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The map label for this gene is alsR [H]

Identifier: 154246923

GI number: 154246923

Start: 3332074

End: 3333033

Strand: Direct

Name: alsR [H]

Synonym: Xaut_2993

Alternate gene names: 154246923

Gene position: 3332074-3333033 (Clockwise)

Preceding gene: 154246922

Following gene: 154246970

Centisome position: 62.76

GC content: 60.0

Gene sequence:

>960_bases
ATGATCGAGTTGCGCCATATCCATTATTTTGTCGCAGCCGTAGAGCAGGGTAGCTTTCGCAAAGCGGCGAGGCTCTTGAA
TATTCAGGAGTCTGCGGTGAGCCGGCGCATCCGAGATCTCGAAGATCGGCTTGGAGCCTCCCTGTTTCACCGCCATTCCG
GCGGCGTGGCTCTTACAGTGGCGGGGCAGCGCTTCCTTCGCCGTGTCCGCATCGCTCTCCAGCAGATCGAGGATGGCATT
AATGATGTCGCTGCGATCGGCCGATCCGAGGATGGCATGGTCAAGATCGGCATCTTCTCATCGCTGGCATCCGGTTTCAT
GTTCGATCTGCTGAAGACGTTCGACGAGAAGCATCCACGGGTGTCAGTCGAGCTGATCGAGGGCAATCCGGCGGTTCATG
TTGCCGCAATCCGCCAGCTTCAACTCGACGTGGCGCTCATAACCGGCACAGGCGATTGGCCCGGCTGCGAAACCGAACAA
CTTTGGACGGAAGGGGTATTCGCCGTCCTGCCAACCGAGCACGGCCTTGCGAAGAAGCAGAAGGTGCGCTGGCGCGATCT
TGCCGAAGAGACCTTCATCGTCAGCGATGGGGCGCCGGGGCCGGAAATCCGCGACTATCTGGTCCAGCGTCTTGCAGACC
TCGGCCGCCATCCGAACATCCACCCTCAATATGTCGGGCGTGATGTCCTTTTATCGATGGTCGCCGTCGGGCGCGGGCTC
ACTGTGGTCAGCGAGGCGGCGACAGGGGCGCAGTTTCCCGGCATCGTCTATCGGCAGATCGTGGATGAGGTCTTGCCCTT
CAGTGCGATATGGTCGCGCAAGAACGATAACCCGGCATGCCGGAGGTTTCTCAGCCTTGCCCGAACATTGTCACGATCAG
CAAGCGCGGCAATCACGCGGTTGAATGGGGCGTCGGAGACGACTGCCTCGCCTTCGCAAAGCCTCGATCTGTCGCCATGA

Upstream 100 bases:

>100_bases
CGTAAATGACCGTGCAGATTGAAACTATACTTATTCAGATACGGGGAACCATGGTGAGGTAAGGTGCTATTCGGCAAACT
TGGAGAAAGGTGGCTCCAGT

Downstream 100 bases:

>100_bases
AGCGCTCCAGCATGGGAACGATCAGGCGCACCGGATCGGCAGCTGGCTGTCCGGCCTCGCGGCCGAGGATTTCCGCGTAG
GCGGTGAGATCCCGATGGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIELRHIHYFVAAVEQGSFRKAARLLNIQESAVSRRIRDLEDRLGASLFHRHSGGVALTVAGQRFLRRVRIALQQIEDGI
NDVAAIGRSEDGMVKIGIFSSLASGFMFDLLKTFDEKHPRVSVELIEGNPAVHVAAIRQLQLDVALITGTGDWPGCETEQ
LWTEGVFAVLPTEHGLAKKQKVRWRDLAEETFIVSDGAPGPEIRDYLVQRLADLGRHPNIHPQYVGRDVLLSMVAVGRGL
TVVSEAATGAQFPGIVYRQIVDEVLPFSAIWSRKNDNPACRRFLSLARTLSRSASAAITRLNGASETTASPSQSLDLSP

Sequences:

>Translated_319_residues
MIELRHIHYFVAAVEQGSFRKAARLLNIQESAVSRRIRDLEDRLGASLFHRHSGGVALTVAGQRFLRRVRIALQQIEDGI
NDVAAIGRSEDGMVKIGIFSSLASGFMFDLLKTFDEKHPRVSVELIEGNPAVHVAAIRQLQLDVALITGTGDWPGCETEQ
LWTEGVFAVLPTEHGLAKKQKVRWRDLAEETFIVSDGAPGPEIRDYLVQRLADLGRHPNIHPQYVGRDVLLSMVAVGRGL
TVVSEAATGAQFPGIVYRQIVDEVLPFSAIWSRKNDNPACRRFLSLARTLSRSASAAITRLNGASETTASPSQSLDLSP
>Mature_319_residues
MIELRHIHYFVAAVEQGSFRKAARLLNIQESAVSRRIRDLEDRLGASLFHRHSGGVALTVAGQRFLRRVRIALQQIEDGI
NDVAAIGRSEDGMVKIGIFSSLASGFMFDLLKTFDEKHPRVSVELIEGNPAVHVAAIRQLQLDVALITGTGDWPGCETEQ
LWTEGVFAVLPTEHGLAKKQKVRWRDLAEETFIVSDGAPGPEIRDYLVQRLADLGRHPNIHPQYVGRDVLLSMVAVGRGL
TVVSEAATGAQFPGIVYRQIVDEVLPFSAIWSRKNDNPACRRFLSLARTLSRSASAAITRLNGASETTASPSQSLDLSP

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=285, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788887, Length=301, Percent_Identity=27.5747508305648, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=29.4520547945205, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=27.4914089347079, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=32.6530612244898, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI145693105, Length=288, Percent_Identity=25.6944444444444, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786401, Length=141, Percent_Identity=32.6241134751773, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790399, Length=258, Percent_Identity=23.6434108527132, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081904, Length=215, Percent_Identity=26.5116279069767, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=195, Percent_Identity=28.7179487179487, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=24.1496598639456, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789506, Length=142, Percent_Identity=30.2816901408451, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790262, Length=282, Percent_Identity=26.241134751773, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789639, Length=136, Percent_Identity=30.8823529411765, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789204, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787128, Length=125, Percent_Identity=32, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790208, Length=278, Percent_Identity=25.1798561151079, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=211, Percent_Identity=25.5924170616114, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35066; Mature: 35066

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELRHIHYFVAAVEQGSFRKAARLLNIQESAVSRRIRDLEDRLGASLFHRHSGGVALTV
CCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGQRFLRRVRIALQQIEDGINDVAAIGRSEDGMVKIGIFSSLASGFMFDLLKTFDEKHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCC
VSVELIEGNPAVHVAAIRQLQLDVALITGTGDWPGCETEQLWTEGVFAVLPTEHGLAKKQ
EEEEEECCCCCEEHHHHHHHEEEEEEEEECCCCCCCCHHHHHHCCEEEEECCCCCCHHHH
KVRWRDLAEETFIVSDGAPGPEIRDYLVQRLADLGRHPNIHPQYVGRDVLLSMVAVGRGL
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
TVVSEAATGAQFPGIVYRQIVDEVLPFSAIWSRKNDNPACRRFLSLARTLSRSASAAITR
CEEHHCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LNGASETTASPSQSLDLSP
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIELRHIHYFVAAVEQGSFRKAARLLNIQESAVSRRIRDLEDRLGASLFHRHSGGVALTV
CCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGQRFLRRVRIALQQIEDGINDVAAIGRSEDGMVKIGIFSSLASGFMFDLLKTFDEKHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCC
VSVELIEGNPAVHVAAIRQLQLDVALITGTGDWPGCETEQLWTEGVFAVLPTEHGLAKKQ
EEEEEECCCCCEEHHHHHHHEEEEEEEEECCCCCCCCHHHHHHCCEEEEECCCCCCHHHH
KVRWRDLAEETFIVSDGAPGPEIRDYLVQRLADLGRHPNIHPQYVGRDVLLSMVAVGRGL
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
TVVSEAATGAQFPGIVYRQIVDEVLPFSAIWSRKNDNPACRRFLSLARTLSRSASAAITR
CEEHHCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LNGASETTASPSQSLDLSP
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]