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The map label for this gene is fbcH [H]

Identifier: 154246893

GI number: 154246893

Start: 3283776

End: 3285050

Strand: Direct

Name: fbcH [H]

Synonym: Xaut_2958

Alternate gene names: 154246893

Gene position: 3283776-3285050 (Clockwise)

Preceding gene: 154246892

Following gene: 154246896

Centisome position: 61.85

GC content: 62.59

Gene sequence:

>1275_bases
ATGGAAGGACATTCCACCTACCAGCCCAAGGGGAAGGTCGCGCAGTGGTTCGAAAGCCGCTTGCCGATCGTCGGGCTGAT
TCATTCCTCGGCCATCGCCTATCCGGTGCCGAAGAATCTCAATTACATGTGGACCTTCGGTGCCATCCTGAGCTTGATGC
TGGTCTGCCAGATCATCTCCGGCGTGGTGCTCGCCATGCACTATGTGGCGTATGCGCCGGTGGCTTTCGAGCGCGTCGAG
CACATCATGCGCGACGTGAGCTACGGCTGGCTGATCCGTTACATCCACGCCAACGGCGCCTCCATGTTCTTCATGGCGGT
CTACATCCACATGTTCCGCGGCATGTATTACGGGTCCTACAAGGCCCCCCGCGAAGTGCTGTGGATCCTCGGCGTGATCA
TCTACCTGCTCATGATGGCCACCGGCTTCATGGGCTACGTGCTGCCCTGGGGCCAGATGTCCTTCTGGGGCGCCACCGTG
ATCACCAACCTGTTCTCGGCCATCCCGCTGGTGGGTGAGACCATCGTGCAGTGGCTCTGGGGTGGCTATTCGGTGGGCGC
GCCCACGCTGAACCGCTTCTTCTCGCTCCACTACCTGCTGCCGTTCATGATCGCCGGCGTGGTTGGCCTGCACATCTGGG
CGCTCCACCATGTGGGCCAGAACAACCCGGACGGCGTCGACATCAAGAACGTGGCCAAGGATTCGGTGCCCTTCACCCCC
TACGCCACGATCAAGGACACCTTCGCGATGGTGGTGTTCCTGATTTTCTTCTCCTGGTTCATCTTCTACATCCCGAACTA
TCTCGGCCACTCGGACAACTACATCCCGGCCAACCCGCTCTCGACCCCGGCCCACATCGTGCCCGAATGGTATTACCTGC
CGTTCTACGCGATCCTGCGCTCGGTGCCGGACAAGCTGGGCGGCGTGCTGGCCATGTTCGCGGCCATCGCAGTGCTGGCG
TTCCTGCCCTGGCTCGACACCTCCAAGGTGCGCTCGGCCAAGTATCGCCCGCTGTTCCGGCAGTTCTTCTGGGTGTTCGC
GGCGGTGTCCGTCGGTCTCGGCTATCTCGGCTCGCAGCCGGCCGAGGGCGGCTACGTCATCGCCTCGCGCATCTTCACCG
TCTATTACTTTGCCCACTTCCTCGTCATCCTGCCGCTGCTCGGCCTGTTCGAACGTCCGAAGCCTGTGCCGGCCTCCATC
GCGGACGCCGTCCTTGCCAAGAGCAAGGGTGGAGCGGTGGTGGTCGCCGGTGCGGCCGGCCCCGAGACCAAGTGA

Upstream 100 bases:

>100_bases
CCGCTCAACCTCGCGCTCCCGCCCTACACCTTCACCACCGACACCAAGATCGTGATCGGCTGACGCGCGCATCGTCGCCG
CTTTCAAAAAGGTTGGACCC

Downstream 100 bases:

>100_bases
GCCGGCGCGGAGAGAACAGCAATGACCATTCGTAGCAGTCTCTTCGGTGCCGTCGCGGCGGCGCTCCTCCTGGCCTCGGG
CACGGCCGGCGCGCTGGCGT

Product: cytochrome b/b6 domain-containing protein

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MEGHSTYQPKGKVAQWFESRLPIVGLIHSSAIAYPVPKNLNYMWTFGAILSLMLVCQIISGVVLAMHYVAYAPVAFERVE
HIMRDVSYGWLIRYIHANGASMFFMAVYIHMFRGMYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAIPLVGETIVQWLWGGYSVGAPTLNRFFSLHYLLPFMIAGVVGLHIWALHHVGQNNPDGVDIKNVAKDSVPFTP
YATIKDTFAMVVFLIFFSWFIFYIPNYLGHSDNYIPANPLSTPAHIVPEWYYLPFYAILRSVPDKLGGVLAMFAAIAVLA
FLPWLDTSKVRSAKYRPLFRQFFWVFAAVSVGLGYLGSQPAEGGYVIASRIFTVYYFAHFLVILPLLGLFERPKPVPASI
ADAVLAKSKGGAVVVAGAAGPETK

Sequences:

>Translated_424_residues
MEGHSTYQPKGKVAQWFESRLPIVGLIHSSAIAYPVPKNLNYMWTFGAILSLMLVCQIISGVVLAMHYVAYAPVAFERVE
HIMRDVSYGWLIRYIHANGASMFFMAVYIHMFRGMYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAIPLVGETIVQWLWGGYSVGAPTLNRFFSLHYLLPFMIAGVVGLHIWALHHVGQNNPDGVDIKNVAKDSVPFTP
YATIKDTFAMVVFLIFFSWFIFYIPNYLGHSDNYIPANPLSTPAHIVPEWYYLPFYAILRSVPDKLGGVLAMFAAIAVLA
FLPWLDTSKVRSAKYRPLFRQFFWVFAAVSVGLGYLGSQPAEGGYVIASRIFTVYYFAHFLVILPLLGLFERPKPVPASI
ADAVLAKSKGGAVVVAGAAGPETK
>Mature_424_residues
MEGHSTYQPKGKVAQWFESRLPIVGLIHSSAIAYPVPKNLNYMWTFGAILSLMLVCQIISGVVLAMHYVAYAPVAFERVE
HIMRDVSYGWLIRYIHANGASMFFMAVYIHMFRGMYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAIPLVGETIVQWLWGGYSVGAPTLNRFFSLHYLLPFMIAGVVGLHIWALHHVGQNNPDGVDIKNVAKDSVPFTP
YATIKDTFAMVVFLIFFSWFIFYIPNYLGHSDNYIPANPLSTPAHIVPEWYYLPFYAILRSVPDKLGGVLAMFAAIAVLA
FLPWLDTSKVRSAKYRPLFRQFFWVFAAVSVGLGYLGSQPAEGGYVIASRIFTVYYFAHFLVILPLLGLFERPKPVPASI
ADAVLAKSKGGAVVVAGAAGPETK

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=371, Percent_Identity=49.5956873315364, Blast_Score=354, Evalue=7e-98,
Organism=Saccharomyces cerevisiae, GI6226529, Length=369, Percent_Identity=53.1165311653117, Blast_Score=368, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226532, Length=248, Percent_Identity=52.0161290322581, Blast_Score=256, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6226531, Length=165, Percent_Identity=55.7575757575758, Blast_Score=189, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6226530, Length=149, Percent_Identity=48.3221476510067, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 47353; Mature: 47353

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]