Click here to switch to the map view.

The map label for this gene is cobM [H]

Identifier: 154247206

GI number: 154247206

Start: 3639426

End: 3640187

Strand: Reverse

Name: cobM [H]

Synonym: Xaut_3278

Alternate gene names: 154247206

Gene position: 3640187-3639426 (Counterclockwise)

Preceding gene: 154247207

Following gene: 154247204

Centisome position: 68.57

GC content: 71.0

Gene sequence:

>762_bases
GTGACCGTTCATTTCATCGGCGCGGGACCCGGCGCGGCGGACCTCATCACCGTGCGCGGGCGCGATCTCATCGCCCGCTG
CCCGGTCTGCCTCTATGCCGGCTCCATCGTCGCGCCGGAACTGCTGGACTACTGCCCGCCCGGCGCGCGCATCGTGGATA
CCGCCCCCCTCGACCTCGACCGGATCGAGGCCGAATATGTGCGCGCCTTCGCGGCGGGCGAGGATGTGGCGCGGCTGCAT
TCCGGCGACCTCTCGGTCTACAGCGCGGTGGCCGAGCAGATGCGCCGGCTCGACCGGCTGTCCATCCCCTATACGCTGAC
GCCCGGCGTGCCGGCCTTCGCGGCGGCGGCAGCGCTGCTGAAGCGGGAGTTCACCGTGCCCGAGGTGGCCCAGAGCCTCG
TCATCACCCGCGTCTCGGGCCGCGCCTCCGCCATGCCTGAGAGCGAAAAGCTTAAAGCCTTCGCTGCCACGGGGGCGACC
CTCGCCATTCATCTGGCCATCCATGCCCTCGACAAGGTGGTGGCGGAACTGACCCCGGTGCTCGGTACCGACTGCCCGGT
GGCGGTGGTGGCCAAGGCCTCCTGGCCGGACGGGCGCGTCGTCACCGGGACCCTCGGTGACATCGCCGGCCAGCTTGAGG
CCGACCCCATCCCGCGCACGGCGCTCATTCTGGTGGGGCGGGCGCTGGCGGCGCAGGATTTCCGCGAGAGCGCGCTCTAC
GACACCGCCTATGTCCGCCGCTTTCGCGGGGGCGGAGAATGA

Upstream 100 bases:

>100_bases
CGGCGCTTGCCGCCGGCGGTGCCCGGGCGCGCCTTCTTGGGCCGCGCCTTGCGCTCGGCCCCGTCACCTGCGCCCTGGCC
CGGCGGGAGGAAGAAGAAGC

Downstream 100 bases:

>100_bases
GGGACGGCTCAGGCCTGCGCGGGGGCGAAGGGGGCGCGGCCCATGAGCGTGCCGTCGCGGTCGAACACGACGATCTCCAG
CGCTACGTCGGCCCGGCCGA

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSIVAPELLDYCPPGARIVDTAPLDLDRIEAEYVRAFAAGEDVARLH
SGDLSVYSAVAEQMRRLDRLSIPYTLTPGVPAFAAAAALLKREFTVPEVAQSLVITRVSGRASAMPESEKLKAFAATGAT
LAIHLAIHALDKVVAELTPVLGTDCPVAVVAKASWPDGRVVTGTLGDIAGQLEADPIPRTALILVGRALAAQDFRESALY
DTAYVRRFRGGGE

Sequences:

>Translated_253_residues
MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSIVAPELLDYCPPGARIVDTAPLDLDRIEAEYVRAFAAGEDVARLH
SGDLSVYSAVAEQMRRLDRLSIPYTLTPGVPAFAAAAALLKREFTVPEVAQSLVITRVSGRASAMPESEKLKAFAATGAT
LAIHLAIHALDKVVAELTPVLGTDCPVAVVAKASWPDGRVVTGTLGDIAGQLEADPIPRTALILVGRALAAQDFRESALY
DTAYVRRFRGGGE
>Mature_252_residues
TVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSIVAPELLDYCPPGARIVDTAPLDLDRIEAEYVRAFAAGEDVARLHS
GDLSVYSAVAEQMRRLDRLSIPYTLTPGVPAFAAAAALLKREFTVPEVAQSLVITRVSGRASAMPESEKLKAFAATGATL
AIHLAIHALDKVVAELTPVLGTDCPVAVVAKASWPDGRVVTGTLGDIAGQLEADPIPRTALILVGRALAAQDFRESALYD
TAYVRRFRGGGE

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=241, Percent_Identity=24.896265560166, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26660; Mature: 26529

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSIVAPELLDYCPPGARIVDTAPLDLD
CEEEEEECCCCCCCEEEECCCHHHHHCCHHHHCCCHHHHHHHHHCCCCCEEEECCCCCHH
RIEAEYVRAFAAGEDVARLHSGDLSVYSAVAEQMRRLDRLSIPYTLTPGVPAFAAAAALL
HHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
KREFTVPEVAQSLVITRVSGRASAMPESEKLKAFAATGATLAIHLAIHALDKVVAELTPV
HHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LGTDCPVAVVAKASWPDGRVVTGTLGDIAGQLEADPIPRTALILVGRALAAQDFRESALY
HCCCCCEEEEEECCCCCCCEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DTAYVRRFRGGGE
HHHHHHHHCCCCC
>Mature Secondary Structure 
TVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSIVAPELLDYCPPGARIVDTAPLDLD
EEEEEECCCCCCCEEEECCCHHHHHCCHHHHCCCHHHHHHHHHCCCCCEEEECCCCCHH
RIEAEYVRAFAAGEDVARLHSGDLSVYSAVAEQMRRLDRLSIPYTLTPGVPAFAAAAALL
HHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
KREFTVPEVAQSLVITRVSGRASAMPESEKLKAFAATGATLAIHLAIHALDKVVAELTPV
HHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LGTDCPVAVVAKASWPDGRVVTGTLGDIAGQLEADPIPRTALILVGRALAAQDFRESALY
HCCCCCEEEEEECCCCCCCEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DTAYVRRFRGGGE
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]