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The map label for this gene is infC

Identifier: 154245880

GI number: 154245880

Start: 2193056

End: 2193580

Strand: Reverse

Name: infC

Synonym: Xaut_1937

Alternate gene names: 154245880

Gene position: 2193580-2193056 (Counterclockwise)

Preceding gene: 154245884

Following gene: 154245879

Centisome position: 41.32

GC content: 61.9

Gene sequence:

>525_bases
ATGAGACCCGTCGCGCCGGAGAAGGATGGTCCGCGCGTCAACGAGGAAATCCGCATCCGCGAAGTCCAGCTGATCGACCA
GGATGGGCAAAACCGCGGCGTGGTGGCCATTCGCGATGCTCTCACCCTTGCGCAGGAAGCCGGCCTCGACCTTGTCGAGA
TCTCGCCGAATTCCGCGCCCCCCGTCTGCAAGATCCTCGACTACGGCCGGTTCAAATACCAGAACCAGAAGAAGGCGAGC
GAGGCCCGCAAGAAGCAGAAGGTGGTGGAGGTCAAGGAAATCAAGCTCCGCCCCGGCATCGACACCCACGATTACGAGGT
GAAGATGCGCTCCATGGAGCGCTTCTTCGAGGAAGGCGACAAGGTGAAGGTCACCCTGCGCTTCCGCGGCCGCGAGATGG
CGCACCAGGACATCGGCTTCAAGCTGCTTCAGAAGCTGAAGGAGGATGTCGCCGCCATCGCCAAGGTGGAAGCCGAGCCC
ATGCTCGAAGGCCGGCAGATGATCATGATCCTGTCGCCCAGGTGA

Upstream 100 bases:

>100_bases
AGACGCGGGTTGCGCAGACGACGGCAGGAGCCGGCGCCGTGGCCCATTCGCCTCGGGTATTTCGTCAATGTCTGAGGAGT
GAAAAGCCATTCGTCGCCCC

Downstream 100 bases:

>100_bases
TATGTTTCCCAGGTGAGCCCTTTACCCGGGTGATCGCATCGATCAGGTGATCCTCGCTGACGGCTGAGGGCACCCGACCG
AACGGGACCTGCGGCGAACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVVAIRDALTLAQEAGLDLVEISPNSAPPVCKILDYGRFKYQNQKKAS
EARKKQKVVEVKEIKLRPGIDTHDYEVKMRSMERFFEEGDKVKVTLRFRGREMAHQDIGFKLLQKLKEDVAAIAKVEAEP
MLEGRQMIMILSPR

Sequences:

>Translated_174_residues
MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVVAIRDALTLAQEAGLDLVEISPNSAPPVCKILDYGRFKYQNQKKAS
EARKKQKVVEVKEIKLRPGIDTHDYEVKMRSMERFFEEGDKVKVTLRFRGREMAHQDIGFKLLQKLKEDVAAIAKVEAEP
MLEGRQMIMILSPR
>Mature_174_residues
MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVVAIRDALTLAQEAGLDLVEISPNSAPPVCKILDYGRFKYQNQKKAS
EARKKQKVVEVKEIKLRPGIDTHDYEVKMRSMERFFEEGDKVKVTLRFRGREMAHQDIGFKLLQKLKEDVAAIAKVEAEP
MLEGRQMIMILSPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=58.5365853658537, Blast_Score=189, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19969; Mature: 19969

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVVAIRDALTLAQEAGLDLVEISPNSAP
CCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEECCCCCC
PVCKILDYGRFKYQNQKKASEARKKQKVVEVKEIKLRPGIDTHDYEVKMRSMERFFEEGD
CHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCC
KVKVTLRFRGREMAHQDIGFKLLQKLKEDVAAIAKVEAEPMLEGRQMIMILSPR
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVVAIRDALTLAQEAGLDLVEISPNSAP
CCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEECCCCCC
PVCKILDYGRFKYQNQKKASEARKKQKVVEVKEIKLRPGIDTHDYEVKMRSMERFFEEGD
CHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCC
KVKVTLRFRGREMAHQDIGFKLLQKLKEDVAAIAKVEAEPMLEGRQMIMILSPR
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA