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The map label for this gene is aroB [H]

Identifier: 154247055

GI number: 154247055

Start: 3466285

End: 3467796

Strand: Reverse

Name: aroB [H]

Synonym: Xaut_3126

Alternate gene names: 154247055

Gene position: 3467796-3466285 (Counterclockwise)

Preceding gene: 154247056

Following gene: 154247054

Centisome position: 65.32

GC content: 71.03

Gene sequence:

>1512_bases
GTGACCCGCGCGCCCGGCCGGCTCTTCACCGGGGCGCCGGTCGCGGTCATAGATATCGGCTCCAACTCGGTCCGCCTCGT
GGTCTATGAGGGGCTGAGCCGCGCGCTCACGCCCATCTTCAACGAGAAGGCCCTGTGCGGGCTCGGCCGCGAGGTGCTCT
CCACCGGGCGCCTGCCGCAGGATGCGGTGGACCGTGCCCTGGCCGCGCTGAAGCGGTTCCGCGCCCTGTGCGACGCAATG
GAGGTGGGCGAGGTCCATGCCCTCGCCACCGCCGCCGCGCGCGACGCGGAAAACGGCCCGGCCTTCATCGCCGAATGCGA
GGCCATCTGCGGCCGCAAGATCGAGCTGCTCACCGGCAAGCGCGAGGCGGAGCTCGCCGCCGCCGGCGTGGTGGCCGGCG
TCCATGCGCCGGACGGCATCGTGGGCGATCTCGGCGGCGGCTCGCTGGAGCTGGTGGACGTGAAGGGCCGCGCCATCGGC
ACCGGCGTCACCCTGCCGCTCGGCGGGCTCGCCCTGCAGGACCGCTCGTCCCGCTCGCCGCGCAAGGCGGAAAAGATCGT
CCGCGAGACCATCCCCGAGGCCGAGGTTCTGGGCGCCCTTGCTGGCCGCACCTTCTATGCGGTGGGCGGAACGTGGCGGG
CGCTGGCGCGCCTCCACATGTACACCAAGGGCTATCCGCTTCACGTGATGCACGGCTATGTGATTCCCGCCCGCGAGGCG
CTGGACTTCACCCGCATCGTGCACCGCGCCGACGCCGAGGCCCTCGCCCATATCGACGTGGTCTCCGACGCCCGCCGTCC
TCTGCTCGCCTACGGCGCGCTGGTGCTGGAGAACATCGTGCGGCAGGGCCGTCCGTCGGAGGTGGTCATCTCCGCCCTCG
GCGTGCGCGAGGGCCTGCTGCATTCCCTGATGCCTGAAGAGGAGCGCGTCCGCGACCCGCTCCTGATCGCGGCAGCCGAG
ATGAACGTGCTGCGCTCCCGCTCGCCCCGCCACGGGGAGGAGCTGGTGGCCTGGACCGATGGCTTCTTCGCCTCGGCGCC
GGTGCTGGAGGAAGCAGAGGACGAGAAGCGCCTGCGCCGCGCCGCCTGCCTGCTGGCAGACGTGAGCTGGCGCGCGCACC
CGGACTATCGCGGCGAGCAGAGCCTGAACATGATCGCCCATGCGGCGTTCGCCGGCATCGATCATCCCGGCCGGGCCTAT
ATCGCCCTCTCGGTCTATTTCCGGCACATGGGCCTCAACACCGACGAATCCGACACCCGCATCCTGGAATTGCTGACCAC
CGGCATGCTCGACCGCGCGCGCATCCTCGGCGCCGTGATGCGGGTCGCCTACGTGCTGTCGGCGGCCATGCCCGGCATCC
TGCCGCAGATGCCGCTGCAGGTGCGCGGCGACCAGCTGGTGCTGAGCGTGCCGCGCAAGGTGGTCTCGCTGGTGAACGAC
CGGGTCTATAATCGCCTGCGCCAGCTGGCCCGGCTCATCGGCCGCGAGCCATTGCTCGAACAGGGCGACTGA

Upstream 100 bases:

>100_bases
CATCAATATTTCATGACCAACCCGAGCTTGTCCGGACGTGGAAAGTCTCTCAAAGATTCTTCGCCGCGTAGCCTCTTCGT
CCGTCGCTGACGGCGAGGAG

Downstream 100 bases:

>100_bases
CCGGCCCGGACGGGGTCTGCCAGCCTTCCCCTCGCCTCGGGCGGGCGCTGATACACCTGTGACCGGCGTCACGCCGACGG
CGCGGGGCGGTCGCAAGTCC

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTRAPGRLFTGAPVAVIDIGSNSVRLVVYEGLSRALTPIFNEKALCGLGREVLSTGRLPQDAVDRALAALKRFRALCDAM
EVGEVHALATAAARDAENGPAFIAECEAICGRKIELLTGKREAELAAAGVVAGVHAPDGIVGDLGGGSLELVDVKGRAIG
TGVTLPLGGLALQDRSSRSPRKAEKIVRETIPEAEVLGALAGRTFYAVGGTWRALARLHMYTKGYPLHVMHGYVIPAREA
LDFTRIVHRADAEALAHIDVVSDARRPLLAYGALVLENIVRQGRPSEVVISALGVREGLLHSLMPEEERVRDPLLIAAAE
MNVLRSRSPRHGEELVAWTDGFFASAPVLEEAEDEKRLRRAACLLADVSWRAHPDYRGEQSLNMIAHAAFAGIDHPGRAY
IALSVYFRHMGLNTDESDTRILELLTTGMLDRARILGAVMRVAYVLSAAMPGILPQMPLQVRGDQLVLSVPRKVVSLVND
RVYNRLRQLARLIGREPLLEQGD

Sequences:

>Translated_503_residues
MTRAPGRLFTGAPVAVIDIGSNSVRLVVYEGLSRALTPIFNEKALCGLGREVLSTGRLPQDAVDRALAALKRFRALCDAM
EVGEVHALATAAARDAENGPAFIAECEAICGRKIELLTGKREAELAAAGVVAGVHAPDGIVGDLGGGSLELVDVKGRAIG
TGVTLPLGGLALQDRSSRSPRKAEKIVRETIPEAEVLGALAGRTFYAVGGTWRALARLHMYTKGYPLHVMHGYVIPAREA
LDFTRIVHRADAEALAHIDVVSDARRPLLAYGALVLENIVRQGRPSEVVISALGVREGLLHSLMPEEERVRDPLLIAAAE
MNVLRSRSPRHGEELVAWTDGFFASAPVLEEAEDEKRLRRAACLLADVSWRAHPDYRGEQSLNMIAHAAFAGIDHPGRAY
IALSVYFRHMGLNTDESDTRILELLTTGMLDRARILGAVMRVAYVLSAAMPGILPQMPLQVRGDQLVLSVPRKVVSLVND
RVYNRLRQLARLIGREPLLEQGD
>Mature_502_residues
TRAPGRLFTGAPVAVIDIGSNSVRLVVYEGLSRALTPIFNEKALCGLGREVLSTGRLPQDAVDRALAALKRFRALCDAME
VGEVHALATAAARDAENGPAFIAECEAICGRKIELLTGKREAELAAAGVVAGVHAPDGIVGDLGGGSLELVDVKGRAIGT
GVTLPLGGLALQDRSSRSPRKAEKIVRETIPEAEVLGALAGRTFYAVGGTWRALARLHMYTKGYPLHVMHGYVIPAREAL
DFTRIVHRADAEALAHIDVVSDARRPLLAYGALVLENIVRQGRPSEVVISALGVREGLLHSLMPEEERVRDPLLIAAAEM
NVLRSRSPRHGEELVAWTDGFFASAPVLEEAEDEKRLRRAACLLADVSWRAHPDYRGEQSLNMIAHAAFAGIDHPGRAYI
ALSVYFRHMGLNTDESDTRILELLTTGMLDRARILGAVMRVAYVLSAAMPGILPQMPLQVRGDQLVLSVPRKVVSLVNDR
VYNRLRQLARLIGREPLLEQGD

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=220, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321185, Length=494, Percent_Identity=27.7327935222672, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 54443; Mature: 54312

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAPGRLFTGAPVAVIDIGSNSVRLVVYEGLSRALTPIFNEKALCGLGREVLSTGRLPQ
CCCCCCCEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHCCHHHHHCCHHHHHCCCCCH
DAVDRALAALKRFRALCDAMEVGEVHALATAAARDAENGPAFIAECEAICGRKIELLTGK
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCC
REAELAAAGVVAGVHAPDGIVGDLGGGSLELVDVKGRAIGTGVTLPLGGLALQDRSSRSP
CHHHHHHHHHHEECCCCCCCEECCCCCEEEEEEECCCEECCCCCCCCCCEEECCCCCCCH
RKAEKIVRETIPEAEVLGALAGRTFYAVGGTWRALARLHMYTKGYPLHVMHGYVIPAREA
HHHHHHHHHHCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCEEEEECEEECHHHH
LDFTRIVHRADAEALAHIDVVSDARRPLLAYGALVLENIVRQGRPSEVVISALGVREGLL
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
HSLMPEEERVRDPLLIAAAEMNVLRSRSPRHGEELVAWTDGFFASAPVLEEAEDEKRLRR
HHHCCCHHHCCCCEEEEHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
AACLLADVSWRAHPDYRGEQSLNMIAHAAFAGIDHPGRAYIALSVYFRHMGLNTDESDTR
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCHHHH
ILELLTTGMLDRARILGAVMRVAYVLSAAMPGILPQMPLQVRGDQLVLSVPRKVVSLVND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEHHHHHHHHHHHHH
RVYNRLRQLARLIGREPLLEQGD
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRAPGRLFTGAPVAVIDIGSNSVRLVVYEGLSRALTPIFNEKALCGLGREVLSTGRLPQ
CCCCCCEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHCCHHHHHCCHHHHHCCCCCH
DAVDRALAALKRFRALCDAMEVGEVHALATAAARDAENGPAFIAECEAICGRKIELLTGK
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCC
REAELAAAGVVAGVHAPDGIVGDLGGGSLELVDVKGRAIGTGVTLPLGGLALQDRSSRSP
CHHHHHHHHHHEECCCCCCCEECCCCCEEEEEEECCCEECCCCCCCCCCEEECCCCCCCH
RKAEKIVRETIPEAEVLGALAGRTFYAVGGTWRALARLHMYTKGYPLHVMHGYVIPAREA
HHHHHHHHHHCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCEEEEECEEECHHHH
LDFTRIVHRADAEALAHIDVVSDARRPLLAYGALVLENIVRQGRPSEVVISALGVREGLL
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
HSLMPEEERVRDPLLIAAAEMNVLRSRSPRHGEELVAWTDGFFASAPVLEEAEDEKRLRR
HHHCCCHHHCCCCEEEEHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
AACLLADVSWRAHPDYRGEQSLNMIAHAAFAGIDHPGRAYIALSVYFRHMGLNTDESDTR
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCHHHH
ILELLTTGMLDRARILGAVMRVAYVLSAAMPGILPQMPLQVRGDQLVLSVPRKVVSLVND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEHHHHHHHHHHHHH
RVYNRLRQLARLIGREPLLEQGD
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]