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The map label for this gene is chvG [H]

Identifier: 154246785

GI number: 154246785

Start: 3175221

End: 3177029

Strand: Direct

Name: chvG [H]

Synonym: Xaut_2846

Alternate gene names: 154246785

Gene position: 3175221-3177029 (Clockwise)

Preceding gene: 154246784

Following gene: 154246786

Centisome position: 59.81

GC content: 69.82

Gene sequence:

>1809_bases
ATGACGGCGCACACCGACGAGGCCAGGGCCGACGAGATGGCTCCGGGCGGACCCGGGGCCTCCGGCGGCCGGGCCGAACG
GGGGCGCGAGCCGCGTGGCGGCGTCATCGCGTGGCTGAAGCGCGTGCGCCGCTTCGTGGCTTTCAAGGGCTTCTCCTCTC
TCACCCGGCGCATCGTGCTGCTCAACCTCGCCGGGCTGTGCGCCCTGGTGTCGGGCATCCTCTACCTGTCGGAATTCCGC
TCCGGCCTTATCGACGCGCGCATTCAGAGCCTTCTGGTGCAGGGCGAGATCATCGCTGCCGCCATCGCCTCGTCGGCGCA
GGTGGAGACCAATGCCATCACGCTCGATCCCGAGCGACTGCTGGAATTGCAGGCGGGCGAGAGCTACGGCCCCGACGACG
GCTTCGCGCCGCTGGAATTCCCCATCAATCCCGAGCGCGTCGCCCCGGTGCTGCGGCGCCTGGTGGGCCCGACCCGCACC
CGTGCCCGCATCTATGACCGCGAAGGCCAGCTCTTGCTGGATTCCCGCTCGCTCTATTCGCGCGGCGAGATCCTGCGCTA
CGACCTGCCGTCCCCCAACGAGCCCAAGCCCGGCGTGCTGGAACGAGCCTGGCAGGCGGTGCAGCTGTGGCTCGGCCGCG
GCGACCTGCCGCTCTACAAGGAGTTCGGCCCGCAGGCCGGCAAGAATTACCCCGAGGTCGCCTCGGCCGCGCTGGGCGCC
AAGGCCAGCGAGGTGCGTGTGGATGAGCGCGGGCAGGTGGTGGTCTCCGTCGCCGTGCCGGTCCAGCGCTTCCGCGCCAT
CCTCGGCGTGCTGCTGTTGTCCACCCAGAGCGGCGAGATCGACGCGGCGGTGAAGGCGGAGCGCTTCGTCATCGTCCGCG
TGTTCCTGGTGGCGGCGGTGGTGATGGTGCTGCTCTCGGTGCTGCTCGCCGGCACCATCGCCGATCCGGTGCGCAAGCTC
GCGGCGGCGGCCGAACGGGTGCGCCGGCGCATCAAGTCGCGGGTGGAGATCCCTGATTTTACCGCCCGCTCCGACGAGAT
CGGCCATCTCTCCGGCGCCCTGCGTGACATGACCGGCGCCCTCTACAACCGCATTGAGGCCATCGAGAGCTTCGCTGCGG
ACGTGGCGCACGAGCTGAAGAACCCGCTCACCTCCCTGCGCAGCGCGGTGGAGACGCTGCCGCTCGCCAAGACCGACACC
TCGCGCAACCGCCTGATGGAGGTGATCCAGCACGATGTGAAGCGGCTCGACCGCCTCATCTCCGACATCTCCGACGCCAG
CCGGCTCGATGCCGAGCTGCAGCGGCAGGAGGCGGTGAACGTCGATCTCAAGCAATTGCTGGAGATGGTGGTGGGCCTCG
CCCAGGACGTGCGCAAGGACGACGGCGTCCGCGTCTCCCTCAGCTTTGAGCGGGTGCACGGCGCGCCCGCCGATTTCCTG
GTCGCGGGCCATGCCTCGCGGCTGGGACAGGTTGTGGATAACCTGGTCTCCAACGCCCGTTCGTTCTCGCCCAACGGCGG
ATCGGTGCGCGTCACCTGCCGCCGCCTGAAGGATGGCGCCGAGATCGTGGTGGACGACGACGGCCCCGGCATTCGCCCCG
ATGCCCTCGCGCGCATCTTCGAGCGCTTCTATACCGACCGGCCGCACCAGGGGTTCGGGCAGAATTCCGGGCTCGGCCTC
TCCATCTCGCGGCAGATCGTGGAGGCCCATGGCGGCACCATCTGGGCCGAGAACCGCATGGCGACCGCCCCCGACCGCAG
TTCGCAGGTGGCCGGCGCCCGCTTCGTCGTGCGCCTGCCGACGGCCTGA

Upstream 100 bases:

>100_bases
TCGGTGGACGACAGCTTCGAGATGATCGAGACCCTGTACGGCGTCGGCTACCGGTTCAAGGAGTGAGCACCACGGCACCG
CGCCGGGGGCTCTGGACGAC

Downstream 100 bases:

>100_bases
GCCGTGAGCGCACCGGCCAGCATCCACGCCAGCTGCATCGCCATCGGCGACCTCGGGGTGCTGATCCGTGGCCCGTCCGG
CTCGGGCAAGTCGAGCCTCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MTAHTDEARADEMAPGGPGASGGRAERGREPRGGVIAWLKRVRRFVAFKGFSSLTRRIVLLNLAGLCALVSGILYLSEFR
SGLIDARIQSLLVQGEIIAAAIASSAQVETNAITLDPERLLELQAGESYGPDDGFAPLEFPINPERVAPVLRRLVGPTRT
RARIYDREGQLLLDSRSLYSRGEILRYDLPSPNEPKPGVLERAWQAVQLWLGRGDLPLYKEFGPQAGKNYPEVASAALGA
KASEVRVDERGQVVVSVAVPVQRFRAILGVLLLSTQSGEIDAAVKAERFVIVRVFLVAAVVMVLLSVLLAGTIADPVRKL
AAAAERVRRRIKSRVEIPDFTARSDEIGHLSGALRDMTGALYNRIEAIESFAADVAHELKNPLTSLRSAVETLPLAKTDT
SRNRLMEVIQHDVKRLDRLISDISDASRLDAELQRQEAVNVDLKQLLEMVVGLAQDVRKDDGVRVSLSFERVHGAPADFL
VAGHASRLGQVVDNLVSNARSFSPNGGSVRVTCRRLKDGAEIVVDDDGPGIRPDALARIFERFYTDRPHQGFGQNSGLGL
SISRQIVEAHGGTIWAENRMATAPDRSSQVAGARFVVRLPTA

Sequences:

>Translated_602_residues
MTAHTDEARADEMAPGGPGASGGRAERGREPRGGVIAWLKRVRRFVAFKGFSSLTRRIVLLNLAGLCALVSGILYLSEFR
SGLIDARIQSLLVQGEIIAAAIASSAQVETNAITLDPERLLELQAGESYGPDDGFAPLEFPINPERVAPVLRRLVGPTRT
RARIYDREGQLLLDSRSLYSRGEILRYDLPSPNEPKPGVLERAWQAVQLWLGRGDLPLYKEFGPQAGKNYPEVASAALGA
KASEVRVDERGQVVVSVAVPVQRFRAILGVLLLSTQSGEIDAAVKAERFVIVRVFLVAAVVMVLLSVLLAGTIADPVRKL
AAAAERVRRRIKSRVEIPDFTARSDEIGHLSGALRDMTGALYNRIEAIESFAADVAHELKNPLTSLRSAVETLPLAKTDT
SRNRLMEVIQHDVKRLDRLISDISDASRLDAELQRQEAVNVDLKQLLEMVVGLAQDVRKDDGVRVSLSFERVHGAPADFL
VAGHASRLGQVVDNLVSNARSFSPNGGSVRVTCRRLKDGAEIVVDDDGPGIRPDALARIFERFYTDRPHQGFGQNSGLGL
SISRQIVEAHGGTIWAENRMATAPDRSSQVAGARFVVRLPTA
>Mature_601_residues
TAHTDEARADEMAPGGPGASGGRAERGREPRGGVIAWLKRVRRFVAFKGFSSLTRRIVLLNLAGLCALVSGILYLSEFRS
GLIDARIQSLLVQGEIIAAAIASSAQVETNAITLDPERLLELQAGESYGPDDGFAPLEFPINPERVAPVLRRLVGPTRTR
ARIYDREGQLLLDSRSLYSRGEILRYDLPSPNEPKPGVLERAWQAVQLWLGRGDLPLYKEFGPQAGKNYPEVASAALGAK
ASEVRVDERGQVVVSVAVPVQRFRAILGVLLLSTQSGEIDAAVKAERFVIVRVFLVAAVVMVLLSVLLAGTIADPVRKLA
AAAERVRRRIKSRVEIPDFTARSDEIGHLSGALRDMTGALYNRIEAIESFAADVAHELKNPLTSLRSAVETLPLAKTDTS
RNRLMEVIQHDVKRLDRLISDISDASRLDAELQRQEAVNVDLKQLLEMVVGLAQDVRKDDGVRVSLSFERVHGAPADFLV
AGHASRLGQVVDNLVSNARSFSPNGGSVRVTCRRLKDGAEIVVDDDGPGIRPDALARIFERFYTDRPHQGFGQNSGLGLS
ISRQIVEAHGGTIWAENRMATAPDRSSQVAGARFVVRLPTA

Specific function: Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=30.2583025830258, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786783, Length=320, Percent_Identity=27.8125, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789403, Length=285, Percent_Identity=30.8771929824561, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=29.1845493562232, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790346, Length=288, Percent_Identity=28.4722222222222, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790861, Length=327, Percent_Identity=26.9113149847095, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790551, Length=300, Percent_Identity=29.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=337, Percent_Identity=27.893175074184, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=289, Percent_Identity=27.681660899654, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789149, Length=370, Percent_Identity=25.4054054054054, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=27.2373540856031, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788279, Length=286, Percent_Identity=26.5734265734266, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=210, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=294, Percent_Identity=25.8503401360544, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=215, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=28.8135593220339, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65500; Mature: 65369

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHTDEARADEMAPGGPGASGGRAERGREPRGGVIAWLKRVRRFVAFKGFSSLTRRIVL
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
LNLAGLCALVSGILYLSEFRSGLIDARIQSLLVQGEIIAAAIASSAQVETNAITLDPERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECHHHH
LELQAGESYGPDDGFAPLEFPINPERVAPVLRRLVGPTRTRARIYDREGQLLLDSRSLYS
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHEECCCCCEEEECHHHHC
RGEILRYDLPSPNEPKPGVLERAWQAVQLWLGRGDLPLYKEFGPQAGKNYPEVASAALGA
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCC
KASEVRVDERGQVVVSVAVPVQRFRAILGVLLLSTQSGEIDAAVKAERFVIVRVFLVAAV
CHHHCEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
VMVLLSVLLAGTIADPVRKLAAAAERVRRRIKSRVEIPDFTARSDEIGHLSGALRDMTGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LYNRIEAIESFAADVAHELKNPLTSLRSAVETLPLAKTDTSRNRLMEVIQHDVKRLDRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SDISDASRLDAELQRQEAVNVDLKQLLEMVVGLAQDVRKDDGVRVSLSFERVHGAPADFL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCHHHE
VAGHASRLGQVVDNLVSNARSFSPNGGSVRVTCRRLKDGAEIVVDDDGPGIRPDALARIF
ECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHH
ERFYTDRPHQGFGQNSGLGLSISRQIVEAHGGTIWAENRMATAPDRSSQVAGARFVVRLP
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEECC
TA
CC
>Mature Secondary Structure 
TAHTDEARADEMAPGGPGASGGRAERGREPRGGVIAWLKRVRRFVAFKGFSSLTRRIVL
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
LNLAGLCALVSGILYLSEFRSGLIDARIQSLLVQGEIIAAAIASSAQVETNAITLDPERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECHHHH
LELQAGESYGPDDGFAPLEFPINPERVAPVLRRLVGPTRTRARIYDREGQLLLDSRSLYS
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHEECCCCCEEEECHHHHC
RGEILRYDLPSPNEPKPGVLERAWQAVQLWLGRGDLPLYKEFGPQAGKNYPEVASAALGA
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHCC
KASEVRVDERGQVVVSVAVPVQRFRAILGVLLLSTQSGEIDAAVKAERFVIVRVFLVAAV
CHHHCEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
VMVLLSVLLAGTIADPVRKLAAAAERVRRRIKSRVEIPDFTARSDEIGHLSGALRDMTGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
LYNRIEAIESFAADVAHELKNPLTSLRSAVETLPLAKTDTSRNRLMEVIQHDVKRLDRLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SDISDASRLDAELQRQEAVNVDLKQLLEMVVGLAQDVRKDDGVRVSLSFERVHGAPADFL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCHHHE
VAGHASRLGQVVDNLVSNARSFSPNGGSVRVTCRRLKDGAEIVVDDDGPGIRPDALARIF
ECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCHHHHHHHH
ERFYTDRPHQGFGQNSGLGLSISRQIVEAHGGTIWAENRMATAPDRSSQVAGARFVVRLP
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEECC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407839; 11743193; 11743194 [H]