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The map label for this gene is ppnK [H]

Identifier: 154245587

GI number: 154245587

Start: 1861969

End: 1862835

Strand: Direct

Name: ppnK [H]

Synonym: Xaut_1643

Alternate gene names: 154245587

Gene position: 1861969-1862835 (Clockwise)

Preceding gene: 154245586

Following gene: 154245588

Centisome position: 35.07

GC content: 69.55

Gene sequence:

>867_bases
ATGGCGGCCGGGCCGTTAGACCTCAAGCCCCATTCCCCGCGAGGCCGGCGCTCAGCGCCGGATGCCGACCAGGCCGCCGC
ACCGATGAGCGCAGCTCCCCGCCGCTTCAACAAGATCGCCTTCGTCGCCAGCCAGACGCCCGAGGCGGAGTCTGCCCGGG
AGCGGCTGATGGCGCGCTACGGCGCGGTGGAGCAGGAGGATGCGGATGTCATTGTCGCCCTCGGCGGCGACGGCCTGATG
CTGCAGACCCTGCACCGCTTCCGTGATCGCGGCCTGCCCATCTACGGCATGCATCGCGGCTCGGTGGGCTTCCTCATGAA
TACCTTCCGGGAGGAGGGGCTGGTGGAGCGCCTCACCGCCGCCCTGCAGGTGACCATCCATCCCCTCATCATGGAGGCGG
TGGACGCCAGCGGCACCCGCCACCGGGCGCCGGCCTTCAACGAGGTGTCGCTGCTGCGCCAGACCTACCAGGCGGCGAAG
CTGCGCATCTCCATCGACGGCCGGGTGCGGCTGGAGGAATTGATCTGCGACGGCGTCATCGTGGCGACGCCGGCAGGCTC
CACCGCCTACAACCTCTCCGCCCATGGGCCGATCCTGCCGCTCGGCACGGCGCTGCTTGCGCTCACCCCCATCTCGCCGT
TCCGCCCCCGCCGCTGGCGCGGGGCGCTGGTTCCGGACAAGGCGCGTATCGACATCGCGGTGATGGAGGCCGACAAGCGC
CCAGTGAGCGCGGCGGCGGACCATTTCGAGGTGCGCGACATCATCGCCGTGTCGGCCCGGCTCGACGCCACGTCCTCCAT
CGACATGCTGTTCGATCCGGACCACGGTCTGGAGGAACGTATCCTGCGCGAGCAATTCGTGTATTAG

Upstream 100 bases:

>100_bases
CCCGATCGAGCGGCTCTTCATAACCGATGGCCGGCCTGCGGCGAAGGTGGCCGCCGAAGCCCCTGCGCATGGCACCCCGC
CCGCGCCCATGCCTCGACAG

Downstream 100 bases:

>100_bases
AGGCGGCGCGGCGGACCTGCTTGGGTCCAGACTGATGGCGCGCTCCCGCGTGCCCGCGTCGAAAAGGGCACAACGGCTTC
CGGCGGTCCATGGTCTTCTC

Product: NAD(+) kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAAGPLDLKPHSPRGRRSAPDADQAAAPMSAAPRRFNKIAFVASQTPEAESARERLMARYGAVEQEDADVIVALGGDGLM
LQTLHRFRDRGLPIYGMHRGSVGFLMNTFREEGLVERLTAALQVTIHPLIMEAVDASGTRHRAPAFNEVSLLRQTYQAAK
LRISIDGRVRLEELICDGVIVATPAGSTAYNLSAHGPILPLGTALLALTPISPFRPRRWRGALVPDKARIDIAVMEADKR
PVSAAADHFEVRDIIAVSARLDATSSIDMLFDPDHGLEERILREQFVY

Sequences:

>Translated_288_residues
MAAGPLDLKPHSPRGRRSAPDADQAAAPMSAAPRRFNKIAFVASQTPEAESARERLMARYGAVEQEDADVIVALGGDGLM
LQTLHRFRDRGLPIYGMHRGSVGFLMNTFREEGLVERLTAALQVTIHPLIMEAVDASGTRHRAPAFNEVSLLRQTYQAAK
LRISIDGRVRLEELICDGVIVATPAGSTAYNLSAHGPILPLGTALLALTPISPFRPRRWRGALVPDKARIDIAVMEADKR
PVSAAADHFEVRDIIAVSARLDATSSIDMLFDPDHGLEERILREQFVY
>Mature_287_residues
AAGPLDLKPHSPRGRRSAPDADQAAAPMSAAPRRFNKIAFVASQTPEAESARERLMARYGAVEQEDADVIVALGGDGLML
QTLHRFRDRGLPIYGMHRGSVGFLMNTFREEGLVERLTAALQVTIHPLIMEAVDASGTRHRAPAFNEVSLLRQTYQAAKL
RISIDGRVRLEELICDGVIVATPAGSTAYNLSAHGPILPLGTALLALTPISPFRPRRWRGALVPDKARIDIAVMEADKRP
VSAAADHFEVRDIIAVSARLDATSSIDMLFDPDHGLEERILREQFVY

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=159, Percent_Identity=32.0754716981132, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=29.3388429752066, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325068, Length=191, Percent_Identity=32.4607329842932, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31503; Mature: 31371

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGPLDLKPHSPRGRRSAPDADQAAAPMSAAPRRFNKIAFVASQTPEAESARERLMARY
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCHHHCEEEEEECCCCCHHHHHHHHHHHH
GAVEQEDADVIVALGGDGLMLQTLHRFRDRGLPIYGMHRGSVGFLMNTFREEGLVERLTA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
ALQVTIHPLIMEAVDASGTRHRAPAFNEVSLLRQTYQAAKLRISIDGRVRLEELICDGVI
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCEEHHHHHHCCEE
VATPAGSTAYNLSAHGPILPLGTALLALTPISPFRPRRWRGALVPDKARIDIAVMEADKR
EECCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCC
PVSAAADHFEVRDIIAVSARLDATSSIDMLFDPDHGLEERILREQFVY
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AAGPLDLKPHSPRGRRSAPDADQAAAPMSAAPRRFNKIAFVASQTPEAESARERLMARY
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCHHHCEEEEEECCCCCHHHHHHHHHHHH
GAVEQEDADVIVALGGDGLMLQTLHRFRDRGLPIYGMHRGSVGFLMNTFREEGLVERLTA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
ALQVTIHPLIMEAVDASGTRHRAPAFNEVSLLRQTYQAAKLRISIDGRVRLEELICDGVI
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCEEHHHHHHCCEE
VATPAGSTAYNLSAHGPILPLGTALLALTPISPFRPRRWRGALVPDKARIDIAVMEADKR
EECCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCC
PVSAAADHFEVRDIIAVSARLDATSSIDMLFDPDHGLEERILREQFVY
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA