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The map label for this gene is aspS

Identifier: 154247069

GI number: 154247069

Start: 3487005

End: 3488876

Strand: Direct

Name: aspS

Synonym: Xaut_3140

Alternate gene names: 154247069

Gene position: 3487005-3488876 (Clockwise)

Preceding gene: 154247066

Following gene: 154247070

Centisome position: 65.68

GC content: 67.15

Gene sequence:

>1872_bases
ATGCACCGTTACCGCTCCCATACTTGCGGCGCGCTTTCGACCGCCCAGGTGGGCGAGATCGTGCGCCTCTCCGGCTGGTG
CCACCGCATCCGCGACCACGGCGGCGTGCTCTTCATCGACCTGCGCGACCATTACGGCCTGACCCAGGTGGTGGTGGACC
CCGACAGCGCCGCCTTCAAGGATGCCGAGAAGGTGCGCGCCGAATGGGTGATCCGCATCGACGGCAAGGTGCGCCTGCGC
CCCGAGGGTACCGAGAACCCCGACCTCGCCACCGGCGCCGTGGAGGTCTACGCCACCGAGCTGGAAGTGCTGGGCCCCTC
GGCCGAGCTGCCGCTGCCCGTGTTCGGTGACGTGGAATATCCGGAAGAGACGCGCCTTCGCTACCGCTTCCTCGACCTGC
GGCGGGAGAAGCTCCACCGCAACATCATGACGCGGGGCGCGATCATCGATGCCATGCGCTCGCGCATGAAGGGGCAGGGC
TTCTTCGAATTCCAGACCCCCATCCTCACCGCCTCCTCGCCGGAGGGCGCGCGCGACTTCCTGGTGCCGAGCCGCCTGCA
CCCCGGCAAGTTCTATGCGCTGCCCCAGGCGCCGCAGCAGTACAAGCAGCTGATCATGATGAGCGGCTTCGACCGCTACT
TCCAGATCGCCCCCTGCTTCCGCGACGAGGACCCCCGCGCCGATCGCCTGCCCGGCGAGTTCTACCAGCTCGACCTGGAG
ATGAGCTTTGTCGAGCAGGAGGACATCTTCGCGGCGGTGGAGCCGGTCATCACCGGGGTGTTCGAGCAGTTCGCCGAAGG
CAAGCCGGTGACCCAGAAGTGGCCGCGCATCCCCTATGCGGAGTCCCTGCGCAAGTACGGCACCGACAAGCCGGACCTGC
GCAACCCGCTGGTGATGCAGAACGTGTCGGAGCATTTCCGCGGCTCGGGCTTCAAGGTGTTCGCCCGAATGCTGGAGGTG
GAGAAGAACGAGGTGTGGGCCATCCCCGCCCCCGGCGGCGGCTCTAGAGCCTTCTGCGACCGCATGAACAGCTGGGCCCA
GAGCGAAGGCCAGCCGGGGCTGGGCTACATCATGTGGCGGGATCTGTCTGCCGACGCTGCCGCTGGCGGCGAGAAGGCGG
TCAAGGATGCCCTTGAGAAGTCGCGCGGCCCGGGTGCCGGTGAGGGACATGTGGTCGAGCCTGGTGTTGTCGGCGCCGGC
CCGCTCGCCAACAACATCGGTCCCGAGCGCACCGAGGCGATCCGCGCCCAGCTCGACCTCAAGGCGGGCGATGCCGCCTT
CTTCGTCGCCGGCGACCCGGACAAGTTCGTGAAGTTCGCCGGCCTTGCCCGCACCCGCGTGGGCGAGGAGCTGAACCTCG
TCGACAAGGACCGCTTCGAGCTGGCCTGGATCGTCGACTTCCCCTTCTACGAATATTCGGAAGAAGAGAAGAAGGTCGAT
TTCTCGCACAATCCCTTCTCCATGCCCCAGGGCGGGCTGGACGCGCTGAACACGCAGGACCCGCTGTCGATCAAGGCGTT
CCAGTACGACATCGCCTGCAACGGCTACGAGATCGCGTCTGGCGGCATCCGCAACCATCGCCCCGAGGCCATGGTGAAGG
CGTTCGAGATCGCCGGCTATGACGCCCAGACGGTGGAGGAGCGCTTCGGCGGCATGTACCGTGCGTTCCAGTATGGCGCC
CCGCCCCATGGCGGCATGGCGGCGGGCGTGGACCGCATCGTGATGCTGCTGTGCGGCGTGACCAACCTGCGCGAAATCTC
GCTCTTCCCCATGAACCAGCAGGCCCTCGACCTGCTCATGGGCGCCCCGGCGGAGGCCGCCCCCAAGCAGCTGCGCGAGC
TTCACATTCGCCCGGCACCGCAGGCGAAATAG

Upstream 100 bases:

>100_bases
CCTCAGGCGTCCGGCGCGCGCCCATCTGGCTGCGCGCGGGGCGTCCGGACACCGGGCCCGCGGCCCGCGTCCTATCCCTT
CAGCCTTGAAAGGGCGACCC

Downstream 100 bases:

>100_bases
GTATAGCCTGTCCTGCGGGAACGCAGGACCGGGCGCACGCGACGCATCGGCGTTCCCGGGGAGGAACGCCGATGCGCACT
GTGTTTTCAAGGCTTGCTGT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MHRYRSHTCGALSTAQVGEIVRLSGWCHRIRDHGGVLFIDLRDHYGLTQVVVDPDSAAFKDAEKVRAEWVIRIDGKVRLR
PEGTENPDLATGAVEVYATELEVLGPSAELPLPVFGDVEYPEETRLRYRFLDLRREKLHRNIMTRGAIIDAMRSRMKGQG
FFEFQTPILTASSPEGARDFLVPSRLHPGKFYALPQAPQQYKQLIMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
MSFVEQEDIFAAVEPVITGVFEQFAEGKPVTQKWPRIPYAESLRKYGTDKPDLRNPLVMQNVSEHFRGSGFKVFARMLEV
EKNEVWAIPAPGGGSRAFCDRMNSWAQSEGQPGLGYIMWRDLSADAAAGGEKAVKDALEKSRGPGAGEGHVVEPGVVGAG
PLANNIGPERTEAIRAQLDLKAGDAAFFVAGDPDKFVKFAGLARTRVGEELNLVDKDRFELAWIVDFPFYEYSEEEKKVD
FSHNPFSMPQGGLDALNTQDPLSIKAFQYDIACNGYEIASGGIRNHRPEAMVKAFEIAGYDAQTVEERFGGMYRAFQYGA
PPHGGMAAGVDRIVMLLCGVTNLREISLFPMNQQALDLLMGAPAEAAPKQLRELHIRPAPQAK

Sequences:

>Translated_623_residues
MHRYRSHTCGALSTAQVGEIVRLSGWCHRIRDHGGVLFIDLRDHYGLTQVVVDPDSAAFKDAEKVRAEWVIRIDGKVRLR
PEGTENPDLATGAVEVYATELEVLGPSAELPLPVFGDVEYPEETRLRYRFLDLRREKLHRNIMTRGAIIDAMRSRMKGQG
FFEFQTPILTASSPEGARDFLVPSRLHPGKFYALPQAPQQYKQLIMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
MSFVEQEDIFAAVEPVITGVFEQFAEGKPVTQKWPRIPYAESLRKYGTDKPDLRNPLVMQNVSEHFRGSGFKVFARMLEV
EKNEVWAIPAPGGGSRAFCDRMNSWAQSEGQPGLGYIMWRDLSADAAAGGEKAVKDALEKSRGPGAGEGHVVEPGVVGAG
PLANNIGPERTEAIRAQLDLKAGDAAFFVAGDPDKFVKFAGLARTRVGEELNLVDKDRFELAWIVDFPFYEYSEEEKKVD
FSHNPFSMPQGGLDALNTQDPLSIKAFQYDIACNGYEIASGGIRNHRPEAMVKAFEIAGYDAQTVEERFGGMYRAFQYGA
PPHGGMAAGVDRIVMLLCGVTNLREISLFPMNQQALDLLMGAPAEAAPKQLRELHIRPAPQAK
>Mature_623_residues
MHRYRSHTCGALSTAQVGEIVRLSGWCHRIRDHGGVLFIDLRDHYGLTQVVVDPDSAAFKDAEKVRAEWVIRIDGKVRLR
PEGTENPDLATGAVEVYATELEVLGPSAELPLPVFGDVEYPEETRLRYRFLDLRREKLHRNIMTRGAIIDAMRSRMKGQG
FFEFQTPILTASSPEGARDFLVPSRLHPGKFYALPQAPQQYKQLIMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
MSFVEQEDIFAAVEPVITGVFEQFAEGKPVTQKWPRIPYAESLRKYGTDKPDLRNPLVMQNVSEHFRGSGFKVFARMLEV
EKNEVWAIPAPGGGSRAFCDRMNSWAQSEGQPGLGYIMWRDLSADAAAGGEKAVKDALEKSRGPGAGEGHVVEPGVVGAG
PLANNIGPERTEAIRAQLDLKAGDAAFFVAGDPDKFVKFAGLARTRVGEELNLVDKDRFELAWIVDFPFYEYSEEEKKVD
FSHNPFSMPQGGLDALNTQDPLSIKAFQYDIACNGYEIASGGIRNHRPEAMVKAFEIAGYDAQTVEERFGGMYRAFQYGA
PPHGGMAAGVDRIVMLLCGVTNLREISLFPMNQQALDLLMGAPAEAAPKQLRELHIRPAPQAK

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=630, Percent_Identity=32.8571428571429, Blast_Score=323, Evalue=4e-88,
Organism=Homo sapiens, GI45439306, Length=325, Percent_Identity=25.8461538461538, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226491502, Length=246, Percent_Identity=26.4227642276423, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4758762, Length=248, Percent_Identity=22.9838709677419, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788173, Length=623, Percent_Identity=38.2022471910112, Blast_Score=413, Evalue=1e-116,
Organism=Escherichia coli, GI1790571, Length=219, Percent_Identity=28.7671232876712, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789256, Length=219, Percent_Identity=28.7671232876712, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32566633, Length=351, Percent_Identity=35.042735042735, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=296, Percent_Identity=23.6486486486486, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551876, Length=278, Percent_Identity=27.3381294964029, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=334, Percent_Identity=34.1317365269461, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6321807, Length=282, Percent_Identity=26.9503546099291, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=266, Percent_Identity=24.812030075188, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584738, Length=627, Percent_Identity=31.7384370015949, Blast_Score=280, Evalue=3e-75,
Organism=Drosophila melanogaster, GI17136276, Length=315, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19921528, Length=236, Percent_Identity=25.8474576271186, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640849, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640851, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_XANP2 (A7IK27)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001418027.1
- ProteinModelPortal:   A7IK27
- SMR:   A7IK27
- STRING:   A7IK27
- GeneID:   5421354
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3140
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   YQLDVEM
- ProtClustDB:   PRK00476
- BioCyc:   XAUT78245:XAUT_3140-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 69424; Mature: 69424

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRYRSHTCGALSTAQVGEIVRLSGWCHRIRDHGGVLFIDLRDHYGLTQVVVDPDSAAFK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCHHHH
DAEKVRAEWVIRIDGKVRLRPEGTENPDLATGAVEVYATELEVLGPSAELPLPVFGDVEY
HHHHHCEEEEEEECCEEEECCCCCCCCCCCCCEEEEEEEEHEEECCCCCCCCCCCCCCCC
PEETRLRYRFLDLRREKLHRNIMTRGAIIDAMRSRMKGQGFFEFQTPILTASSPEGARDF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHC
LVPSRLHPGKFYALPQAPQQYKQLIMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
CCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEE
MSFVEQEDIFAAVEPVITGVFEQFAEGKPVTQKWPRIPYAESLRKYGTDKPDLRNPLVMQ
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
NVSEHFRGSGFKVFARMLEVEKNEVWAIPAPGGGSRAFCDRMNSWAQSEGQPGLGYIMWR
HHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
DLSADAAAGGEKAVKDALEKSRGPGAGEGHVVEPGVVGAGPLANNIGPERTEAIRAQLDL
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHEEE
KAGDAAFFVAGDPDKFVKFAGLARTRVGEELNLVDKDRFELAWIVDFPFYEYSEEEKKVD
ECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCC
FSHNPFSMPQGGLDALNTQDPLSIKAFQYDIACNGYEIASGGIRNHRPEAMVKAFEIAGY
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEECCCCCCCCCHHHHHHHHHHCCC
DAQTVEERFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGVTNLREISLFPMNQQALDLLM
CHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
GAPAEAAPKQLRELHIRPAPQAK
CCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHRYRSHTCGALSTAQVGEIVRLSGWCHRIRDHGGVLFIDLRDHYGLTQVVVDPDSAAFK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCHHHH
DAEKVRAEWVIRIDGKVRLRPEGTENPDLATGAVEVYATELEVLGPSAELPLPVFGDVEY
HHHHHCEEEEEEECCEEEECCCCCCCCCCCCCEEEEEEEEHEEECCCCCCCCCCCCCCCC
PEETRLRYRFLDLRREKLHRNIMTRGAIIDAMRSRMKGQGFFEFQTPILTASSPEGARDF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHC
LVPSRLHPGKFYALPQAPQQYKQLIMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
CCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEE
MSFVEQEDIFAAVEPVITGVFEQFAEGKPVTQKWPRIPYAESLRKYGTDKPDLRNPLVMQ
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
NVSEHFRGSGFKVFARMLEVEKNEVWAIPAPGGGSRAFCDRMNSWAQSEGQPGLGYIMWR
HHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
DLSADAAAGGEKAVKDALEKSRGPGAGEGHVVEPGVVGAGPLANNIGPERTEAIRAQLDL
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHEEE
KAGDAAFFVAGDPDKFVKFAGLARTRVGEELNLVDKDRFELAWIVDFPFYEYSEEEKKVD
ECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCHHCCCC
FSHNPFSMPQGGLDALNTQDPLSIKAFQYDIACNGYEIASGGIRNHRPEAMVKAFEIAGY
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEECCCCCCCCCHHHHHHHHHHCCC
DAQTVEERFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGVTNLREISLFPMNQQALDLLM
CHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
GAPAEAAPKQLRELHIRPAPQAK
CCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA