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The map label for this gene is engA

Identifier: 154246486

GI number: 154246486

Start: 2839603

End: 2840979

Strand: Direct

Name: engA

Synonym: Xaut_2545

Alternate gene names: 154246486

Gene position: 2839603-2840979 (Clockwise)

Preceding gene: 154246485

Following gene: 154246489

Centisome position: 53.49

GC content: 69.14

Gene sequence:

>1377_bases
ATGACCTTTTCCCTGGCCATCGTCGGGCGTCCGAACGTCGGCAAGTCCACTCTCTTCAACCGCCTCGTGGGCAAGAAGCT
CGCGCTGGTGGACGATCGCCCCGGCGTCACCCGCGACCGGCGGGAAGGGGATGCGCGCCTCGGCGACCTTTCCTTCCGCA
TCGTCGACACCGCCGGCCTCGAGGAGGCGGACGCTGCGAGCCTGGAAGGCCGCATGCGCGCCCAGACCGAGGCGGCCATC
GGCCATGCCGACGCCATCCTGTTCATGATCGACGCGCGCATCGGCCTCACCCCCACCGACCGCGCCTTTGCGGACCTCGT
GCGCAAGTGCGGCAAGCCGGTGATCCTGCTCGCCAACAAGAGCGAGGGGCGCGGCGGCGAGGCGGGGACCCTGGAAGCGT
TCGCCCTCGGCCTCGGCACGCCGCTGCCGTTCTCCGCCGAGCATGGCGAGGGCCTCTCCGACCTCTACGACGCCATCTGC
GACGCCCTGCCCGAGCAGACCCGGCCCGAGCCGGAGGAAGACGAGGACGCCGACACCGACTTTGTGGAGGAAGAGGCCGA
CGACAAGCCGCGCCGTCCCATCAAGGTGACGGTGCTGGGCCGGCCCAATGCCGGCAAGTCCACCCTCATCAACCGCCTTC
TGGGCGAGGACCGGCTGCTCACCGGTCCGGAAGCCGGCATCACCCGCGATTCCATCTCCGTGGAAGTCACCTATGCGGGC
GCCAAGCTGGAGGTGTTCGACACCGCCGGCCTGCGCAAGCGCGCGCGCATCGAGGACAAGCTGGAGAAGCTCTCCGCCGC
CGATGCCCTGCGCGCCATGAAATTCGCCGAGGTGGTGGTGCTGCTGGTGGATGCCACCCACCCCTTCGAGGAGCAGGACC
TGCGCATCGCCGACCTGGTGGCGCGGGAGGGGCGGGCCCTCGTCATCGGCTACAACAAGTCGGATCTCGTCGCCCGCGGC
GGCCTCATCACCCGCCTGCGCGAGGATGTGGACCGACTGCTGCCGCAGGTGAAGGGCGTGCCCATCGTGCCGGTGTCGGG
GCTCATGGGCCACGGGCTGGACAAGCTGGTGGCCGCCATCTCCTCCGCCCACAAGGTGTGGAACAAGCGCGTCGCCACCA
ATCCGCTGAACCGCTTCCTGCAGCAGGTGACCGACAACCATCCGCCGCCGGCGGTGTCGGGCCGGCGCATCAAGCTGCGC
TACATGACCCAGCCCAAAGCGCGGCCGCCGTCCTTCGTGCTGTTCTGCTCGCGCACCGATGCGGTGCCGGAGAGCTATAT
CCGCTATCTGGTGAACGGCCTGCGCGAGACCTTCGATCTGCCGGGCGTGCCGATCCGCCTGACGCTGCGGGAGAAGGGCA
ATCCCTACGCCGATTGA

Upstream 100 bases:

>100_bases
CCAGCTTCCGCCGCCGCCCAAGAGCGGCCAGCAATAGCGCTGACCCCTTTCTCGACCTGACCGGCCGGACGTTCGCAAGC
CTGGCCAAAGAGCCCATTTC

Downstream 100 bases:

>100_bases
CCCTGCGCAAGGGGTTATCCCACGCAGAAACCCCCGTCGCGATTGCGCGCGGGGTGAGCTGCTCCGGGCCTGAGTGGCCT
TCTATTCCGTAACGTAAAGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTFSLAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDARLGDLSFRIVDTAGLEEADAASLEGRMRAQTEAAI
GHADAILFMIDARIGLTPTDRAFADLVRKCGKPVILLANKSEGRGGEAGTLEAFALGLGTPLPFSAEHGEGLSDLYDAIC
DALPEQTRPEPEEDEDADTDFVEEEADDKPRRPIKVTVLGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTYAG
AKLEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVLLVDATHPFEEQDLRIADLVAREGRALVIGYNKSDLVARG
GLITRLREDVDRLLPQVKGVPIVPVSGLMGHGLDKLVAAISSAHKVWNKRVATNPLNRFLQQVTDNHPPPAVSGRRIKLR
YMTQPKARPPSFVLFCSRTDAVPESYIRYLVNGLRETFDLPGVPIRLTLREKGNPYAD

Sequences:

>Translated_458_residues
MTFSLAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDARLGDLSFRIVDTAGLEEADAASLEGRMRAQTEAAI
GHADAILFMIDARIGLTPTDRAFADLVRKCGKPVILLANKSEGRGGEAGTLEAFALGLGTPLPFSAEHGEGLSDLYDAIC
DALPEQTRPEPEEDEDADTDFVEEEADDKPRRPIKVTVLGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTYAG
AKLEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVLLVDATHPFEEQDLRIADLVAREGRALVIGYNKSDLVARG
GLITRLREDVDRLLPQVKGVPIVPVSGLMGHGLDKLVAAISSAHKVWNKRVATNPLNRFLQQVTDNHPPPAVSGRRIKLR
YMTQPKARPPSFVLFCSRTDAVPESYIRYLVNGLRETFDLPGVPIRLTLREKGNPYAD
>Mature_457_residues
TFSLAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDARLGDLSFRIVDTAGLEEADAASLEGRMRAQTEAAIG
HADAILFMIDARIGLTPTDRAFADLVRKCGKPVILLANKSEGRGGEAGTLEAFALGLGTPLPFSAEHGEGLSDLYDAICD
ALPEQTRPEPEEDEDADTDFVEEEADDKPRRPIKVTVLGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTYAGA
KLEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVLLVDATHPFEEQDLRIADLVAREGRALVIGYNKSDLVARGG
LITRLREDVDRLLPQVKGVPIVPVSGLMGHGLDKLVAAISSAHKVWNKRVATNPLNRFLQQVTDNHPPPAVSGRRIKLRY
MTQPKARPPSFVLFCSRTDAVPESYIRYLVNGLRETFDLPGVPIRLTLREKGNPYAD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=464, Percent_Identity=39.2241379310345, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1788919, Length=174, Percent_Identity=31.6091954022989, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367268, Length=139, Percent_Identity=34.5323741007194, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=31.2138728323699, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_XANP2 (A7IIE4)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417444.1
- ProteinModelPortal:   A7IIE4
- SMR:   A7IIE4
- STRING:   A7IIE4
- GeneID:   5423319
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2545
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   XAUT78245:XAUT_2545-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00449
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49989; Mature: 49858

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSLAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDARLGDLSFRIVDTAGL
CEEEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEECCEEEEEEECCCC
EEADAASLEGRMRAQTEAAIGHADAILFMIDARIGLTPTDRAFADLVRKCGKPVILLANK
CCCCHHHHCCHHHHHHHHHHCHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEC
SEGRGGEAGTLEAFALGLGTPLPFSAEHGEGLSDLYDAICDALPEQTRPEPEEDEDADTD
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCCCH
FVEEEADDKPRRPIKVTVLGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTYAG
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEEC
AKLEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVLLVDATHPFEEQDLRIADLV
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHH
AREGRALVIGYNKSDLVARGGLITRLREDVDRLLPQVKGVPIVPVSGLMGHGLDKLVAAI
HCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHCCHHHHHHHH
SSAHKVWNKRVATNPLNRFLQQVTDNHPPPAVSGRRIKLRYMTQPKARPPSFVLFCSRTD
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCC
AVPESYIRYLVNGLRETFDLPGVPIRLTLREKGNPYAD
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
TFSLAIVGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDARLGDLSFRIVDTAGL
EEEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEECCEEEEEEECCCC
EEADAASLEGRMRAQTEAAIGHADAILFMIDARIGLTPTDRAFADLVRKCGKPVILLANK
CCCCHHHHCCHHHHHHHHHHCHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEC
SEGRGGEAGTLEAFALGLGTPLPFSAEHGEGLSDLYDAICDALPEQTRPEPEEDEDADTD
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCCCH
FVEEEADDKPRRPIKVTVLGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTYAG
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEEC
AKLEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVLLVDATHPFEEQDLRIADLV
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHH
AREGRALVIGYNKSDLVARGGLITRLREDVDRLLPQVKGVPIVPVSGLMGHGLDKLVAAI
HCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHCCHHHHHHHH
SSAHKVWNKRVATNPLNRFLQQVTDNHPPPAVSGRRIKLRYMTQPKARPPSFVLFCSRTD
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCC
AVPESYIRYLVNGLRETFDLPGVPIRLTLREKGNPYAD
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA