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The map label for this gene is nanR [H]

Identifier: 154247275

GI number: 154247275

Start: 3725714

End: 3726481

Strand: Reverse

Name: nanR [H]

Synonym: Xaut_3347

Alternate gene names: 154247275

Gene position: 3726481-3725714 (Counterclockwise)

Preceding gene: 154247281

Following gene: 154247274

Centisome position: 70.19

GC content: 70.31

Gene sequence:

>768_bases
GTGAGACAGGGAGTGCGGGCAAACCAGATGGAACCGACCTACGGCCAGATTGTCACCACCAGCGCCGCCAGCCAGATCGC
GGACCAGCTTCAGCAGGCGATCGTGGATGGCCGCCTCAAGGTGGATGAGCGCCTGCCGACTGAAGAGGAGCTGGCCGCCC
AGTTCGGCGTGTCGCGCCCCACCGTGCGCGAGGCGCTGAAGCGGCTGGCGGCGCGCCACCTCATCCGTTCGCGGCGCGGC
CCGACCGGCGGCACCTTCGTCACCGGGCCGTCGCCCGAGGACCTGGCGGCCAGCCTCGGCACCTCGGTCACGCTCATGGT
GGCGAGCGGCGGCATCACGCTTGAGGAGATGGCCACGGCCCGGCTGGAGATGGAGGCGGTGTGCTGCCGCCTCGCCGCGC
AGAACCGCACCGACGCGCATCTCGCGGCGCTGGAGGCGGAGATCGCCCTGCAGAAGAACGCCGCCGTCTCCGACCAGGAT
TTCTGCGCCTCCGATGTGCGTTTCCATCGCGCGGTGGTGGACGCCGCCGGCAACGCGCTGCTGCGCTTCCTCATGAACGC
GGTGGTGGAAGCCCTGATGCCGGTGAGCAACATGATCATCTTCCGCGTCCGCGACCGGAAGGAGATCGTCGGCCATCACG
AGCGCATGCTGGCGGCCCTGAGGGAGCGGGACGGCGAGGCCGCCGTCGAGGCCCTCGGCGGGCTCGTCCACTACATCCGC
GCGCAATATGCGAAGGCCGACGAGGCCCGCAAAGCCCCTCGCCGCTGA

Upstream 100 bases:

>100_bases
TCTTCGTCCGCGATCGGTCAAACTGAAAGCGCCCAATCCCCTATTTGTCAAACAAATAATTTTTAGGTTGATTTGACCGC
CCACATCTGAGACCAAGAAG

Downstream 100 bases:

>100_bases
GCCCTTACGCCGACAACTGCATCGGCGGTTTCACAGACAAGACCACAGGGAAACGTCGCATGAGCAACGAAACGTTTCGC
GCCCTCATGGCGCGAAAGAC

Product: regulatory protein GntR HTH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRQGVRANQMEPTYGQIVTTSAASQIADQLQQAIVDGRLKVDERLPTEEELAAQFGVSRPTVREALKRLAARHLIRSRRG
PTGGTFVTGPSPEDLAASLGTSVTLMVASGGITLEEMATARLEMEAVCCRLAAQNRTDAHLAALEAEIALQKNAAVSDQD
FCASDVRFHRAVVDAAGNALLRFLMNAVVEALMPVSNMIIFRVRDRKEIVGHHERMLAALRERDGEAAVEALGGLVHYIR
AQYAKADEARKAPRR

Sequences:

>Translated_255_residues
MRQGVRANQMEPTYGQIVTTSAASQIADQLQQAIVDGRLKVDERLPTEEELAAQFGVSRPTVREALKRLAARHLIRSRRG
PTGGTFVTGPSPEDLAASLGTSVTLMVASGGITLEEMATARLEMEAVCCRLAAQNRTDAHLAALEAEIALQKNAAVSDQD
FCASDVRFHRAVVDAAGNALLRFLMNAVVEALMPVSNMIIFRVRDRKEIVGHHERMLAALRERDGEAAVEALGGLVHYIR
AQYAKADEARKAPRR
>Mature_255_residues
MRQGVRANQMEPTYGQIVTTSAASQIADQLQQAIVDGRLKVDERLPTEEELAAQFGVSRPTVREALKRLAARHLIRSRRG
PTGGTFVTGPSPEDLAASLGTSVTLMVASGGITLEEMATARLEMEAVCCRLAAQNRTDAHLAALEAEIALQKNAAVSDQD
FCASDVRFHRAVVDAAGNALLRFLMNAVVEALMPVSNMIIFRVRDRKEIVGHHERMLAALRERDGEAAVEALGGLVHYIR
AQYAKADEARKAPRR

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786303, Length=175, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789621, Length=221, Percent_Identity=26.6968325791855, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI48994955, Length=234, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790032, Length=176, Percent_Identity=31.25, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27752; Mature: 27752

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQGVRANQMEPTYGQIVTTSAASQIADQLQQAIVDGRLKVDERLPTEEELAAQFGVSRP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHCCCCH
TVREALKRLAARHLIRSRRGPTGGTFVTGPSPEDLAASLGTSVTLMVASGGITLEEMATA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHH
RLEMEAVCCRLAAQNRTDAHLAALEAEIALQKNAAVSDQDFCASDVRFHRAVVDAAGNAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRFLMNAVVEALMPVSNMIIFRVRDRKEIVGHHERMLAALRERDGEAAVEALGGLVHYIR
HHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQYAKADEARKAPRR
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MRQGVRANQMEPTYGQIVTTSAASQIADQLQQAIVDGRLKVDERLPTEEELAAQFGVSRP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHCCCCH
TVREALKRLAARHLIRSRRGPTGGTFVTGPSPEDLAASLGTSVTLMVASGGITLEEMATA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHH
RLEMEAVCCRLAAQNRTDAHLAALEAEIALQKNAAVSDQDFCASDVRFHRAVVDAAGNAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRFLMNAVVEALMPVSNMIIFRVRDRKEIVGHHERMLAALRERDGEAAVEALGGLVHYIR
HHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQYAKADEARKAPRR
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA