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The map label for this gene is fbp2

Identifier: 154247456

GI number: 154247456

Start: 3936228

End: 3937217

Strand: Reverse

Name: fbp2

Synonym: Xaut_3528

Alternate gene names: 154247456

Gene position: 3937217-3936228 (Counterclockwise)

Preceding gene: 154247457

Following gene: 154247455

Centisome position: 74.16

GC content: 67.98

Gene sequence:

>990_bases
GTGAGCGAGTTGGTGACCTTGAAGACCTACCTCGGGACCTGGGCCGGCGCTGACACGGGCCGCACGGCGGTCGCGCAGGC
CGTGACCGCCATCGCCGAGGCCGGCGTAGGCATCGCCGATCTCGTTGCCCGCGGGCCGCTCGAAGAGGGCCTCGCTTCCA
TTCGCGGCGTCGATCCCAACGCCGGCGGCGACGCCCAGAAGGAACTGGACGTGGTGGCCGAGGAGCGCATCAAGGCCGCC
CTCCTGCCCACCCCCACCGCCTTCCTCGCCTCCGAGGAGAGCGAGGAGCTGATCCCGCTGAACCCGGACGGCCGCCTCGT
GATCGCGGTGGACCCGCTGGACGGCTCCTCCAACATCGACACCAACGTGTCGGTGGGCACCATCTATTCCATCCTGCCCT
ATGACGCGGCCGTGCACACCGATCCGGTATCGGCGGTGATGCGGCCGGGCGTGAACCAGGTGGCCTCGGGCTTCCTGGCC
TATGGCCCTGCCACCATCCTCGTCGCCACCTTCGGGGAAGGCACGCAGGTGTTCGTCCACGACCGGCAGACCGGCGAGTT
CGTGCTGGCCCGCACCAATGTGGAGATCCCGGCCGAGACCAAGGAATACGGCGTCAACCAGTCCAACGTGCGCCACTGGG
CGGAGCCCATGAGCGCCTATATCGCCGACTGCCTCGCCGGCAAAGACGGGCCCCGCGGCAAGGATTTCAACATGCGCTGG
GTGGGCTCCATGGTGGCCGACGCCTTCCGCATTTTCACCCGCGGCGGCGTCTATGTGTATCCCGGCGACAAGCGCAAGGG
CTACGAGAACGGCCGCCTGCGCCTGATCTACGAGGCCAACCCGGTGGCCTTCCTCACCGAGCAGGCCAAGGGCGCCGCCA
CCGACGGCAAGACCCGCATCCTCGACATCCAGCCCCACCACATCCACCAGCGCATCCCGCTGGTGTTCGGCTCCAAGGCC
GAGGTGGAGAAGATCGCGTCGTATTACTGA

Upstream 100 bases:

>100_bases
GCGCAAGGGGCGGAACGACGCGCCCCGCTTTCGCGCTCCGCTGCATTGCGTCATAAAGCAGCCGGCGGGGGCGTCCGCCG
GACCAGCATGGGAGTGCGCG

Downstream 100 bases:

>100_bases
GCGGCGTAGACCGTTGCTTTCATCCCTCATGCCCCGGACAAGCCGGGGCATGAGGTGACCCTTGGCCCTTCAGGGCACCC
CTTGACCTGACCCAGAAAAA

Product: inositol phosphatase/fructose-16-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSELVTLKTYLGTWAGADTGRTAVAQAVTAIAEAGVGIADLVARGPLEEGLASIRGVDPNAGGDAQKELDVVAEERIKAA
LLPTPTAFLASEESEELIPLNPDGRLVIAVDPLDGSSNIDTNVSVGTIYSILPYDAAVHTDPVSAVMRPGVNQVASGFLA
YGPATILVATFGEGTQVFVHDRQTGEFVLARTNVEIPAETKEYGVNQSNVRHWAEPMSAYIADCLAGKDGPRGKDFNMRW
VGSMVADAFRIFTRGGVYVYPGDKRKGYENGRLRLIYEANPVAFLTEQAKGAATDGKTRILDIQPHHIHQRIPLVFGSKA
EVEKIASYY

Sequences:

