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The map label for this gene is ttuB [H]

Identifier: 154246861

GI number: 154246861

Start: 3249815

End: 3251155

Strand: Reverse

Name: ttuB [H]

Synonym: Xaut_2926

Alternate gene names: 154246861

Gene position: 3251155-3249815 (Counterclockwise)

Preceding gene: 154246863

Following gene: 154246860

Centisome position: 61.24

GC content: 67.41

Gene sequence:

>1341_bases
ATGACGGAGCCCGAGGTGTCCGCCGTCGAGCGGTCGGCCATTTCCAAGGTCTCGTGGCGGCTGACGCCGTTCATCGGCCT
GATGTTCTTCATCAACTTCCTGGATCGCACCGCCGTGTCCTTCGCCGGACCCAACGGCATGTCGCGCGATCTCGGCCTCA
CCGCGTCCCAGTTCGGGTTCGCGGCGGGCATCTTTTTCCTCGGCTACATCCTGCTGGAAGTGCCGAGCAACCTGGCCCTG
CACAAGTTCGGCGCCCGCCGCTGGCTCGCCCGCATCATGGTGACCTGGGGCATCGTCGCCCTGCTGTTCACCTGGGTGAG
CAGCGTGGAAGGCCTCTATATATTGCGCTTCCTGCTCGGCGTCGCCGAGGCGGGCTTCTTCCCCGGCGCCATCCTCTATC
TGAGCCTCTGGGTGCCGGCCCGCCACCGCAACAAGGTGCTGGCCCTGTTCTATGTGGCGCAGCCGCTCACCATCGTCATC
GGCGCGCCCTTCGCCTCGCTGCTGCTGGGCGCGGACGGCATGATGGGCCTTGCCGGCTGGCGCATCATGTTCTTCGGCGT
CGCCATTCCGGCCATCCTGGTCGGCATCGTCGCCTGGTTCTACCTGGTGGACCGACCCGCCGACGCCAAATGGCTCACCA
CCGCCGAGCGCGAGTGGCTCACCGGCGAGCTTGCCAAGGAAGAGAAGGCCAAGGCCGGCAAGCACAACATCCTTGCCTCC
GGCGCGTTGCTGAACGGGCGGGTGTGGCTTTTGTCCTTCATCTACTTCGGGCTGATCTACGGCCTTTACGCGCTGGCCTT
CTTCCTGCCCACCATCATCGGCGGCTTCGAGGCCCAGTTCGGCACCAAGTTCGACGTGATGCAGAAGGGCCTCATCACCG
CCATTCCCTACCTGCCTGCGGCCGCGGCCCTGCTGCTGTGGAGCCGGCATGCGGCGAAGACCGGGGTGAAGCCCTGGCAC
GTGGGCCTGCCGGCGCTCATCGGCGCCCTGTCCATCCCGGCGGCGCTGTTCATGAACTCGCCCGCCGCCACGGTGGCGGT
GATCACCATCACGGCCTGTGCCATCTTCTCGGCCCTGCCCAACTTCTGGGCCATCCCGGCACGCTTCCTGTCGGGGGCGG
GCGCTGCGGCAGGCATCGCCCTCATCAACACGGTGGGCAACGTGGCCGGGTTTGCGGCCCCCTTCATCACCGGAGCGGTG
AAGGACGCGACAGGCTCGTTCCAGGTCGCCATGCTGGTGGTGGGCGGCTTCATGATGCTCTCCGCCGTCCTCACCCTGGT
GGTGTCGCGGCAGCGGGACGCCGTGCCGGACGCAGCGGCGATGGCCGCCCGCTCGGCCTGA

Upstream 100 bases:

>100_bases
TACCCCGGCTTGGCGGCCCGCGTGCCGTGCTCCCGCCGGGGCAAGAAGAACAAGAAGCGCAGATGCCGCAAGATCTGCCC
CATTTCCTGGAGGAAATCCC

Downstream 100 bases:

>100_bases
AAAACAGGGGGCCGGGCGAACCGGCCCCATTCATCGGGGACCCTGTCCCGGAGTGTTGGAGATACCGGAATGAACGCGAA
GATCGCCCTGTTCGGGGCCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTEPEVSAVERSAISKVSWRLTPFIGLMFFINFLDRTAVSFAGPNGMSRDLGLTASQFGFAAGIFFLGYILLEVPSNLAL
HKFGARRWLARIMVTWGIVALLFTWVSSVEGLYILRFLLGVAEAGFFPGAILYLSLWVPARHRNKVLALFYVAQPLTIVI
GAPFASLLLGADGMMGLAGWRIMFFGVAIPAILVGIVAWFYLVDRPADAKWLTTAEREWLTGELAKEEKAKAGKHNILAS
GALLNGRVWLLSFIYFGLIYGLYALAFFLPTIIGGFEAQFGTKFDVMQKGLITAIPYLPAAAALLLWSRHAAKTGVKPWH
VGLPALIGALSIPAALFMNSPAATVAVITITACAIFSALPNFWAIPARFLSGAGAAAGIALINTVGNVAGFAAPFITGAV
KDATGSFQVAMLVVGGFMMLSAVLTLVVSRQRDAVPDAAAMAARSA

Sequences:

>Translated_446_residues
MTEPEVSAVERSAISKVSWRLTPFIGLMFFINFLDRTAVSFAGPNGMSRDLGLTASQFGFAAGIFFLGYILLEVPSNLAL
HKFGARRWLARIMVTWGIVALLFTWVSSVEGLYILRFLLGVAEAGFFPGAILYLSLWVPARHRNKVLALFYVAQPLTIVI
GAPFASLLLGADGMMGLAGWRIMFFGVAIPAILVGIVAWFYLVDRPADAKWLTTAEREWLTGELAKEEKAKAGKHNILAS
GALLNGRVWLLSFIYFGLIYGLYALAFFLPTIIGGFEAQFGTKFDVMQKGLITAIPYLPAAAALLLWSRHAAKTGVKPWH
VGLPALIGALSIPAALFMNSPAATVAVITITACAIFSALPNFWAIPARFLSGAGAAAGIALINTVGNVAGFAAPFITGAV
KDATGSFQVAMLVVGGFMMLSAVLTLVVSRQRDAVPDAAAMAARSA
>Mature_445_residues
TEPEVSAVERSAISKVSWRLTPFIGLMFFINFLDRTAVSFAGPNGMSRDLGLTASQFGFAAGIFFLGYILLEVPSNLALH
KFGARRWLARIMVTWGIVALLFTWVSSVEGLYILRFLLGVAEAGFFPGAILYLSLWVPARHRNKVLALFYVAQPLTIVIG
APFASLLLGADGMMGLAGWRIMFFGVAIPAILVGIVAWFYLVDRPADAKWLTTAEREWLTGELAKEEKAKAGKHNILASG
ALLNGRVWLLSFIYFGLIYGLYALAFFLPTIIGGFEAQFGTKFDVMQKGLITAIPYLPAAAALLLWSRHAAKTGVKPWHV
GLPALIGALSIPAALFMNSPAATVAVITITACAIFSALPNFWAIPARFLSGAGAAAGIALINTVGNVAGFAAPFITGAVK
DATGSFQVAMLVVGGFMMLSAVLTLVVSRQRDAVPDAAAMAARSA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=286, Percent_Identity=25.1748251748252, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=429, Percent_Identity=34.965034965035, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI2367379, Length=444, Percent_Identity=24.7747747747748, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789152, Length=452, Percent_Identity=24.5575221238938, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789515, Length=421, Percent_Identity=24.7030878859857, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=206, Percent_Identity=26.2135922330097, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=256, Percent_Identity=23.828125, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=209, Percent_Identity=26.7942583732057, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=270, Percent_Identity=22.5925925925926, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322973, Length=348, Percent_Identity=22.7011494252874, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641682, Length=384, Percent_Identity=23.9583333333333, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639764, Length=397, Percent_Identity=23.1738035264484, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24654215, Length=400, Percent_Identity=22, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922400, Length=266, Percent_Identity=23.3082706766917, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47614; Mature: 47483

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPEVSAVERSAISKVSWRLTPFIGLMFFINFLDRTAVSFAGPNGMSRDLGLTASQFGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AAGIFFLGYILLEVPSNLALHKFGARRWLARIMVTWGIVALLFTWVSSVEGLYILRFLLG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAEAGFFPGAILYLSLWVPARHRNKVLALFYVAQPLTIVIGAPFASLLLGADGMMGLAGW
HHHCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHCCHHEEEECCHHHHHHCCCCCHHHHHH
RIMFFGVAIPAILVGIVAWFYLVDRPADAKWLTTAEREWLTGELAKEEKAKAGKHNILAS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEC
GALLNGRVWLLSFIYFGLIYGLYALAFFLPTIIGGFEAQFGTKFDVMQKGLITAIPYLPA
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHH
AAALLLWSRHAAKTGVKPWHVGLPALIGALSIPAALFMNSPAATVAVITITACAIFSALP
HHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
NFWAIPARFLSGAGAAAGIALINTVGNVAGFAAPFITGAVKDATGSFQVAMLVVGGFMML
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SAVLTLVVSRQRDAVPDAAAMAARSA
HHHHHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
TEPEVSAVERSAISKVSWRLTPFIGLMFFINFLDRTAVSFAGPNGMSRDLGLTASQFGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AAGIFFLGYILLEVPSNLALHKFGARRWLARIMVTWGIVALLFTWVSSVEGLYILRFLLG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAEAGFFPGAILYLSLWVPARHRNKVLALFYVAQPLTIVIGAPFASLLLGADGMMGLAGW
HHHCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHCCHHEEEECCHHHHHHCCCCCHHHHHH
RIMFFGVAIPAILVGIVAWFYLVDRPADAKWLTTAEREWLTGELAKEEKAKAGKHNILAS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEC
GALLNGRVWLLSFIYFGLIYGLYALAFFLPTIIGGFEAQFGTKFDVMQKGLITAIPYLPA
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHH
AAALLLWSRHAAKTGVKPWHVGLPALIGALSIPAALFMNSPAATVAVITITACAIFSALP
HHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
NFWAIPARFLSGAGAAAGIALINTVGNVAGFAAPFITGAVKDATGSFQVAMLVVGGFMML
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SAVLTLVVSRQRDAVPDAAAMAARSA
HHHHHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]