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The map label for this gene is pcoA [H]

Identifier: 154247336

GI number: 154247336

Start: 3796865

End: 3798415

Strand: Direct

Name: pcoA [H]

Synonym: Xaut_3408

Alternate gene names: 154247336

Gene position: 3796865-3798415 (Clockwise)

Preceding gene: 154247335

Following gene: 154247337

Centisome position: 71.52

GC content: 69.57

Gene sequence:

>1551_bases
ATGACCCGACCCATGTTCCAGTCCGCTCCCTCGCGCCGCACCGTCCTTGCCGGCGGCGCGGCACTCGGCGCCCTCGCCCT
TTCCGGCGGCTGGCAGCGCGCCCTTGCCGCCCCGCTGCTCACGGTGGAAAGCCTGACCCTCGACGTGAACGGCAAGGCGG
CGAAGGTCTTCGCCGTGAAGGGCCCTTCCGGCGAAGGCCTGTTCGCGAAAGAAGGCGACCGGCTCACCGGCGCGGTGCTC
AACGCCTCGCAGAGCCCGGCGGTGATGCACTGGCACGGCCAGATCTTTGCCCCGCCGGACCAGGACCGCGCCCGCCCCAA
TGGCGGCGAGCTTGCCCCCGGGGGCATTGATCAGGTGGATTTCCGGCTCACCCCGGGCACCCACTGGATGCACTCCCACA
CCTTGAGCGAGCAGCAATTGCTCGCCGCGCCGCTGGTCACCCGCGAGGCGGATGCGGGCGATGTCCAGGACGTGGTGGTG
ATGCTGCACGATTTCTCCTTCCGCAGCCCGGAGGAGATCCTGGCCGAGCTCGGCGGCGCGAACACGCACGGCGGCCACGG
TGGTCACGGCATGGGCCAGCAGATGCAAGGCATGCCGGGCATGGCGATGCCGGGAATGGACCATTCCGGCCACGGCATGG
GCGCAATGGGGGCAGGGCAGGGCGCTATGCCGGGCGGCGCCATGCACGGCGGGGGCATGCAGGGAGGCGGCATGCCAGGT
GGCGGCATGCCGGGCGGCGGCATGATGGTGCACGCCAATGATGTTGCCTACGACGCCTTCCTCGCCAACCGCCGCACCCT
CGCCGATCCCGATGTGGTGCAGGTGGAGAAGGGCGGCCGGGTGCGGCTGCGCATCATCAATGGCGGCACTGCCACCGCCT
TCTTCATCACCGTGCCCGGCCTGAAGGCGACCTGCATCGCCGTCGACGGTACGCCTTGCGTCCCGTTGGCGGCGGATGCC
TTTCCGCTCGCCCAGGGCCAGCGCATCGACCTCCTCGCGGAGATCCCCGCGAGCGGCGGCGCCTTTCCGGTGCTGGCGCA
GGTGGAAGCCTCACCCCGCCGCACCGGCCTCGTGCTCGCGACAGCGGGCGCTGCCATCGCCCGTGTTGGGGAGATGGCCG
ACAGGCCGCAGGGCCTTCTCGACCTCGCTTTCGAGGGGCAGCTTTCCGCCTTGAAGCCTCTCGCGGTGCGGCGGGCGGAC
AAGGTCTTCCCCATCATGCTGGGGGAAGAGCCAGGCTACCGCTGGACCATCAACGGGCGCATCCATGGGGAGGACGTGCC
CTTCAGCGTGCAGCAGGGCGAGCGGGTGGAGATGACCTTCCTGAACCCCACCGGCATGAGCCATCCCATGCACCTGCACG
GTCATCACTTCCAGGTGGTGGGCATCGGCGGGCGCCGTTTTTCAGGGGCGCTGCGCGACACAGTGATGGTGCCACCGCAC
ACGCCGGTGACCATCGCCTTCGATGCGGGGCAGAAGGGCGAGTGGTTCCTGCACTGCCACCACCTCTACCACATGGCCAC
CGGCATGATGGCCGTGGTGAAGGTGACCTGA

Upstream 100 bases:

>100_bases
TCCGCGCCCGACGGTGCCTCCGCGCAGGCCAAATACTGAAGACCGACCGCCCCCCTTCGCTTCGCCCCGTCTGCCCGGCG
ACGAGCCAAAGAGACCGACC

Downstream 100 bases:

>100_bases
TGCCGAAGGCGGAGGGCAAAAGGCGGTTCCAACTCACCATGGGTCATCAGAGGCGGCCGATCCCTGCTCCGTGGCCGTCC
CCGGCCCGGGAACGGAGGGT

Product: multicopper oxidase type 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTRPMFQSAPSRRTVLAGGAALGALALSGGWQRALAAPLLTVESLTLDVNGKAAKVFAVKGPSGEGLFAKEGDRLTGAVL
NASQSPAVMHWHGQIFAPPDQDRARPNGGELAPGGIDQVDFRLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVV
MLHDFSFRSPEEILAELGGANTHGGHGGHGMGQQMQGMPGMAMPGMDHSGHGMGAMGAGQGAMPGGAMHGGGMQGGGMPG
GGMPGGGMMVHANDVAYDAFLANRRTLADPDVVQVEKGGRVRLRIINGGTATAFFITVPGLKATCIAVDGTPCVPLAADA
FPLAQGQRIDLLAEIPASGGAFPVLAQVEASPRRTGLVLATAGAAIARVGEMADRPQGLLDLAFEGQLSALKPLAVRRAD
KVFPIMLGEEPGYRWTINGRIHGEDVPFSVQQGERVEMTFLNPTGMSHPMHLHGHHFQVVGIGGRRFSGALRDTVMVPPH
TPVTIAFDAGQKGEWFLHCHHLYHMATGMMAVVKVT

Sequences:

>Translated_516_residues
MTRPMFQSAPSRRTVLAGGAALGALALSGGWQRALAAPLLTVESLTLDVNGKAAKVFAVKGPSGEGLFAKEGDRLTGAVL
NASQSPAVMHWHGQIFAPPDQDRARPNGGELAPGGIDQVDFRLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVV
MLHDFSFRSPEEILAELGGANTHGGHGGHGMGQQMQGMPGMAMPGMDHSGHGMGAMGAGQGAMPGGAMHGGGMQGGGMPG
GGMPGGGMMVHANDVAYDAFLANRRTLADPDVVQVEKGGRVRLRIINGGTATAFFITVPGLKATCIAVDGTPCVPLAADA
FPLAQGQRIDLLAEIPASGGAFPVLAQVEASPRRTGLVLATAGAAIARVGEMADRPQGLLDLAFEGQLSALKPLAVRRAD
KVFPIMLGEEPGYRWTINGRIHGEDVPFSVQQGERVEMTFLNPTGMSHPMHLHGHHFQVVGIGGRRFSGALRDTVMVPPH
TPVTIAFDAGQKGEWFLHCHHLYHMATGMMAVVKVT
>Mature_515_residues
TRPMFQSAPSRRTVLAGGAALGALALSGGWQRALAAPLLTVESLTLDVNGKAAKVFAVKGPSGEGLFAKEGDRLTGAVLN
ASQSPAVMHWHGQIFAPPDQDRARPNGGELAPGGIDQVDFRLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVVM
LHDFSFRSPEEILAELGGANTHGGHGGHGMGQQMQGMPGMAMPGMDHSGHGMGAMGAGQGAMPGGAMHGGGMQGGGMPGG
GMPGGGMMVHANDVAYDAFLANRRTLADPDVVQVEKGGRVRLRIINGGTATAFFITVPGLKATCIAVDGTPCVPLAADAF
PLAQGQRIDLLAEIPASGGAFPVLAQVEASPRRTGLVLATAGAAIARVGEMADRPQGLLDLAFEGQLSALKPLAVRRADK
VFPIMLGEEPGYRWTINGRIHGEDVPFSVQQGERVEMTFLNPTGMSHPMHLHGHHFQVVGIGGRRFSGALRDTVMVPPHT
PVTIAFDAGQKGEWFLHCHHLYHMATGMMAVVKVT

Specific function: Required for the copper-inducible expression of copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 53899; Mature: 53767

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPMFQSAPSRRTVLAGGAALGALALSGGWQRALAAPLLTVESLTLDVNGKAAKVFAVK
CCCCCCCCCCCCEEEEECCHHHHHHHCCCCHHHHHHHHEEEEEEEEEEECCCEEEEEEEE
GPSGEGLFAKEGDRLTGAVLNASQSPAVMHWHGQIFAPPDQDRARPNGGELAPGGIDQVD
CCCCCCCEECCCCEEEEEEECCCCCCEEEEECCEEECCCCHHCCCCCCCCCCCCCCCEEE
FRLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVVMLHDFSFRSPEEILAELGGA
EEECCCCCEEECCCCCHHHHHHCCCEECCCCCCCHHHHHEEEECCCCCCHHHHHHHHCCC
NTHGGHGGHGMGQQMQGMPGMAMPGMDHSGHGMGAMGAGQGAMPGGAMHGGGMQGGGMPG
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGMPGGGMMVHANDVAYDAFLANRRTLADPDVVQVEKGGRVRLRIINGGTATAFFITVPG
CCCCCCCEEEEECCCEEEHHHHCCCCCCCCCEEEEECCCEEEEEEEECCCEEEEEEECCC
LKATCIAVDGTPCVPLAADAFPLAQGQRIDLLAEIPASGGAFPVLAQVEASPRRTGLVLA
CEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCEEEEE
TAGAAIARVGEMADRPQGLLDLAFEGQLSALKPLAVRRADKVFPIMLGEEPGYRWTINGR
ECCHHHHHHHHHHCCCCCEEEEEECCCCHHHCHHHHHCCCCEEEEEECCCCCCEEEECCE
IHGEDVPFSVQQGERVEMTFLNPTGMSHPMHLHGHHFQVVGIGGRRFSGALRDTVMVPPH
EECCCCCEECCCCCEEEEEEECCCCCCCCEEECCCEEEEEEECCCCCCCCHHCEEEECCC
TPVTIAFDAGQKGEWFLHCHHLYHMATGMMAVVKVT
CCEEEEECCCCCCCEEEEHHHHHHHHHCEEEEEEEC
>Mature Secondary Structure 
TRPMFQSAPSRRTVLAGGAALGALALSGGWQRALAAPLLTVESLTLDVNGKAAKVFAVK
CCCCCCCCCCCEEEEECCHHHHHHHCCCCHHHHHHHHEEEEEEEEEEECCCEEEEEEEE
GPSGEGLFAKEGDRLTGAVLNASQSPAVMHWHGQIFAPPDQDRARPNGGELAPGGIDQVD
CCCCCCCEECCCCEEEEEEECCCCCCEEEEECCEEECCCCHHCCCCCCCCCCCCCCCEEE
FRLTPGTHWMHSHTLSEQQLLAAPLVTREADAGDVQDVVVMLHDFSFRSPEEILAELGGA
EEECCCCCEEECCCCCHHHHHHCCCEECCCCCCCHHHHHEEEECCCCCCHHHHHHHHCCC
NTHGGHGGHGMGQQMQGMPGMAMPGMDHSGHGMGAMGAGQGAMPGGAMHGGGMQGGGMPG
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGMPGGGMMVHANDVAYDAFLANRRTLADPDVVQVEKGGRVRLRIINGGTATAFFITVPG
CCCCCCCEEEEECCCEEEHHHHCCCCCCCCCEEEEECCCEEEEEEEECCCEEEEEEECCC
LKATCIAVDGTPCVPLAADAFPLAQGQRIDLLAEIPASGGAFPVLAQVEASPRRTGLVLA
CEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCEEEEE
TAGAAIARVGEMADRPQGLLDLAFEGQLSALKPLAVRRADKVFPIMLGEEPGYRWTINGR
ECCHHHHHHHHHHCCCCCEEEEEECCCCHHHCHHHHHCCCCEEEEEECCCCCCEEEECCE
IHGEDVPFSVQQGERVEMTFLNPTGMSHPMHLHGHHFQVVGIGGRRFSGALRDTVMVPPH
EECCCCCEECCCCCEEEEEEECCCCCCCCEEECCCEEEEEEECCCCCCCCHHCEEEECCC
TPVTIAFDAGQKGEWFLHCHHLYHMATGMMAVVKVT
CCEEEEECCCCCCCEEEEHHHHHHHHHCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]