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The map label for this gene is gldA [H]

Identifier: 154245658

GI number: 154245658

Start: 1929384

End: 1930472

Strand: Direct

Name: gldA [H]

Synonym: Xaut_1714

Alternate gene names: 154245658

Gene position: 1929384-1930472 (Clockwise)

Preceding gene: 154245657

Following gene: 154245661

Centisome position: 36.34

GC content: 70.89

Gene sequence:

>1089_bases
ATGCGCGAACTCAAGGTGTTCGGCGCCCCCGGCCTCTATGTGCAGGGCCCCGGCGCGCTGCGCGAACTCGGCCGCCTCAT
TGCCCCGGTGGGCTCCCGCGCTTTGCTGGTGTCGGACCGCATCATGAGCGGCATGCTCGCGCCGCGCATCGCCCCGCTGC
TGGAGGCGGAGGGCATCGCCTTCGCCGCCACCGGCTTCGACGGCGATGTCACCCACGCCAATGTCGATCGGATGGTGGCG
GACGGCACGCCGCTGGCGCCGGACGTGGTCATCGCTGCCGGCGGCGGCAAGGGCATGGATGCGGGCAAGGCGGTGTGCCG
CGCCTTCGGCGCCCGGCTGGTGAGCCTGCCCACCGCCGCCTCCAACGACGGCCCCACCAGCCGCAACTTCGTGTTCTATG
ACGACCATCACAAGCTGCTCTCGGTGGAGAAGCTGGTCCGCAATCCGGACCTGGTGCTGGTGGATACCGACCTCATCATC
AAGGCGCCGGCCGCCCTGCTGGTCTCTGGCATCGGCGATGCGCTGGTGAAGCGCTTTGAGGCCGAGCAGGCGGTGGGCGC
CGATGGCCCCAACATGTTCGGAGCACGGGCGACGCTCGCCTCCCTCACCCTCGCGCAGCGCTGCGACGAGGTGCTGCGGG
CGGACGCCGTGGCGGCCCTCGCCGCCGTGCGCTCAAACCGGCCGGGACCGGAATTCGAGCGGGTGATCGAGGCCTGCTTC
CTGCTGGCCGGCCTCGGCTTCGAGGGGTCGGGCCTGTCCATCGCCCACGCCATGACGCGCGGCCTCTCCGCGATCCCGGC
CACGGCGGCGACCCTGCACGGCTGCCAGGTCGCCTATGCCCTGCTGGTGCAGCTCATGCTGGAGCGCCGGCCGCCCGAAT
TCATGGCCGAGCAGTTCGCCTTCTACCGGTCGGTGGGCCTACCCGTCAGCCTGCGCGACCTCGGGCTGGCATCCGCCGCC
CGTGCCGACCTGGAGGTGATCGCCGAGCTGAGCCACCGGGCGCCGCACACGAAGAACTTCGAGCGCGCCCTCACCCCCGC
CGACTTCGTGGATGCGATGGAGCAGCTGGAGGCCATTGGTCTTATGTGA

Upstream 100 bases:

>100_bases
ATCCCCTATCTGCAGACCCGCTATGGCCTCACCGCCGCGCGGGTGCGCGAGCAGGTGGCGCAGTGGCTCGGCGCCGGCGC
GCAGGCGGCGGAGTAGCACC

Downstream 100 bases:

>100_bases
TCGCCCCCAATCAATCGCGACGGGGATGTCCCGTTGCCGCGGTGCCGGCGAGGTCCGGCGGGAACAGGCCGGCCTGGAAG
CAGGTGCTCATGTGCTCCAC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH; GlyDH [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MRELKVFGAPGLYVQGPGALRELGRLIAPVGSRALLVSDRIMSGMLAPRIAPLLEAEGIAFAATGFDGDVTHANVDRMVA
DGTPLAPDVVIAAGGGKGMDAGKAVCRAFGARLVSLPTAASNDGPTSRNFVFYDDHHKLLSVEKLVRNPDLVLVDTDLII
KAPAALLVSGIGDALVKRFEAEQAVGADGPNMFGARATLASLTLAQRCDEVLRADAVAALAAVRSNRPGPEFERVIEACF
LLAGLGFEGSGLSIAHAMTRGLSAIPATAATLHGCQVAYALLVQLMLERRPPEFMAEQFAFYRSVGLPVSLRDLGLASAA
RADLEVIAELSHRAPHTKNFERALTPADFVDAMEQLEAIGLM

Sequences:

>Translated_362_residues
MRELKVFGAPGLYVQGPGALRELGRLIAPVGSRALLVSDRIMSGMLAPRIAPLLEAEGIAFAATGFDGDVTHANVDRMVA
DGTPLAPDVVIAAGGGKGMDAGKAVCRAFGARLVSLPTAASNDGPTSRNFVFYDDHHKLLSVEKLVRNPDLVLVDTDLII
KAPAALLVSGIGDALVKRFEAEQAVGADGPNMFGARATLASLTLAQRCDEVLRADAVAALAAVRSNRPGPEFERVIEACF
LLAGLGFEGSGLSIAHAMTRGLSAIPATAATLHGCQVAYALLVQLMLERRPPEFMAEQFAFYRSVGLPVSLRDLGLASAA
RADLEVIAELSHRAPHTKNFERALTPADFVDAMEQLEAIGLM
>Mature_362_residues
MRELKVFGAPGLYVQGPGALRELGRLIAPVGSRALLVSDRIMSGMLAPRIAPLLEAEGIAFAATGFDGDVTHANVDRMVA
DGTPLAPDVVIAAGGGKGMDAGKAVCRAFGARLVSLPTAASNDGPTSRNFVFYDDHHKLLSVEKLVRNPDLVLVDTDLII
KAPAALLVSGIGDALVKRFEAEQAVGADGPNMFGARATLASLTLAQRCDEVLRADAVAALAAVRSNRPGPEFERVIEACF
LLAGLGFEGSGLSIAHAMTRGLSAIPATAATLHGCQVAYALLVQLMLERRPPEFMAEQFAFYRSVGLPVSLRDLGLASAA
RADLEVIAELSHRAPHTKNFERALTPADFVDAMEQLEAIGLM

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates, such as propan-1,2-diol, butan-

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=325, Percent_Identity=34.1538461538462, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1786815, Length=367, Percent_Identity=26.7029972752044, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 38058; Mature: 38058

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00913 ADH_IRON_1 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELKVFGAPGLYVQGPGALRELGRLIAPVGSRALLVSDRIMSGMLAPRIAPLLEAEGIA
CCCEEEECCCCCEEECCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCE
FAATGFDGDVTHANVDRMVADGTPLAPDVVIAAGGGKGMDAGKAVCRAFGARLVSLPTAA
EEEECCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
SNDGPTSRNFVFYDDHHKLLSVEKLVRNPDLVLVDTDLIIKAPAALLVSGIGDALVKRFE
CCCCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHH
AEQAVGADGPNMFGARATLASLTLAQRCDEVLRADAVAALAAVRSNRPGPEFERVIEACF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLAGLGFEGSGLSIAHAMTRGLSAIPATAATLHGCQVAYALLVQLMLERRPPEFMAEQFA
HHHCCCCCCCCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FYRSVGLPVSLRDLGLASAARADLEVIAELSHRAPHTKNFERALTPADFVDAMEQLEAIG
HHHHCCCCEEHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHC
LM
CC
>Mature Secondary Structure
MRELKVFGAPGLYVQGPGALRELGRLIAPVGSRALLVSDRIMSGMLAPRIAPLLEAEGIA
CCCEEEECCCCCEEECCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCE
FAATGFDGDVTHANVDRMVADGTPLAPDVVIAAGGGKGMDAGKAVCRAFGARLVSLPTAA
EEEECCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
SNDGPTSRNFVFYDDHHKLLSVEKLVRNPDLVLVDTDLIIKAPAALLVSGIGDALVKRFE
CCCCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHH
AEQAVGADGPNMFGARATLASLTLAQRCDEVLRADAVAALAAVRSNRPGPEFERVIEACF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLAGLGFEGSGLSIAHAMTRGLSAIPATAATLHGCQVAYALLVQLMLERRPPEFMAEQFA
HHHCCCCCCCCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FYRSVGLPVSLRDLGLASAARADLEVIAELSHRAPHTKNFERALTPADFVDAMEQLEAIG
HHHHCCCCEEHHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHC
LM
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339360 [H]