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The map label for this gene is yciL [C]

Identifier: 154247023

GI number: 154247023

Start: 3435003

End: 3436865

Strand: Reverse

Name: yciL [C]

Synonym: Xaut_3094

Alternate gene names: 154247023

Gene position: 3436865-3435003 (Counterclockwise)

Preceding gene: 154247025

Following gene: 154247022

Centisome position: 64.74

GC content: 73.38

Gene sequence:

>1863_bases
ATGCCGCGCACATCACCGCCCCGCAAGGACAAGAACCGCGTTCCGCGCATCAAGCGCGAACTCACCCCCGCCGCGCCCAA
GGAGGCCGAGCGGATCGCCAAGGTCGTCGCCCGCGCCGGCCTCGGCTCGCGCCGCGAGATCGAGGAATGGATCGAGGCCG
GCCGCGTGGCCGTCAACGGCGAGGTGCTCACCACCCCTGCCGTCACCGTCACGGCCGAGGATGCCATCACCGTCGATGGC
GCCCCCCTGCCCGAGCGCGAACGCACCCGCCTCTTCATTTACCACAAGCCCAGGGGCGTGGTGACCACCAATCGCGACCC
TGAAGGCCGCACCACCCTGTTCGAGATCCTGCCCCAGGGCCTGCCGCGCCTCGTGAGCGTCGGGCGGCTGGATCTGAATT
CGGAAGGCCTGCTGCTGCTCACCAACGACGGCGGACTTGCCCGCGTGCTGGAGCTGCCGGAGACCGGCTGGCTGCGCCGC
TACCGCGTGCGCGCCAATGGCGAGGTCAACCAGGCCCAGCTCGACAGCCTGCTGAAGGGCATCACCGTCGATGGGGTGGA
GTACGGCCCCATCGAGGCGGAGCTGGACCGGGTGCAGGGCGCCAATGCCTGGATCACGGTGTCCCTGCGCGAGGGCAAGA
ACCGGGAAATCCGCAATGTGTTCGGCGCCTTGGGCCTCCAGGTGAACCGGCTGATCCGCGTCTCCTACGGCCCGTTCCAG
CTGGGCGATGTCCCGGAAGGTGGCATCGAGGAGGTGCGCACCCGCGTGCTGCGCGACCAGATCGGCAACGACCTCGCCGC
CGCCGCAGGAGCCGATTTCACCGGCCTGCTGGTGGAGCGCGAGCTGGAAGAGGCCCCGCCCCGCGTGGCACTGCGCCCCG
CCGGCAAGCGTCAGGCTGCAGCCGAGAAGGGCGGCACCCTGAAGGCGCCGGCCCGCCGTTCGCGGCAGGACGAGGATTTC
GACGCGCCGGTGGAGGATGTCATCCGCCCCGCCGGCCCCCGCACGCGCCGGCGCATGAGCGATGAAAATGCCGTGGAGAG
CCGTGGCTCGGTGGCCGACCGCAAGGGCCGCACGGTGAAGGTGGAACGCGTGGTGGCGCCCAAGGCAGACGCCCCGACGC
GTGGCGCCCGAACTGGTGCCCGGCCCGGTGCCCGCAAGAGCGACAGGGACGAAGCAGGAGCCCGCCCGTTCCGCCGCGGT
CCGGCCGAGGGCAAGGAGCGCTTTTCCGAGCGCGGACCAGCCCGCGCCGGTTTCCGCGACGATGCCCGTGGCCCGCGCCG
CGAGCGCGATGATCGCGAGGATTTCCGTCGCCGTCCCACCCGGGAGGGAGAGGATCGCCCCCGTCGCCCGCGTCCGGAGA
CAGCGGATGGCGCCCCCCGGCGCGGCCGCGACGAGCGCCCGCAGCAGGGCGAGCGGCCCTTCCGCACCCGCAGCGAACGG
CCGGACCGCACCAGCGAGCAGGAGGGCCGGCCCGCCCGTGGCGGCAGCCGTCCTTATGGCGACAAGCCGGCGGGGCGTGC
CCGTCCGACGGGTGACCGGCCGGCGGGTGCTGGCCGCGCTTACGGCGAGAAATCCGAAGGCTCGGGTCGCGCTTATGGCG
ACAAGCCGGCGCGGAGCCGCCCCTCCGGTGACAGGCCCACGGGCGGCGCTGGTCGCTCCTACAGCGAACGCTCGTCCGAA
GGTGCGGGTCGCGCTTTCGGCGACAAGCCGGCCGGCGCGCGCAGTTTCGGCGGCAAGCCGGGGGGCAAGCCCGGCGCCGG
TCGTGGCGGCTTCGGTGGCAAGCCCGGCGGAAAGCCCGGCGGGCGCGCGGGCGGTGGCAAGGCTGGCGGCGGCAAGCCTG
CGGGTCCGCGCGGCAAGCGCTGA

