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The map label for this gene is aroB [H]

Identifier: 154245578

GI number: 154245578

Start: 1850567

End: 1852351

Strand: Reverse

Name: aroB [H]

Synonym: Xaut_1633

Alternate gene names: 154245578

Gene position: 1852351-1850567 (Counterclockwise)

Preceding gene: 154245580

Following gene: 154245576

Centisome position: 34.89

GC content: 71.54

Gene sequence:

>1785_bases
GTGACGCCTGCCCCGGTGACACCTGCTCCGGTGACGCCTGCCGACATGGTCCGCCGCCTCGGGCGCCGCTCCATCGTGCT
GGTGGGCATGCCGGGGGCCGGCAAGTCGTCGGTGGGCCGCAGGCTCGCCAAGCGGCTCGGCCTGCCCTTCGTGGATGCCG
ACGAGGAGATCGAGCGCGCCGCCTGCATGAGCATTCCGGAAATCTTCGCCCGCCGTGGCGAGGTGGAGTTCCGCGAGGGC
GAGAAGCGGGTAGTGGCGCGGCTGCTCCAGTCCGGCCCCAGCGTGCTCGCCACCGGCGGCGGCGCCTTCATGAACAGTGA
GACCCGCGACGCGGTGGCCCGCCAGGGCGTCTCGGTCTGGCTGCGTGCCGACCTCCACACCCTGCTCAGGCGTGTGAAGA
AGCGCACCGACCGCCCCCTCCTTGCCCAGGGCGACCCGGCGGCGAAGCTCGCCACCCTGCTGCAGCAGCGCGGCGACACC
TACGCCCTCGCCGACGTGATCGTGGACAGCCGCGACGTGGTGCACGAGATGGTGGTGGAAGAGGTGATCGGCGCCGTGCA
CCGCCATCTCATCCAGTATCCCGAAGGGACCCGTTCCATGTCCGCCCCTATTGGTCCCGCCGCCCTCGGCCCCGCCGATC
TGGCCCATGCCGAGCCCGAGCCCCTGCCCGTCGGCGACATCACCCGCAGCACCGTGCGCGTGGATCTGGCCGGGCGGCCC
TATGACATCTATATCGGCCCCGGCCTGCTGGCCGAGGCGGGCACCCATGTGACCGTGCTGCGCAAGGGCGCGCGGGTCGC
CATCGTCACCGACGCCAACGTGGCGGCCGCCGGGCACCTGAAGACGGTTCAGGACTCGCTATCCGCCGCCGGCATCGACC
ATACGGCCATCGTGGTGGAGCCGGGCGAGAAGACCAAGGGCTGGCCCGGCCTCCAGCAGGTGGTGGAAGGCCTGATTTCC
GCCCGCATTGAGCGGCGCGACCTGGTGCTGGCGCTGGGTGGCGGCGTGGTGGGCGACCTCGCGGGCTTCGCCGCCTCGGT
GCTGCGGCGCGGGGTGGACGTGGTGCAGGCGCCGACCACCCTGCTCAGCCAGGTGGACTCTTCCGTCGGCGGTAAGACCG
GCATCAACTCGCCCCAGGGCAAGAACCTGGTCGGCGCCTTCCACCAGCCGGTGCTGGTGTTGGCCGATACCGCAGCGCTG
GACACCCTGCCCGTGCGCGAGGTGCGCGCCGGCTATGCGGAAGTGGTGAAATACGGCCTGCTCGGCGACCGCGCCCTGTT
CGACACGCTGGAGCGCGACTTCGCCGGCGTCATCAATGGCGGGCCGGAGCGCATCTCGGCCGTGGCGGCGAGCTGCATGG
CCAAGGCCGCCATCGTCGCCCGCGACGAGAAGGAGACCGGCGACCGGGCGCTTCTCAACCTCGGCCACACCTTCGGCCAC
GCGCTGGAGGCGGGCGCCGGCTATTCCAGCCGCCTGCTGCACGGCGAGGGCGTCGCCATCGGCATGGCGCTGGCCTTCGC
CTTCTCGGCGCGACTCGGCCTGTGCCCGGGACAGGACGTGACGCGGGCGGTGCGGCACCTGGAAGCCGCCGGCCTGCCCA
CGAAGATTTCCGACGTGCCGGGCGAATTGCCGGACACGGACGGGCTGATGGCCCTCATCGCCCAGGACAAGAAGGTCAGC
CGCGGCGCACTCACCTTCATCCTGGTGCGCGGCATCGGCGAGGCCTTCGTGGCCAAGGACGTGAACCCGGACGAGGTGCG
CGCCTTCCTGGCGGAGATGCGCTGA

Upstream 100 bases:

>100_bases
GACCCAGAACAGCCCCCCGTCCCGCAGGGACACCGAGAGCACCGAAGCCGGGACCAGCGAAGCCGCCGAGGCCGCGCCCG
CCTCCCTTACGCCTGCCCCG

Downstream 100 bases:

>100_bases
GGCGCCCCCCTGTCGAAATTCAAAGGGGTATTCCCGCGCTCACGCTCGTCATGCCCGGGCTTGTCCCCGAAGTCGGCTGT
TGCCGACTTCGGCTCCCCGG

Product: shikimate kinase., 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTPAPVTPAPVTPADMVRRLGRRSIVLVGMPGAGKSSVGRRLAKRLGLPFVDADEEIERAACMSIPEIFARRGEVEFREG
EKRVVARLLQSGPSVLATGGGAFMNSETRDAVARQGVSVWLRADLHTLLRRVKKRTDRPLLAQGDPAAKLATLLQQRGDT
YALADVIVDSRDVVHEMVVEEVIGAVHRHLIQYPEGTRSMSAPIGPAALGPADLAHAEPEPLPVGDITRSTVRVDLAGRP
YDIYIGPGLLAEAGTHVTVLRKGARVAIVTDANVAAAGHLKTVQDSLSAAGIDHTAIVVEPGEKTKGWPGLQQVVEGLIS
ARIERRDLVLALGGGVVGDLAGFAASVLRRGVDVVQAPTTLLSQVDSSVGGKTGINSPQGKNLVGAFHQPVLVLADTAAL
DTLPVREVRAGYAEVVKYGLLGDRALFDTLERDFAGVINGGPERISAVAASCMAKAAIVARDEKETGDRALLNLGHTFGH
ALEAGAGYSSRLLHGEGVAIGMALAFAFSARLGLCPGQDVTRAVRHLEAAGLPTKISDVPGELPDTDGLMALIAQDKKVS
RGALTFILVRGIGEAFVAKDVNPDEVRAFLAEMR

Sequences:

>Translated_594_residues
MTPAPVTPAPVTPADMVRRLGRRSIVLVGMPGAGKSSVGRRLAKRLGLPFVDADEEIERAACMSIPEIFARRGEVEFREG
EKRVVARLLQSGPSVLATGGGAFMNSETRDAVARQGVSVWLRADLHTLLRRVKKRTDRPLLAQGDPAAKLATLLQQRGDT
YALADVIVDSRDVVHEMVVEEVIGAVHRHLIQYPEGTRSMSAPIGPAALGPADLAHAEPEPLPVGDITRSTVRVDLAGRP
YDIYIGPGLLAEAGTHVTVLRKGARVAIVTDANVAAAGHLKTVQDSLSAAGIDHTAIVVEPGEKTKGWPGLQQVVEGLIS
ARIERRDLVLALGGGVVGDLAGFAASVLRRGVDVVQAPTTLLSQVDSSVGGKTGINSPQGKNLVGAFHQPVLVLADTAAL
DTLPVREVRAGYAEVVKYGLLGDRALFDTLERDFAGVINGGPERISAVAASCMAKAAIVARDEKETGDRALLNLGHTFGH
ALEAGAGYSSRLLHGEGVAIGMALAFAFSARLGLCPGQDVTRAVRHLEAAGLPTKISDVPGELPDTDGLMALIAQDKKVS
RGALTFILVRGIGEAFVAKDVNPDEVRAFLAEMR
>Mature_593_residues
TPAPVTPAPVTPADMVRRLGRRSIVLVGMPGAGKSSVGRRLAKRLGLPFVDADEEIERAACMSIPEIFARRGEVEFREGE
KRVVARLLQSGPSVLATGGGAFMNSETRDAVARQGVSVWLRADLHTLLRRVKKRTDRPLLAQGDPAAKLATLLQQRGDTY
ALADVIVDSRDVVHEMVVEEVIGAVHRHLIQYPEGTRSMSAPIGPAALGPADLAHAEPEPLPVGDITRSTVRVDLAGRPY
DIYIGPGLLAEAGTHVTVLRKGARVAIVTDANVAAAGHLKTVQDSLSAAGIDHTAIVVEPGEKTKGWPGLQQVVEGLISA
RIERRDLVLALGGGVVGDLAGFAASVLRRGVDVVQAPTTLLSQVDSSVGGKTGINSPQGKNLVGAFHQPVLVLADTAALD
TLPVREVRAGYAEVVKYGLLGDRALFDTLERDFAGVINGGPERISAVAASCMAKAAIVARDEKETGDRALLNLGHTFGHA
LEAGAGYSSRLLHGEGVAIGMALAFAFSARLGLCPGQDVTRAVRHLEAAGLPTKISDVPGELPDTDGLMALIAQDKKVSR
GALTFILVRGIGEAFVAKDVNPDEVRAFLAEMR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=364, Percent_Identity=42.3076923076923, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082255, Length=164, Percent_Identity=36.5853658536585, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786587, Length=161, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320332, Length=365, Percent_Identity=33.972602739726, Blast_Score=171, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 62475; Mature: 62343

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAPVTPAPVTPADMVRRLGRRSIVLVGMPGAGKSSVGRRLAKRLGLPFVDADEEIERA
CCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
ACMSIPEIFARRGEVEFREGEKRVVARLLQSGPSVLATGGGAFMNSETRDAVARQGVSVW
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCHHEE
LRADLHTLLRRVKKRTDRPLLAQGDPAAKLATLLQQRGDTYALADVIVDSRDVVHEMVVE
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHH
EVIGAVHRHLIQYPEGTRSMSAPIGPAALGPADLAHAEPEPLPVGDITRSTVRVDLAGRP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCC
YDIYIGPGLLAEAGTHVTVLRKGARVAIVTDANVAAAGHLKTVQDSLSAAGIDHTAIVVE
EEEEECCCHHHHCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
PGEKTKGWPGLQQVVEGLISARIERRDLVLALGGGVVGDLAGFAASVLRRGVDVVQAPTT
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHH
LLSQVDSSVGGKTGINSPQGKNLVGAFHQPVLVLADTAALDTLPVREVRAGYAEVVKYGL
HHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHC
LGDRALFDTLERDFAGVINGGPERISAVAASCMAKAAIVARDEKETGDRALLNLGHTFGH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ALEAGAGYSSRLLHGEGVAIGMALAFAFSARLGLCPGQDVTRAVRHLEAAGLPTKISDVP
HHHCCCCCHHCEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
GELPDTDGLMALIAQDKKVSRGALTFILVRGIGEAFVAKDVNPDEVRAFLAEMR
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TPAPVTPAPVTPADMVRRLGRRSIVLVGMPGAGKSSVGRRLAKRLGLPFVDADEEIERA
CCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
ACMSIPEIFARRGEVEFREGEKRVVARLLQSGPSVLATGGGAFMNSETRDAVARQGVSVW
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCHHEE
LRADLHTLLRRVKKRTDRPLLAQGDPAAKLATLLQQRGDTYALADVIVDSRDVVHEMVVE
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHH
EVIGAVHRHLIQYPEGTRSMSAPIGPAALGPADLAHAEPEPLPVGDITRSTVRVDLAGRP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCC
YDIYIGPGLLAEAGTHVTVLRKGARVAIVTDANVAAAGHLKTVQDSLSAAGIDHTAIVVE
EEEEECCCHHHHCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
PGEKTKGWPGLQQVVEGLISARIERRDLVLALGGGVVGDLAGFAASVLRRGVDVVQAPTT
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHH
LLSQVDSSVGGKTGINSPQGKNLVGAFHQPVLVLADTAALDTLPVREVRAGYAEVVKYGL
HHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHC
LGDRALFDTLERDFAGVINGGPERISAVAASCMAKAAIVARDEKETGDRALLNLGHTFGH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ALEAGAGYSSRLLHGEGVAIGMALAFAFSARLGLCPGQDVTRAVRHLEAAGLPTKISDVP
HHHCCCCCHHCEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
GELPDTDGLMALIAQDKKVSRGALTFILVRGIGEAFVAKDVNPDEVRAFLAEMR
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA