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The map label for this gene is yliI [H]

Identifier: 154246679

GI number: 154246679

Start: 3033593

End: 3034792

Strand: Direct

Name: yliI [H]

Synonym: Xaut_2740

Alternate gene names: 154246679

Gene position: 3033593-3034792 (Clockwise)

Preceding gene: 154246678

Following gene: 154246680

Centisome position: 57.14

GC content: 71.0

Gene sequence:

>1200_bases
ATGGGCGCGGTTCTTGCCCGGCGCGATCACCGGCAGCGTTCCTCTTTTCCCCGTCCCGGCCGCCGCGCCGCCATCGCTGC
GCTGGCGCTGCTCGGCCTGCTTGTCGCCGGCGCCTTTGCCTTCGCGGCCGACGATGCCGGTGCCGCGAGGCGCTTCGCCG
GCGAAGAGGTGCGCGTGGTGCCTTTCGCCTCGGGGCTGGAGCATCCCTGGAGCATGGCCTTCCTGCCGGACGGCCGCCTT
CTCGTCACCGAGCGGGATGGGCGCCTGCGCGTGATCGATTCCTCCGGAAAGCTCGGCGCGCCCATCGTCGGCGTGCCCGA
TGTGGCGGCGCGGGGGCAGGGCGGCTTGCTGGATGTGGCGCTGGGCCCCGCCTTCGCCACCAACCACCTGATCTATCTGA
GCTATGCCGAGCCCCGCCCGGACGGTGCCGGCACCTCCGTGGCGCGCGGGCGCCTCTCGGAGGACCTGACCCGGCTCACC
GACCTGCAAGTGATTTTCCGCCAGCAGCCCGCCCATTCCGGCGGCAACCATTTCGGCTCGCGCCTCGTGTTCGCGCCGGA
CGGCATGCTGTTCGTGACGCTGGGTGAGCGCTTCGACCTGATGGACAAGGCGCAGGACCTCTCCACCACCCTCGGCAAAG
TGGTGCGCATCGCGCCGGATGGCTCGATCCCGGCGGATAATCCCTTCCGCGACCGCCCCGGCGCGCGGCCTGAAATCTTC
AGCTACGGCCATCGCAACGTGCAGGCCGGCGTCATCGAGCCCGCCACCGGCCGGCTGTGGACGGTGGAGCACGGTCCGCG
CGGCGGCGACGAGGTGAACCGGCCGGAGGCGGGCAAGAACTACGGCTGGCCTATCATCGGCTACGGCCGGCATTATTCCG
GCGCCAAGATCGGCGTCGGGACGCGCAAGGAGGGCATGGAGCAGCCCCTGTTCTATTGGGATCCCTCCATCGCGCCCTCC
GGCGCGGCCTTCTACTCCGCCGACCTTTTGCCCGCGTTCAAGGGCCAGCTCTTCGTCGGCGCGCTGGCGGGGCAGGCGCT
GGTGGAGGTGAAGGTCCGCAACGGCGCCGTGACCGGCGAGGAGCAACTGCCGTTAGGCAAGCGCATCCGCGACGTGCGGC
AGGGACCGGACGGGGCGCTGTGGCTGGCCACCGACGACACCGGCGAGATCCTGCGCGTGGTGCCCGCCGCCGCCAAATGA

Upstream 100 bases:

>100_bases
AGGTCACGGACGGCCCGTGATGCCGAGTTCTTTCGCCGGCCGCGCTGAGCCGGCGATGCAGCTGCGACCCGATCCCCGTT
TCCGTACCCTGCCGCGCGAG

Downstream 100 bases:

>100_bases
GTGGCCCTGACGGGATTCCCTTGGGTCCCCATCGCTCCTAACATCGGGTCGCCGATGGCGCTTGGCTCTTGATTCCGGGC
GCCCTGTTCCGCGGAGACCC

Product: glucose sorbosone dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MGAVLARRDHRQRSSFPRPGRRAAIAALALLGLLVAGAFAFAADDAGAARRFAGEEVRVVPFASGLEHPWSMAFLPDGRL
LVTERDGRLRVIDSSGKLGAPIVGVPDVAARGQGGLLDVALGPAFATNHLIYLSYAEPRPDGAGTSVARGRLSEDLTRLT
DLQVIFRQQPAHSGGNHFGSRLVFAPDGMLFVTLGERFDLMDKAQDLSTTLGKVVRIAPDGSIPADNPFRDRPGARPEIF
SYGHRNVQAGVIEPATGRLWTVEHGPRGGDEVNRPEAGKNYGWPIIGYGRHYSGAKIGVGTRKEGMEQPLFYWDPSIAPS
GAAFYSADLLPAFKGQLFVGALAGQALVEVKVRNGAVTGEEQLPLGKRIRDVRQGPDGALWLATDDTGEILRVVPAAAK

Sequences:

>Translated_399_residues
MGAVLARRDHRQRSSFPRPGRRAAIAALALLGLLVAGAFAFAADDAGAARRFAGEEVRVVPFASGLEHPWSMAFLPDGRL
LVTERDGRLRVIDSSGKLGAPIVGVPDVAARGQGGLLDVALGPAFATNHLIYLSYAEPRPDGAGTSVARGRLSEDLTRLT
DLQVIFRQQPAHSGGNHFGSRLVFAPDGMLFVTLGERFDLMDKAQDLSTTLGKVVRIAPDGSIPADNPFRDRPGARPEIF
SYGHRNVQAGVIEPATGRLWTVEHGPRGGDEVNRPEAGKNYGWPIIGYGRHYSGAKIGVGTRKEGMEQPLFYWDPSIAPS
GAAFYSADLLPAFKGQLFVGALAGQALVEVKVRNGAVTGEEQLPLGKRIRDVRQGPDGALWLATDDTGEILRVVPAAAK
>Mature_398_residues
GAVLARRDHRQRSSFPRPGRRAAIAALALLGLLVAGAFAFAADDAGAARRFAGEEVRVVPFASGLEHPWSMAFLPDGRLL
VTERDGRLRVIDSSGKLGAPIVGVPDVAARGQGGLLDVALGPAFATNHLIYLSYAEPRPDGAGTSVARGRLSEDLTRLTD
LQVIFRQQPAHSGGNHFGSRLVFAPDGMLFVTLGERFDLMDKAQDLSTTLGKVVRIAPDGSIPADNPFRDRPGARPEIFS
YGHRNVQAGVIEPATGRLWTVEHGPRGGDEVNRPEAGKNYGWPIIGYGRHYSGAKIGVGTRKEGMEQPLFYWDPSIAPSG
AAFYSADLLPAFKGQLFVGALAGQALVEVKVRNGAVTGEEQLPLGKRIRDVRQGPDGALWLATDDTGEILRVVPAAAK

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=271, Percent_Identity=29.8892988929889, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI187936955, Length=271, Percent_Identity=29.8892988929889, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI124248546, Length=259, Percent_Identity=30.8880308880309, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787060, Length=346, Percent_Identity=50.2890173410405, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 42577; Mature: 42446

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAVLARRDHRQRSSFPRPGRRAAIAALALLGLLVAGAFAFAADDAGAARRFAGEEVRVV
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEE
PFASGLEHPWSMAFLPDGRLLVTERDGRLRVIDSSGKLGAPIVGVPDVAARGQGGLLDVA
EECCCCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCEECCCCCCCCCCCCEEEEE
LGPAFATNHLIYLSYAEPRPDGAGTSVARGRLSEDLTRLTDLQVIFRQQPAHSGGNHFGS
CCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
RLVFAPDGMLFVTLGERFDLMDKAQDLSTTLGKVVRIAPDGSIPADNPFRDRPGARPEIF
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCHHH
SYGHRNVQAGVIEPATGRLWTVEHGPRGGDEVNRPEAGKNYGWPIIGYGRHYSGAKIGVG
HCCCCCEEECEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCC
TRKEGMEQPLFYWDPSIAPSGAAFYSADLLPAFKGQLFVGALAGQALVEVKVRNGAVTGE
CCHHCCCCCCEEECCCCCCCCCCEEECCCCHHHCCCEEEEECCCCEEEEEEECCCCCCCH
EQLPLGKRIRDVRQGPDGALWLATDDTGEILRVVPAAAK
HCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCC
>Mature Secondary Structure 
GAVLARRDHRQRSSFPRPGRRAAIAALALLGLLVAGAFAFAADDAGAARRFAGEEVRVV
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEE
PFASGLEHPWSMAFLPDGRLLVTERDGRLRVIDSSGKLGAPIVGVPDVAARGQGGLLDVA
EECCCCCCCCEEEECCCCEEEEEECCCEEEEEECCCCCCCCEECCCCCCCCCCCCEEEEE
LGPAFATNHLIYLSYAEPRPDGAGTSVARGRLSEDLTRLTDLQVIFRQQPAHSGGNHFGS
CCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
RLVFAPDGMLFVTLGERFDLMDKAQDLSTTLGKVVRIAPDGSIPADNPFRDRPGARPEIF
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCHHH
SYGHRNVQAGVIEPATGRLWTVEHGPRGGDEVNRPEAGKNYGWPIIGYGRHYSGAKIGVG
HCCCCCEEECEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECCC
TRKEGMEQPLFYWDPSIAPSGAAFYSADLLPAFKGQLFVGALAGQALVEVKVRNGAVTGE
CCHHCCCCCCEEECCCCCCCCCCEEECCCCHHHCCCEEEEECCCCEEEEEEECCCCCCCH
EQLPLGKRIRDVRQGPDGALWLATDDTGEILRVVPAAAK
HCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]