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The map label for this gene is rpiA [H]

Identifier: 154247149

GI number: 154247149

Start: 3568176

End: 3568937

Strand: Direct

Name: rpiA [H]

Synonym: Xaut_3221

Alternate gene names: 154247149

Gene position: 3568176-3568937 (Clockwise)

Preceding gene: 154247148

Following gene: 154247150

Centisome position: 67.21

GC content: 71.13

Gene sequence:

>762_bases
ATGCCCCACGCCGCGCCGGTTGGCCGCGCGAGGGGCACCGGAACGGAAACTCCCATGGTGCACGCCGAAGATCCGAAGCG
CCGCGCGGCCGCTCACGCCCTCACCTACGTGACCGACGGCATGCGCCTCGGCCTCGGCACCGGCTCCACCGCCCGCCATT
TCGTGGAGCTGTTGGCCGAGAAGGTCCATGCCGGCCTCAACATTCTCGGCGTGCCCACCTCAGAGCAGACTTTGTCGCAG
GCGGTCTCCCTCGGCGTTCCGATCGCGACGCTCGACGAGGCCGGTCCGCTCGACCTGTGCATCGACGGGGCGGACGAGGT
CGGCCCCGGCCTTGCCCTGATCAAGGGCGGCGGCGGAGCGCTACTGCGGGAGAAGATCGTCGCCAGCGCCGCGCGCGAGA
TGGTGGTGATCGCCGACTCGAGCAAGAAGGTGGCGATGCTCGGCCGCTTCCCGCTGCCCATCGAGGTGGTGGATTTCGGC
GTCGCCTCCATCGAGCGCCATGTGGCCGATGCGGTGCGCAAGGCCGGCTGCGAAGGCCCGGTGAAGCTGCGCCGCGACGG
CGATGGTCATCCTTTCGTCACCGATCAGGGCCACCTCATCCTCGACGTCCATCTCGGCCGCATCCCGGACCCGGCCGCGC
TCGCCCGCGCGGTGGAGGAAGTCGCCGGCGTGGTCGAGCACGGGCTGTTCCTCGGCCTCGCCCGCCGGGTCGTGCTCGCG
GGCGCGGACGGCATCACCGTGCTGGAGCCCGGCAGCTTCTGA

Upstream 100 bases:

>100_bases
CTTGGGGCCCATCGAGCCGTCGCGCCGCTTGTCGGCGGGCCGGATCGGGGCTAGAGCCGGAACGCGGCGGGGCGACCCGT
CCCGCAGCAACGAAACGCCA

Downstream 100 bases:

>100_bases
TTCCTCTTCCCGGAGAGAGACCCATGTTCATGTCCCATAGCGGCCGCTTCGGCGTGCGGCTCCTTCTCGCCGCCGCCTTT
GCGGTGCCGGCCCTTCCGGT

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPHAAPVGRARGTGTETPMVHAEDPKRRAAAHALTYVTDGMRLGLGTGSTARHFVELLAEKVHAGLNILGVPTSEQTLSQ
AVSLGVPIATLDEAGPLDLCIDGADEVGPGLALIKGGGGALLREKIVASAAREMVVIADSSKKVAMLGRFPLPIEVVDFG
VASIERHVADAVRKAGCEGPVKLRRDGDGHPFVTDQGHLILDVHLGRIPDPAALARAVEEVAGVVEHGLFLGLARRVVLA
GADGITVLEPGSF

Sequences:

>Translated_253_residues
MPHAAPVGRARGTGTETPMVHAEDPKRRAAAHALTYVTDGMRLGLGTGSTARHFVELLAEKVHAGLNILGVPTSEQTLSQ
AVSLGVPIATLDEAGPLDLCIDGADEVGPGLALIKGGGGALLREKIVASAAREMVVIADSSKKVAMLGRFPLPIEVVDFG
VASIERHVADAVRKAGCEGPVKLRRDGDGHPFVTDQGHLILDVHLGRIPDPAALARAVEEVAGVVEHGLFLGLARRVVLA
GADGITVLEPGSF
>Mature_252_residues
PHAAPVGRARGTGTETPMVHAEDPKRRAAAHALTYVTDGMRLGLGTGSTARHFVELLAEKVHAGLNILGVPTSEQTLSQA
VSLGVPIATLDEAGPLDLCIDGADEVGPGLALIKGGGGALLREKIVASAAREMVVIADSSKKVAMLGRFPLPIEVVDFGV
ASIERHVADAVRKAGCEGPVKLRRDGDGHPFVTDQGHLILDVHLGRIPDPAALARAVEEVAGVVEHGLFLGLARRVVLAG
ADGITVLEPGSF

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=243, Percent_Identity=37.8600823045267, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1789280, Length=232, Percent_Identity=38.3620689655172, Blast_Score=135, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17551758, Length=242, Percent_Identity=39.2561983471074, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324669, Length=237, Percent_Identity=32.4894514767932, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281364072, Length=218, Percent_Identity=34.8623853211009, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 26155; Mature: 26023

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHAAPVGRARGTGTETPMVHAEDPKRRAAAHALTYVTDGMRLGLGTGSTARHFVELLAE
CCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHH
KVHAGLNILGVPTSEQTLSQAVSLGVPIATLDEAGPLDLCIDGADEVGPGLALIKGGGGA
HHHCCCEEEECCCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCEEEEECCCCH
LLREKIVASAAREMVVIADSSKKVAMLGRFPLPIEVVDFGVASIERHVADAVRKAGCEGP
HHHHHHHHHHHHCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
VKLRRDGDGHPFVTDQGHLILDVHLGRIPDPAALARAVEEVAGVVEHGLFLGLARRVVLA
EEEEECCCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
GADGITVLEPGSF
CCCCEEEECCCCC
>Mature Secondary Structure 
PHAAPVGRARGTGTETPMVHAEDPKRRAAAHALTYVTDGMRLGLGTGSTARHFVELLAE
CCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHH
KVHAGLNILGVPTSEQTLSQAVSLGVPIATLDEAGPLDLCIDGADEVGPGLALIKGGGGA
HHHCCCEEEECCCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCEEEEECCCCH
LLREKIVASAAREMVVIADSSKKVAMLGRFPLPIEVVDFGVASIERHVADAVRKAGCEGP
HHHHHHHHHHHHCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
VKLRRDGDGHPFVTDQGHLILDVHLGRIPDPAALARAVEEVAGVVEHGLFLGLARRVVLA
EEEEECCCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
GADGITVLEPGSF
CCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA