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The map label for this gene is folB [H]

Identifier: 154247457

GI number: 154247457

Start: 3937330

End: 3937767

Strand: Reverse

Name: folB [H]

Synonym: Xaut_3529

Alternate gene names: 154247457

Gene position: 3937767-3937330 (Counterclockwise)

Preceding gene: 154247458

Following gene: 154247456

Centisome position: 74.17

GC content: 69.18

Gene sequence:

>438_bases
ATGACGTCCGACGACACCCCTTCCCTCGCCGAAGCGCTGGCTGAAACCGAAGCCGGGACGCGCACCCGCCCGCACAACAC
GGACCGGCTGTTCCTGCGTGCCCTGCCCTTCTATGCCCGGCACGGCCTGTTCGAGGCCGAGCGCGAACTGGGCCAGCGCT
TCGTGGTGGACGTGGACTGCTGGCTCGACACCCGCCCCGCCGCCTGGGCCGACGATGCCGCCCTCACCGTCTCCTACCAG
CAGGTCTACGAGCATGTGTCGGCGGTGGTGACCGACGATCCGGTCCGCCTCATCGAGACCCTGGCCGAACGCATCGCCAC
GCGCATCCTCGACCATTTCGAGACCGTGGAGCAGGTGCGGGTGGTGGTGCACAAGCCCGGCGCGCCGATCACCGGCGTGT
TCGGCGACGTGGGCATCGAGATCATCCGCTCCCGCTAG

Upstream 100 bases:

>100_bases
ACAATCCCCGTGGAGGTGAAGCTCCGTTGAAAGGCGGGGCCGAAACCAATAGGAAGGCACATCGTTCAAGGCTGGCGGCC
CGCCGGCGCGTGAGACCCAT

Downstream 100 bases:

>100_bases
ATTTCGGCTCCCGCGCAAGGGGCGGAACGACGCGCCCCGCTTTCGCGCTCCGCTGCATTGCGTCATAAAGCAGCCGGCGG
GGGCGTCCGCCGGACCAGCA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MTSDDTPSLAEALAETEAGTRTRPHNTDRLFLRALPFYARHGLFEAERELGQRFVVDVDCWLDTRPAAWADDAALTVSYQ
QVYEHVSAVVTDDPVRLIETLAERIATRILDHFETVEQVRVVVHKPGAPITGVFGDVGIEIIRSR

Sequences:

>Translated_145_residues
MTSDDTPSLAEALAETEAGTRTRPHNTDRLFLRALPFYARHGLFEAERELGQRFVVDVDCWLDTRPAAWADDAALTVSYQ
QVYEHVSAVVTDDPVRLIETLAERIATRILDHFETVEQVRVVVHKPGAPITGVFGDVGIEIIRSR
>Mature_144_residues
TSDDTPSLAEALAETEAGTRTRPHNTDRLFLRALPFYARHGLFEAERELGQRFVVDVDCWLDTRPAAWADDAALTVSYQQ
VYEHVSAVVTDDPVRLIETLAERIATRILDHFETVEQVRVVVHKPGAPITGVFGDVGIEIIRSR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 16257; Mature: 16126

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDDTPSLAEALAETEAGTRTRPHNTDRLFLRALPFYARHGLFEAERELGQRFVVDVDC
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCEEEEEEEC
WLDTRPAAWADDAALTVSYQQVYEHVSAVVTDDPVRLIETLAERIATRILDHFETVEQVR
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVHKPGAPITGVFGDVGIEIIRSR
HHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TSDDTPSLAEALAETEAGTRTRPHNTDRLFLRALPFYARHGLFEAERELGQRFVVDVDC
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCEEEEEEEC
WLDTRPAAWADDAALTVSYQQVYEHVSAVVTDDPVRLIETLAERIATRILDHFETVEQVR
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVHKPGAPITGVFGDVGIEIIRSR
HHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]