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The map label for this gene is iorA [H]

Identifier: 154246852

GI number: 154246852

Start: 3240378

End: 3240839

Strand: Reverse

Name: iorA [H]

Synonym: Xaut_2917

Alternate gene names: 154246852

Gene position: 3240839-3240378 (Counterclockwise)

Preceding gene: 154246857

Following gene: 154246851

Centisome position: 61.05

GC content: 69.7

Gene sequence:

>462_bases
ATGGCCGTCACACTCACAGTGAACGGACAGGCGCGCACCGTCGACGCCGATCCCGATACCCCGCTGCTCTGGGTCCTGCG
CGACGAGCTTGATCTCGTCGGCACCAAGTTCGGCTGCGGCCAGGCCCTGTGCGGCGCCTGCACCGTGCATCTCGACGGCA
CCCCGGTGAGGTCCTGCCAGACCGCGCTCGGCGATGTCGGCGACGGCAAGGTCGTCACCATCGAAGGCATCCAGGGCCGC
GAGGCCGAGGCGGTCCGCGCCGCCTGGGTCAGCCTCGACGTGGTCCAGTGCGGCTATTGCCAGTCCGGGCAGATCATGTC
CGCCGTGGCGCTGCTGGCCGAGAACAAGAAGCCTACCGATCCCGACATTGACGCGGCGATGGACGGCAATGTCTGCCGCT
GCGCCACCTACCACCGCATCCGCGCCGCGATCCACGACGCGGCCCGCCGGCTGGAGGCCTGA

Upstream 100 bases:

>100_bases
TCGGGGCGACGCCATGGCGCCTTTGAGGCGCGTCGCGTGCGCGCCTTCTTCTCCTATCAAGCACAGATGCGGCTGTGCCT
CTCGCAACAACGAGGTACCC

Downstream 100 bases:

>100_bases
TCCATGCACATGCTACAGAAGCTGGAGCCGGGCGTCGTGTCCGGCCTTGCCGCCGCGCTGTCCGGCGCGGCACAGACGCC
GCTCTCCCGCCGCTTCGTCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MAVTLTVNGQARTVDADPDTPLLWVLRDELDLVGTKFGCGQALCGACTVHLDGTPVRSCQTALGDVGDGKVVTIEGIQGR
EAEAVRAAWVSLDVVQCGYCQSGQIMSAVALLAENKKPTDPDIDAAMDGNVCRCATYHRIRAAIHDAARRLEA

Sequences:

>Translated_153_residues
MAVTLTVNGQARTVDADPDTPLLWVLRDELDLVGTKFGCGQALCGACTVHLDGTPVRSCQTALGDVGDGKVVTIEGIQGR
EAEAVRAAWVSLDVVQCGYCQSGQIMSAVALLAENKKPTDPDIDAAMDGNVCRCATYHRIRAAIHDAARRLEA
>Mature_152_residues
AVTLTVNGQARTVDADPDTPLLWVLRDELDLVGTKFGCGQALCGACTVHLDGTPVRSCQTALGDVGDGKVVTIEGIQGRE
AEAVRAAWVSLDVVQCGYCQSGQIMSAVALLAENKKPTDPDIDAAMDGNVCRCATYHRIRAAIHDAARRLEA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=38.4615384615385, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789232, Length=153, Percent_Identity=37.2549019607843, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=34.6153846153846, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=157, Percent_Identity=34.3949044585987, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=35.7142857142857, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737937, Length=147, Percent_Identity=36.0544217687075, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=30.379746835443, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647199, Length=158, Percent_Identity=30.379746835443, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647193, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16168; Mature: 16036

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTLTVNGQARTVDADPDTPLLWVLRDELDLVGTKFGCGQALCGACTVHLDGTPVRSCQ
CEEEEEECCCEEEECCCCCCCEEEEEECCHHHHCCCCCCCCCCCCEEEEEECCCCCHHHH
TALGDVGDGKVVTIEGIQGREAEAVRAAWVSLDVVQCGYCQSGQIMSAVALLAENKKPTD
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCCCCCC
PDIDAAMDGNVCRCATYHRIRAAIHDAARRLEA
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVTLTVNGQARTVDADPDTPLLWVLRDELDLVGTKFGCGQALCGACTVHLDGTPVRSCQ
EEEEEECCCEEEECCCCCCCEEEEEECCHHHHCCCCCCCCCCCCEEEEEECCCCCHHHH
TALGDVGDGKVVTIEGIQGREAEAVRAAWVSLDVVQCGYCQSGQIMSAVALLAENKKPTD
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCCCCCC
PDIDAAMDGNVCRCATYHRIRAAIHDAARRLEA
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]