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The map label for this gene is yiaV [H]

Identifier: 154247342

GI number: 154247342

Start: 3806593

End: 3807534

Strand: Reverse

Name: yiaV [H]

Synonym: Xaut_3414

Alternate gene names: 154247342

Gene position: 3807534-3806593 (Counterclockwise)

Preceding gene: 154247343

Following gene: 154247341

Centisome position: 71.72

GC content: 63.8

Gene sequence:

>942_bases
ATGATCGTCCTGCTGCTGAACCTCTATATCGCGATCCTCGTCACCCTGATCTGGCTGAAGATCATTCCCAACACCCTGCT
CTGGAAACTGTCCCCCATCCCCGTGCTGGTGCTGCTGAACGTCGCGCTCTTCATACCCATGGGATGGGGTGCCCCGACAG
GCGGCGCCATCATCGGGCGGCACTCCGTTTCCATCGTTCCCGACGTGAGCGGAGAAGTGATCGAGGTCACGGTCTCGCCC
AACGTGTCCCTCAAGGCCGGCGATGTCCTGTTCCGCATCGATCCCACGCCCTACTCAGCCCAGCTGCGCGCGCTGGAAGC
GCAGCTGAAGCTCGCCGAGACCCGCCTTGCCCAGATGACCGAGCTGGCCCGGAAGCAGGCGGCGCCGGAATTCAACGTCG
AAGAGCGTCAGAGCGAGGTGGACCGGCTCAGGGCGCAGGTCGATGGTGCCCGCTGGAACCTCGACAAGACGATCGTCCGC
GCTCCGGCGGATGGCTATGTCACCAATCTGGCGCTGCGCAAGGGCGCGCGCGTGTCGAACCTGGCGGTGTCTCCGGTGAT
GGCCTTCATCGATACCACCGAGGCGGTCACCATCATTCAGGTTCCGCAGAACTATGCACGCTATATCGAACCGGGGCAGA
AGGTGGAGATCACCTTCAAGCTTCTGCCCGGGCAGGTCTTTACCGGTCGTGTCGAGAGCGTGCTCCAGGCCATCGCACCC
GGACAGACCGCGCCGTCCGGTTCCGCCGCCGAGAACCGGGACCTGACGCCCGAGCCGTTCGTTGTACGCGCGACGCTCGA
CGACCCGACGCTGGAGGACCGCCTGCCGGCCGGCAGCGTGGGCAGCGCGGCGATCTATACCGAACACGTGAAGCTTAGCC
ACGTGATCCGTCAGGTCATACTGCGTCAACAGGCGATTCTGAACTACATCTGGCCCTATTGA

Upstream 100 bases:

>100_bases
GGGTGACGCTCCTCTGCGGCTTCGTGCTGTGGCCCATTGCGCTCATCTGGGCCTATGTGGACGTGCCCGCCCGGCCGGAG
CGCAAACAGGAGGCGGCGCA

Downstream 100 bases:

>100_bases
GGGTACCGTCAGGAATGCGTTCGCCTTGCTGCAGGTATCACGAATAGGGAGGAAGCCATGCGGACAAAAGAGCGGTCTGC
GCATGCGGCAACCTTCGCCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MIVLLLNLYIAILVTLIWLKIIPNTLLWKLSPIPVLVLLNVALFIPMGWGAPTGGAIIGRHSVSIVPDVSGEVIEVTVSP
NVSLKAGDVLFRIDPTPYSAQLRALEAQLKLAETRLAQMTELARKQAAPEFNVEERQSEVDRLRAQVDGARWNLDKTIVR
APADGYVTNLALRKGARVSNLAVSPVMAFIDTTEAVTIIQVPQNYARYIEPGQKVEITFKLLPGQVFTGRVESVLQAIAP
GQTAPSGSAAENRDLTPEPFVVRATLDDPTLEDRLPAGSVGSAAIYTEHVKLSHVIRQVILRQQAILNYIWPY

Sequences:

>Translated_313_residues
MIVLLLNLYIAILVTLIWLKIIPNTLLWKLSPIPVLVLLNVALFIPMGWGAPTGGAIIGRHSVSIVPDVSGEVIEVTVSP
NVSLKAGDVLFRIDPTPYSAQLRALEAQLKLAETRLAQMTELARKQAAPEFNVEERQSEVDRLRAQVDGARWNLDKTIVR
APADGYVTNLALRKGARVSNLAVSPVMAFIDTTEAVTIIQVPQNYARYIEPGQKVEITFKLLPGQVFTGRVESVLQAIAP
GQTAPSGSAAENRDLTPEPFVVRATLDDPTLEDRLPAGSVGSAAIYTEHVKLSHVIRQVILRQQAILNYIWPY
>Mature_313_residues
MIVLLLNLYIAILVTLIWLKIIPNTLLWKLSPIPVLVLLNVALFIPMGWGAPTGGAIIGRHSVSIVPDVSGEVIEVTVSP
NVSLKAGDVLFRIDPTPYSAQLRALEAQLKLAETRLAQMTELARKQAAPEFNVEERQSEVDRLRAQVDGARWNLDKTIVR
APADGYVTNLALRKGARVSNLAVSPVMAFIDTTEAVTIIQVPQNYARYIEPGQKVEITFKLLPGQVFTGRVESVLQAIAP
GQTAPSGSAAENRDLTPEPFVVRATLDDPTLEDRLPAGSVGSAAIYTEHVKLSHVIRQVILRQQAILNYIWPY

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=314, Percent_Identity=30.5732484076433, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1790024, Length=340, Percent_Identity=27.9411764705882, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87081951, Length=190, Percent_Identity=33.1578947368421, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789637, Length=288, Percent_Identity=27.4305555555556, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790519, Length=105, Percent_Identity=34.2857142857143, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 34277; Mature: 34277

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLLLNLYIAILVTLIWLKIIPNTLLWKLSPIPVLVLLNVALFIPMGWGAPTGGAIIGR
CEEEHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHEECCCCCCCCCEEEEC
HSVSIVPDVSGEVIEVTVSPNVSLKAGDVLFRIDPTPYSAQLRALEAQLKLAETRLAQMT
CCEEEECCCCCCEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ELARKQAAPEFNVEERQSEVDRLRAQVDGARWNLDKTIVRAPADGYVTNLALRKGARVSN
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEECCCHHEEECCCCCHHHHHHHHCCCCHHH
LAVSPVMAFIDTTEAVTIIQVPQNYARYIEPGQKVEITFKLLPGQVFTGRVESVLQAIAP
HHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCC
GQTAPSGSAAENRDLTPEPFVVRATLDDPTLEDRLPAGSVGSAAIYTEHVKLSHVIRQVI
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCHHEEHHHHHHHHHHHHH
LRQQAILNYIWPY
HHHHHHHHHHCCC
>Mature Secondary Structure
MIVLLLNLYIAILVTLIWLKIIPNTLLWKLSPIPVLVLLNVALFIPMGWGAPTGGAIIGR
CEEEHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHHHHEECCCCCCCCCEEEEC
HSVSIVPDVSGEVIEVTVSPNVSLKAGDVLFRIDPTPYSAQLRALEAQLKLAETRLAQMT
CCEEEECCCCCCEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ELARKQAAPEFNVEERQSEVDRLRAQVDGARWNLDKTIVRAPADGYVTNLALRKGARVSN
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEECCCHHEEECCCCCHHHHHHHHCCCCHHH
LAVSPVMAFIDTTEAVTIIQVPQNYARYIEPGQKVEITFKLLPGQVFTGRVESVLQAIAP
HHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCC
GQTAPSGSAAENRDLTPEPFVVRATLDDPTLEDRLPAGSVGSAAIYTEHVKLSHVIRQVI
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCHHEEHHHHHHHHHHHHH
LRQQAILNYIWPY
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]