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The map label for this gene is fur [H]

Identifier: 154245764

GI number: 154245764

Start: 2048113

End: 2048547

Strand: Reverse

Name: fur [H]

Synonym: Xaut_1820

Alternate gene names: 154245764

Gene position: 2048547-2048113 (Counterclockwise)

Preceding gene: 154245765

Following gene: 154245763

Centisome position: 38.59

GC content: 62.76

Gene sequence:

>435_bases
TTGAGCGGCAGCAACATGAGCGTCATCGAGGAAGCGTGCCTTGCCAAGGGCATGAGGATGACGGAGCAGCGCCGGATCAT
CGCCCGCGTGCTTTCCGGCGCGCAGGACCATCCTGACGTGGAGGAACTGCACCGCCGCGCCGTCGCCATCGACGACAACA
TCTCCATCTCCACGGTCTATCGCACGGTGAAGATGCTGGAGGATGCCGGCATCATCGAGCGCCATGATTTCGGCGACGGT
CGCGCCCGTTACGAGCAGATGCCGGACGAGCACCATGATCATCTCATCGACCTGAGATCCGGCCACGTGATCGAATTCCG
CTCCGAGGAGATCGAGGCGCTGCAGGAGGCCATCGCCCGCCGCCTCGGCTACAAGCTGCGCGGCCATCGCCTCGAACTCT
ATGCTGTGCCCCTCGAAGAGGATGAGAAATCGTGA

Upstream 100 bases:

>100_bases
CTGCTGCTGCGGCGGGATTTTTGAGGGACGTCCGCCCCCTTGCAGGGATCGGGCCGGAGGGCGATAAGGCGTCTGTCCCG
TTGGATCGCGGAGGTCCCGC

Downstream 100 bases:

>100_bases
CGCCGGCCCGCGAGCCGGCGGGCGAGGCCACGCGCCTGCCCCTTGAATTCGGCGGCCTTGAGCCCCTGGGGCCAGAGCAG
CCGGCGGTCTCGCGGTTTCT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSGSNMSVIEEACLAKGMRMTEQRRIIARVLSGAQDHPDVEELHRRAVAIDDNISISTVYRTVKMLEDAGIIERHDFGDG
RARYEQMPDEHHDHLIDLRSGHVIEFRSEEIEALQEAIARRLGYKLRGHRLELYAVPLEEDEKS

Sequences:

>Translated_144_residues
MSGSNMSVIEEACLAKGMRMTEQRRIIARVLSGAQDHPDVEELHRRAVAIDDNISISTVYRTVKMLEDAGIIERHDFGDG
RARYEQMPDEHHDHLIDLRSGHVIEFRSEEIEALQEAIARRLGYKLRGHRLELYAVPLEEDEKS
>Mature_143_residues
SGSNMSVIEEACLAKGMRMTEQRRIIARVLSGAQDHPDVEELHRRAVAIDDNISISTVYRTVKMLEDAGIIERHDFGDGR
ARYEQMPDEHHDHLIDLRSGHVIEFRSEEIEALQEAIARRLGYKLRGHRLELYAVPLEEDEKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=126, Percent_Identity=39.6825396825397, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16549; Mature: 16418

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSNMSVIEEACLAKGMRMTEQRRIIARVLSGAQDHPDVEELHRRAVAIDDNISISTVY
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
RTVKMLEDAGIIERHDFGDGRARYEQMPDEHHDHLIDLRSGHVIEFRSEEIEALQEAIAR
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHEEECCCCCEEEECHHHHHHHHHHHHH
RLGYKLRGHRLELYAVPLEEDEKS
HHCCHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SGSNMSVIEEACLAKGMRMTEQRRIIARVLSGAQDHPDVEELHRRAVAIDDNISISTVY
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
RTVKMLEDAGIIERHDFGDGRARYEQMPDEHHDHLIDLRSGHVIEFRSEEIEALQEAIAR
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHEEECCCCCEEEECHHHHHHHHHHHHH
RLGYKLRGHRLELYAVPLEEDEKS
HHCCHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]