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The map label for this gene is sdhB [H]

Identifier: 154245907

GI number: 154245907

Start: 2221157

End: 2221942

Strand: Reverse

Name: sdhB [H]

Synonym: Xaut_1964

Alternate gene names: 154245907

Gene position: 2221942-2221157 (Counterclockwise)

Preceding gene: 154245908

Following gene: 154245906

Centisome position: 41.85

GC content: 65.65

Gene sequence:

>786_bases
ATGGTTGAGCTCACCCTCCCGAAGAACTCCCAGATCACGCCCGGCAAGGTGTGGCCGAAGCCGCAGGGCGCCAAGAAGCT
GACCGAGTTCCGCATCTATCGCTGGAACCCGGACGACGGCCGCAACCCGCGGGTCGACACCTATTATGTCGACCGCGAGG
ATTGCGGGCCCATGGTTCTCGACGGCCTGATCTGGATCAAGAACACCGTCGATCCCACCCTCACCTTCCGCCGGTCCTGC
CGCGAGGGCGTGTGCGGCTCGTGCGCCATGAACATCGGCGGCACCAACACTTTGGCCTGCACCAAGGGCATGGACGAGGT
GCTGGTGAAGGGCGTGGTCAACATCTATCCGCTGCCGCACATGCCGGTGGTGAAGGACCTGGTGCCGGACCTCACCCATT
TCTACGCCCAGCACGCCTCCATCGAGCCGTGGCTGCAGACCGACAGCCCGCCCCCCGAGAAGGAGTGGCGCCAGGCCAAG
GACGACCGCGAGAAGCTGGACGGCCTCTACGAGTGCATCCTGTGCGCCTGCTGCTCCACCTCCTGCCCCAGCTACTGGTG
GAACGGCGACCGCTACCTCGGCCCGGCGGCCCTGCTCCAGGCCACCCGCTGGCTGAAGGACAGCCGCGACGAGCGCACCG
GCGCCCGGCTCGATTATCTGGAAGACCCCTTCCGGCTGTATCGCTGCCATACCATCATGAACTGCGCCCAGGCGTGCCCG
AAGAGCCTCAACCCGGCCAAGGCCATCGCCGAGATCAAGAAGATGATGGTCGAGCGCCAGATCTGA

Upstream 100 bases:

>100_bases
TCATCGCGACCGCGCGCGGCACGGGCTGGAATGCCCACCGCGCGCGGCCATGGCCAGAAATCCTGCGGGCGGTTACCGCT
CCAGCGTTCCAGGACGTCCC

Downstream 100 bases:

>100_bases
CGGCACGCGATCGCGCCTTTTCAAAAGGCCGCCCGCCCCTGGCGTGGCGGCCTTTTGCTTGCGGATCGCTCCCCGGCGTG
GTGCTCAGCAGGCCGCCAGG

Product: succinate dehydrogenase and fumarate reductase iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MVELTLPKNSQITPGKVWPKPQGAKKLTEFRIYRWNPDDGRNPRVDTYYVDREDCGPMVLDGLIWIKNTVDPTLTFRRSC
REGVCGSCAMNIGGTNTLACTKGMDEVLVKGVVNIYPLPHMPVVKDLVPDLTHFYAQHASIEPWLQTDSPPPEKEWRQAK
DDREKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQATRWLKDSRDERTGARLDYLEDPFRLYRCHTIMNCAQACP
KSLNPAKAIAEIKKMMVERQI

Sequences:

>Translated_261_residues
MVELTLPKNSQITPGKVWPKPQGAKKLTEFRIYRWNPDDGRNPRVDTYYVDREDCGPMVLDGLIWIKNTVDPTLTFRRSC
REGVCGSCAMNIGGTNTLACTKGMDEVLVKGVVNIYPLPHMPVVKDLVPDLTHFYAQHASIEPWLQTDSPPPEKEWRQAK
DDREKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQATRWLKDSRDERTGARLDYLEDPFRLYRCHTIMNCAQACP
KSLNPAKAIAEIKKMMVERQI
>Mature_261_residues
MVELTLPKNSQITPGKVWPKPQGAKKLTEFRIYRWNPDDGRNPRVDTYYVDREDCGPMVLDGLIWIKNTVDPTLTFRRSC
REGVCGSCAMNIGGTNTLACTKGMDEVLVKGVVNIYPLPHMPVVKDLVPDLTHFYAQHASIEPWLQTDSPPPEKEWRQAK
DDREKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQATRWLKDSRDERTGARLDYLEDPFRLYRCHTIMNCAQACP
KSLNPAKAIAEIKKMMVERQI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=237, Percent_Identity=67.0886075949367, Blast_Score=330, Evalue=6e-91,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=52.7659574468085, Blast_Score=253, Evalue=7e-69,
Organism=Escherichia coli, GI1790596, Length=229, Percent_Identity=30.5676855895196, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17533915, Length=239, Percent_Identity=60.2510460251046, Blast_Score=306, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6322987, Length=234, Percent_Identity=62.8205128205128, Blast_Score=304, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17137106, Length=246, Percent_Identity=61.3821138211382, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24643156, Length=235, Percent_Identity=62.1276595744681, Blast_Score=308, Evalue=2e-84,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29787; Mature: 29787

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELTLPKNSQITPGKVWPKPQGAKKLTEFRIYRWNPDDGRNPRVDTYYVDREDCGPMVL
CEEEECCCCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCCEEEECHHCCCHHHH
DGLIWIKNTVDPTLTFRRSCREGVCGSCAMNIGGTNTLACTKGMDEVLVKGVVNIYPLPH
HHHHHHCCCCCHHHHHHHHHHCCCCCHHEECCCCCCCCHHHCCHHHHHHHHHHHHCCCCC
MPVVKDLVPDLTHFYAQHASIEPWLQTDSPPPEKEWRQAKDDREKLDGLYECILCACCST
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SCPSYWWNGDRYLGPAALLQATRWLKDSRDERTGARLDYLEDPFRLYRCHTIMNCAQACP
CCCCCCCCCCCEECHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
KSLNPAKAIAEIKKMMVERQI
CCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVELTLPKNSQITPGKVWPKPQGAKKLTEFRIYRWNPDDGRNPRVDTYYVDREDCGPMVL
CEEEECCCCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCCCEEEECHHCCCHHHH
DGLIWIKNTVDPTLTFRRSCREGVCGSCAMNIGGTNTLACTKGMDEVLVKGVVNIYPLPH
HHHHHHCCCCCHHHHHHHHHHCCCCCHHEECCCCCCCCHHHCCHHHHHHHHHHHHCCCCC
MPVVKDLVPDLTHFYAQHASIEPWLQTDSPPPEKEWRQAKDDREKLDGLYECILCACCST
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SCPSYWWNGDRYLGPAALLQATRWLKDSRDERTGARLDYLEDPFRLYRCHTIMNCAQACP
CCCCCCCCCCCEECHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
KSLNPAKAIAEIKKMMVERQI
CCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA