BacMap

Definition	Xanthobacter autotrophicus Py2 chromosome, complete genome.
Accession	NC_009720
Length	5,308,934

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The map label for this gene is bdhA [H]

Identifier: 154245831

GI number: 154245831

Start: 2126436

End: 2127218

Strand: Reverse

Name: bdhA [H]

Synonym: Xaut_1887

Alternate gene names: 154245831

Gene position: 2127218-2126436 (Counterclockwise)

Preceding gene: 154245836

Following gene: 154245830

Centisome position: 40.07

GC content: 65.26

Gene sequence:

>783_bases
ATGCTCAAGGGTAAAGTCGCCGTCGTCACCGGATCCACCAGCGGAATCGGGCTCGCCTATGCCCGGGCCTTCGCCAAGGA
AGGCGCGAACATCGTGATCAACGGTCTCGGTGACGCCGCCGCCATCGAGAAGGAGCGTGCCGCGATCGAGAGCGAATTCG
GCGTGAAGTGCCTCTATTCGCCCGCCAACATGCTGAAGCCCGATGAAATCGCCGGCATGGTGCAGCTGGCCGAGACCGAG
CTGGGCGCCTGCGATATCCTCGTGAACAATGCGGGCATCCAGCATGTGGCGCCCATCGAGGAGTTCCCGATCGACACCTG
GAACACCATCATCGCCATCAACCTGTCGGCGGCCTTCTTCGCCATGCGCGCGGCCATTCCCGGCATGAAGGCGCGCAAGT
GGGGCCGCATCATCAACACTGCCTCCGCCCATGCGCTGGTGGCCTCGCCCTTCAAGTCGGCCTACGTCTCGGCCAAGCAC
GGCATCGCCGGCCTGACCAAGACCGCGGCGCTGGAGACGGCGGAATTCGGCATCACCGTCAACGCCATCTGCCCCGGCTA
CGTGTGGACGCCCCTCGTCGAGAAGCAGATCCCCGACACCGCCAAGGCCCGCGGCATGACCGAGGAGCAGGTGAAGAAGG
AGGTGATTCTCGCCGCCCAGCCCACGAAGGAATTCGTGACGGTGGAAGAGGTCGCGGCCTACGCGGTGTTCCTTGCCTCC
GACAACGCCCGCTCCATCACCGGCGCCATGCAGGTGATCGACGGCGGCTGGACCGCTGCGTGA

Upstream 100 bases:

>100_bases
CAGGTTCGCCTGTGCGCGTGACGGCACCGTCACACCGCTTCGCTAAACCGTGAGCCTCGGCCGCAGGCCGGGCCACGTCG
CGCCTTGTTGGGGAACAGCC

Downstream 100 bases:

>100_bases
GCGCGGCCCGACCCGGAGACACACCGTGAGTCGCCGCGACGGCGCCAAGCCGGTGAGCCTCGCGCTCCAGGGGGGAGGCG
CCCATGGCGCCTTCACCTGG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLKGKVAVVTGSTSGIGLAYARAFAKEGANIVINGLGDAAAIEKERAAIESEFGVKCLYSPANMLKPDEIAGMVQLAETE
LGACDILVNNAGIQHVAPIEEFPIDTWNTIIAINLSAAFFAMRAAIPGMKARKWGRIINTASAHALVASPFKSAYVSAKH
GIAGLTKTAALETAEFGITVNAICPGYVWTPLVEKQIPDTAKARGMTEEQVKKEVILAAQPTKEFVTVEEVAAYAVFLAS
DNARSITGAMQVIDGGWTAA

Sequences:

>Translated_260_residues
MLKGKVAVVTGSTSGIGLAYARAFAKEGANIVINGLGDAAAIEKERAAIESEFGVKCLYSPANMLKPDEIAGMVQLAETE
LGACDILVNNAGIQHVAPIEEFPIDTWNTIIAINLSAAFFAMRAAIPGMKARKWGRIINTASAHALVASPFKSAYVSAKH
GIAGLTKTAALETAEFGITVNAICPGYVWTPLVEKQIPDTAKARGMTEEQVKKEVILAAQPTKEFVTVEEVAAYAVFLAS
DNARSITGAMQVIDGGWTAA
>Mature_260_residues
MLKGKVAVVTGSTSGIGLAYARAFAKEGANIVINGLGDAAAIEKERAAIESEFGVKCLYSPANMLKPDEIAGMVQLAETE
LGACDILVNNAGIQHVAPIEEFPIDTWNTIIAINLSAAFFAMRAAIPGMKARKWGRIINTASAHALVASPFKSAYVSAKH
GIAGLTKTAALETAEFGITVNAICPGYVWTPLVEKQIPDTAKARGMTEEQVKKEVILAAQPTKEFVTVEEVAAYAVFLAS
DNARSITGAMQVIDGGWTAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=31.5384615384615, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=30.859375, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI4504505, Length=260, Percent_Identity=30.3846153846154, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI20149619, Length=251, Percent_Identity=28.2868525896414, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI15277342, Length=273, Percent_Identity=29.3040293040293, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=28.0898876404494, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=30.6532663316583, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=28.0632411067194, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758504, Length=204, Percent_Identity=29.9019607843137, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=28.6919831223629, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=26.5625, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI142976729, Length=221, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7706318, Length=226, Percent_Identity=27.4336283185841, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI5031737, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=31.3131313131313, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705925, Length=261, Percent_Identity=28.735632183908, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=30.0546448087432, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4503301, Length=213, Percent_Identity=30.9859154929577, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=26.063829787234, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=28.042328042328, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=24.6073298429319, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI223718074, Length=114, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7705855, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=28.9017341040462, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=37.6425855513308, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=31.8007662835249, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=32.8125, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=33.4630350194552, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=34.2307692307692, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=32.3076923076923, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.4615384615385, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=27.734375, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=29.6577946768061, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=261, Percent_Identity=27.9693486590038, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787820, Length=139, Percent_Identity=29.4964028776978, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=262, Percent_Identity=32.0610687022901, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=28.2442748091603, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=269, Percent_Identity=28.6245353159851, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.906976744186, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=277, Percent_Identity=32.8519855595668, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=263, Percent_Identity=28.5171102661597, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=31.0880829015544, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=26.7175572519084, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=29.9270072992701, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=284, Percent_Identity=31.6901408450704, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=28.2828282828283, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=29.2418772563177, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=31.5018315018315, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=30.5164319248826, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=29.8181818181818, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=30.03663003663, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=275, Percent_Identity=30.1818181818182, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=27.4809160305344, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=274, Percent_Identity=32.4817518248175, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=275, Percent_Identity=28, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=266, Percent_Identity=28.1954887218045, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=27.0992366412214, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=31.3653136531365, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=280, Percent_Identity=29.2857142857143, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=227, Percent_Identity=28.1938325991189, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=265, Percent_Identity=28.6792452830189, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=262, Percent_Identity=27.0992366412214, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=30.2904564315353, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=31.1787072243346, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24644339, Length=269, Percent_Identity=31.5985130111524, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.5019305019305, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=33.0769230769231, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=33.5, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24639444, Length=268, Percent_Identity=31.3432835820896, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=29.1187739463602, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=32.3076923076923, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=32.3076923076923, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640442, Length=198, Percent_Identity=30.8080808080808, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.25, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.25, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=243, Percent_Identity=23.0452674897119, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737361, Length=208, Percent_Identity=30.2884615384615, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=262, Percent_Identity=25.5725190839695, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644337, Length=199, Percent_Identity=30.6532663316583, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=27.2251308900524, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=28.4023668639053, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=242, Percent_Identity=28.9256198347107, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571387, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356301, Length=229, Percent_Identity=26.2008733624454, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281364892, Length=240, Percent_Identity=24.5833333333333, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27325; Mature: 27325

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGKVAVVTGSTSGIGLAYARAFAKEGANIVINGLGDAAAIEKERAAIESEFGVKCLYS
CCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEC
PANMLKPDEIAGMVQLAETELGACDILVNNAGIQHVAPIEEFPIDTWNTIIAINLSAAFF
CHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCCCEEEEEEHHHHHH
AMRAAIPGMKARKWGRIINTASAHALVASPFKSAYVSAKHGIAGLTKTAALETAEFGITV
HHHHHCCCCHHHHHHHHHCCCCCHHEEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCEEE
NAICPGYVWTPLVEKQIPDTAKARGMTEEQVKKEVILAAQPTKEFVTVEEVAAYAVFLAS
EEECCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHEEEEECCCHHHHHHHHHHEEEEEEEC
DNARSITGAMQVIDGGWTAA
CCCCHHHHHHHEECCCCCCC
>Mature Secondary Structure
MLKGKVAVVTGSTSGIGLAYARAFAKEGANIVINGLGDAAAIEKERAAIESEFGVKCLYS
CCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEC
PANMLKPDEIAGMVQLAETELGACDILVNNAGIQHVAPIEEFPIDTWNTIIAINLSAAFF
CHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHCCCCCCCEEEEEEHHHHHH
AMRAAIPGMKARKWGRIINTASAHALVASPFKSAYVSAKHGIAGLTKTAALETAEFGITV
HHHHHCCCCHHHHHHHHHCCCCCHHEEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCEEE
NAICPGYVWTPLVEKQIPDTAKARGMTEEQVKKEVILAAQPTKEFVTVEEVAAYAVFLAS
EEECCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHEEEEECCCHHHHHHHHHHEEEEEEEC
DNARSITGAMQVIDGGWTAA
CCCCHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]