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The map label for this gene is btrW [H]

Identifier: 154246468

GI number: 154246468

Start: 2824673

End: 2825116

Strand: Direct

Name: btrW [H]

Synonym: Xaut_2527

Alternate gene names: 154246468

Gene position: 2824673-2825116 (Clockwise)

Preceding gene: 154246467

Following gene: 154246469

Centisome position: 53.21

GC content: 67.12

Gene sequence:

>444_bases
ATGCCCGCGCTGCTCGCCGAGAGCCTGATCTCCTCCCTCGATGTGGAGGCCCGCATCGACGACATCACCAAGGCGACCGG
CTGGCTCGGCGCCCTCGCCGAGGATGAGGGCTGGTCGCAGGCGACCCAGTTCGCGCTGGAGCTGTCGCTGGAAGAGGCGC
TGACCAATGTGGTGTCCTACGGCTTCCAGGACAGCACTGTGGTCCCGCATATCCGCATCGAATGCTACCGCCTGCCGGAG
GGACGGGTAGCGGTGCGCCTGATCGACAACGGCGTCGCGTTCGATCCCACCACCATCGCCGAGCCGGAGGTGCCCGCCTC
CATCGAGGACGCCAAGATCGGCGGCCATGGCGTGCAGCTCATGCGCAACTTCCTCGAAACCCTCGCCTATGCCCGCGAGG
GCGGGGAAAACCACCTGACCCTCATCGCCGGCAAGCCGGACTGA

Upstream 100 bases:

>100_bases
CTGGTCGCAACCGGCGTGCACCAGCTGGTGGCGATCCACGCCACGCGGGATGAGGCGCTCGCCGCGGCGGGCTCCTCCAG
CGGCACGTGACGGGGCGCCC

Downstream 100 bases:

>100_bases
GTCCGCGCCCCGGAAGGGCACAGGACGGGCGATGGCTCCCGGCCGGGCGCCGCGCGGCGCCTTTGCGCGCGAGACTGTTC
CAGCCCCACCCTTTCCCGCC

Product: putative anti-sigma regulatory factor, serine/threonine protein kinase

Products: NA

Alternate protein names: Anti-sigma factor; Sigma negative effector BtrW [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MPALLAESLISSLDVEARIDDITKATGWLGALAEDEGWSQATQFALELSLEEALTNVVSYGFQDSTVVPHIRIECYRLPE
GRVAVRLIDNGVAFDPTTIAEPEVPASIEDAKIGGHGVQLMRNFLETLAYAREGGENHLTLIAGKPD

Sequences:

>Translated_147_residues
MPALLAESLISSLDVEARIDDITKATGWLGALAEDEGWSQATQFALELSLEEALTNVVSYGFQDSTVVPHIRIECYRLPE
GRVAVRLIDNGVAFDPTTIAEPEVPASIEDAKIGGHGVQLMRNFLETLAYAREGGENHLTLIAGKPD
>Mature_146_residues
PALLAESLISSLDVEARIDDITKATGWLGALAEDEGWSQATQFALELSLEEALTNVVSYGFQDSTVVPHIRIECYRLPEG
RVAVRLIDNGVAFDPTTIAEPEVPASIEDAKIGGHGVQLMRNFLETLAYAREGGENHLTLIAGKPD

Specific function: Possible negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, BtrV. Upon phosphorylation of BtrV, BtrW is released and binds to an unknown partner(s) that might be sigma-B, thereby blocking its ability to

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594 [H]

Pfam domain/function: NA

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 15891; Mature: 15760

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALLAESLISSLDVEARIDDITKATGWLGALAEDEGWSQATQFALELSLEEALTNVVSY
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GFQDSTVVPHIRIECYRLPEGRVAVRLIDNGVAFDPTTIAEPEVPASIEDAKIGGHGVQL
CCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
MRNFLETLAYAREGGENHLTLIAGKPD
HHHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure 
PALLAESLISSLDVEARIDDITKATGWLGALAEDEGWSQATQFALELSLEEALTNVVSY
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GFQDSTVVPHIRIECYRLPEGRVAVRLIDNGVAFDPTTIAEPEVPASIEDAKIGGHGVQL
CCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
MRNFLETLAYAREGGENHLTLIAGKPD
HHHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]