Click here to switch to the map view.

The map label for this gene is ptxR [H]

Identifier: 154247175

GI number: 154247175

Start: 3602029

End: 3602934

Strand: Reverse

Name: ptxR [H]

Synonym: Xaut_3247

Alternate gene names: 154247175

Gene position: 3602934-3602029 (Counterclockwise)

Preceding gene: 154247177

Following gene: 154247173

Centisome position: 67.87

GC content: 71.3

Gene sequence:

>906_bases
ATGGATTGGGACCATCTGCGCGTTTTCCTCGCCGTGGCGCGGCAGGGGCAGCTTCTGGCGGCGGCGCGGCGACTGGGGCT
GAACCATGCCACGGTGGCCCGCCGGCTCGATGCGCTGGAAGAGGCCCTCGGCGCCCCATTGTTCGACCGCCGCCCCGCCG
GTTGCGTGCCCACCGAGGCCGGCGAGCGGCTGTTGCCGGCGGCCGAGCGGGTGGAAGCGGAGATGCTGGGCATCGCAGAA
GGTTTTCGCGACGCGGCGGCGGATGTCTCCGGCACGGTGCGCATCGGAGCGCCGGACGGCCTCGGCAACTACTTCCTCGC
CGCGGAGCTGGGCGCGCTCACCGCCCTCTATCCGGACCTGGTGGTGGAACTGGTGCCGCTGCCGCGCACCTTCTCCCTGT
CGCGGCGGGAGGCGGATCTCGCCATCGTGCTCGACCGCCCCATGGAAGGCCGGCTGCTGGTGTCGCGGCTCATCGACTAC
ACCCTCTCAGTCTATGCCGCCCGCGCCTATCTGGATCGCCACGGCACCCCCAAGAGCGTGGAAGACCTCGCCGGCCATGT
GGTGGTGACGGGAGTGGAGGACCTCGCCTATGCCTCGGCGCTGGATTATTCCGGCGTGCTGGAGAAGCACGGGCGCAGCC
GGTTCCGCTGCGCCAGCGTCATGGGCCAGATGGAGGCGGTGCGGGCGGGGGCCGGCATCGGCGTGCTGCACGATTTCGCC
GCCGGCCGGCATCTGGAGGCGCAGGGCCCGGATGCGCTGGTGCGGATCCTGCCCGGAATCGGCTTCCGCCGCTCCTATTT
CCTCCTCGCCCACCCCGACACGGCGCAGGTGCGGCGCATCGCGGTGCTGCGGGATGTGCTGGCGCAACGCTTCCGCGCCG
AGCGCGCCCGCTTCATCATCCCATGA

Upstream 100 bases:

>100_bases
GTCTGGGCCTCTTGAGCGGCAGGAAGGTGCCCCGTCTTCCCACTTCAAAAGATGCTCATCAATGCTATCATTTGAGCATC
TGTTATGCGGATTTTGAAGT

Downstream 100 bases:

>100_bases
AGATCGCGCGGTCGGCGCGGATGGTGGTGGTGATGGCCTCCAGCACCGCCCGCACCCGATTGAGGTGCTTGAGATCGTCA
TGCACCGACACCCAATAGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDWDHLRVFLAVARQGQLLAAARRLGLNHATVARRLDALEEALGAPLFDRRPAGCVPTEAGERLLPAAERVEAEMLGIAE
GFRDAAADVSGTVRIGAPDGLGNYFLAAELGALTALYPDLVVELVPLPRTFSLSRREADLAIVLDRPMEGRLLVSRLIDY
TLSVYAARAYLDRHGTPKSVEDLAGHVVVTGVEDLAYASALDYSGVLEKHGRSRFRCASVMGQMEAVRAGAGIGVLHDFA
AGRHLEAQGPDALVRILPGIGFRRSYFLLAHPDTAQVRRIAVLRDVLAQRFRAERARFIIP

Sequences:

>Translated_301_residues
MDWDHLRVFLAVARQGQLLAAARRLGLNHATVARRLDALEEALGAPLFDRRPAGCVPTEAGERLLPAAERVEAEMLGIAE
GFRDAAADVSGTVRIGAPDGLGNYFLAAELGALTALYPDLVVELVPLPRTFSLSRREADLAIVLDRPMEGRLLVSRLIDY
TLSVYAARAYLDRHGTPKSVEDLAGHVVVTGVEDLAYASALDYSGVLEKHGRSRFRCASVMGQMEAVRAGAGIGVLHDFA
AGRHLEAQGPDALVRILPGIGFRRSYFLLAHPDTAQVRRIAVLRDVLAQRFRAERARFIIP
>Mature_301_residues
MDWDHLRVFLAVARQGQLLAAARRLGLNHATVARRLDALEEALGAPLFDRRPAGCVPTEAGERLLPAAERVEAEMLGIAE
GFRDAAADVSGTVRIGAPDGLGNYFLAAELGALTALYPDLVVELVPLPRTFSLSRREADLAIVLDRPMEGRLLVSRLIDY
TLSVYAARAYLDRHGTPKSVEDLAGHVVVTGVEDLAYASALDYSGVLEKHGRSRFRCASVMGQMEAVRAGAGIGVLHDFA
AGRHLEAQGPDALVRILPGIGFRRSYFLLAHPDTAQVRRIAVLRDVLAQRFRAERARFIIP

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=256, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787128, Length=241, Percent_Identity=29.4605809128631, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=247, Percent_Identity=23.4817813765182, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081978, Length=182, Percent_Identity=29.1208791208791, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=26.4406779661017, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=166, Percent_Identity=25.3012048192771, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=184, Percent_Identity=28.2608695652174, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=30.4964539007092, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32719; Mature: 32719

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDHLRVFLAVARQGQLLAAARRLGLNHATVARRLDALEEALGAPLFDRRPAGCVPTEA
CCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GERLLPAAERVEAEMLGIAEGFRDAAADVSGTVRIGAPDGLGNYFLAAELGALTALYPDL
CCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VVELVPLPRTFSLSRREADLAIVLDRPMEGRLLVSRLIDYTLSVYAARAYLDRHGTPKSV
HHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EDLAGHVVVTGVEDLAYASALDYSGVLEKHGRSRFRCASVMGQMEAVRAGAGIGVLHDFA
HHHCCCEEEECHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGRHLEAQGPDALVRILPGIGFRRSYFLLAHPDTAQVRRIAVLRDVLAQRFRAERARFII
CCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
P
C
>Mature Secondary Structure
MDWDHLRVFLAVARQGQLLAAARRLGLNHATVARRLDALEEALGAPLFDRRPAGCVPTEA
CCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GERLLPAAERVEAEMLGIAEGFRDAAADVSGTVRIGAPDGLGNYFLAAELGALTALYPDL
CCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VVELVPLPRTFSLSRREADLAIVLDRPMEGRLLVSRLIDYTLSVYAARAYLDRHGTPKSV
HHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EDLAGHVVVTGVEDLAYASALDYSGVLEKHGRSRFRCASVMGQMEAVRAGAGIGVLHDFA
HHHCCCEEEECHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGRHLEAQGPDALVRILPGIGFRRSYFLLAHPDTAQVRRIAVLRDVLAQRFRAERARFII
CCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]