>Translated_329_residues
MSELVTLKTYLGTWAGADTGRTAVAQAVTAIAEAGVGIADLVARGPLEEGLASIRGVDPNAGGDAQKELDVVAEERIKAA
LLPTPTAFLASEESEELIPLNPDGRLVIAVDPLDGSSNIDTNVSVGTIYSILPYDAAVHTDPVSAVMRPGVNQVASGFLA
YGPATILVATFGEGTQVFVHDRQTGEFVLARTNVEIPAETKEYGVNQSNVRHWAEPMSAYIADCLAGKDGPRGKDFNMRW
VGSMVADAFRIFTRGGVYVYPGDKRKGYENGRLRLIYEANPVAFLTEQAKGAATDGKTRILDIQPHHIHQRIPLVFGSKA
EVEKIASYY
>Mature_328_residues
SELVTLKTYLGTWAGADTGRTAVAQAVTAIAEAGVGIADLVARGPLEEGLASIRGVDPNAGGDAQKELDVVAEERIKAAL
LPTPTAFLASEESEELIPLNPDGRLVIAVDPLDGSSNIDTNVSVGTIYSILPYDAAVHTDPVSAVMRPGVNQVASGFLAY
GPATILVATFGEGTQVFVHDRQTGEFVLARTNVEIPAETKEYGVNQSNVRHWAEPMSAYIADCLAGKDGPRGKDFNMRWV
GSMVADAFRIFTRGGVYVYPGDKRKGYENGRLRLIYEANPVAFLTEQAKGAATDGKTRILDIQPHHIHQRIPLVFGSKAE
VEKIASYY

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=318, Percent_Identity=36.4779874213836, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI16579888, Length=318, Percent_Identity=36.4779874213836, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI22907028, Length=329, Percent_Identity=34.0425531914894, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1790679, Length=297, Percent_Identity=39.7306397306397, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17508131, Length=294, Percent_Identity=39.4557823129252, Blast_Score=197, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6323409, Length=276, Percent_Identity=41.6666666666667, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI45550998, Length=287, Percent_Identity=39.3728222996516, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19921562, Length=287, Percent_Identity=39.3728222996516, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16A2_XANP2 (A7IL64)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001418414.1
- ProteinModelPortal:   A7IL64
- SMR:   A7IL64
- STRING:   A7IL64
- GeneID:   5421277
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3528
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- ProtClustDB:   CLSK980045
- BioCyc:   XAUT78245:XAUT_3528-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 35230; Mature: 35099

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00124 FBPASE

Important sites: BINDING 206-206

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELVTLKTYLGTWAGADTGRTAVAQAVTAIAEAGVGIADLVARGPLEEGLASIRGVDPN
CCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHCCCCCC
AGGDAQKELDVVAEERIKAALLPTPTAFLASEESEELIPLNPDGRLVIAVDPLDGSSNID
CCCCHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCCEEEECCCCEEEEEEECCCCCCCCC
TNVSVGTIYSILPYDAAVHTDPVSAVMRPGVNQVASGFLAYGPATILVATFGEGTQVFVH
CCCCHHHEEEECCCCCCCCCCHHHHHHCCCHHHHHCCHHHCCCEEEEEEECCCCCEEEEE
DRQTGEFVLARTNVEIPAETKEYGVNQSNVRHWAEPMSAYIADCLAGKDGPRGKDFNMRW
ECCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VGSMVADAFRIFTRGGVYVYPGDKRKGYENGRLRLIYEANPVAFLTEQAKGAATDGKTRI
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCEEE
LDIQPHHIHQRIPLVFGSKAEVEKIASYY
EECCCHHHHHCCCEEECCHHHHHHHHHCC
>Mature Secondary Structure 
SELVTLKTYLGTWAGADTGRTAVAQAVTAIAEAGVGIADLVARGPLEEGLASIRGVDPN
CCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHCCCCCC
AGGDAQKELDVVAEERIKAALLPTPTAFLASEESEELIPLNPDGRLVIAVDPLDGSSNID
CCCCHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCCEEEECCCCEEEEEEECCCCCCCCC
TNVSVGTIYSILPYDAAVHTDPVSAVMRPGVNQVASGFLAYGPATILVATFGEGTQVFVH
CCCCHHHEEEECCCCCCCCCCHHHHHHCCCHHHHHCCHHHCCCEEEEEEECCCCCEEEEE
DRQTGEFVLARTNVEIPAETKEYGVNQSNVRHWAEPMSAYIADCLAGKDGPRGKDFNMRW
ECCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
VGSMVADAFRIFTRGGVYVYPGDKRKGYENGRLRLIYEANPVAFLTEQAKGAATDGKTRI
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCEEE
LDIQPHHIHQRIPLVFGSKAEVEKIASYY
EECCCHHHHHCCCEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA