDGEKFPGGEGQDIDVLLGSNGFIPGFEEQLLGVYAGDNRTLNVTFPEAYAAKELAGKAA
TFEVTVKSVAAPGPLTLDDEFAKTLGQESLEKLKEMVRARIASEHAGAARQKVKRALLDALDTTHQFAVPEGLVEQEFFG
VWSRVQEDLAAQNRSFADEGTTEEEARADYRKIAERRVRLGLVLAEIGERNNIQVSEDEVTRAVVERARQFPGQEQQVWE
YYRRTPEALASVRAPLFEEKVVDFLLELANVTEKTVTREELYKEEEDDEKAA

Sequences:

>Translated_452_residues
MQVTETQADGLKRAFRVVVSAADLGAKADAKLAELKGQVKLNGFRPGKVPVAHLKRVYGKSVMSEVIEQTVNETNGKIVE
EHGFKLALQPKVKLPEEDPQAQGLLEGGKDLAYDLEIEILPKIELGNFKDISVEKLVVEVSDAEVDETIQRIADANRPFV
TREGGYAENGDRVTIDFTGYVDGEKFPGGEGQDIDVLLGSNGFIPGFEEQLLGVYAGDNRTLNVTFPEAYAAKELAGKAA
TFEVTVKSVAAPGPLTLDDEFAKTLGQESLEKLKEMVRARIASEHAGAARQKVKRALLDALDTTHQFAVPEGLVEQEFFG
VWSRVQEDLAAQNRSFADEGTTEEEARADYRKIAERRVRLGLVLAEIGERNNIQVSEDEVTRAVVERARQFPGQEQQVWE
YYRRTPEALASVRAPLFEEKVVDFLLELANVTEKTVTREELYKEEEDDEKAA
>Mature_452_residues
MQVTETQADGLKRAFRVVVSAADLGAKADAKLAELKGQVKLNGFRPGKVPVAHLKRVYGKSVMSEVIEQTVNETNGKIVE
EHGFKLALQPKVKLPEEDPQAQGLLEGGKDLAYDLEIEILPKIELGNFKDISVEKLVVEVSDAEVDETIQRIADANRPFV
TREGGYAENGDRVTIDFTGYVDGEKFPGGEGQDIDVLLGSNGFIPGFEEQLLGVYAGDNRTLNVTFPEAYAAKELAGKAA
TFEVTVKSVAAPGPLTLDDEFAKTLGQESLEKLKEMVRARIASEHAGAARQKVKRALLDALDTTHQFAVPEGLVEQEFFG
VWSRVQEDLAAQNRSFADEGTTEEEARADYRKIAERRVRLGLVLAEIGERNNIQVSEDEVTRAVVERARQFPGQEQQVWE
YYRRTPEALASVRAPLFEEKVVDFLLELANVTEKTVTREELYKEEEDDEKAA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=447, Percent_Identity=32.4384787472036, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_XANP2 (A7ILC5)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001418475.1
- ProteinModelPortal:   A7ILC5
- SMR:   A7ILC5
- STRING:   A7ILC5
- GeneID:   5422559
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3590
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   XAUT78245:XAUT_3590-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 50039; Mature: 50039

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTETQADGLKRAFRVVVSAADLGAKADAKLAELKGQVKLNGFRPGKVPVAHLKRVYGK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCCCCHHHHHHHHHH
SVMSEVIEQTVNETNGKIVEEHGFKLALQPKVKLPEEDPQAQGLLEGGKDLAYDLEIEIL
HHHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEEEEE
PKIELGNFKDISVEKLVVEVSDAEVDETIQRIADANRPFVTREGGYAENGDRVTIDFTGY
CCEECCCCCCCCHHHEEEEECCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEE
VDGEKFPGGEGQDIDVLLGSNGFIPGFEEQLLGVYAGDNRTLNVTFPEAYAAKELAGKAA
ECCCCCCCCCCCEEEEEECCCCCCCCHHHHHEEEEECCCEEEEEECCHHHHHHHHHCCCE
TFEVTVKSVAAPGPLTLDDEFAKTLGQESLEKLKEMVRARIASEHAGAARQKVKRALLDA
EEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDTTHQFAVPEGLVEQEFFGVWSRVQEDLAAQNRSFADEGTTEEEARADYRKIAERRVRL
HHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GLVLAEIGERNNIQVSEDEVTRAVVERARQFPGQEQQVWEYYRRTPEALASVRAPLFEEK
HHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHCCHHHHH
VVDFLLELANVTEKTVTREELYKEEEDDEKAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQVTETQADGLKRAFRVVVSAADLGAKADAKLAELKGQVKLNGFRPGKVPVAHLKRVYGK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCCCCHHHHHHHHHH
SVMSEVIEQTVNETNGKIVEEHGFKLALQPKVKLPEEDPQAQGLLEGGKDLAYDLEIEIL
HHHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEEEEE
PKIELGNFKDISVEKLVVEVSDAEVDETIQRIADANRPFVTREGGYAENGDRVTIDFTGY
CCEECCCCCCCCHHHEEEEECCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEE
VDGEKFPGGEGQDIDVLLGSNGFIPGFEEQLLGVYAGDNRTLNVTFPEAYAAKELAGKAA
ECCCCCCCCCCCEEEEEECCCCCCCCHHHHHEEEEECCCEEEEEECCHHHHHHHHHCCCE
TFEVTVKSVAAPGPLTLDDEFAKTLGQESLEKLKEMVRARIASEHAGAARQKVKRALLDA
EEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDTTHQFAVPEGLVEQEFFGVWSRVQEDLAAQNRSFADEGTTEEEARADYRKIAERRVRL
HHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GLVLAEIGERNNIQVSEDEVTRAVVERARQFPGQEQQVWEYYRRTPEALASVRAPLFEEK
HHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHCCHHHHH
VVDFLLELANVTEKTVTREELYKEEEDDEKAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA