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The map label for this gene is ycbL [H]

Identifier: 154245699

GI number: 154245699

Start: 1977932

End: 1978639

Strand: Reverse

Name: ycbL [H]

Synonym: Xaut_1755

Alternate gene names: 154245699

Gene position: 1978639-1977932 (Counterclockwise)

Preceding gene: 154245700

Following gene: 154245698

Centisome position: 37.27

GC content: 66.67

Gene sequence:

>708_bases
TTGCAACCTAACCGGAGACGGGCCACGCCCGCCGCCGGCTCCAAATGCGCTCTCGCGGAGCCCTTCATGCAGCCGATCCA
GATCGCCGTCGTCCCCGTCACGCCGTTCGAGCAGAACTGCTCGCTGTTGTGGTGCACCAGGACCATGAAGGGCGTGGTGA
TCGATCCCGGCGGCGATCTCGACAAGATCCGCTCGGCCATCGCCGAGACCGGGATCAGCGTGGACAAGATCCTTCTGACC
CACGGCCATGTGGACCACGCCGCCGGCGCCGCCGAGCTGGCCGAAACCCTCGGCGTGAAGGTGGAGGGGCCGGGGGAGGC
TGACCAGTTCATCATGGACGACATCCCCGCCACGGCCGCCAAATATGGCATCCCCAATGCCCGCGCGGTGACGCCCGACC
GCTATCTCAGCGAGGGCGAGACGGTGAGCGTGGGCGATCTCACCCTCGATATCCTGCACGTGCCCGGGCACACGCCGGGC
CATCTCGTCTTCGTGCACAAGGGCGTCGGCATCGCCATCGTGGGCGACACCCTGTTTCGCGGCTCGGTGGGGCGCACCGA
CTTTCCCTATGGCGATCCGGACCTGCTGATCGCGGGCATCGTCGGCAAGCTGCTGCCGCTGGGGGACAATGTGGTCTGCC
TGCCCGGTCATGGTCCTGTCACCAGCATCGGCGACGAAAAGGCCCACAACCCTTTTCTGCCGCGTTGA

Upstream 100 bases:

>100_bases
TCCCACGGCGACAGCGACTGACGCCGGAGGCCTTTCGTCCATCGCGGACCATCGGCCATCTTGCCGCCATCTTGCGTCCG
CGCCCATCCTGCCGGACCCT

Downstream 100 bases:

>100_bases
TTTTGCCGCGCTGACCTCTGCCCCCTGATCTTCCGCCCGTGACGCGCAAGGAGGCGCTGCCACCGTGACCGCCCCGCGCT
ATGCCCTTTATCTCGCGCCG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQPNRRRATPAAGSKCALAEPFMQPIQIAVVPVTPFEQNCSLLWCTRTMKGVVIDPGGDLDKIRSAIAETGISVDKILLT
HGHVDHAAGAAELAETLGVKVEGPGEADQFIMDDIPATAAKYGIPNARAVTPDRYLSEGETVSVGDLTLDILHVPGHTPG
HLVFVHKGVGIAIVGDTLFRGSVGRTDFPYGDPDLLIAGIVGKLLPLGDNVVCLPGHGPVTSIGDEKAHNPFLPR

Sequences:

>Translated_235_residues
MQPNRRRATPAAGSKCALAEPFMQPIQIAVVPVTPFEQNCSLLWCTRTMKGVVIDPGGDLDKIRSAIAETGISVDKILLT
HGHVDHAAGAAELAETLGVKVEGPGEADQFIMDDIPATAAKYGIPNARAVTPDRYLSEGETVSVGDLTLDILHVPGHTPG
HLVFVHKGVGIAIVGDTLFRGSVGRTDFPYGDPDLLIAGIVGKLLPLGDNVVCLPGHGPVTSIGDEKAHNPFLPR
>Mature_235_residues
MQPNRRRATPAAGSKCALAEPFMQPIQIAVVPVTPFEQNCSLLWCTRTMKGVVIDPGGDLDKIRSAIAETGISVDKILLT
HGHVDHAAGAAELAETLGVKVEGPGEADQFIMDDIPATAAKYGIPNARAVTPDRYLSEGETVSVGDLTLDILHVPGHTPG
HLVFVHKGVGIAIVGDTLFRGSVGRTDFPYGDPDLLIAGIVGKLLPLGDNVVCLPGHGPVTSIGDEKAHNPFLPR

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI116642887, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI21703352, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=49.5192307692308, Blast_Score=236, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17538952, Length=199, Percent_Identity=28.1407035175879, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330176, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356335, Length=219, Percent_Identity=25.5707762557078, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24667703, Length=219, Percent_Identity=25.5707762557078, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24698; Mature: 24698

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPNRRRATPAAGSKCALAEPFMQPIQIAVVPVTPFEQNCSLLWCTRTMKGVVIDPGGDL
CCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCH
DKIRSAIAETGISVDKILLTHGHVDHAAGAAELAETLGVKVEGPGEADQFIMDDIPATAA
HHHHHHHHHCCCCCEEEEEECCCCHHHCCHHHHHHHHCEEEECCCCCHHHHHHCCCHHHH
KYGIPNARAVTPDRYLSEGETVSVGDLTLDILHVPGHTPGHLVFVHKGVGIAIVGDTLFR
HHCCCCCCEECCHHHHCCCCEEEECCEEEEEEECCCCCCCEEEEEECCCEEEEECCHHHC
GSVGRTDFPYGDPDLLIAGIVGKLLPLGDNVVCLPGHGPVTSIGDEKAHNPFLPR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPNRRRATPAAGSKCALAEPFMQPIQIAVVPVTPFEQNCSLLWCTRTMKGVVIDPGGDL
CCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCH
DKIRSAIAETGISVDKILLTHGHVDHAAGAAELAETLGVKVEGPGEADQFIMDDIPATAA
HHHHHHHHHCCCCCEEEEEECCCCHHHCCHHHHHHHHCEEEECCCCCHHHHHHCCCHHHH
KYGIPNARAVTPDRYLSEGETVSVGDLTLDILHVPGHTPGHLVFVHKGVGIAIVGDTLFR
HHCCCCCCEECCHHHHCCCCEEEECCEEEEEEECCCCCCCEEEEEECCCEEEEECCHHHC
GSVGRTDFPYGDPDLLIAGIVGKLLPLGDNVVCLPGHGPVTSIGDEKAHNPFLPR
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]