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The map label for this gene is xerD [H]

Identifier: 154245579

GI number: 154245579

Start: 1852788

End: 1853852

Strand: Direct

Name: xerD [H]

Synonym: Xaut_1634

Alternate gene names: 154245579

Gene position: 1852788-1853852 (Clockwise)

Preceding gene: 154245577

Following gene: 154245581

Centisome position: 34.9

GC content: 72.77

Gene sequence:

>1065_bases
ATGAGCGGCGAAGGGCTGCCCCAAAATGGGCCGCCCGAAGAGGGGGCGCCCGAAAAGGCATCTTCCAGGAAGGACCTTGC
CGCATCCGGGCCGCTGGCGCTGTTCCTGGACATGCAGGCGATCGAGCGCGGCGGCGGCCCCAACACCCTCGACGCCTATC
GCCGCGACCTGACCGACCTTGCCGAATTCCTCGCCCCCGTGTCCCTCGCCGAGGCCGACACCAGCGCGATCCGCGCCTAT
CTCGCGGACCTGTCGGCGCGGGGCTTCGCCGCCACCACGGTGGCGCGGCGGCTGTCGGCCCTGCGCCAGTTCTACCGCTT
CCTGTTCGCCGAGGGCCACCGCGCCGACGATCCCGCCGCCGTGCTGGAAGGCCCGAAGCGCGGGCGGCCCCTGCCCAAGG
TGCTGAGCGTGGCCGAGGTCACCCGCCTCATCGATACCGCCCATGCGCGCGCCGCCCAGGCCGAGGAGAGCCTGAATGCG
GGGCAGGGGGGCGAAGGGCAGGGCGAAGAGACGCCGGGGGCGGGCGCGGCGAAGGCCGGTCGCGCCGAGCTGCTGCGGCT
GCGGCGGGTCGCCTGCATGGTGGAGCTGCTGTATGCCAGCGGGCTGCGCGTGTCCGAGCTGGTGGCGCTGCCCGCCGCTG
CCGCGCGTGCGCAGGGGGAGGCCATCCTCGTCACCGGCAAGGGGCGCAAGGAACGCCTCGTCCCGCTCTCCGGACCGGCG
AAGGTGGCCATGCAGGCCTTCCTCGCCGCGCGGCGAGCGGCGGGGCTGGAGGCCTCGCGCTGGCTGTTTCCGTCCGGCAG
CGAGAGTGGTCACGTCACCCGCCAGCAGGCGGCACGGGACCTGAAGGAGCTGGCACTGGCGGCGGGGCTCGATCCGGCGA
AGCTGTCGCCCCACGTGCTGCGCCATGCCTTCGCCAGCCATCTTCTGGCCCATGGCGCGGACCTGCGGGTGGTGCAGACC
CTGCTCGGCCATGCCGATGTCTCCACCACCCAGATCTACACCCACGTCCTGGACGAGCGCCTGAAGAGCATGGTGCGCGA
CCTGCACCCGCTGTCGGACGAATGA

Upstream 100 bases:

>100_bases
TGTGCGGCCTCGCCTATGCGGCCCTCTGGGCGCTCGCCAACAAGGTGGAGCCGCAGCAGCGCGAGATCACCTTCACTGTT
CCCGCCGAGAAGATCGGCAA

Downstream 100 bases:

>100_bases
GCCGTCAGAACCGCGTCACCACGGCGGCGAGGTCGGGGCGGGGGCGGTCCTCCAGCTTCTGGGTGGCGGTGCCGATATAG
ATGAAGCCGGTGATGCGCTC

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSGEGLPQNGPPEEGAPEKASSRKDLAASGPLALFLDMQAIERGGGPNTLDAYRRDLTDLAEFLAPVSLAEADTSAIRAY
LADLSARGFAATTVARRLSALRQFYRFLFAEGHRADDPAAVLEGPKRGRPLPKVLSVAEVTRLIDTAHARAAQAEESLNA
GQGGEGQGEETPGAGAAKAGRAELLRLRRVACMVELLYASGLRVSELVALPAAAARAQGEAILVTGKGRKERLVPLSGPA
KVAMQAFLAARRAAGLEASRWLFPSGSESGHVTRQQAARDLKELALAAGLDPAKLSPHVLRHAFASHLLAHGADLRVVQT
LLGHADVSTTQIYTHVLDERLKSMVRDLHPLSDE

Sequences:

>Translated_354_residues
MSGEGLPQNGPPEEGAPEKASSRKDLAASGPLALFLDMQAIERGGGPNTLDAYRRDLTDLAEFLAPVSLAEADTSAIRAY
LADLSARGFAATTVARRLSALRQFYRFLFAEGHRADDPAAVLEGPKRGRPLPKVLSVAEVTRLIDTAHARAAQAEESLNA
GQGGEGQGEETPGAGAAKAGRAELLRLRRVACMVELLYASGLRVSELVALPAAAARAQGEAILVTGKGRKERLVPLSGPA
KVAMQAFLAARRAAGLEASRWLFPSGSESGHVTRQQAARDLKELALAAGLDPAKLSPHVLRHAFASHLLAHGADLRVVQT
LLGHADVSTTQIYTHVLDERLKSMVRDLHPLSDE
>Mature_353_residues
SGEGLPQNGPPEEGAPEKASSRKDLAASGPLALFLDMQAIERGGGPNTLDAYRRDLTDLAEFLAPVSLAEADTSAIRAYL
ADLSARGFAATTVARRLSALRQFYRFLFAEGHRADDPAAVLEGPKRGRPLPKVLSVAEVTRLIDTAHARAAQAEESLNAG
QGGEGQGEETPGAGAAKAGRAELLRLRRVACMVELLYASGLRVSELVALPAAAARAQGEAILVTGKGRKERLVPLSGPAK
VAMQAFLAARRAAGLEASRWLFPSGSESGHVTRQQAARDLKELALAAGLDPAKLSPHVLRHAFASHLLAHGADLRVVQTL
LGHADVSTTQIYTHVLDERLKSMVRDLHPLSDE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=320, Percent_Identity=42.5, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1790244, Length=319, Percent_Identity=31.6614420062696, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37464; Mature: 37333

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEGLPQNGPPEEGAPEKASSRKDLAASGPLALFLDMQAIERGGGPNTLDAYRRDLTDL
CCCCCCCCCCCCCCCCCCHHCCCCCHHCCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHH
AEFLAPVSLAEADTSAIRAYLADLSARGFAATTVARRLSALRQFYRFLFAEGHRADDPAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VLEGPKRGRPLPKVLSVAEVTRLIDTAHARAAQAEESLNAGQGGEGQGEETPGAGAAKAG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
RAELLRLRRVACMVELLYASGLRVSELVALPAAAARAQGEAILVTGKGRKERLVPLSGPA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHH
KVAMQAFLAARRAAGLEASRWLFPSGSESGHVTRQQAARDLKELALAAGLDPAKLSPHVL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHH
RHAFASHLLAHGADLRVVQTLLGHADVSTTQIYTHVLDERLKSMVRDLHPLSDE
HHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SGEGLPQNGPPEEGAPEKASSRKDLAASGPLALFLDMQAIERGGGPNTLDAYRRDLTDL
CCCCCCCCCCCCCCCCCHHCCCCCHHCCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHH
AEFLAPVSLAEADTSAIRAYLADLSARGFAATTVARRLSALRQFYRFLFAEGHRADDPAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VLEGPKRGRPLPKVLSVAEVTRLIDTAHARAAQAEESLNAGQGGEGQGEETPGAGAAKAG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
RAELLRLRRVACMVELLYASGLRVSELVALPAAAARAQGEAILVTGKGRKERLVPLSGPA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHH
KVAMQAFLAARRAAGLEASRWLFPSGSESGHVTRQQAARDLKELALAAGLDPAKLSPHVL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHH
RHAFASHLLAHGADLRVVQTLLGHADVSTTQIYTHVLDERLKSMVRDLHPLSDE
HHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]