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The map label for this gene is rssA [H]

Identifier: 154245479

GI number: 154245479

Start: 1739795

End: 1741204

Strand: Reverse

Name: rssA [H]

Synonym: Xaut_1532

Alternate gene names: 154245479

Gene position: 1741204-1739795 (Counterclockwise)

Preceding gene: 154245480

Following gene: 154245472

Centisome position: 32.8

GC content: 71.91

Gene sequence:

>1410_bases
ATGCGCATTGAGAGCCTGCGCCTCCAGCTCCTGTGCTGGCTGCTGCTGCCGCTGGCGGGGCTGGTGGCGCTCAACGTGTG
GACCAGCGGACGGCAGGCCCGCGCCACCGCCGACCTCGTCACCGACCGCACGCTGGATGCCTCCGTCCGCGCCATCGCCG
AGGATGTGCGCCTCGACCGCGGGGTCATCGACGCCACCATCCCGCCGGTGGCGCTGGAGATGTTCGACACCGGCCACCGC
GACCGGGTCTTTTACCGTGTGGACACGGCGGAAGGACGGCTCCTGACCGGATATCCGGACCTGCCCCGGCCGAAGGCGAC
GCCGAAGGAAGGCGTTCCCCTGCATTTCTCCGCCCCCTATCGCGACCAGCATCTGCGCCTTGCCGCGCTCCAGTATCCGG
TTGTGGGCGCCCATGACGGCGAACGCGTAACCGTTGTGGTCGGCGTGACTCTGGCAGGGCACGCCGCCATGGTGCGCGAA
TTGTGGGTGGGCGGCTTCAGCCAGCAACTGGTGCTGCTCGCCGCCGCAGGCCTCCTCGTGCTGGTGGGCTTGCGCCAGGG
CCTCGCGCCACTGCTGCGCCTGCGCGACACGGTGATGAACAAGGGCCGCGACGACCTCGCCCCCATCCCCGACGCAGCGG
TGCAGAGCGAGCTGCGGCCGCTGGTCGCCGCCCTCAACACCTATATGGCCCGCGTGGAAGGGCAGATGGCGGCTCAGCGC
CGCTTCGTCGCCAATGCGGCGCACCAGTTGCGCACGCCGCTGGCGCTGCTCGCCACCCAGGTCACCTATGCCCGTCGCAC
CCCGGATGCGGCCGAGCGCGAGGAGGCCCTGTCCGGCGTTCAGGAGAGCACGCGGCGCCTCGCCCGCCTCGCCAGCCAGT
TGCTCACCCTGTCCCGCTCGGAACCCGGCAGCCGACGGCCGCGCGACGAGGAGATCGACCTTTCAGCGTCCGCCAGGCTC
GTGCTGGAAGGGCTGGTGGACCTCGCCATCGAGCGCGGCATCGACCTCGCCCTGGACGCGGATGCGCCCGTGCTCACCCG
GGGCGACGGCGCCATGACCCGCGAGGCCATCGTGAATCTGGTGGAGAACGCCCTGCGCTATACCCCCGCCGGCGGCAGCG
TCGCGGTGAGCGTGCGCGCGGAGGACGACTGGGCCGTGCTGGCGGTGGAGGATTCCGGGCCGGGCATCCCACCGCAGGAG
CGCGACAAGGTGTGGGAGCGCTTCTACCGGGTGCCGGGCACGCCCGGCGAGGGCTCCGGCATCGGCCTGTCCATCGTGCG
GGAGGTGGTGGACGGCGCCGGCGGGACGCTCACCCTCGGCACTGCGGAGGCCGGCGGTCTGAAGGTGGAAATGCGGCTAC
CGGCAGCTTCCGCCGCCGGCAGGCTGGAGGATGGCATCCGGGGCGCCTGA

Upstream 100 bases:

>100_bases
AGCGCCATCGAGATCTATGTGCACCGCGTGCGCAAGAAGCTGGAGGGCAGCGACGTGCGCATCGTCACCCTGCGCGGCCT
CGGCTACCTGCTGCAGCACG

Downstream 100 bases:

>100_bases
CCGCCAGACCGGATGCCACCGCTCGCAGGGAAGGTCGCCGATGGTGACCCGTTCCTCAGTTCTGCTCGCTGTAGGGCACG
GGCCGCCACTTCACGAGCCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MRIESLRLQLLCWLLLPLAGLVALNVWTSGRQARATADLVTDRTLDASVRAIAEDVRLDRGVIDATIPPVALEMFDTGHR
DRVFYRVDTAEGRLLTGYPDLPRPKATPKEGVPLHFSAPYRDQHLRLAALQYPVVGAHDGERVTVVVGVTLAGHAAMVRE
LWVGGFSQQLVLLAAAGLLVLVGLRQGLAPLLRLRDTVMNKGRDDLAPIPDAAVQSELRPLVAALNTYMARVEGQMAAQR
RFVANAAHQLRTPLALLATQVTYARRTPDAAEREEALSGVQESTRRLARLASQLLTLSRSEPGSRRPRDEEIDLSASARL
VLEGLVDLAIERGIDLALDADAPVLTRGDGAMTREAIVNLVENALRYTPAGGSVAVSVRAEDDWAVLAVEDSGPGIPPQE
RDKVWERFYRVPGTPGEGSGIGLSIVREVVDGAGGTLTLGTAEAGGLKVEMRLPAASAAGRLEDGIRGA

Sequences:

>Translated_469_residues
MRIESLRLQLLCWLLLPLAGLVALNVWTSGRQARATADLVTDRTLDASVRAIAEDVRLDRGVIDATIPPVALEMFDTGHR
DRVFYRVDTAEGRLLTGYPDLPRPKATPKEGVPLHFSAPYRDQHLRLAALQYPVVGAHDGERVTVVVGVTLAGHAAMVRE
LWVGGFSQQLVLLAAAGLLVLVGLRQGLAPLLRLRDTVMNKGRDDLAPIPDAAVQSELRPLVAALNTYMARVEGQMAAQR
RFVANAAHQLRTPLALLATQVTYARRTPDAAEREEALSGVQESTRRLARLASQLLTLSRSEPGSRRPRDEEIDLSASARL
VLEGLVDLAIERGIDLALDADAPVLTRGDGAMTREAIVNLVENALRYTPAGGSVAVSVRAEDDWAVLAVEDSGPGIPPQE
RDKVWERFYRVPGTPGEGSGIGLSIVREVVDGAGGTLTLGTAEAGGLKVEMRLPAASAAGRLEDGIRGA
>Mature_469_residues
MRIESLRLQLLCWLLLPLAGLVALNVWTSGRQARATADLVTDRTLDASVRAIAEDVRLDRGVIDATIPPVALEMFDTGHR
DRVFYRVDTAEGRLLTGYPDLPRPKATPKEGVPLHFSAPYRDQHLRLAALQYPVVGAHDGERVTVVVGVTLAGHAAMVRE
LWVGGFSQQLVLLAAAGLLVLVGLRQGLAPLLRLRDTVMNKGRDDLAPIPDAAVQSELRPLVAALNTYMARVEGQMAAQR
RFVANAAHQLRTPLALLATQVTYARRTPDAAEREEALSGVQESTRRLARLASQLLTLSRSEPGSRRPRDEEIDLSASARL
VLEGLVDLAIERGIDLALDADAPVLTRGDGAMTREAIVNLVENALRYTPAGGSVAVSVRAEDDWAVLAVEDSGPGIPPQE
RDKVWERFYRVPGTPGEGSGIGLSIVREVVDGAGGTLTLGTAEAGGLKVEMRLPAASAAGRLEDGIRGA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=312, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1786783, Length=339, Percent_Identity=30.0884955752212, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786600, Length=309, Percent_Identity=31.7152103559871, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=29.0909090909091, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790551, Length=270, Percent_Identity=31.4814814814815, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790861, Length=341, Percent_Identity=27.8592375366569, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=30.0411522633745, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=24.3333333333333, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=28.8065843621399, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789808, Length=306, Percent_Identity=29.7385620915033, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=24.4897959183673, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=27.9661016949153, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=30.7116104868914, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=251, Percent_Identity=27.4900398406374, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=23.8866396761134, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=25.4464285714286, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=26.2931034482759, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787374, Length=244, Percent_Identity=25.8196721311475, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=306, Percent_Identity=25.8169934640523, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=22.1739130434783, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50339; Mature: 50339

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIESLRLQLLCWLLLPLAGLVALNVWTSGRQARATADLVTDRTLDASVRAIAEDVRLDR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GVIDATIPPVALEMFDTGHRDRVFYRVDTAEGRLLTGYPDLPRPKATPKEGVPLHFSAPY
CCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEECCC
RDQHLRLAALQYPVVGAHDGERVTVVVGVTLAGHAAMVRELWVGGFSQQLVLLAAAGLLV
CCCCEEEEEEECCEEECCCCCEEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVGLRQGLAPLLRLRDTVMNKGRDDLAPIPDAAVQSELRPLVAALNTYMARVEGQMAAQR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFVANAAHQLRTPLALLATQVTYARRTPDAAEREEALSGVQESTRRLARLASQLLTLSRS
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPGSRRPRDEEIDLSASARLVLEGLVDLAIERGIDLALDADAPVLTRGDGAMTREAIVNL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCHHHHHHHHH
VENALRYTPAGGSVAVSVRAEDDWAVLAVEDSGPGIPPQERDKVWERFYRVPGTPGEGSG
HHHHHHCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
IGLSIVREVVDGAGGTLTLGTAEAGGLKVEMRLPAASAAGRLEDGIRGA
CHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCHHCCHHCCCCCCC
>Mature Secondary Structure
MRIESLRLQLLCWLLLPLAGLVALNVWTSGRQARATADLVTDRTLDASVRAIAEDVRLDR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GVIDATIPPVALEMFDTGHRDRVFYRVDTAEGRLLTGYPDLPRPKATPKEGVPLHFSAPY
CCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEECCC
RDQHLRLAALQYPVVGAHDGERVTVVVGVTLAGHAAMVRELWVGGFSQQLVLLAAAGLLV
CCCCEEEEEEECCEEECCCCCEEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVGLRQGLAPLLRLRDTVMNKGRDDLAPIPDAAVQSELRPLVAALNTYMARVEGQMAAQR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFVANAAHQLRTPLALLATQVTYARRTPDAAEREEALSGVQESTRRLARLASQLLTLSRS
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPGSRRPRDEEIDLSASARLVLEGLVDLAIERGIDLALDADAPVLTRGDGAMTREAIVNL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCHHHHHHHHH
VENALRYTPAGGSVAVSVRAEDDWAVLAVEDSGPGIPPQERDKVWERFYRVPGTPGEGSG
HHHHHHCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
IGLSIVREVVDGAGGTLTLGTAEAGGLKVEMRLPAASAAGRLEDGIRGA
CHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA