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The map label for this gene is appC [H]

Identifier: 154246702

GI number: 154246702

Start: 3060466

End: 3061359

Strand: Direct

Name: appC [H]

Synonym: Xaut_2763

Alternate gene names: 154246702

Gene position: 3060466-3061359 (Clockwise)

Preceding gene: 154246701

Following gene: 154246703

Centisome position: 57.65

GC content: 70.58

Gene sequence:

>894_bases
ATGGCCCTCCTCGATTTCGCATCCCCGCCCGTGTCGTCCCAGACGACCGCCGACGCGCCCCGCGACACGCTGCTGCGCCG
CTTGCTGCGGCGTCCCTCGGCGGTGACGGGGCTCATCATCTTCGCGCTCATCATCGCCATGGCGGCTTCGGCGGACATGG
TCTATCCCGACGACCCGCTGGACATGGTGGCCCAGCCCTTCCTCTGGCCGGGGCAGCACGCGGCCTATCCGCTGGGCACC
GACATGCTGGGGCGCGACATCGCCTCCGGCATCTTCCACGGGGCGCGGGTGTCGCTGCTCATCGGCGCGGTGGCGACGCT
GGTGTCGCTGGTGATCGGCGTCACCACCGGAGCGGTCTCGGGCTATTATGGCGGGCGCGTCGATGCCGGGCTGATGCGCG
TCACCGAGCTGTTCCAGACGGTGCCGCCGTTCCTGTTCGCCCTCGCCATCGTGGCGATCCTGCAGCCGTCCATTCCCACC
ATCACCTTCGCCATCGGCATCACCGCATGGCCGAGCCTGGCGCGGCTGGTGCGCGCGGAGGTGCTGAAGCTGCGGCACGG
GGAGATGGTGGCCGCCTCCATCGCGCTCGGCGCATCGGACGCGCGCATCATCCTCCTTCACATCCTGCCCAACACGCTGG
CGCCGGTGATCGTCTCCGCCTCCATCCTGGTGGCGAGCGCCATCCTCACGGAATCCTCCCTCGCCTTCCTCGGGCTCGGC
GATCCCAACGTGGTGAGCTGGGGCGGCATGGTGGGGGCGGGGCGCGAGGTGCTGCGGACCGACTGGTACGTGGCGACGGT
GCCGGGCCTCGCCATCGTCGCCGCCGTGCTGGCGCTGAACCTGCTCGGCGACGGCCTCAACGATGCCCTGAACCCCAAGG
GGGCGCGGCGATGA

Upstream 100 bases:

>100_bases
GTTCTGCTCGTCGGTGGTGGTGGTCATCGTCAATCTCGCGGTGGATCTCGCCTATACGGTGCTCGATCCGCGCATCGAGC
TGAGCTGAGGAGGTTTGACC

Downstream 100 bases:

>100_bases
GCGATCCCGTGCTCGCGGTGGAAAACCTGTCCATCGCCTTCGCCAGCGGGCGCACCACGCGCCGCGCGGTCCATGACCTG
TCCTTCGCCGTCAACCGCGG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MALLDFASPPVSSQTTADAPRDTLLRRLLRRPSAVTGLIIFALIIAMAASADMVYPDDPLDMVAQPFLWPGQHAAYPLGT
DMLGRDIASGIFHGARVSLLIGAVATLVSLVIGVTTGAVSGYYGGRVDAGLMRVTELFQTVPPFLFALAIVAILQPSIPT
ITFAIGITAWPSLARLVRAEVLKLRHGEMVAASIALGASDARIILLHILPNTLAPVIVSASILVASAILTESSLAFLGLG
DPNVVSWGGMVGAGREVLRTDWYVATVPGLAIVAAVLALNLLGDGLNDALNPKGARR

Sequences:

>Translated_297_residues
MALLDFASPPVSSQTTADAPRDTLLRRLLRRPSAVTGLIIFALIIAMAASADMVYPDDPLDMVAQPFLWPGQHAAYPLGT
DMLGRDIASGIFHGARVSLLIGAVATLVSLVIGVTTGAVSGYYGGRVDAGLMRVTELFQTVPPFLFALAIVAILQPSIPT
ITFAIGITAWPSLARLVRAEVLKLRHGEMVAASIALGASDARIILLHILPNTLAPVIVSASILVASAILTESSLAFLGLG
DPNVVSWGGMVGAGREVLRTDWYVATVPGLAIVAAVLALNLLGDGLNDALNPKGARR
>Mature_296_residues
ALLDFASPPVSSQTTADAPRDTLLRRLLRRPSAVTGLIIFALIIAMAASADMVYPDDPLDMVAQPFLWPGQHAAYPLGTD
MLGRDIASGIFHGARVSLLIGAVATLVSLVIGVTTGAVSGYYGGRVDAGLMRVTELFQTVPPFLFALAIVAILQPSIPTI
TFAIGITAWPSLARLVRAEVLKLRHGEMVAASIALGASDARIILLHILPNTLAPVIVSASILVASAILTESSLAFLGLGD
PNVVSWGGMVGAGREVLRTDWYVATVPGLAIVAAVLALNLLGDGLNDALNPKGARR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787760, Length=293, Percent_Identity=35.4948805460751, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1789964, Length=280, Percent_Identity=40, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=36.2637362637363, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788505, Length=295, Percent_Identity=31.864406779661, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789889, Length=221, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787549, Length=222, Percent_Identity=31.0810810810811, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30957; Mature: 30826

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00626 RCC1_2 ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLDFASPPVSSQTTADAPRDTLLRRLLRRPSAVTGLIIFALIIAMAASADMVYPDDPL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH
DMVAQPFLWPGQHAAYPLGTDMLGRDIASGIFHGARVSLLIGAVATLVSLVIGVTTGAVS
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYYGGRVDAGLMRVTELFQTVPPFLFALAIVAILQPSIPTITFAIGITAWPSLARLVRAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHH
VLKLRHGEMVAASIALGASDARIILLHILPNTLAPVIVSASILVASAILTESSLAFLGLG
HHHHHCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
DPNVVSWGGMVGAGREVLRTDWYVATVPGLAIVAAVLALNLLGDGLNDALNPKGARR
CCCEEECCCCCCCCHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
>Mature Secondary Structure 
ALLDFASPPVSSQTTADAPRDTLLRRLLRRPSAVTGLIIFALIIAMAASADMVYPDDPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH
DMVAQPFLWPGQHAAYPLGTDMLGRDIASGIFHGARVSLLIGAVATLVSLVIGVTTGAVS
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYYGGRVDAGLMRVTELFQTVPPFLFALAIVAILQPSIPTITFAIGITAWPSLARLVRAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHH
VLKLRHGEMVAASIALGASDARIILLHILPNTLAPVIVSASILVASAILTESSLAFLGLG
HHHHHCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
DPNVVSWGGMVGAGREVLRTDWYVATVPGLAIVAAVLALNLLGDGLNDALNPKGARR
CCCEEECCCCCCCCHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]