Upstream 100 bases:

>100_bases
CCCGCGCCTCGTTCAGCGCCATCTGCATATAGGTTCCGGACATGGTGCCTCTGTCATCGCCGCGCTCGCCGCGCCGCCTC
GCCTGTGCTAACTGCCCCTC

Downstream 100 bases:

>100_bases
TCGGCGAGAAAATCGTCCATGCGCATCGTCGGCGGCAGATTGAAAGGGCGCGCGCTGAAGGGCCCTTCCTCCAGCGCCAC
CCGGCCCACCTCGGACCGGC

Product: RNA-binding S4 domain-containing protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MPRTSPPRKDKNRVPRIKRELTPAAPKEAERIAKVVARAGLGSRREIEEWIEAGRVAVNGEVLTTPAVTVTAEDAITVDG
APLPERERTRLFIYHKPRGVVTTNRDPEGRTTLFEILPQGLPRLVSVGRLDLNSEGLLLLTNDGGLARVLELPETGWLRR
YRVRANGEVNQAQLDSLLKGITVDGVEYGPIEAELDRVQGANAWITVSLREGKNREIRNVFGALGLQVNRLIRVSYGPFQ
LGDVPEGGIEEVRTRVLRDQIGNDLAAAAGADFTGLLVERELEEAPPRVALRPAGKRQAAAEKGGTLKAPARRSRQDEDF
DAPVEDVIRPAGPRTRRRMSDENAVESRGSVADRKGRTVKVERVVAPKADAPTRGARTGARPGARKSDRDEAGARPFRRG
PAEGKERFSERGPARAGFRDDARGPRRERDDREDFRRRPTREGEDRPRRPRPETADGAPRRGRDERPQQGERPFRTRSER
PDRTSEQEGRPARGGSRPYGDKPAGRARPTGDRPAGAGRAYGEKSEGSGRAYGDKPARSRPSGDRPTGGAGRSYSERSSE
GAGRAFGDKPAGARSFGGKPGGKPGAGRGGFGGKPGGKPGGRAGGGKAGGGKPAGPRGKR

Sequences:

>Translated_620_residues
MPRTSPPRKDKNRVPRIKRELTPAAPKEAERIAKVVARAGLGSRREIEEWIEAGRVAVNGEVLTTPAVTVTAEDAITVDG
APLPERERTRLFIYHKPRGVVTTNRDPEGRTTLFEILPQGLPRLVSVGRLDLNSEGLLLLTNDGGLARVLELPETGWLRR
YRVRANGEVNQAQLDSLLKGITVDGVEYGPIEAELDRVQGANAWITVSLREGKNREIRNVFGALGLQVNRLIRVSYGPFQ
LGDVPEGGIEEVRTRVLRDQIGNDLAAAAGADFTGLLVERELEEAPPRVALRPAGKRQAAAEKGGTLKAPARRSRQDEDF
DAPVEDVIRPAGPRTRRRMSDENAVESRGSVADRKGRTVKVERVVAPKADAPTRGARTGARPGARKSDRDEAGARPFRRG
PAEGKERFSERGPARAGFRDDARGPRRERDDREDFRRRPTREGEDRPRRPRPETADGAPRRGRDERPQQGERPFRTRSER
PDRTSEQEGRPARGGSRPYGDKPAGRARPTGDRPAGAGRAYGEKSEGSGRAYGDKPARSRPSGDRPTGGAGRSYSERSSE
GAGRAFGDKPAGARSFGGKPGGKPGAGRGGFGGKPGGKPGGRAGGGKAGGGKPAGPRGKR
>Mature_619_residues
PRTSPPRKDKNRVPRIKRELTPAAPKEAERIAKVVARAGLGSRREIEEWIEAGRVAVNGEVLTTPAVTVTAEDAITVDGA
PLPERERTRLFIYHKPRGVVTTNRDPEGRTTLFEILPQGLPRLVSVGRLDLNSEGLLLLTNDGGLARVLELPETGWLRRY
RVRANGEVNQAQLDSLLKGITVDGVEYGPIEAELDRVQGANAWITVSLREGKNREIRNVFGALGLQVNRLIRVSYGPFQL
GDVPEGGIEEVRTRVLRDQIGNDLAAAAGADFTGLLVERELEEAPPRVALRPAGKRQAAAEKGGTLKAPARRSRQDEDFD
APVEDVIRPAGPRTRRRMSDENAVESRGSVADRKGRTVKVERVVAPKADAPTRGARTGARPGARKSDRDEAGARPFRRGP
AEGKERFSERGPARAGFRDDARGPRRERDDREDFRRRPTREGEDRPRRPRPETADGAPRRGRDERPQQGERPFRTRSERP
DRTSEQEGRPARGGSRPYGDKPAGRARPTGDRPAGAGRAYGEKSEGSGRAYGDKPARSRPSGDRPTGGAGRSYSERSSEG
AGRAFGDKPAGARSFGGKPGGKPGAGRGGFGGKPGGKPGGRAGGGKAGGGKPAGPRGKR

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=298, Percent_Identity=39.5973154362416, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081838, Length=187, Percent_Identity=34.2245989304813, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788510, Length=204, Percent_Identity=28.4313725490196, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790453, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 67006; Mature: 66875

Theoretical pI: Translated: 11.45; Mature: 11.45

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTSPPRKDKNRVPRIKRELTPAAPKEAERIAKVVARAGLGSRREIEEWIEAGRVAVNG
CCCCCCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEECC
EVLTTPAVTVTAEDAITVDGAPLPERERTRLFIYHKPRGVVTTNRDPEGRTTLFEILPQG
EEEECCEEEEEECCEEEECCCCCCCCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHH
LPRLVSVGRLDLNSEGLLLLTNDGGLARVLELPETGWLRRYRVRANGEVNQAQLDSLLKG
HHHHHHHCCEEECCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHC
ITVDGVEYGPIEAELDRVQGANAWITVSLREGKNREIRNVFGALGLQVNRLIRVSYGPFQ
CEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEEEEEECCCEE
LGDVPEGGIEEVRTRVLRDQIGNDLAAAAGADFTGLLVERELEEAPPRVALRPAGKRQAA
CCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHH
AEKGGTLKAPARRSRQDEDFDAPVEDVIRPAGPRTRRRMSDENAVESRGSVADRKGRTVK
HHCCCCCCCCHHHCCCCCCCCCCHHHHHCCCCCHHHHHCCCHHHHHHCCCHHHCCCCEEE
VERVVAPKADAPTRGARTGARPGARKSDRDEAGARPFRRGPAEGKERFSERGPARAGFRD
EEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCC
DARGPRRERDDREDFRRRPTREGEDRPRRPRPETADGAPRRGRDERPQQGERPFRTRSER
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
PDRTSEQEGRPARGGSRPYGDKPAGRARPTGDRPAGAGRAYGEKSEGSGRAYGDKPARSR
CCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSGDRPTGGAGRSYSERSSEGAGRAFGDKPAGARSFGGKPGGKPGAGRGGFGGKPGGKPG
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCC
GRAGGGKAGGGKPAGPRGKR
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRTSPPRKDKNRVPRIKRELTPAAPKEAERIAKVVARAGLGSRREIEEWIEAGRVAVNG
CCCCCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEECC
EVLTTPAVTVTAEDAITVDGAPLPERERTRLFIYHKPRGVVTTNRDPEGRTTLFEILPQG
EEEECCEEEEEECCEEEECCCCCCCCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHH
LPRLVSVGRLDLNSEGLLLLTNDGGLARVLELPETGWLRRYRVRANGEVNQAQLDSLLKG
HHHHHHHCCEEECCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHC
ITVDGVEYGPIEAELDRVQGANAWITVSLREGKNREIRNVFGALGLQVNRLIRVSYGPFQ
CEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHEEEEEEEEECCCEE
LGDVPEGGIEEVRTRVLRDQIGNDLAAAAGADFTGLLVERELEEAPPRVALRPAGKRQAA
CCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHH
AEKGGTLKAPARRSRQDEDFDAPVEDVIRPAGPRTRRRMSDENAVESRGSVADRKGRTVK
HHCCCCCCCCHHHCCCCCCCCCCHHHHHCCCCCHHHHHCCCHHHHHHCCCHHHCCCCEEE
VERVVAPKADAPTRGARTGARPGARKSDRDEAGARPFRRGPAEGKERFSERGPARAGFRD
EEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCC
DARGPRRERDDREDFRRRPTREGEDRPRRPRPETADGAPRRGRDERPQQGERPFRTRSER
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
PDRTSEQEGRPARGGSRPYGDKPAGRARPTGDRPAGAGRAYGEKSEGSGRAYGDKPARSR
CCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PSGDRPTGGAGRSYSERSSEGAGRAFGDKPAGARSFGGKPGGKPGAGRGGFGGKPGGKPG
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCC
GRAGGGKAGGGKPAGPRGKR
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA