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The map label for this gene is atpB

Identifier: 154245922

GI number: 154245922

Start: 2234440

End: 2235192

Strand: Reverse

Name: atpB

Synonym: Xaut_1979

Alternate gene names: 154245922

Gene position: 2235192-2234440 (Counterclockwise)

Preceding gene: 154245923

Following gene: 154245921

Centisome position: 42.1

GC content: 63.08

Gene sequence:

>753_bases
ATGACCGTCGATCCGATCCACCAGTTCGAGATCAAGCGCTACGTGGACCTGCTGAATTTCGGCGGCGTGCAGTTCTCCTT
CACGAACGCCGCGCTGTTCATGTTCGGCATCGTAGCTATCATCTTCTTCTTCCTCACCTTCGCCACGCGCGGCCGCACCC
TGGTGCCGGGCCGGGCCCAGTCGGCGGCGGAGATGAGCTACGAATTCATCGCCAAGATGGTGCGCGATTCGGCCGGCTCG
GAAGGCATGGTGTTCTTCCCGCTGGTGTTCTCGCTCTTCACCTTCGTGCTGGTGTCGAACGTGGTGGGGCTCATTCCCTA
CACCTTCACCGTCACCGCCCATCTGATCGTCACCGCCGCCATGGCGCTGCTGGTGATCGGCACGGTCATCGTCTACGGCT
TCGTGCGCCACGGCACCCACTTCCTGCACCTGTTCGTGCCGTCGGGCGTGCCGGCCTTCCTGCTGCCGTTCCTGGTGGTG
ATCGAGGTGGTGTCCTTCCTCTCGCGTCCCATCAGCCTGTCGCTGCGTCTGTTCGCCAACATGCTGGCGGGCCATATCGC
CCTGAAGGTGTTCGCCTTCTTCGTGGTGGGTCTCGCTTCGGCCGGCGTGGTCGGCTGGTTCGGCGCCACCCTGCCCTTCT
TCATGATCGTGGCGCTCTACGCCCTCGAACTTCTGGTCGCGATGCTGCAGGCCTACGTGTTCGCGGTGCTCACCTCGATC
TACCTCAACGACGCGATCCATCCCGGTCACTGA

Upstream 100 bases:

>100_bases
TGGCGACCGTTCCGGTCGTCTCGTCGATTAGGCCGTCGCGGCTTATGGCCGTGATCTTTGGTTCCTGCGGCTTGGCCGCA
TTGGCAGGGGGCGCGTTCGG

Downstream 100 bases:

>100_bases
CCGGGCGGCGCATCGCAAATCCCCAAATCCAAAGCGTTCTCAAGGAGCAGTCCCATGGATCCCGCAGCTGGAAAGTTCAT
CGGTGCCGGTCTCGCCTGCC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTVDPIHQFEIKRYVDLLNFGGVQFSFTNAALFMFGIVAIIFFFLTFATRGRTLVPGRAQSAAEMSYEFIAKMVRDSAGS
EGMVFFPLVFSLFTFVLVSNVVGLIPYTFTVTAHLIVTAAMALLVIGTVIVYGFVRHGTHFLHLFVPSGVPAFLLPFLVV
IEVVSFLSRPISLSLRLFANMLAGHIALKVFAFFVVGLASAGVVGWFGATLPFFMIVALYALELLVAMLQAYVFAVLTSI
YLNDAIHPGH

Sequences:

>Translated_250_residues
MTVDPIHQFEIKRYVDLLNFGGVQFSFTNAALFMFGIVAIIFFFLTFATRGRTLVPGRAQSAAEMSYEFIAKMVRDSAGS
EGMVFFPLVFSLFTFVLVSNVVGLIPYTFTVTAHLIVTAAMALLVIGTVIVYGFVRHGTHFLHLFVPSGVPAFLLPFLVV
IEVVSFLSRPISLSLRLFANMLAGHIALKVFAFFVVGLASAGVVGWFGATLPFFMIVALYALELLVAMLQAYVFAVLTSI
YLNDAIHPGH
>Mature_249_residues
TVDPIHQFEIKRYVDLLNFGGVQFSFTNAALFMFGIVAIIFFFLTFATRGRTLVPGRAQSAAEMSYEFIAKMVRDSAGSE
GMVFFPLVFSLFTFVLVSNVVGLIPYTFTVTAHLIVTAAMALLVIGTVIVYGFVRHGTHFLHLFVPSGVPAFLLPFLVVI
EVVSFLSRPISLSLRLFANMLAGHIALKVFAFFVVGLASAGVVGWFGATLPFFMIVALYALELLVAMLQAYVFAVLTSIY
LNDAIHPGH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Homo sapiens, GI251831112, Length=207, Percent_Identity=29.951690821256, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790176, Length=220, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6226527, Length=258, Percent_Identity=32.1705426356589, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_XANP2 (A7IGT0)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416880.1
- ProteinModelPortal:   A7IGT0
- SMR:   A7IGT0
- STRING:   A7IGT0
- GeneID:   5424887
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_1979
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   RFANTVE
- ProtClustDB:   PRK05815
- BioCyc:   XAUT78245:XAUT_1979-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27394; Mature: 27263

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x102b338c)-; HASH(0xf882364)-; HASH(0x1004eda0)-; HASH(0x10d1e370)-; HASH(0xfdde87c)-; HASH(0x10c52fb0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCH
>Mature Secondary Structure 
TVDPIHQFEIKRYVDLLNFGGVQFSFTNAALFMFGIVAIIFFFLTFATRGRTLVPGRAQ
CCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCH
SAAEMSYEFIAKMVRDSAGSEGMVFFPLVFSLFTFVLVSNVVGLIPYTFTVTAHLIVTAA
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALLVIGTVIVYGFVRHGTHFLHLFVPSGVPAFLLPFLVVIEVVSFLSRPISLSLRLFAN
HHHHHHHHHHHHHHHHHCHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MLAGHIALKVFAFFVVGLASAGVVGWFGATLPFFMIVALYALELLVAMLQAYVFAVLTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLNDAIHPGH
HHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA