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The map label for this gene is surA [C]

Identifier: 154247041

GI number: 154247041

Start: 3451404

End: 3452420

Strand: Direct

Name: surA [C]

Synonym: Xaut_3112

Alternate gene names: 154247041

Gene position: 3451404-3452420 (Clockwise)

Preceding gene: 154247038

Following gene: 154247046

Centisome position: 65.01

GC content: 68.04

Gene sequence:

>1017_bases
ATGCCCTCTTGTCAGCTGAGGAGAGCTAAGCGAGGTTGCGCCCCGCTTCGGCCCGCCCGAAGACATCCCGAGGAAACCGG
ACCCATGATGCGTTCCGCCAAAACCCGTCTTTTCGCCGCCGCGCTCGCCGCGACCGTCTCCGTCGCGTCCGTCTCGGCGG
CGCTCGCGCAGGGGGCCGCCCCGGCCGCTCCCCCCGCCGCGACGCAGGCGGCGCCGGCCCCTGACACCGTGGTCGCGACC
GTCAACGGGACGCCCATCCGCCAGAGCGACGTGACCATCGCCCTCGAGGACATCGGCGCCGGCCTGCCGCCCCAGCTCCA
GGGCGCGCAGCGGGAGGAATATGTCCTGTCCTTCCTCACCGACATGACCCTGCTGGCCAAGGCCGCCGAGGCGCAGAAGC
TCGACCAGTCGCCGGATTTCCAGCAGCGCATCGCCTATGCCCGCACCAAGGCGCTCATGGAAACGCTGATGACCCAGGAA
GCCAAGAAGGCGGTTTCCGAAGAGGCCAAGCACAAGACTTATGACGAGTTCGTCAAGTCCGCGCCCGCCGAGGCGGAGGT
CCGCGCCCGCCACATCCTGGTGGACGACGAGGCCAAGGCCAAGGAAATCGCCAAGAAGGCCAAGGCCGGCGAGGATTTCG
CCAAGCTCGCCAAGGACTATTCCAAGGACAGCGCCGAGGACGGCGGGGATCTCGGCTATTTCACCAAGGACCAGATGGTG
CCCGAGTTCGCCGAGGCCGCCTTCAAGCTGGACAAGGGCCAGGTCTCCGACCCGGTGAAGAGCCAGTTCGGCTGGCATGT
CATCAAGGTCGAGGACAAGCGCCAGAAGCCGGTTCCCACCTATGATCAGGTGTCGGACCAGGTGGAGCAGTACCTCGTGC
GCAAGGCCCAGGCGGACCTCGTCACCAAGCTGCGCACCGATGCCAAGATCGAGAAGGCCGCGGCTGCGGCGCCTGCTCCG
GCGGCGCCTGCTGCTCCCGCCGCGCCGGCTCCCGCGGCCGACCCCGCCAAGAAGTGA

Upstream 100 bases:

>100_bases
GAACGGCCAGCATTCCCGATGGAAGGCGCGCCTTATACAGGCTCGCGCGAGGGAACGAAAGCCCCGCAGCGCGCTTTTCC
AGTCGCTCTATGCCCCAACA

Downstream 100 bases:

>100_bases
TCGCGGTTACACGCCGGTCCTGAAGGGGCGCTTCGGCGCCCCTTTTCATGTCCGCTCGGGTCTCGTGCACGTGTCCGGGG
CGCCGGTCAAAGCTCCTCCA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPSCQLRRAKRGCAPLRPARRHPEETGPMMRSAKTRLFAAALAATVSVASVSAALAQGAAPAAPPAATQAAPAPDTVVAT
VNGTPIRQSDVTIALEDIGAGLPPQLQGAQREEYVLSFLTDMTLLAKAAEAQKLDQSPDFQQRIAYARTKALMETLMTQE
AKKAVSEEAKHKTYDEFVKSAPAEAEVRARHILVDDEAKAKEIAKKAKAGEDFAKLAKDYSKDSAEDGGDLGYFTKDQMV
PEFAEAAFKLDKGQVSDPVKSQFGWHVIKVEDKRQKPVPTYDQVSDQVEQYLVRKAQADLVTKLRTDAKIEKAAAAAPAP
AAPAAPAAPAPAADPAKK

Sequences:

>Translated_338_residues
MPSCQLRRAKRGCAPLRPARRHPEETGPMMRSAKTRLFAAALAATVSVASVSAALAQGAAPAAPPAATQAAPAPDTVVAT
VNGTPIRQSDVTIALEDIGAGLPPQLQGAQREEYVLSFLTDMTLLAKAAEAQKLDQSPDFQQRIAYARTKALMETLMTQE
AKKAVSEEAKHKTYDEFVKSAPAEAEVRARHILVDDEAKAKEIAKKAKAGEDFAKLAKDYSKDSAEDGGDLGYFTKDQMV
PEFAEAAFKLDKGQVSDPVKSQFGWHVIKVEDKRQKPVPTYDQVSDQVEQYLVRKAQADLVTKLRTDAKIEKAAAAAPAP
AAPAAPAAPAPAADPAKK
>Mature_337_residues
PSCQLRRAKRGCAPLRPARRHPEETGPMMRSAKTRLFAAALAATVSVASVSAALAQGAAPAAPPAATQAAPAPDTVVATV
NGTPIRQSDVTIALEDIGAGLPPQLQGAQREEYVLSFLTDMTLLAKAAEAQKLDQSPDFQQRIAYARTKALMETLMTQEA
KKAVSEEAKHKTYDEFVKSAPAEAEVRARHILVDDEAKAKEIAKKAKAGEDFAKLAKDYSKDSAEDGGDLGYFTKDQMVP
EFAEAAFKLDKGQVSDPVKSQFGWHVIKVEDKRQKPVPTYDQVSDQVEQYLVRKAQADLVTKLRTDAKIEKAAAAAPAPA
APAAPAAPAPAADPAKK

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=94, Percent_Identity=44.6808510638298, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786238, Length=102, Percent_Identity=46.078431372549, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790211, Length=83, Percent_Identity=44.578313253012, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17537235, Length=94, Percent_Identity=46.8085106382979, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356303, Length=94, Percent_Identity=42.5531914893617, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 36081; Mature: 35950

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSCQLRRAKRGCAPLRPARRHPEETGPMMRSAKTRLFAAALAATVSVASVSAALAQGAA
CCCHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAAPPAATQAAPAPDTVVATVNGTPIRQSDVTIALEDIGAGLPPQLQGAQREEYVLSFLT
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHCCCCCHHCCCCHHHHHHHHHHH
DMTLLAKAAEAQKLDQSPDFQQRIAYARTKALMETLMTQEAKKAVSEEAKHKTYDEFVKS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAEAEVRARHILVDDEAKAKEIAKKAKAGEDFAKLAKDYSKDSAEDGGDLGYFTKDQMV
CCCCHHHHHHHEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
PEFAEAAFKLDKGQVSDPVKSQFGWHVIKVEDKRQKPVPTYDQVSDQVEQYLVRKAQADL
HHHHHHHHHCCCCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VTKLRTDAKIEKAAAAAPAPAAPAAPAAPAPAADPAKK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSCQLRRAKRGCAPLRPARRHPEETGPMMRSAKTRLFAAALAATVSVASVSAALAQGAA
CCHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAAPPAATQAAPAPDTVVATVNGTPIRQSDVTIALEDIGAGLPPQLQGAQREEYVLSFLT
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHCCCCCHHCCCCHHHHHHHHHHH
DMTLLAKAAEAQKLDQSPDFQQRIAYARTKALMETLMTQEAKKAVSEEAKHKTYDEFVKS
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAEAEVRARHILVDDEAKAKEIAKKAKAGEDFAKLAKDYSKDSAEDGGDLGYFTKDQMV
CCCCHHHHHHHEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
PEFAEAAFKLDKGQVSDPVKSQFGWHVIKVEDKRQKPVPTYDQVSDQVEQYLVRKAQADL
HHHHHHHHHCCCCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VTKLRTDAKIEKAAAAAPAPAAPAAPAAPAPAADPAKK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]